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The map label for this gene is obgE [H]

Identifier: 83720969

GI number: 83720969

Start: 1287434

End: 1288552

Strand: Direct

Name: obgE [H]

Synonym: BTH_I1142

Alternate gene names: 83720969

Gene position: 1287434-1288552 (Clockwise)

Preceding gene: 83720039

Following gene: 83721050

Centisome position: 33.8

GC content: 65.86

Gene sequence:

>1119_bases
ATGAAGTTCATTGACGAAGCGCGAATCGAGGTCATCGCCGGGGACGGGGGCGATGGCAGCGCGTCGATGCGCCGCGAGAA
ATTCGTTCCGTTCGGCGGACCGGACGGCGGCGACGGCGGCCGCGGCGGCAGCGTGTACGTGATCGCGGATCGCAACATCA
ATACGCTGATCGACTACCGGTACGCGAAGAAGCACATGGCGCGCAACGGCGAGAACGGCCGCGGCTCGGATTGCTACGGC
AAGGGCGGCGACGACGTCACGCTGCGCATGCCGGTCGGCACCGTCATCAACGACATGGATACGGGCGAGCTGATCGCCGA
TCTGACCGAGCACGACCAGAAGGTGCTCGTCGCGAAGGGCGGCGCGGGCGGCCTCGGCAACCTGCATTTCAAGTCGAGCA
CGAACCGCGCGCCGCGCCAGAAGACGGACGGCAAGCCGGGCGAGCGGCGCATGCTGAAGCTCGAACTGAAGGTGCTCGCG
GACGTCGGCCTGCTCGGGATGCCGAACGCGGGCAAATCGACGTTCATTTCGTCGGTGTCGAACGCGAAGCCGAAGATCGC
CGATTATCCGTTCACGACGCTTGCGCCGAATCTCGGCGTGGTGCGCGTCGGGCCGGGCAAGAGCTTCGTGATCGCCGATA
TTCCGGGTCTGATCGAAGGCGCGGCGGAAGGCGCGGGCCTCGGCCATCAGTTTCTGCGGCATTTGCAGCGCACGGGTTTG
CTGCTGCATCTCGTCGATCTCGCGCCGTTCGATGAAAGCGTCGATCCCGTCGCGGAGGCGAAGGCGATCGTCGGCGAGCT
GCGCAAGTACGACGAATCGCTGTATCAGAAGCCACGCTGGCTCGTGTTGAACAAGCTCGACATGGTGCCGGAGGACGAGC
GCCGCACGCGCGTCGTCGATTTCATCGAGCGCTTCGGCTGGACGGGCCCCGTGTTCGAGATTTCCGCGCTGACGGGGCAG
GGCTGCGAAGGCCTTGTCTATGCGATCTACGATTATCTCGCCGAGCATTCGGATGCGCATCGCGCCGAGCTCGCCGAGGA
TCTGGCTTCGGACGTGCGCTTTCGCGACGCGTCGGGCGCAGGCGGCGAGCCGCACGAGCGCGAAGCCGACGCGCCCTGA

Upstream 100 bases:

>100_bases
AGGCATTCGGCGCGCGCCTCGGCCGTTCGGCCGATTGGTCAAGCGAGGCGCCGCGCGGCACAATAGCGGGAATGGCAGCA
CATACTGGACGGAGTGACGG

Downstream 100 bases:

>100_bases
GCGCCGCGTCCATCGCGAATGGCGCCGGGCGACTCGCCCGGCGTACGAGATTCAATCGCGCATCACTCAAGGAGACAGCG
TACGATGCGTTCGATCATCG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYVIADRNINTLIDYRYAKKHMARNGENGRGSDCYG
KGGDDVTLRMPVGTVINDMDTGELIADLTEHDQKVLVAKGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPGKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHLVDLAPFDESVDPVAEAKAIVGELRKYDESLYQKPRWLVLNKLDMVPEDERRTRVVDFIERFGWTGPVFEISALTGQ
GCEGLVYAIYDYLAEHSDAHRAELAEDLASDVRFRDASGAGGEPHEREADAP

Sequences:

>Translated_372_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYVIADRNINTLIDYRYAKKHMARNGENGRGSDCYG
KGGDDVTLRMPVGTVINDMDTGELIADLTEHDQKVLVAKGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPGKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHLVDLAPFDESVDPVAEAKAIVGELRKYDESLYQKPRWLVLNKLDMVPEDERRTRVVDFIERFGWTGPVFEISALTGQ
GCEGLVYAIYDYLAEHSDAHRAELAEDLASDVRFRDASGAGGEPHEREADAP
>Mature_372_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYVIADRNINTLIDYRYAKKHMARNGENGRGSDCYG
KGGDDVTLRMPVGTVINDMDTGELIADLTEHDQKVLVAKGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPGKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHLVDLAPFDESVDPVAEAKAIVGELRKYDESLYQKPRWLVLNKLDMVPEDERRTRVVDFIERFGWTGPVFEISALTGQ
GCEGLVYAIYDYLAEHSDAHRAELAEDLASDVRFRDASGAGGEPHEREADAP

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=336, Percent_Identity=38.3928571428571, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI111955139, Length=378, Percent_Identity=34.6560846560847, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI111955063, Length=280, Percent_Identity=32.5, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI58761500, Length=136, Percent_Identity=32.3529411764706, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4758796, Length=119, Percent_Identity=34.453781512605, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4557537, Length=121, Percent_Identity=33.0578512396694, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1789574, Length=336, Percent_Identity=58.3333333333333, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=36, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=339, Percent_Identity=37.1681415929204, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=312, Percent_Identity=30.4487179487179, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=33.0935251798561, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71981008, Length=94, Percent_Identity=36.1702127659575, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=182, Percent_Identity=37.9120879120879, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6319281, Length=89, Percent_Identity=37.0786516853933, Blast_Score=63, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6321773, Length=178, Percent_Identity=27.5280898876405, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24585318, Length=303, Percent_Identity=39.6039603960396, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI20129375, Length=336, Percent_Identity=37.5, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24640873, Length=135, Percent_Identity=34.0740740740741, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640877, Length=135, Percent_Identity=34.0740740740741, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640875, Length=135, Percent_Identity=34.0740740740741, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17981711, Length=151, Percent_Identity=30.4635761589404, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356473, Length=87, Percent_Identity=39.0804597701149, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 40117; Mature: 40117

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYVIADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHH
YAKKHMARNGENGRGSDCYGKGGDDVTLRMPVGTVINDMDTGELIADLTEHDQKVLVAKG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCCCHHHHHHHHHHCCCEEEEEEC
GAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
NAKPKIADYPFTTLAPNLGVVRVGPGKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
CCCCCCCCCCHHHHCCCCCEEEECCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHCCC
LLHLVDLAPFDESVDPVAEAKAIVGELRKYDESLYQKPRWLVLNKLDMVPEDERRTRVVD
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHH
FIERFGWTGPVFEISALTGQGCEGLVYAIYDYLAEHSDAHRAELAEDLASDVRFRDASGA
HHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEECCCCC
GGEPHEREADAP
CCCCCCCCCCCC
>Mature Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYVIADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHH
YAKKHMARNGENGRGSDCYGKGGDDVTLRMPVGTVINDMDTGELIADLTEHDQKVLVAKG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCCCHHHHHHHHHHCCCEEEEEEC
GAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
NAKPKIADYPFTTLAPNLGVVRVGPGKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
CCCCCCCCCCHHHHCCCCCEEEECCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHCCC
LLHLVDLAPFDESVDPVAEAKAIVGELRKYDESLYQKPRWLVLNKLDMVPEDERRTRVVD
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHH
FIERFGWTGPVFEISALTGQGCEGLVYAIYDYLAEHSDAHRAELAEDLASDVRFRDASGA
HHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEECCCCC
GGEPHEREADAP
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA