Click here to switch to the map view.

The map label for this gene is mrtA

Identifier: 84489142

GI number: 84489142

Start: 379724

End: 381382

Strand: Direct

Name: mrtA

Synonym: Msp_0321

Alternate gene names: 84489142

Gene position: 379724-381382 (Clockwise)

Preceding gene: 84489141

Following gene: 84489143

Centisome position: 21.48

GC content: 39.54

Gene sequence:

>1659_bases
ATGGATAATGAGAAAAAATTATTCTTAAAGGCTTTAAAAGAAAAATTCGATGAAGACCCTGAAGAAGAAAACACTAAATT
TTACTGCTATGGTGGATGGGAACAATCCGCAAGAAAAAGAGAATTTGCTGAAGAAGCTGAAAAAGCTGTAGAAGCACGTG
GAGGATTACCATTCTACAACCCAGATATAGGTGTACCTCTTGGACAAAGAAAATTAATGGCATACCAAGTATCTGGAACA
GACACATATGTAGAAGGAGACGACCTTCACTTCTGTAACAACTCTGCAATTCAACAATTAGTAGACGATATTAAAAGAAC
TGTAATTGTAGGTATGGATACAGCTCACGGTGTACTTGAACAAAGATTAGGTGTAGAAGTTACTCCTGAAACAATCAACG
AATACCTTGAAACAATCAACCACGCACTCCCTGGAGGAGCAGTTGTACAAGAACACATGGTAGAAGTTGACCCTGGATTA
GTAACTGATTCCTACGCAAAAATATTCACTGGTGACGACGACTTATTAGATCAATTAGATCAAAGATTTGTAATCGACAT
CAACAAAGAGTTCCCTGAAGAACAAGCTGAAATGCTCAAAAAATACATAGGTAAAAAAACCTACCAAGTAAGTAGAGTAC
CTACATTAGTAGTACGTGCTTGTGATGGAGGTACAACCTCCAGATGGTCTGCTATGCAAATTGGTATGAGTTTCATTTCT
GCATACAAATTATGTGCAGGAGAAGCAGCTATTGCTGATTTCTCATACGCAGCAAAACACGCAGATGTAATTTCCATGGC
TAGTGCAATGCCATCAAGAAGAGCAAGAGGTCCAAACGAACCTGGAGGTGTAACCTTCGGTGCATTCTCTGATATGGTAC
AAACAAGCAGAGTAACAGATGACCCAGCTGAAGTAACTTTAGAAGTTATTGGTGGAGCAGCACCATTATACGACCAAGTA
TGGTTAGGTTCATACATGTCTGGTGGTGTAGGATTCACACAATATGCTACAGCAGCATACACAGATGAAATATTAGATGA
CTTCATTTACTATGGTAAAGACTACGTAGAAGGTAAATATGGTGGATTATGTCAAGCTGAAGCAACTTCCGAAGTTGTAA
AAGACATTGCAAGTGAAGTAACCTTATACGGATTAGAACAATACGAAATCCCTGCAGCATTAGAAGACCACTTTGGTGGA
TCACAAAGAGCAGCAGTTCTTGCAGCAGGTGCAGGTTGTTCAGTAGCATTCGCAACTGCTAACTCTAACGCAGGTGTAAA
TGGATGGTACTTAAGTCAATTATTACATAAAGAAGGTCACAGTAGATTAGGATTCTATGGTTACGACTTACAAGATCAAT
GTGGATCATCCAACTCACTCTCTGTAAGAAGTGATGAAGGACTTATTCACGAATTAAGAGGTCCTAACTACCCTAACTAC
GCAATGAACGTAGGTCACCAACCTGAATATGCAGGTATTGCTCAAGCACCACACGCAGCAAGAGGAGACGCATTTGCACT
TAACCCATTAATAAAAGTAGCATTTGCTGATAAAAACTTATCCTTCGATTGGGCTCACCCAAGAGAATGTATTGCAAAAG
GTGCTGTTAGAGAATTTATGCCTAGCGGTGAACGTGACTTAATCAACCCAGCTTTATAA

Upstream 100 bases:

>100_bases
TTATTAAAGTAGTTGAAGCTATTCACTTCGCAAGAACTGATGGTGGATATGGTTTAGAAGTATTCAACAACGATTTAAAA
AGTAAATTAGGTGGTAACTA

Downstream 100 bases:

>100_bases
GTTAGTTGATTTTGTTGATAAATATAGGGTTTAGTTTATATAATATGTTGTACATAAATATAGACTGGAGTTTTCCAAGT
AAAAAAATATAAAAGTATTA

Product: hypothetical protein

Products: NA

Alternate protein names: MCR II alpha; Coenzyme-B sulfoethylthiotransferase alpha [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MDNEKKLFLKALKEKFDEDPEEENTKFYCYGGWEQSARKREFAEEAEKAVEARGGLPFYNPDIGVPLGQRKLMAYQVSGT
DTYVEGDDLHFCNNSAIQQLVDDIKRTVIVGMDTAHGVLEQRLGVEVTPETINEYLETINHALPGGAVVQEHMVEVDPGL
VTDSYAKIFTGDDDLLDQLDQRFVIDINKEFPEEQAEMLKKYIGKKTYQVSRVPTLVVRACDGGTTSRWSAMQIGMSFIS
AYKLCAGEAAIADFSYAAKHADVISMASAMPSRRARGPNEPGGVTFGAFSDMVQTSRVTDDPAEVTLEVIGGAAPLYDQV
WLGSYMSGGVGFTQYATAAYTDEILDDFIYYGKDYVEGKYGGLCQAEATSEVVKDIASEVTLYGLEQYEIPAALEDHFGG
SQRAAVLAAGAGCSVAFATANSNAGVNGWYLSQLLHKEGHSRLGFYGYDLQDQCGSSNSLSVRSDEGLIHELRGPNYPNY
AMNVGHQPEYAGIAQAPHAARGDAFALNPLIKVAFADKNLSFDWAHPRECIAKGAVREFMPSGERDLINPAL

Sequences:

>Translated_552_residues
MDNEKKLFLKALKEKFDEDPEEENTKFYCYGGWEQSARKREFAEEAEKAVEARGGLPFYNPDIGVPLGQRKLMAYQVSGT
DTYVEGDDLHFCNNSAIQQLVDDIKRTVIVGMDTAHGVLEQRLGVEVTPETINEYLETINHALPGGAVVQEHMVEVDPGL
VTDSYAKIFTGDDDLLDQLDQRFVIDINKEFPEEQAEMLKKYIGKKTYQVSRVPTLVVRACDGGTTSRWSAMQIGMSFIS
AYKLCAGEAAIADFSYAAKHADVISMASAMPSRRARGPNEPGGVTFGAFSDMVQTSRVTDDPAEVTLEVIGGAAPLYDQV
WLGSYMSGGVGFTQYATAAYTDEILDDFIYYGKDYVEGKYGGLCQAEATSEVVKDIASEVTLYGLEQYEIPAALEDHFGG
SQRAAVLAAGAGCSVAFATANSNAGVNGWYLSQLLHKEGHSRLGFYGYDLQDQCGSSNSLSVRSDEGLIHELRGPNYPNY
AMNVGHQPEYAGIAQAPHAARGDAFALNPLIKVAFADKNLSFDWAHPRECIAKGAVREFMPSGERDLINPAL
>Mature_552_residues
MDNEKKLFLKALKEKFDEDPEEENTKFYCYGGWEQSARKREFAEEAEKAVEARGGLPFYNPDIGVPLGQRKLMAYQVSGT
DTYVEGDDLHFCNNSAIQQLVDDIKRTVIVGMDTAHGVLEQRLGVEVTPETINEYLETINHALPGGAVVQEHMVEVDPGL
VTDSYAKIFTGDDDLLDQLDQRFVIDINKEFPEEQAEMLKKYIGKKTYQVSRVPTLVVRACDGGTTSRWSAMQIGMSFIS
AYKLCAGEAAIADFSYAAKHADVISMASAMPSRRARGPNEPGGVTFGAFSDMVQTSRVTDDPAEVTLEVIGGAAPLYDQV
WLGSYMSGGVGFTQYATAAYTDEILDDFIYYGKDYVEGKYGGLCQAEATSEVVKDIASEVTLYGLEQYEIPAALEDHFGG
SQRAAVLAAGAGCSVAFATANSNAGVNGWYLSQLLHKEGHSRLGFYGYDLQDQCGSSNSLSVRSDEGLIHELRGPNYPNY
AMNVGHQPEYAGIAQAPHAARGDAFALNPLIKVAFADKNLSFDWAHPRECIAKGAVREFMPSGERDLINPAL

Specific function: Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and an heterodisulfide [H]

COG id: COG4058

COG function: function code H; Methyl coenzyme M reductase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022681
- InterPro:   IPR016212
- InterPro:   IPR008924
- InterPro:   IPR009047
- InterPro:   IPR003183
- InterPro:   IPR015811
- InterPro:   IPR015823
- InterPro:   IPR009024 [H]

Pfam domain/function: PF02249 MCR_alpha; PF02745 MCR_alpha_N [H]

EC number: =2.8.4.1 [H]

Molecular weight: Translated: 60334; Mature: 60334

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNEKKLFLKALKEKFDEDPEEENTKFYCYGGWEQSARKREFAEEAEKAVEARGGLPFYN
CCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PDIGVPLGQRKLMAYQVSGTDTYVEGDDLHFCNNSAIQQLVDDIKRTVIVGMDTAHGVLE
CCCCCCCCCCEEEEEEECCCCEEECCCCCEECCHHHHHHHHHHHHHHEEEECCHHHHHHH
QRLGVEVTPETINEYLETINHALPGGAVVQEHMVEVDPGLVTDSYAKIFTGDDDLLDQLD
HHCCCEECHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHC
QRFVIDINKEFPEEQAEMLKKYIGKKTYQVSRVPTLVVRACDGGTTSRWSAMQIGMSFIS
CEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHH
AYKLCAGEAAIADFSYAAKHADVISMASAMPSRRARGPNEPGGVTFGAFSDMVQTSRVTD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCEEHHHHHHHHHHHCCCC
DPAEVTLEVIGGAAPLYDQVWLGSYMSGGVGFTQYATAAYTDEILDDFIYYGKDYVEGKY
CHHHEEHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCC
GGLCQAEATSEVVKDIASEVTLYGLEQYEIPAALEDHFGGSQRAAVLAAGAGCSVAFATA
CCEECHHHHHHHHHHHHHHHEEECCHHHCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEC
NSNAGVNGWYLSQLLHKEGHSRLGFYGYDLQDQCGSSNSLSVRSDEGLIHELRGPNYPNY
CCCCCCCHHHHHHHHHHCCCCCCCEECCCHHHHCCCCCCEEEECCCCHHHHCCCCCCCCH
AMNVGHQPEYAGIAQAPHAARGDAFALNPLIKVAFADKNLSFDWAHPRECIAKGAVREFM
HCCCCCCCCCCCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHC
PSGERDLINPAL
CCCCCCCCCCCC
>Mature Secondary Structure
MDNEKKLFLKALKEKFDEDPEEENTKFYCYGGWEQSARKREFAEEAEKAVEARGGLPFYN
CCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PDIGVPLGQRKLMAYQVSGTDTYVEGDDLHFCNNSAIQQLVDDIKRTVIVGMDTAHGVLE
CCCCCCCCCCEEEEEEECCCCEEECCCCCEECCHHHHHHHHHHHHHHEEEECCHHHHHHH
QRLGVEVTPETINEYLETINHALPGGAVVQEHMVEVDPGLVTDSYAKIFTGDDDLLDQLD
HHCCCEECHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHC
QRFVIDINKEFPEEQAEMLKKYIGKKTYQVSRVPTLVVRACDGGTTSRWSAMQIGMSFIS
CEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHH
AYKLCAGEAAIADFSYAAKHADVISMASAMPSRRARGPNEPGGVTFGAFSDMVQTSRVTD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCEEHHHHHHHHHHHCCCC
DPAEVTLEVIGGAAPLYDQVWLGSYMSGGVGFTQYATAAYTDEILDDFIYYGKDYVEGKY
CHHHEEHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCC
GGLCQAEATSEVVKDIASEVTLYGLEQYEIPAALEDHFGGSQRAAVLAAGAGCSVAFATA
CCEECHHHHHHHHHHHHHHHEEECCHHHCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEC
NSNAGVNGWYLSQLLHKEGHSRLGFYGYDLQDQCGSSNSLSVRSDEGLIHELRGPNYPNY
CCCCCCCHHHHHHHHHHCCCCCCCEECCCHHHHCCCCCCEEEECCCCHHHHCCCCCCCCH
AMNVGHQPEYAGIAQAPHAARGDAFALNPLIKVAFADKNLSFDWAHPRECIAKGAVREFM
HCCCCCCCCCCCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHC
PSGERDLINPAL
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]