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The map label for this gene is hldE [H]

Identifier: 83720386

GI number: 83720386

Start: 1852307

End: 1853293

Strand: Direct

Name: hldE [H]

Synonym: BTH_I1643

Alternate gene names: 83720386

Gene position: 1852307-1853293 (Clockwise)

Preceding gene: 83721201

Following gene: 83720621

Centisome position: 48.63

GC content: 69.6

Gene sequence:

>987_bases
ATGTCGTGCCCTTCTCTTCCGAGCGCGAATAAGCGCACGGCGCTCGCCGCGACCGCGCGGGCCGTGCCGCGCGAGCAGAT
CGCGAAGTCGCGCGTGCTCGTCGTCGGCGACGTGATGCTCGATCGCTACTGGTTCGGCAACGTCAACCGGATCTCGCCCG
AAGCGCCCGTGCCCGTCGTGCATGTGCAGCGGCAGGAGGAGCGCTTGGGCGGTGCGGCGAACGTCGCGCGCAACGCGGTG
ACGCTCGGCGGCCAGGCAGGCCTGCTGTGCGTGGTCGGGCGCGACGAGCCCGGCGAGCGGATCGTCGAGCTGCTCGGCGA
GAGCGGCGTGACGCCGTATCTCGAGCGAGATCCGGCGCTGCCGACCACGATCAAGCTGCGCGTGCTCGCGCAGCAGCAGC
AATTGCTGCGCGTCGACTTCGAGGCGTCGCCGACGCACGAGGTGTTGCTCGCGGGGCTTGCGCGCTTCGATGCGCTGCTG
CCGTCGTACGACGTCGTGCTGATGTCCGACTACGCGAAGGGCGGCCTCACGCACGTGACGACGATGATTGCGAAAGCGCG
CGCGGCGGGCAAGCCCGTGCTCGTCGATCCGAAGGGCGCCGATTGGGCGCGCTATCGCGGCGCGTCGCTGATCACGCCGA
ATCGCGCGGAGTTGCGCGAGGTCGTTGGGCAGTGGACGTCCGAGGACGATCTGCGCGCGCGCGTCACGAAGCTGCGCGAA
GAACTCGCGCTCGACGCGCTGCTGCTCACGCGCTCGGAAGAGGGGATGACGCTCTTCTCGAACGACGGCGAACTGCACGT
GAGCGCGCTCGCGCGCGAAGTGTACGATGTGTCGGGCGCGGGCGACACGGTGATCGCGACCGTCGCGACGATGCTCGGCG
CGGGGCTGCCGCTCGTCGAAGCGGTGGTGCTCGCGAATCGCGCGGCGGGCATCGTTGTCGGCAAGCTCGGCACCGCGACC
GTCGAGTACGGCGAACTGTTTCATTGA

Upstream 100 bases:

>100_bases
TCGGTGCTGAAAGCGCCCGTGATCTTCGACGGCCGCAACCTGTACGAACCCGACGCGATGGCCGAGCTCGGCATCGATTA
CCACGCTATTGGACGCCCCT

Downstream 100 bases:

>100_bases
ACGGCGACGGCGCGCACCGCCGCGCGCCGTGCGCACACTCTTATCGGCAGAACGATCATGACCCTCATCGTTACCGGCGC
GGCCGGCTTCATCGGCGCGA

Product: D-glycero-D-manno-heptose 1-phosphate synthase

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSCPSLPSANKRTALAATARAVPREQIAKSRVLVVGDVMLDRYWFGNVNRISPEAPVPVVHVQRQEERLGGAANVARNAV
TLGGQAGLLCVVGRDEPGERIVELLGESGVTPYLERDPALPTTIKLRVLAQQQQLLRVDFEASPTHEVLLAGLARFDALL
PSYDVVLMSDYAKGGLTHVTTMIAKARAAGKPVLVDPKGADWARYRGASLITPNRAELREVVGQWTSEDDLRARVTKLRE
ELALDALLLTRSEEGMTLFSNDGELHVSALAREVYDVSGAGDTVIATVATMLGAGLPLVEAVVLANRAAGIVVGKLGTAT
VEYGELFH

Sequences:

>Translated_328_residues
MSCPSLPSANKRTALAATARAVPREQIAKSRVLVVGDVMLDRYWFGNVNRISPEAPVPVVHVQRQEERLGGAANVARNAV
TLGGQAGLLCVVGRDEPGERIVELLGESGVTPYLERDPALPTTIKLRVLAQQQQLLRVDFEASPTHEVLLAGLARFDALL
PSYDVVLMSDYAKGGLTHVTTMIAKARAAGKPVLVDPKGADWARYRGASLITPNRAELREVVGQWTSEDDLRARVTKLRE
ELALDALLLTRSEEGMTLFSNDGELHVSALAREVYDVSGAGDTVIATVATMLGAGLPLVEAVVLANRAAGIVVGKLGTAT
VEYGELFH
>Mature_327_residues
SCPSLPSANKRTALAATARAVPREQIAKSRVLVVGDVMLDRYWFGNVNRISPEAPVPVVHVQRQEERLGGAANVARNAVT
LGGQAGLLCVVGRDEPGERIVELLGESGVTPYLERDPALPTTIKLRVLAQQQQLLRVDFEASPTHEVLLAGLARFDALLP
SYDVVLMSDYAKGGLTHVTTMIAKARAAGKPVLVDPKGADWARYRGASLITPNRAELREVVGQWTSEDDLRARVTKLREE
LALDALLLTRSEEGMTLFSNDGELHVSALAREVYDVSGAGDTVIATVATMLGAGLPLVEAVVLANRAAGIVVGKLGTATV
EYGELFH

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=309, Percent_Identity=49.5145631067961, Blast_Score=268, Evalue=3e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 35116; Mature: 34985

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCPSLPSANKRTALAATARAVPREQIAKSRVLVVGDVMLDRYWFGNVNRISPEAPVPVV
CCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCEEEEEHHHHHHHHCCCCCCCCCCCCCCEE
HVQRQEERLGGAANVARNAVTLGGQAGLLCVVGRDEPGERIVELLGESGVTPYLERDPAL
EECCHHHHCCCHHHHHHHHEEECCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCC
PTTIKLRVLAQQQQLLRVDFEASPTHEVLLAGLARFDALLPSYDVVLMSDYAKGGLTHVT
CCEEEEHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHH
TMIAKARAAGKPVLVDPKGADWARYRGASLITPNRAELREVVGQWTSEDDLRARVTKLRE
HHHHHHHHCCCCEEECCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
ELALDALLLTRSEEGMTLFSNDGELHVSALAREVYDVSGAGDTVIATVATMLGAGLPLVE
HHHHHHHHEECCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHH
AVVLANRAAGIVVGKLGTATVEYGELFH
HHHHHCCCCCEEEECCCCCEECCCCCCC
>Mature Secondary Structure 
SCPSLPSANKRTALAATARAVPREQIAKSRVLVVGDVMLDRYWFGNVNRISPEAPVPVV
CCCCCCCCCCCHHHHHHHHHCCHHHHHHCCEEEEEHHHHHHHHCCCCCCCCCCCCCCEE
HVQRQEERLGGAANVARNAVTLGGQAGLLCVVGRDEPGERIVELLGESGVTPYLERDPAL
EECCHHHHCCCHHHHHHHHEEECCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCC
PTTIKLRVLAQQQQLLRVDFEASPTHEVLLAGLARFDALLPSYDVVLMSDYAKGGLTHVT
CCEEEEHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHH
TMIAKARAAGKPVLVDPKGADWARYRGASLITPNRAELREVVGQWTSEDDLRARVTKLRE
HHHHHHHHCCCCEEECCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
ELALDALLLTRSEEGMTLFSNDGELHVSALAREVYDVSGAGDTVIATVATMLGAGLPLVE
HHHHHHHHEECCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHH
AVVLANRAAGIVVGKLGTATVEYGELFH
HHHHHCCCCCEEEECCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA