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The map label for this gene is ttdA [C]

Identifier: 84489159

GI number: 84489159

Start: 399294

End: 400136

Strand: Direct

Name: ttdA [C]

Synonym: Msp_0338

Alternate gene names: 84489159

Gene position: 399294-400136 (Clockwise)

Preceding gene: 84489158

Following gene: 84489166

Centisome position: 22.59

GC content: 32.74

Gene sequence:

>843_bases
ATGATTACTCAAGAACAAATTGCAAATGCAGTATGTGAAATATACAAAGAAGCTGCAATAATATTGCCAACAGATGTTAA
AAATGCACTTAAAAATGCTTATGATGTTGAAGAAAGCGATATTGCTAAGTTAAATATCAAATCTATACTAGATAATATTG
ATATAGCAGAAGAAAAAGGCATACCTATGTGTCAGGATACAGGTTTACCAATAATATTTGTAAAACTAGGAAAAGTAGAA
GTGGAAAATCTTCAGGAAGGAATAATTGAAGGGGTAAAAAAAGCTACACAGACAGTACCTCTTAGAACAAATGTGGTAGA
CCCACTAACAAGAAAAAATACTGGAAATAACATAGGTAAATCAATTCCACAAATAAATGTTGAATTGTCAGATAAACCAG
AACTTGAATTAACAGTATTTCCTAAGGGATTTGGTTCAGAAAACAATAATAAATTAGCAATGCTCCTACCAGGAGAGGGA
ATTGATGGAATTAAAAAATTCTTTAAAGAAGCAATAATATCAGCAGGAGGAAAACCATGTCCACCTACAGTAATAGGTGT
AGGTATTGGAGGTTCATCTGACATGGTAATGAAACTAGCAAAGAAAGCATTACTTAGACCAGTAGGAGATAAAAATGAGG
ATAAAAGATTAGCAAATCTTGAAGATGAATTATTAACAATTGCTAATGATACTGGAATTGGACCTATGGGACTTGGTGGA
AAAACAACAACATTAGGTGTAAATATTGAATTAGCAGATACACATACTGCAGGTTTACCTGTAGGGGTATGTGTTCAATG
TTGGGCTGCAAGACATGCATCAATAACTCTTAAAGATGAATAA

Upstream 100 bases:

>100_bases
AGAACTTTTTTTTTAGAAATTAAATCTAAAACACATTAATATTAGTTTTAACATAATTTTTTAATAACTAACAAAATTTT
TTTTTATTAAGGATGAAAAC

Downstream 100 bases:

>100_bases
ATCTCTTTTCATCTTCATATTTTTTTTTAAAAAATAGTAACTCTTTTTCTAACAATAAATTTTCTATAAAAATTTTTCTA
AAAATAAAAAAAAATGATGG

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MITQEQIANAVCEIYKEAAIILPTDVKNALKNAYDVEESDIAKLNIKSILDNIDIAEEKGIPMCQDTGLPIIFVKLGKVE
VENLQEGIIEGVKKATQTVPLRTNVVDPLTRKNTGNNIGKSIPQINVELSDKPELELTVFPKGFGSENNNKLAMLLPGEG
IDGIKKFFKEAIISAGGKPCPPTVIGVGIGGSSDMVMKLAKKALLRPVGDKNEDKRLANLEDELLTIANDTGIGPMGLGG
KTTTLGVNIELADTHTAGLPVGVCVQCWAARHASITLKDE

Sequences:

>Translated_280_residues
MITQEQIANAVCEIYKEAAIILPTDVKNALKNAYDVEESDIAKLNIKSILDNIDIAEEKGIPMCQDTGLPIIFVKLGKVE
VENLQEGIIEGVKKATQTVPLRTNVVDPLTRKNTGNNIGKSIPQINVELSDKPELELTVFPKGFGSENNNKLAMLLPGEG
IDGIKKFFKEAIISAGGKPCPPTVIGVGIGGSSDMVMKLAKKALLRPVGDKNEDKRLANLEDELLTIANDTGIGPMGLGG
KTTTLGVNIELADTHTAGLPVGVCVQCWAARHASITLKDE
>Mature_280_residues
MITQEQIANAVCEIYKEAAIILPTDVKNALKNAYDVEESDIAKLNIKSILDNIDIAEEKGIPMCQDTGLPIIFVKLGKVE
VENLQEGIIEGVKKATQTVPLRTNVVDPLTRKNTGNNIGKSIPQINVELSDKPELELTVFPKGFGSENNNKLAMLLPGEG
IDGIKKFFKEAIISAGGKPCPPTVIGVGIGGSSDMVMKLAKKALLRPVGDKNEDKRLANLEDELLTIANDTGIGPMGLGG
KTTTLGVNIELADTHTAGLPVGVCVQCWAARHASITLKDE

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=289, Percent_Identity=34.6020761245675, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1790564, Length=283, Percent_Identity=29.6819787985866, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787897, Length=283, Percent_Identity=29.3286219081272, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 29890; Mature: 29890

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITQEQIANAVCEIYKEAAIILPTDVKNALKNAYDVEESDIAKLNIKSILDNIDIAEEKG
CCCHHHHHHHHHHHHHCCEEEEECHHHHHHHHHCCCCCHHHHEEEHHHHHCCCCCHHHCC
IPMCQDTGLPIIFVKLGKVEVENLQEGIIEGVKKATQTVPLRTNVVDPLTRKNTGNNIGK
CCCCCCCCCCEEEEEECCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHC
SIPQINVELSDKPELELTVFPKGFGSENNNKLAMLLPGEGIDGIKKFFKEAIISAGGKPC
CCCEEEEEECCCCCEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCC
PPTVIGVGIGGSSDMVMKLAKKALLRPVGDKNEDKRLANLEDELLTIANDTGIGPMGLGG
CCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHEEEECCCCCCCCCCCC
KTTTLGVNIELADTHTAGLPVGVCVQCWAARHASITLKDE
CEEEEEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MITQEQIANAVCEIYKEAAIILPTDVKNALKNAYDVEESDIAKLNIKSILDNIDIAEEKG
CCCHHHHHHHHHHHHHCCEEEEECHHHHHHHHHCCCCCHHHHEEEHHHHHCCCCCHHHCC
IPMCQDTGLPIIFVKLGKVEVENLQEGIIEGVKKATQTVPLRTNVVDPLTRKNTGNNIGK
CCCCCCCCCCEEEEEECCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHC
SIPQINVELSDKPELELTVFPKGFGSENNNKLAMLLPGEGIDGIKKFFKEAIISAGGKPC
CCCEEEEEECCCCCEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCC
PPTVIGVGIGGSSDMVMKLAKKALLRPVGDKNEDKRLANLEDELLTIANDTGIGPMGLGG
CCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHEEEECCCCCCCCCCCC
KTTTLGVNIELADTHTAGLPVGVCVQCWAARHASITLKDE
CEEEEEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]