Click here to switch to the map view.

The map label for this gene is epsA [H]

Identifier: 83719749

GI number: 83719749

Start: 1529591

End: 1530781

Strand: Direct

Name: epsA [H]

Synonym: BTH_I1352

Alternate gene names: 83719749

Gene position: 1529591-1530781 (Clockwise)

Preceding gene: 83719291

Following gene: 83721645

Centisome position: 40.16

GC content: 70.19

Gene sequence:

>1191_bases
ATGGGTAGTCTGGGGGAAGCTGGCGGCGTCGCGCCGCCGGAACGCACGTACGGCGCGCGCGTGCGTGGGTTGACGAGATG
GGTGCCGCTGTGCGCGGCGCTCGCGACATTGAGTGCGTGCGGCGTCGCGCCGGGCATGCGGATGAAGCAGCCGGCGAGCG
TGCCGGTGTCGGGCGCGCCGGCCGCGGCAGGCGGCGAGTCGCGCGGCGAGCAGTTGCCGGTTCCGATCACGGACATCGAT
CTGAATCTGATCCGCACGCTGCGCGACGCGCAGCGGCTGCCGCGTCGCGCGTCCGATCTCGCGTCGCCGGCGTCCGCCTA
CACGATCGGGCGCGGCGACGTGCTGCAGATCACGGTCTGGGATCATCCCGAGCTTGCGGCGGCGCTCGGCACGCAGCAGC
AGACGGCGGCGCGCGCGGCCGATGCGCCGGCGGGTTTCGTCGTCGATCAGGACGGCACGCTGCAGTTTCCGTACGTCGGG
CGCATCGCTGTTGCCGGGCTCAAGCCCGAGCAGGTGCAGGCGCGACTCGCGCGCAAGCTTGCACAGACGTTTCGCGATCC
GCAGGTGACGGTGCGCATCGCATCGTTTCGCGCGAAGCAGGTCTACATAGAAGGCGAAGTGCGTACGCCCGGCTCGCAGG
CGCTCAACGACATTCCGATGACGCTGTACGATGCGGTGAGCCGCGCGGGCGGCTTTTCGGCGAGCGCGGACCAGAGCCGC
GTGACGCTCGTGCGCGGCGGCGCCGAGCGGCGGATCGATCTGTCGGGCGCCGCGCAAGGGAGCAATCCTTCGCGGCTCGT
TCTCGAGGACGGCGACCTGCTGCGCATCCCGCCGCGCGACGAAAGCGGCGTGTTCGTGATGGGCGAGGTCAACAAGCCCG
TCACCGCGCTGCCGATGCGCAACGGCCGCTTGACGCTGAGCGATGCGCTGTCGCAGGCCGGCAGCCTGAACGCGACGACG
GCAGACGCCGCGCAGCTATACGTGATCCGCGGCTCGCTCGACGCGAAGCCGCACGTCTATCGGCTCGACGCGAGCTCGCC
CGTCGCGATGGTGCTCGCGAACCAGTTCGAGCTGGAGCCGAAGGACATCGTCTATGTCGACGGCAACGGGCTCGTGCGCT
TCAGCCGCGTGCTCAGTCTGTTGCTGCCCGCCGTCAATGCCGGCCTGACCGCGGCGGTCGTGACCAAATGA

Upstream 100 bases:

>100_bases
GTCAATGTCGTCCTGCGCGGATCGGGCGCGTATTGAGCGTGCTTCGTGCGGCGATCGGCGGCCGGAACAGGCCGGAGCTA
GAAAATGGATAGAGGTGTAG

Downstream 100 bases:

>100_bases
TCGACTCGATTCTCGTCGTCTGCGAAGGCAATCTCTGCCGCAGCCCGATGGCGGCCGCGCTCTTCGCGGCGTCGCTGCCT
GGGCGTACGGTGACGTCGGC

Product: capsular polysaccharide biosynthesis/export periplasmic protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MGSLGEAGGVAPPERTYGARVRGLTRWVPLCAALATLSACGVAPGMRMKQPASVPVSGAPAAAGGESRGEQLPVPITDID
LNLIRTLRDAQRLPRRASDLASPASAYTIGRGDVLQITVWDHPELAAALGTQQQTAARAADAPAGFVVDQDGTLQFPYVG
RIAVAGLKPEQVQARLARKLAQTFRDPQVTVRIASFRAKQVYIEGEVRTPGSQALNDIPMTLYDAVSRAGGFSASADQSR
VTLVRGGAERRIDLSGAAQGSNPSRLVLEDGDLLRIPPRDESGVFVMGEVNKPVTALPMRNGRLTLSDALSQAGSLNATT
ADAAQLYVIRGSLDAKPHVYRLDASSPVAMVLANQFELEPKDIVYVDGNGLVRFSRVLSLLLPAVNAGLTAAVVTK

Sequences:

>Translated_396_residues
MGSLGEAGGVAPPERTYGARVRGLTRWVPLCAALATLSACGVAPGMRMKQPASVPVSGAPAAAGGESRGEQLPVPITDID
LNLIRTLRDAQRLPRRASDLASPASAYTIGRGDVLQITVWDHPELAAALGTQQQTAARAADAPAGFVVDQDGTLQFPYVG
RIAVAGLKPEQVQARLARKLAQTFRDPQVTVRIASFRAKQVYIEGEVRTPGSQALNDIPMTLYDAVSRAGGFSASADQSR
VTLVRGGAERRIDLSGAAQGSNPSRLVLEDGDLLRIPPRDESGVFVMGEVNKPVTALPMRNGRLTLSDALSQAGSLNATT
ADAAQLYVIRGSLDAKPHVYRLDASSPVAMVLANQFELEPKDIVYVDGNGLVRFSRVLSLLLPAVNAGLTAAVVTK
>Mature_395_residues
GSLGEAGGVAPPERTYGARVRGLTRWVPLCAALATLSACGVAPGMRMKQPASVPVSGAPAAAGGESRGEQLPVPITDIDL
NLIRTLRDAQRLPRRASDLASPASAYTIGRGDVLQITVWDHPELAAALGTQQQTAARAADAPAGFVVDQDGTLQFPYVGR
IAVAGLKPEQVQARLARKLAQTFRDPQVTVRIASFRAKQVYIEGEVRTPGSQALNDIPMTLYDAVSRAGGFSASADQSRV
TLVRGGAERRIDLSGAAQGSNPSRLVLEDGDLLRIPPRDESGVFVMGEVNKPVTALPMRNGRLTLSDALSQAGSLNATTA
DAAQLYVIRGSLDAKPHVYRLDASSPVAMVLANQFELEPKDIVYVDGNGLVRFSRVLSLLLPAVNAGLTAAVVTK

Specific function: Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1787218, Length=384, Percent_Identity=34.6354166666667, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1788376, Length=370, Percent_Identity=34.5945945945946, Blast_Score=206, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715
- InterPro:   IPR019554 [H]

Pfam domain/function: PF02563 Poly_export; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 41659; Mature: 41528

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSLGEAGGVAPPERTYGARVRGLTRWVPLCAALATLSACGVAPGMRMKQPASVPVSGAP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
AAAGGESRGEQLPVPITDIDLNLIRTLRDAQRLPRRASDLASPASAYTIGRGDVLQITVW
CCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCEEEEEEC
DHPELAAALGTQQQTAARAADAPAGFVVDQDGTLQFPYVGRIAVAGLKPEQVQARLARKL
CCCHHHHHHCCCHHHHHHHCCCCCCEEECCCCCEECCCCCEEEEECCCHHHHHHHHHHHH
AQTFRDPQVTVRIASFRAKQVYIEGEVRTPGSQALNDIPMTLYDAVSRAGGFSASADQSR
HHHHCCCEEEEEEEEECEEEEEEEEEECCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCE
VTLVRGGAERRIDLSGAAQGSNPSRLVLEDGDLLRIPPRDESGVFVMGEVNKPVTALPMR
EEEEECCCCEEEEECCCCCCCCCCEEEEECCCEEECCCCCCCCEEEEECCCCCEEEEECC
NGRLTLSDALSQAGSLNATTADAAQLYVIRGSLDAKPHVYRLDASSPVAMVLANQFELEP
CCEEEHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCCEEEEEEHHCCCCC
KDIVYVDGNGLVRFSRVLSLLLPAVNAGLTAAVVTK
CCEEEECCCCEEHHHHHHHHHHHHHCCCCEEEEEEC
>Mature Secondary Structure 
GSLGEAGGVAPPERTYGARVRGLTRWVPLCAALATLSACGVAPGMRMKQPASVPVSGAP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
AAAGGESRGEQLPVPITDIDLNLIRTLRDAQRLPRRASDLASPASAYTIGRGDVLQITVW
CCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCEEEEEEC
DHPELAAALGTQQQTAARAADAPAGFVVDQDGTLQFPYVGRIAVAGLKPEQVQARLARKL
CCCHHHHHHCCCHHHHHHHCCCCCCEEECCCCCEECCCCCEEEEECCCHHHHHHHHHHHH
AQTFRDPQVTVRIASFRAKQVYIEGEVRTPGSQALNDIPMTLYDAVSRAGGFSASADQSR
HHHHCCCEEEEEEEEECEEEEEEEEEECCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCE
VTLVRGGAERRIDLSGAAQGSNPSRLVLEDGDLLRIPPRDESGVFVMGEVNKPVTALPMR
EEEEECCCCEEEEECCCCCCCCCCEEEEECCCEEECCCCCCCCEEEEECCCCCEEEEECC
NGRLTLSDALSQAGSLNATTADAAQLYVIRGSLDAKPHVYRLDASSPVAMVLANQFELEP
CCEEEHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCCEEEEEEHHCCCCC
KDIVYVDGNGLVRFSRVLSLLLPAVNAGLTAAVVTK
CCEEEECCCCEEHHHHHHHHHHHHHCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]