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The map label for this gene is kdgR [H]

Identifier: 83719970

GI number: 83719970

Start: 1321213

End: 1322265

Strand: Direct

Name: kdgR [H]

Synonym: BTH_I1175

Alternate gene names: 83719970

Gene position: 1321213-1322265 (Clockwise)

Preceding gene: 83720056

Following gene: 83718909

Centisome position: 34.68

GC content: 68.38

Gene sequence:

>1053_bases
ATGAGAGCGACATTCAAATATTGGAGCTTGCAGCACGCCCCTCTACAATCCGAAGCACATCGAAACGCTTCGGCAGATGC
GCGGCCGCCGGAAATCGTCGGCGCGCGCGTCTGGTTCGCCGGAGTTCATCGCACCATGAACAAAACGCCCATGACGCTTG
CCTTGAACGGCGCGACAGCCGACCATTCCGACACGTCGGACCTGCCCGACGCGACGCTCGCCGACAGCATCGGCGCGACG
AGCACGCCGCTCGATCTCGCCGCGCAGCAGGCGGGCACGCAAACGCTGCTGCGCGGGCTCGCGATTCTCGAGGCGGTCGC
GGCAGGCGCGCGCGACATGCGCGCGATCGGCGCCGCGCTCGGCACGACGCGCAGCACGACGCACCGCCTCGTCAGCAGCC
TCGTGCAAGCGCGCTATTTGCGCCAGGTGCAGGGCGGCTATCTGCTCGGCCCGAAGCTGATCGAGCTCGGCACGATCGCA
CTCGAGCAGATGCCGCTCACGGCGGTCGCGCGCCCGCATCTCGAGGCGCTCGCACAAGCGACGCTCGACACGATCCATCT
GGGCGTGCGCGACGGCGACGACGTGCTCTACATCGACAAGATTCCCGGCACGCGCGGCCTCGAGATGCGCTCGCGGATCG
GCCACCGGATGCCGCTCGCGTCGACGGGGATCGGCAAGGCGATGATGCTCGATCTCGATCCCGACACGTGGCGCGCGCTG
TTCGATGCGTCCAAGCGCGCGCTCGCGGGCGTGAACTTCAAGCCAGATCGCCGCCCGGACGTCGGCACGTTCCTGCAGCG
GATGGCGCACTATGCGGCGGGCGGCTACACGTTCGATCTCGAGGAAAACGAAACGTCGATTCGCTGCGTCGCCGCGCCGG
TGCGCGACGCGTCGGGCGCGATCGTCGCCGCTTTGTCGGTGGCGAGCACGATTCCGTACATGTCGCTCGACCGGATGAAC
GAGCTCGTGCCGCTCGTGCAGCGCGGCGCGCGCGCGATCTCGGCCGATCTCGGCTGGAGCGCGCCGCAGGCGACGCGCAG
GATCAAGCGATGA

Upstream 100 bases:

>100_bases
AGCACGGGGCGCGCATCGAACGGGCTCAGCCGGGCAATCGGCTCGGCCCGTTTTTTCATGCGTGCGGCCGGCTCGCGAGT
ATGATCTGGATTCCCAATAT

Downstream 100 bases:

>100_bases
CCGCGCACGCGAACACGCCCGCGCTGATCGGGCTGGACTGGGGCACGACGTCGTTGCGCGCGTATCTGTTCGCCGCAGAC
GGCTCGGTGCTCGATACGCG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MRATFKYWSLQHAPLQSEAHRNASADARPPEIVGARVWFAGVHRTMNKTPMTLALNGATADHSDTSDLPDATLADSIGAT
STPLDLAAQQAGTQTLLRGLAILEAVAAGARDMRAIGAALGTTRSTTHRLVSSLVQARYLRQVQGGYLLGPKLIELGTIA
LEQMPLTAVARPHLEALAQATLDTIHLGVRDGDDVLYIDKIPGTRGLEMRSRIGHRMPLASTGIGKAMMLDLDPDTWRAL
FDASKRALAGVNFKPDRRPDVGTFLQRMAHYAAGGYTFDLEENETSIRCVAAPVRDASGAIVAALSVASTIPYMSLDRMN
ELVPLVQRGARAISADLGWSAPQATRRIKR

Sequences:

>Translated_350_residues
MRATFKYWSLQHAPLQSEAHRNASADARPPEIVGARVWFAGVHRTMNKTPMTLALNGATADHSDTSDLPDATLADSIGAT
STPLDLAAQQAGTQTLLRGLAILEAVAAGARDMRAIGAALGTTRSTTHRLVSSLVQARYLRQVQGGYLLGPKLIELGTIA
LEQMPLTAVARPHLEALAQATLDTIHLGVRDGDDVLYIDKIPGTRGLEMRSRIGHRMPLASTGIGKAMMLDLDPDTWRAL
FDASKRALAGVNFKPDRRPDVGTFLQRMAHYAAGGYTFDLEENETSIRCVAAPVRDASGAIVAALSVASTIPYMSLDRMN
ELVPLVQRGARAISADLGWSAPQATRRIKR
>Mature_350_residues
MRATFKYWSLQHAPLQSEAHRNASADARPPEIVGARVWFAGVHRTMNKTPMTLALNGATADHSDTSDLPDATLADSIGAT
STPLDLAAQQAGTQTLLRGLAILEAVAAGARDMRAIGAALGTTRSTTHRLVSSLVQARYLRQVQGGYLLGPKLIELGTIA
LEQMPLTAVARPHLEALAQATLDTIHLGVRDGDDVLYIDKIPGTRGLEMRSRIGHRMPLASTGIGKAMMLDLDPDTWRAL
FDASKRALAGVNFKPDRRPDVGTFLQRMAHYAAGGYTFDLEENETSIRCVAAPVRDASGAIVAALSVASTIPYMSLDRMN
ELVPLVQRGARAISADLGWSAPQATRRIKR

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=266, Percent_Identity=33.4586466165414, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1789999, Length=259, Percent_Identity=32.046332046332, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786468, Length=252, Percent_Identity=30.5555555555556, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786715, Length=256, Percent_Identity=27.734375, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082359, Length=252, Percent_Identity=27.7777777777778, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788581, Length=251, Percent_Identity=29.8804780876494, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790752, Length=255, Percent_Identity=24.3137254901961, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 37634; Mature: 37634

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRATFKYWSLQHAPLQSEAHRNASADARPPEIVGARVWFAGVHRTMNKTPMTLALNGATA
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
DHSDTSDLPDATLADSIGATSTPLDLAAQQAGTQTLLRGLAILEAVAAGARDMRAIGAAL
CCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
GTTRSTTHRLVSSLVQARYLRQVQGGYLLGPKLIELGTIALEQMPLTAVARPHLEALAQA
CCCHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TLDTIHLGVRDGDDVLYIDKIPGTRGLEMRSRIGHRMPLASTGIGKAMMLDLDPDTWRAL
HHHHHEEEEECCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHH
FDASKRALAGVNFKPDRRPDVGTFLQRMAHYAAGGYTFDLEENETSIRCVAAPVRDASGA
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEECCCCCCCH
IVAALSVASTIPYMSLDRMNELVPLVQRGARAISADLGWSAPQATRRIKR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
>Mature Secondary Structure
MRATFKYWSLQHAPLQSEAHRNASADARPPEIVGARVWFAGVHRTMNKTPMTLALNGATA
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
DHSDTSDLPDATLADSIGATSTPLDLAAQQAGTQTLLRGLAILEAVAAGARDMRAIGAAL
CCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
GTTRSTTHRLVSSLVQARYLRQVQGGYLLGPKLIELGTIALEQMPLTAVARPHLEALAQA
CCCHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TLDTIHLGVRDGDDVLYIDKIPGTRGLEMRSRIGHRMPLASTGIGKAMMLDLDPDTWRAL
HHHHHEEEEECCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHH
FDASKRALAGVNFKPDRRPDVGTFLQRMAHYAAGGYTFDLEENETSIRCVAAPVRDASGA
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEECCCCCCCH
IVAALSVASTIPYMSLDRMNELVPLVQRGARAISADLGWSAPQATRRIKR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]