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The map label for this gene is pntB [H]

Identifier: 83721084

GI number: 83721084

Start: 1408151

End: 1409605

Strand: Direct

Name: pntB [H]

Synonym: BTH_I1261

Alternate gene names: 83721084

Gene position: 1408151-1409605 (Clockwise)

Preceding gene: 83719043

Following gene: 83719467

Centisome position: 36.97

GC content: 65.57

Gene sequence:

>1455_bases
ATGAGCATGAATGTCGTCACGCTGCTGTATCTCGTTGCGTCGGTGTGCTTCATCCAGGCGCTGAAGGGGCTGTCGAACCC
GAAGAGCGCTAGACGAGGCAATCTATTCGGCATGGTCGGCATGGCGATCGCGATCCTCACGACCGTCGCGCTGATCGCGA
AGCAGGCCGCGTGGCTCGGCGCGAACCTGCCGCTCGGTTTGGGGCTCGTGTTCGGCGCGCTCGTGATCGGCGGCGCGGTG
GGCGCGGTGATCGCCGCGCGCGTCGAGATGACGAAGATGCCGGAGCTCGTCGCGGCGATGCACTCGCTGATCGGTCTCGC
GGCCGTGTGCATCGCGATCGCGGTGGTCGCGGAGCCGGAGGCGTTCGGCCTCGTGCCGCAGGACGCGACGTTGCCGAACT
TCATCCCGTACGGCAACCGGATCGAGCTCTTCATCGGCACGTTCGTCGGCGCGATCACGTTCTCGGGCTCGGTGATCGCG
TTCGGCAAGCTGTCGGGCAAGTACAAGTTCCGGCTGTTCCAGGGCGCGCCCGTCGTCTATCCCGGCCAGCATCTGATCAA
CCTGATGCTCGCGCTCGCGATGCTCGGCTTCGGCATCCTGTTCTTCGTCACGCAATCGTGGCTGCCGTTCGGGATCATGA
CGGCGATCGCGTTCGCGCTCGGCGTGCTGATCATCATCCCGATCGGCGGCGCGGACATGCCGGTCGTCGTGTCGATGCTG
AACTCGTACTCGGGGTGGGCGGCGGCGGGCATCGGCTTCTCGCTGAACAACGCGATGCTGATCATCGCCGGCTCGCTCGT
CGGCTCGTCGGGCGCGATCCTGTCGTACATCATGTGCCATGCGATGAACCGCTCGTTCTTCAACGTGATCCTCGGCGGCT
TCGGCGGCGATGCGGCCGCGGCGACGGCGGGCGGCGCGAAGGAGCAGCGGCCGGTGAAGTCGGGCTCGGCGGAGGATGCG
GCGTTCATGCTCGGCAACGCGGAATCGGTCGTGATCGTGCCGGGCTATGGGCTGGCGGTCGCGCGCGCGCAGCACGCGCT
GAAGGAGCTCACCGACAAGCTCGTCGAGAAGGGCATCGACGTGCGCTACGCGATCCATCCGGTCGCGGGGCGGATGCCGG
GGCACATGAACGTGCTGCTCGCGGAGGCCGAGGTGCCGTACGAGATCGTCCACGAAATGGAGGACATCAACGGCGAATTC
GGGCAGGTGGACGTGGTGCTCGTGCTCGGGGCGAACGACGTGGTGAATCCGGCCGCGAAGAACGATCCGAAATCGCCGAT
CGCGGGGATGCCGATCATCGAGGCGTACAAGGCGCGCACGGTGATCGTCAACAAGCGCTCGATGGCGGCGGGCTATGCGG
GCCTCGACAACGAGCTCTTCTACATGGACAAGACGATGATGGTCTTCGGCGATGCGAAGAAGGTCATCGAGGATATGGTG
AAGTCGGTCGAGTGA

Upstream 100 bases:

>100_bases
TCAACGTGTTCGGCGGCTTCCTCGTCACGCGGCGCATGCTCGAGATGTTCAAGAAGAAGGAGCCGAAAGAGAAGGCCGGC
CACGCGAAGGAGGGCGCGCG

Downstream 100 bases:

>100_bases
CGCCGTGGGCGGACGCTCGGCCCGCCCACGGGCGGGCGTTCGACGCTTCGCGGATCGCGAGTTGTGAGTTGTGAATTGCG
CCGGTCGGCTTGCGGCCCTT

Product: NAD(P) transhydrogenase subunit beta

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAILTTVALIAKQAAWLGANLPLGLGLVFGALVIGGAV
GAVIAARVEMTKMPELVAAMHSLIGLAAVCIAIAVVAEPEAFGLVPQDATLPNFIPYGNRIELFIGTFVGAITFSGSVIA
FGKLSGKYKFRLFQGAPVVYPGQHLINLMLALAMLGFGILFFVTQSWLPFGIMTAIAFALGVLIIIPIGGADMPVVVSML
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGDAAAATAGGAKEQRPVKSGSAEDA
AFMLGNAESVVIVPGYGLAVARAQHALKELTDKLVEKGIDVRYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEF
GQVDVVLVLGANDVVNPAAKNDPKSPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVIEDMV
KSVE

Sequences:

>Translated_484_residues
MSMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAILTTVALIAKQAAWLGANLPLGLGLVFGALVIGGAV
GAVIAARVEMTKMPELVAAMHSLIGLAAVCIAIAVVAEPEAFGLVPQDATLPNFIPYGNRIELFIGTFVGAITFSGSVIA
FGKLSGKYKFRLFQGAPVVYPGQHLINLMLALAMLGFGILFFVTQSWLPFGIMTAIAFALGVLIIIPIGGADMPVVVSML
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGDAAAATAGGAKEQRPVKSGSAEDA
AFMLGNAESVVIVPGYGLAVARAQHALKELTDKLVEKGIDVRYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEF
GQVDVVLVLGANDVVNPAAKNDPKSPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVIEDMV
KSVE
>Mature_483_residues
SMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAILTTVALIAKQAAWLGANLPLGLGLVFGALVIGGAVG
AVIAARVEMTKMPELVAAMHSLIGLAAVCIAIAVVAEPEAFGLVPQDATLPNFIPYGNRIELFIGTFVGAITFSGSVIAF
GKLSGKYKFRLFQGAPVVYPGQHLINLMLALAMLGFGILFFVTQSWLPFGIMTAIAFALGVLIIIPIGGADMPVVVSMLN
SYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGDAAAATAGGAKEQRPVKSGSAEDAA
FMLGNAESVVIVPGYGLAVARAQHALKELTDKLVEKGIDVRYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEFG
QVDVVLVLGANDVVNPAAKNDPKSPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVIEDMVK
SVE

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=493, Percent_Identity=45.841784989858, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI122939153, Length=493, Percent_Identity=45.841784989858, Blast_Score=400, Evalue=1e-111,
Organism=Escherichia coli, GI1787886, Length=487, Percent_Identity=51.3347022587269, Blast_Score=456, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17550456, Length=487, Percent_Identity=43.5318275154004, Blast_Score=364, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 50673; Mature: 50541

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAILTTVALIAKQAAWLG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
ANLPLGLGLVFGALVIGGAVGAVIAARVEMTKMPELVAAMHSLIGLAAVCIAIAVVAEPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
AFGLVPQDATLPNFIPYGNRIELFIGTFVGAITFSGSVIAFGKLSGKYKFRLFQGAPVVY
HHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCEEE
PGQHLINLMLALAMLGFGILFFVTQSWLPFGIMTAIAFALGVLIIIPIGGADMPVVVSML
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGDAAA
HCCCCCCHHCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCHHH
ATAGGAKEQRPVKSGSAEDAAFMLGNAESVVIVPGYGLAVARAQHALKELTDKLVEKGID
HCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
VRYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEFGQVDVVLVLGANDVVNPAAK
EEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCC
NDPKSPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVIEDMV
CCCCCCCCCCCHHHHHCCEEEEEECHHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHH
KSVE
HHCC
>Mature Secondary Structure 
SMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAILTTVALIAKQAAWLG
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
ANLPLGLGLVFGALVIGGAVGAVIAARVEMTKMPELVAAMHSLIGLAAVCIAIAVVAEPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
AFGLVPQDATLPNFIPYGNRIELFIGTFVGAITFSGSVIAFGKLSGKYKFRLFQGAPVVY
HHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCEEE
PGQHLINLMLALAMLGFGILFFVTQSWLPFGIMTAIAFALGVLIIIPIGGADMPVVVSML
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGDAAA
HCCCCCCHHCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCHHH
ATAGGAKEQRPVKSGSAEDAAFMLGNAESVVIVPGYGLAVARAQHALKELTDKLVEKGID
HCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
VRYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEFGQVDVVLVLGANDVVNPAAK
EEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCC
NDPKSPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVIEDMV
CCCCCCCCCCCHHHHHCCEEEEEECHHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHH
KSVE
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]