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The map label for this gene is moaA [H]

Identifier: 83721219

GI number: 83721219

Start: 1914223

End: 1915335

Strand: Reverse

Name: moaA [H]

Synonym: BTH_I1706

Alternate gene names: 83721219

Gene position: 1915335-1914223 (Counterclockwise)

Preceding gene: 83719665

Following gene: 83719973

Centisome position: 50.28

GC content: 67.3

Gene sequence:

>1113_bases
ATGTCCCGACGCATCATTCCTGTGACCCCGGTGAGCACGACACCCGATCTGTCCGGCGCGCTGCTCGCGCCGAACGGCAC
GCTGCGCGACGCCCTGGCACGCCCGCTGCGCGACCTGCGCATCTCAGTCACGGACCGCTGCAACTTCCGATGCGTGTACT
GCATGCCGCGCACCGTATTCGGCAAGGATTACCCGTTCCTGCCGCACAGCGCGTTGCTGACGCTCGAGGAAATCGAGCGC
CTCGCGCGACTTTTCGTCGCACACGGCGTCGAGAAGATCCGCATCACGGGCGGCGAGCCGCTCTTGCGCAAGAACATCGA
ATTCCTGATCGAGCGCTTGGCGAAAATGACGACCGTCGACGGCCGTGCGCTCGACATCACGCTGACGACGAACGGCTCGC
TGCTCGTGCGCAAGGCGAAGAGCCTGCGCGACGCGGGGCTCTCGCGCGTGACGGTCAGCCTCGACGCGCTCGACGACACG
CTCTTCAAACGCATGAACGATGCCGATTTCGCGAGCGCCGACGTGCTCGACGGCATCTTCGCCGCGCATGCGGCGGGCCT
TTCTCCCGTGAAGGTCAACATGGTCGTCAAGCGCGGCACGAACGACGCCGAGATCGTGCCGATGGCACGCCGCTTCAAGG
GCACGGGCGTCGTGCTGCGCTTCATCGAGTACATGGACGTCGGCACGTCGAACGGCTGGAACATGGCCGAAGTGCTGCCG
TCCGCCGACGTGATCGCGCGCATCGCCGAGCATTTCCCGCTCGTGCCGCTCGAGCGCAACACGCGTTCCGAGACCGCGCA
GCGTTGGGGCTATGCGGACGGCAGCGGCGAGATCGGCGTGATCTCGAGCGTCACGCGCGCGTTCTGCGGCGATTGCACGC
GCGCGCGACTGTCGACCGAGGGCCGGCTGTATCTGTGCCTCTTCGCATCGTCCGGCCACGACCTGCGCAGCCTCGTGCGC
GGCGGCGCGACCGACGAGCAGATCGCCGCGCTGATCGGCCACATCTGGCAGGCGCGCACCGACCGCTACTCGCAACTGCG
CGGCAGCGCGCAAGCGACGGAGGAAGCGCTCGGCGAAGCGAAGCGCGTCGAAATGTCCTACATCGGCGGCTAG

Upstream 100 bases:

>100_bases
GCGGGCTTTTTTGTCTGTGCTCCGGTTCTGCGGGTTTCCATGCCCGGCCCCATGCGGCGCTTCCGGCTAAAATGGAACTC
TGACTTATCTTGCAACGCTC

Downstream 100 bases:

>100_bases
GCCCGCCCGCGCCACGCGCCCCCGCTCTCGCCATGTCGTCGCGCACCGCGCCCGCTTCCCCGATCACCGGCCTGCTGCTC
GCGGGCGGACGCGGCACGCG

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSRRIIPVTPVSTTPDLSGALLAPNGTLRDALARPLRDLRISVTDRCNFRCVYCMPRTVFGKDYPFLPHSALLTLEEIER
LARLFVAHGVEKIRITGGEPLLRKNIEFLIERLAKMTTVDGRALDITLTTNGSLLVRKAKSLRDAGLSRVTVSLDALDDT
LFKRMNDADFASADVLDGIFAAHAAGLSPVKVNMVVKRGTNDAEIVPMARRFKGTGVVLRFIEYMDVGTSNGWNMAEVLP
SADVIARIAEHFPLVPLERNTRSETAQRWGYADGSGEIGVISSVTRAFCGDCTRARLSTEGRLYLCLFASSGHDLRSLVR
GGATDEQIAALIGHIWQARTDRYSQLRGSAQATEEALGEAKRVEMSYIGG

Sequences:

>Translated_370_residues
MSRRIIPVTPVSTTPDLSGALLAPNGTLRDALARPLRDLRISVTDRCNFRCVYCMPRTVFGKDYPFLPHSALLTLEEIER
LARLFVAHGVEKIRITGGEPLLRKNIEFLIERLAKMTTVDGRALDITLTTNGSLLVRKAKSLRDAGLSRVTVSLDALDDT
LFKRMNDADFASADVLDGIFAAHAAGLSPVKVNMVVKRGTNDAEIVPMARRFKGTGVVLRFIEYMDVGTSNGWNMAEVLP
SADVIARIAEHFPLVPLERNTRSETAQRWGYADGSGEIGVISSVTRAFCGDCTRARLSTEGRLYLCLFASSGHDLRSLVR
GGATDEQIAALIGHIWQARTDRYSQLRGSAQATEEALGEAKRVEMSYIGG
>Mature_369_residues
SRRIIPVTPVSTTPDLSGALLAPNGTLRDALARPLRDLRISVTDRCNFRCVYCMPRTVFGKDYPFLPHSALLTLEEIERL
ARLFVAHGVEKIRITGGEPLLRKNIEFLIERLAKMTTVDGRALDITLTTNGSLLVRKAKSLRDAGLSRVTVSLDALDDTL
FKRMNDADFASADVLDGIFAAHAAGLSPVKVNMVVKRGTNDAEIVPMARRFKGTGVVLRFIEYMDVGTSNGWNMAEVLPS
ADVIARIAEHFPLVPLERNTRSETAQRWGYADGSGEIGVISSVTRAFCGDCTRARLSTEGRLYLCLFASSGHDLRSLVRG
GATDEQIAALIGHIWQARTDRYSQLRGSAQATEEALGEAKRVEMSYIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=306, Percent_Identity=36.9281045751634, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI22027536, Length=306, Percent_Identity=36.9281045751634, Blast_Score=198, Evalue=7e-51,
Organism=Escherichia coli, GI1786999, Length=347, Percent_Identity=32.8530259365994, Blast_Score=169, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI32566331, Length=324, Percent_Identity=32.7160493827161, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI32566329, Length=346, Percent_Identity=32.0809248554913, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17561210, Length=345, Percent_Identity=31.8840579710145, Blast_Score=171, Evalue=8e-43,
Organism=Drosophila melanogaster, GI28574488, Length=332, Percent_Identity=34.6385542168675, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI28574490, Length=325, Percent_Identity=35.0769230769231, Blast_Score=182, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 40525; Mature: 40394

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRIIPVTPVSTTPDLSGALLAPNGTLRDALARPLRDLRISVTDRCNFRCVYCMPRTVF
CCCCEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHCEEEEECCCCEEEEEECCHHHC
GKDYPFLPHSALLTLEEIERLARLFVAHGVEKIRITGGEPLLRKNIEFLIERLAKMTTVD
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCC
GRALDITLTTNGSLLVRKAKSLRDAGLSRVTVSLDALDDTLFKRMNDADFASADVLDGIF
CCEEEEEEECCCCEEEHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHH
AAHAAGLSPVKVNMVVKRGTNDAEIVPMARRFKGTGVVLRFIEYMDVGTSNGWNMAEVLP
HHHHCCCCCEEEEEEEECCCCCCCEEHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHCC
SADVIARIAEHFPLVPLERNTRSETAQRWGYADGSGEIGVISSVTRAFCGDCTRARLSTE
CHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCC
GRLYLCLFASSGHDLRSLVRGGATDEQIAALIGHIWQARTDRYSQLRGSAQATEEALGEA
CCEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHH
KRVEMSYIGG
HHEEEEECCC
>Mature Secondary Structure 
SRRIIPVTPVSTTPDLSGALLAPNGTLRDALARPLRDLRISVTDRCNFRCVYCMPRTVF
CCCEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHCEEEEECCCCEEEEEECCHHHC
GKDYPFLPHSALLTLEEIERLARLFVAHGVEKIRITGGEPLLRKNIEFLIERLAKMTTVD
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCC
GRALDITLTTNGSLLVRKAKSLRDAGLSRVTVSLDALDDTLFKRMNDADFASADVLDGIF
CCEEEEEEECCCCEEEHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHH
AAHAAGLSPVKVNMVVKRGTNDAEIVPMARRFKGTGVVLRFIEYMDVGTSNGWNMAEVLP
HHHHCCCCCEEEEEEEECCCCCCCEEHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHCC
SADVIARIAEHFPLVPLERNTRSETAQRWGYADGSGEIGVISSVTRAFCGDCTRARLSTE
CHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCC
GRLYLCLFASSGHDLRSLVRGGATDEQIAALIGHIWQARTDRYSQLRGSAQATEEALGEA
CCEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHH
KRVEMSYIGG
HHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]