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The map label for this gene is hisQ [H]

Identifier: 83720040

GI number: 83720040

Start: 1986207

End: 1986896

Strand: Direct

Name: hisQ [H]

Synonym: BTH_I1771

Alternate gene names: 83720040

Gene position: 1986207-1986896 (Clockwise)

Preceding gene: 83720924

Following gene: 83718785

Centisome position: 52.14

GC content: 63.62

Gene sequence:

>690_bases
GTGTTTCTATACGGCTTTGGTCCGCTCATCTGGGCGGGCACCGTGCAGACGATCGAGCTGTCGGTGCTGTCGCTCGCGGC
GGCGGTGCTGCTCGGCCTCGCCGGTGCAGTCGCGAAGCTCTCGCGCAATCGCGTGTTGCGCGCGGGCGCGACGGCCTACA
CGACGCTCATCCGCTCGGTGCCCGATCTCGTGCTGATGCTGCTGCTGTTCTACAGCATCCAGATCTGGCTCAACCAGCTC
ACCGACCTGATGAACTGGGAGCAGATCGACATCGATCCGTTCGTCGCCGGCGTGCTCACGCTGGGGTTCATCTATGGCGC
GTATTTCACCGAGACGTTTCGCGGCGCGTTCCTCGCGGTGCCGCGCGGACAGCTCGAGGCGGGCAGCGCGTACGGGATGA
GCGGGATGCGCGTGTTCGCGCGGATCATGTTTCCGCAGATGATGCGCTTCGCGCTGCCCGGCATCGGCAACAACTGGCAG
GTGCTCGTGAAGGCGACGGCGCTCGTGTCGATCATCGGTCTCGCCGACGTCGTGAAAGCCGCGCAGGACGCGGGCAAAAG
CACGTTCAACATGTTCTTCTTCATTCTCGTCGCGGCGCTCGTCTATCTGGCGATCACGACGGCCTCCAATCTCGTGCTCA
AGCAGCTCGAGAAGCGTTATTCCATCGGCGTGAGGCACGCGGAACTATGA

Upstream 100 bases:

>100_bases
CGCCACCGCCATTTGAGCGGTTTTTTTTTGCTTGCGACTATCCGCGTCAAACCGGCGCGACCGTGCGTGCGCCATTCCCA
TCACGATCCCGGAGACAAGC

Downstream 100 bases:

>100_bases
TCGAGATCCTGCAGGAATTCGGGCGCGCGTTCTTGTATTGGGACGGCCAGCGCATGTCGGGGCTCGCCGTCACGCTGTGG
CTGCTCGTCGCGTCGCTCGG

Product: amino acid ABC transporter permease

Products: ADP; phosphate; L-histidine [Cytoplasm]; ADP; L-ornithine [Cytoplasm]; L-arginine [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MFLYGFGPLIWAGTVQTIELSVLSLAAAVLLGLAGAVAKLSRNRVLRAGATAYTTLIRSVPDLVLMLLLFYSIQIWLNQL
TDLMNWEQIDIDPFVAGVLTLGFIYGAYFTETFRGAFLAVPRGQLEAGSAYGMSGMRVFARIMFPQMMRFALPGIGNNWQ
VLVKATALVSIIGLADVVKAAQDAGKSTFNMFFFILVAALVYLAITTASNLVLKQLEKRYSIGVRHAEL

Sequences:

>Translated_229_residues
MFLYGFGPLIWAGTVQTIELSVLSLAAAVLLGLAGAVAKLSRNRVLRAGATAYTTLIRSVPDLVLMLLLFYSIQIWLNQL
TDLMNWEQIDIDPFVAGVLTLGFIYGAYFTETFRGAFLAVPRGQLEAGSAYGMSGMRVFARIMFPQMMRFALPGIGNNWQ
VLVKATALVSIIGLADVVKAAQDAGKSTFNMFFFILVAALVYLAITTASNLVLKQLEKRYSIGVRHAEL
>Mature_229_residues
MFLYGFGPLIWAGTVQTIELSVLSLAAAVLLGLAGAVAKLSRNRVLRAGATAYTTLIRSVPDLVLMLLLFYSIQIWLNQL
TDLMNWEQIDIDPFVAGVLTLGFIYGAYFTETFRGAFLAVPRGQLEAGSAYGMSGMRVFARIMFPQMMRFALPGIGNNWQ
VLVKATALVSIIGLADVVKAAQDAGKSTFNMFFFILVAALVYLAITTASNLVLKQLEKRYSIGVRHAEL

Specific function: Part of the binding-protein-dependent transport system for histidine; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4215

COG function: function code E; ABC-type arginine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788646, Length=227, Percent_Identity=61.2334801762115, Blast_Score=278, Evalue=2e-76,
Organism=Escherichia coli, GI1787087, Length=216, Percent_Identity=35.1851851851852, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1787030, Length=215, Percent_Identity=30.6976744186047, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788645, Length=221, Percent_Identity=30.7692307692308, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788226, Length=221, Percent_Identity=27.1493212669683, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1786873, Length=213, Percent_Identity=29.1079812206573, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1786874, Length=181, Percent_Identity=30.939226519337, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082239, Length=220, Percent_Identity=27.7272727272727, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787086, Length=221, Percent_Identity=26.2443438914027, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25026; Mature: 25026

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLYGFGPLIWAGTVQTIELSVLSLAAAVLLGLAGAVAKLSRNRVLRAGATAYTTLIRSV
CCEEECCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
PDLVLMLLLFYSIQIWLNQLTDLMNWEQIDIDPFVAGVLTLGFIYGAYFTETFRGAFLAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PRGQLEAGSAYGMSGMRVFARIMFPQMMRFALPGIGNNWQVLVKATALVSIIGLADVVKA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AQDAGKSTFNMFFFILVAALVYLAITTASNLVLKQLEKRYSIGVRHAEL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFLYGFGPLIWAGTVQTIELSVLSLAAAVLLGLAGAVAKLSRNRVLRAGATAYTTLIRSV
CCEEECCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
PDLVLMLLLFYSIQIWLNQLTDLMNWEQIDIDPFVAGVLTLGFIYGAYFTETFRGAFLAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PRGQLEAGSAYGMSGMRVFARIMFPQMMRFALPGIGNNWQVLVKATALVSIIGLADVVKA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AQDAGKSTFNMFFFILVAALVYLAITTASNLVLKQLEKRYSIGVRHAEL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-histidine [Periplasm]; H2O; ATP; L-ornithine [Periplasm]; L-arginine [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: ATP + L-histidine [Periplasm] + H2O = ADP + phosphate + L-histidine [Cytoplasm] ATP + L-ornithine [Periplasm] + H2O = ADP + phosphate + L-ornithine [Cytoplasm] ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] ATP + L-lysine [P

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]