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The map label for this gene is murC [H]

Identifier: 83721549

GI number: 83721549

Start: 1263980

End: 1265377

Strand: Direct

Name: murC [H]

Synonym: BTH_I1119

Alternate gene names: 83721549

Gene position: 1263980-1265377 (Clockwise)

Preceding gene: 83719178

Following gene: 83720293

Centisome position: 33.18

GC content: 70.31

Gene sequence:

>1398_bases
ATGAAACACATCGTCAAACACATTCATTTCGTCGGGATCGGCGGCGCGGGCATGAGCGGCATCGCCGAAGTGCTCGTGAA
CCTGGGCTATCAGGTGAGCGGCTCCGATCTCGCGCGCAACGCGGTGACCGAGCGCCTCGAGGCGCTCGGCGCGCGCGTGT
CGATCGGCCACGACGCGGCGAACATCGAGGGCGCGAACGCGGTGGTCGTGTCGACCGCGGTGCGCTCGGACAACCCGGAG
GTGCTCGCCGCGCGCCGCCTGCGCGTGCCGATCGTGCCGCGCGCGGTGATGCTCGCGGAGCTGATGCGCCTGAAGCAGGG
GATCGCGATCGCCGGCACGCACGGCAAGACGACGACGACGAGCCTCGTCGCGAGCGTGCTCGCCGCGGGCGGGCTCGATC
CGACGTTCGTGATCGGCGGGCGTCTCACGAGCGCCGGGGCGAACGCGCGGCTCGGCACGGGCGACTTCATCGTCGCGGAA
GCCGACGAGTCGGACGCGTCGTTCCTGAACCTGTATCCGGTGATCGAGGTCATCACGAACATCGACGCCGATCACATGGA
CACCTACGGCCACGATTTCGCGCGGCTCAAGCAGGCGTTCATCGAATTCACGCAGCGGCTGCCGTTCTACGGCAGCGCCG
TCGTGTGCATCGACGACCCGAACGTGCGGCAGATCGTGCCGCTGATCTCGAAGCCCGTCGTGCGCTACGGCTTCGCGGCG
GATGCGCAGGTGCGCGCGGAGAACGTCGAGGCGCGCGACGGCCGGATGCACTTCACGGTGCTGCGCGAGGGGCGCGAGCC
GCTGCCCGTCGTCCTGAACCTGCCGGGCCTGCACAACGTGCAGAACGCGCTCGCCGCGATCGCGATCGCGACCGATCTCG
ACGTGGCCGACACGGCGATTCAGCAGGCGCTCGCGGAATTCAACGGCGTGGGCCGGCGCTTCCAGCGCTACGGGGAGATG
CCGGCCGCGGGCGGCGGCGCGTACACGCTGATCGACGACTACGGCCACCATCCGGTCGAGATGGCGGCGACGATCGCGGC
GGCGCGCGGCGCGTTCCCGGGCCGCCGGCTCGTGCTCGCTTTCCAGCCGCATCGCTACACGCGCACGCGCGACTGCTTCG
ACGATTTCGTCAACGTGCTGTCGACGGTCGACGCGCTGGTGCTGACCGAGGTGTACGCGGCCGGCGAGGCGCCGATTTCG
ACCGCGAACGGCGATGCGCTGTCGCGCGCGCTGCGCGCGGCGGGCAAGGTCGAGCCGGTATTCGTCGCGACGGTCGACGA
GGTGCCGGACGCGCTCGCGAAGCTCGCGCGCGCCGGCGACGTGGTGATCACGATGGGCGCGGGCTCGATCGGCGGGGTGC
CGGGCAAGCTCGCGCAGGACACGCAACAGAAGGGATGA

Upstream 100 bases:

>100_bases
CGATGGCCGAACGTTCGCGCTCGCTCGCGAAGCCGGATGCCACCGACGAAGTCGCGCGCGTGTGCGCGGCGGTGGCGGGC
GCGAACCTGGAAGGAAAGCA

Downstream 100 bases:

>100_bases
CATGAGCGGGATCGATCCGAAACGTTTCGGCAAGGTGGCGGTGCTGCTCGGCGGGGAATCCGCCGAGCGCGATGTGTCGC
TGAACTCCGGCCGGCTGGTG

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLARNAVTERLEALGARVSIGHDAANIEGANAVVVSTAVRSDNPE
VLAARRLRVPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLTSAGANARLGTGDFIVAE
ADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCIDDPNVRQIVPLISKPVVRYGFAA
DAQVRAENVEARDGRMHFTVLREGREPLPVVLNLPGLHNVQNALAAIAIATDLDVADTAIQQALAEFNGVGRRFQRYGEM
PAAGGGAYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAPIS
TANGDALSRALRAAGKVEPVFVATVDEVPDALAKLARAGDVVITMGAGSIGGVPGKLAQDTQQKG

Sequences:

>Translated_465_residues
MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLARNAVTERLEALGARVSIGHDAANIEGANAVVVSTAVRSDNPE
VLAARRLRVPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLTSAGANARLGTGDFIVAE
ADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCIDDPNVRQIVPLISKPVVRYGFAA
DAQVRAENVEARDGRMHFTVLREGREPLPVVLNLPGLHNVQNALAAIAIATDLDVADTAIQQALAEFNGVGRRFQRYGEM
PAAGGGAYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAPIS
TANGDALSRALRAAGKVEPVFVATVDEVPDALAKLARAGDVVITMGAGSIGGVPGKLAQDTQQKG
>Mature_465_residues
MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLARNAVTERLEALGARVSIGHDAANIEGANAVVVSTAVRSDNPE
VLAARRLRVPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLTSAGANARLGTGDFIVAE
ADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCIDDPNVRQIVPLISKPVVRYGFAA
DAQVRAENVEARDGRMHFTVLREGREPLPVVLNLPGLHNVQNALAAIAIATDLDVADTAIQQALAEFNGVGRRFQRYGEM
PAAGGGAYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAPIS
TANGDALSRALRAAGKVEPVFVATVDEVPDALAKLARAGDVVITMGAGSIGGVPGKLAQDTQQKG

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=459, Percent_Identity=53.8126361655773, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1790680, Length=475, Percent_Identity=29.0526315789474, Blast_Score=171, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 49040; Mature: 49040

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLARNAVTERLEALGARVSIGHDAA
CCCHHHHEEEEEECCCCHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHCCEEEECCCCC
NIEGANAVVVSTAVRSDNPEVLAARRLRVPIVPRAVMLAELMRLKQGIAIAGTHGKTTTT
CCCCCCEEEEEEEECCCCCCEEEHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCHHH
SLVASVLAAGGLDPTFVIGGRLTSAGANARLGTGDFIVAEADESDASFLNLYPVIEVITN
HHHHHHHHHCCCCCEEEECCEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
IDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCIDDPNVRQIVPLISKPVVRYGFAA
CCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCHHHHCCCC
DAQVRAENVEARDGRMHFTVLREGREPLPVVLNLPGLHNVQNALAAIAIATDLDVADTAI
CCEEECCCCCCCCCCEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHH
QQALAEFNGVGRRFQRYGEMPAAGGGAYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLA
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEE
FQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAPISTANGDALSRALRAAGKVEPV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEE
FVATVDEVPDALAKLARAGDVVITMGAGSIGGVPGKLAQDTQQKG
EEEEHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLARNAVTERLEALGARVSIGHDAA
CCCHHHHEEEEEECCCCHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHCCEEEECCCCC
NIEGANAVVVSTAVRSDNPEVLAARRLRVPIVPRAVMLAELMRLKQGIAIAGTHGKTTTT
CCCCCCEEEEEEEECCCCCCEEEHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCHHH
SLVASVLAAGGLDPTFVIGGRLTSAGANARLGTGDFIVAEADESDASFLNLYPVIEVITN
HHHHHHHHHCCCCCEEEECCEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
IDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCIDDPNVRQIVPLISKPVVRYGFAA
CCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCHHHHCCCC
DAQVRAENVEARDGRMHFTVLREGREPLPVVLNLPGLHNVQNALAAIAIATDLDVADTAI
CCEEECCCCCCCCCCEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHH
QQALAEFNGVGRRFQRYGEMPAAGGGAYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLA
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEE
FQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAPISTANGDALSRALRAAGKVEPV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEE
FVATVDEVPDALAKLARAGDVVITMGAGSIGGVPGKLAQDTQQKG
EEEEHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA