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The map label for this gene is kdpE [H]

Identifier: 83719874

GI number: 83719874

Start: 1164867

End: 1165571

Strand: Direct

Name: kdpE [H]

Synonym: BTH_I1025

Alternate gene names: 83719874

Gene position: 1164867-1165571 (Clockwise)

Preceding gene: 83718958

Following gene: 83721241

Centisome position: 30.58

GC content: 69.08

Gene sequence:

>705_bases
ATGCCCATGAGTGAACCGACCGTCACCGTCGTTCTGATCGAAGACGAAAAACAGATCCGCCGTTTCGTGCGCAGCGCGCT
GGAGGAAGAGGGCATCGCGGTATTCGACGCCGAAACGGGCCGCCAGGGCCTCATCGAGGCCGCGACCCGCAAGCCCGACC
TCGCGATCGTCGATCTCGGGCTGCCGGACGGCGACGGCCTCGACGTGATCCGCGAACTGCGCGGCTGGTCCGAAATGCCG
GTGATCGTGCTGTCGGCGCGCACGCACGAGGAGGAGAAGGTGGCCGCGCTCGATGCGGGCGCGGACGACTACCTGACGAA
GCCGTTCGGCGTTTCCGAGCTGCTCGCGCGGATACGCGCGCACCTGCGGCGGCGCAATCAGGGCGGCGCGGCCGAATCGC
CGGTCGTGAAGTTCGGCGACGTGAGCGTCGACCTCGCGCTGCGGCGGGTATGGCGCGGCGGCGAGGTCGTGCATCTGACG
CCGCTCGAGTACCGGCTGCTCGCGACGCTCGTGCGGCACGCGGGCCGCGTGCTCACGCACCGCCAGCTGTTGCGCAACGT
CTGGGGGCCGACACACGTCGAGAGCCACCACTACCTGCGAATCTACATGGCGCATTTGCGGCAAAAGCTCGAGGCTGATC
CCGCGCAGCCGCAGCACATCGTGACCGAGACGGGCGTCGGCTACCGGCTCGTCGGCGCGGGCTGA

Upstream 100 bases:

>100_bases
GCGGACCCTGCCCGCCCGGCGTCCGGCCAAGCCGCTGCGGCGTCTTCCGCGCCGCGCCGCGCCGAGGGAGCGCCGTCGCC
CGTATCCAACGAACATCCGC

Downstream 100 bases:

>100_bases
CGCATGGGGCGGCACCGGCGCGCATTCGGGCGCCGCTGCTCGCGGCGCCTCGTCCGTCGTTCGCCGATCTCCAATTTCCG
CTCGTCATCCGGCAATCGCC

Product: DNA-binding response regulator KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MPMSEPTVTVVLIEDEKQIRRFVRSALEEEGIAVFDAETGRQGLIEAATRKPDLAIVDLGLPDGDGLDVIRELRGWSEMP
VIVLSARTHEEEKVAALDAGADDYLTKPFGVSELLARIRAHLRRRNQGGAAESPVVKFGDVSVDLALRRVWRGGEVVHLT
PLEYRLLATLVRHAGRVLTHRQLLRNVWGPTHVESHHYLRIYMAHLRQKLEADPAQPQHIVTETGVGYRLVGAG

Sequences:

>Translated_234_residues
MPMSEPTVTVVLIEDEKQIRRFVRSALEEEGIAVFDAETGRQGLIEAATRKPDLAIVDLGLPDGDGLDVIRELRGWSEMP
VIVLSARTHEEEKVAALDAGADDYLTKPFGVSELLARIRAHLRRRNQGGAAESPVVKFGDVSVDLALRRVWRGGEVVHLT
PLEYRLLATLVRHAGRVLTHRQLLRNVWGPTHVESHHYLRIYMAHLRQKLEADPAQPQHIVTETGVGYRLVGAG
>Mature_233_residues
PMSEPTVTVVLIEDEKQIRRFVRSALEEEGIAVFDAETGRQGLIEAATRKPDLAIVDLGLPDGDGLDVIRELRGWSEMPV
IVLSARTHEEEKVAALDAGADDYLTKPFGVSELLARIRAHLRRRNQGGAAESPVVKFGDVSVDLALRRVWRGGEVVHLTP
LEYRLLATLVRHAGRVLTHRQLLRNVWGPTHVESHHYLRIYMAHLRQKLEADPAQPQHIVTETGVGYRLVGAG

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=65.0224215246637, Blast_Score=300, Evalue=8e-83,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=38.0090497737557, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=38.3928571428571, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=34.8214285714286, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=33.1914893617021, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=37.0044052863436, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=33.7662337662338, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=35.1111111111111, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=33.1838565022422, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=35.8744394618834, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=30.5676855895196, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=30.8695652173913, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=30.7017543859649, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=28.3842794759825, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=33.9622641509434, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=122, Percent_Identity=31.1475409836066, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26060; Mature: 25929

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMSEPTVTVVLIEDEKQIRRFVRSALEEEGIAVFDAETGRQGLIEAATRKPDLAIVDLG
CCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCCEEEEEEC
LPDGDGLDVIRELRGWSEMPVIVLSARTHEEEKVAALDAGADDYLTKPFGVSELLARIRA
CCCCCCHHHHHHHCCCCCCCEEEEECCCCCHHHHHHCCCCCCHHCCCCCCHHHHHHHHHH
HLRRRNQGGAAESPVVKFGDVSVDLALRRVWRGGEVVHLTPLEYRLLATLVRHAGRVLTH
HHHHCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHH
RQLLRNVWGPTHVESHHYLRIYMAHLRQKLEADPAQPQHIVTETGVGYRLVGAG
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCC
>Mature Secondary Structure 
PMSEPTVTVVLIEDEKQIRRFVRSALEEEGIAVFDAETGRQGLIEAATRKPDLAIVDLG
CCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCCEEEEEEC
LPDGDGLDVIRELRGWSEMPVIVLSARTHEEEKVAALDAGADDYLTKPFGVSELLARIRA
CCCCCCHHHHHHHCCCCCCCEEEEECCCCCHHHHHHCCCCCCHHCCCCCCHHHHHHHHHH
HLRRRNQGGAAESPVVKFGDVSVDLALRRVWRGGEVVHLTPLEYRLLATLVRHAGRVLTH
HHHHCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHH
RQLLRNVWGPTHVESHHYLRIYMAHLRQKLEADPAQPQHIVTETGVGYRLVGAG
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]