Click here to switch to the map view.

The map label for this gene is blh [H]

Identifier: 83719678

GI number: 83719678

Start: 2569015

End: 2570685

Strand: Reverse

Name: blh [H]

Synonym: BTH_I2281

Alternate gene names: 83719678

Gene position: 2570685-2569015 (Counterclockwise)

Preceding gene: 83721139

Following gene: 83719558

Centisome position: 67.49

GC content: 70.08

Gene sequence:

>1671_bases
ATGGAAATCCGCAAGCTGACCGACACGCTGTCGGTCTCCCCCCAACTCGCCGCCGCCGACCTGCCCGCGATCGCGCAGGC
CGGCTTTCGCGCGATCGTCTGCAACCGGCCGGACGGCGAAGGCCCGGACCAGCCGACTGTCGCCGAGATCGACGCGGCCG
CGAAGCCGTTCGGCATCGCGGTTCACTACCTGCCCGTCGATTCGGGCAAGGTCACCGATTCGCAAGGCGAGCAGTTCGGC
GCACTGCTCGGCACGCTCGCATCGCCCGTGCTCGCGTACTGTCGCACCGGCATGCGCTCGGCGACGTTGTGGGGGCTGTC
GCAGGCGGGGCTGCGGCCGCTGAACGACATCGTCGCCACGGGCCGCGCGGCCGGCTACGATCTCGCCGCGCTCGGCCGCC
GGATCATGCAGCGCAGCCAGAGCGCGGCGACGCAAACCGTCGAGGCGAGCCACGACATCGTGATCGTCGGCGCGGGCGCG
GCGGGGATCGCGATCGCGTCGAGCCTGCTCGCGCGCGATCGCTCGCTCGACATCGCCGTCATCGATCCGGCCGACACCCA
TTACTACCAGCCCGGCTGGACGATGGTCGGCGCGGGCGTGTTCCAGCCGAAGACGACCGCGCGGCAGATGGCTGCCGTGC
TGCCGCGCGGCGTGCACTGGATCAAGGCCGCCGTCGCCGCGTTCGAGCCGGACACGCACACGGTCGTGCTCGACGGCTGC
CGGCTCGTGCGCTACCGGCAGCTCGTCGTCTGCCCGGGGCTGAAGCTCGACTGGCACGGCATCGAAGGGCTGCCCGAGAC
GCTCGGCAAGAACGGCGTCACGTCGAACTACCGCTACGATCTCGCGCCGTACACGTGGCAGCTCGTGCGCACGTTCGCCG
GCCGCCGCGCGCTGTTCACGCAGCCGCCGATGCCGATCAAGTGCGCGGGCGCGCCGCAAAAGGCGATGTATCTGTCTGCC
GACCACTGGCGGCGCACGCATCGTCTCGAGAAGATCGACGTCGAGTTCTTCAACGCGGGCGCGGCGCTCTTTGGCGTCGC
CGATTACGTGCCCGCGCTGATGGAATACGTGAAGCGCTACGACATCGCGCTGAATTTCGGCCACAACCTGATCGCGATCG
ATGGCGAGCGCAAGCGCGCGACGTTCTCCCGCACGTTGCCGGAAGGCGGCGCCGAAACCGTCACGCGCGAATTCGACATG
ATCCACGTCGTGCCGCCGCAGAAGGCGCCCGATTTCGTGCGCGCGAGCCCGCTCGCCGACGCGGCCGGCTGGATCGACGT
CGATCCGGCGACGCTGCGCCACAAGCGCCACGCGGACGTGTTCGCGCTCGGCGACGTGACGAACACGACGAACGCGAAAA
CCGCGGCCGCCGCGCGCAAGCAGGCGCCCGTCGTCGCGCACAACGTGCTCGCCGCGCTCGGCAAGACCCACGGCGACGCG
ACCTACGACGGCTACGGCTCGTGCCCGCTCACCGTCGAGCGCGGCAAGATCGTGCTCGCCGAATTCCTGTACGGCGGCAA
GGTCGCGCCGACCTTCCCCGCGTGGCTCATCGACGGCAAACGCCCGTCGCGGCTCGCGTGGCTGCTCAAGGAGCGGCTGC
TGCCGCCCCTTTACTGGCAGGCGATGCTCAAGGGCCGCGAATGGCTCGCGAAGCCCGAGATCGTCGGCTGA

Upstream 100 bases:

>100_bases
CCCGAGGACAACGGCGTGCGCTACCTGAAGATCCCGCTCGACGCGATCTGAGCGTGCCCGCCCTCCCCAACGACGACACG
ACACACACAACAGGCCAACC

Downstream 100 bases:

>100_bases
TCGCCGCCCATCGATGACCCTCGTCCGGAACAACGAAGCATGCTGATTTCTCTGGTGTTGGGCAGCATCGTCGGCGCGGT
GCTGGGATTGACGGGGGCGG

Product: pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MEIRKLTDTLSVSPQLAAADLPAIAQAGFRAIVCNRPDGEGPDQPTVAEIDAAAKPFGIAVHYLPVDSGKVTDSQGEQFG
ALLGTLASPVLAYCRTGMRSATLWGLSQAGLRPLNDIVATGRAAGYDLAALGRRIMQRSQSAATQTVEASHDIVIVGAGA
AGIAIASSLLARDRSLDIAVIDPADTHYYQPGWTMVGAGVFQPKTTARQMAAVLPRGVHWIKAAVAAFEPDTHTVVLDGC
RLVRYRQLVVCPGLKLDWHGIEGLPETLGKNGVTSNYRYDLAPYTWQLVRTFAGRRALFTQPPMPIKCAGAPQKAMYLSA
DHWRRTHRLEKIDVEFFNAGAALFGVADYVPALMEYVKRYDIALNFGHNLIAIDGERKRATFSRTLPEGGAETVTREFDM
IHVVPPQKAPDFVRASPLADAAGWIDVDPATLRHKRHADVFALGDVTNTTNAKTAAAARKQAPVVAHNVLAALGKTHGDA
TYDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLIDGKRPSRLAWLLKERLLPPLYWQAMLKGREWLAKPEIVG

Sequences:

>Translated_556_residues
MEIRKLTDTLSVSPQLAAADLPAIAQAGFRAIVCNRPDGEGPDQPTVAEIDAAAKPFGIAVHYLPVDSGKVTDSQGEQFG
ALLGTLASPVLAYCRTGMRSATLWGLSQAGLRPLNDIVATGRAAGYDLAALGRRIMQRSQSAATQTVEASHDIVIVGAGA
AGIAIASSLLARDRSLDIAVIDPADTHYYQPGWTMVGAGVFQPKTTARQMAAVLPRGVHWIKAAVAAFEPDTHTVVLDGC
RLVRYRQLVVCPGLKLDWHGIEGLPETLGKNGVTSNYRYDLAPYTWQLVRTFAGRRALFTQPPMPIKCAGAPQKAMYLSA
DHWRRTHRLEKIDVEFFNAGAALFGVADYVPALMEYVKRYDIALNFGHNLIAIDGERKRATFSRTLPEGGAETVTREFDM
IHVVPPQKAPDFVRASPLADAAGWIDVDPATLRHKRHADVFALGDVTNTTNAKTAAAARKQAPVVAHNVLAALGKTHGDA
TYDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLIDGKRPSRLAWLLKERLLPPLYWQAMLKGREWLAKPEIVG
>Mature_556_residues
MEIRKLTDTLSVSPQLAAADLPAIAQAGFRAIVCNRPDGEGPDQPTVAEIDAAAKPFGIAVHYLPVDSGKVTDSQGEQFG
ALLGTLASPVLAYCRTGMRSATLWGLSQAGLRPLNDIVATGRAAGYDLAALGRRIMQRSQSAATQTVEASHDIVIVGAGA
AGIAIASSLLARDRSLDIAVIDPADTHYYQPGWTMVGAGVFQPKTTARQMAAVLPRGVHWIKAAVAAFEPDTHTVVLDGC
RLVRYRQLVVCPGLKLDWHGIEGLPETLGKNGVTSNYRYDLAPYTWQLVRTFAGRRALFTQPPMPIKCAGAPQKAMYLSA
DHWRRTHRLEKIDVEFFNAGAALFGVADYVPALMEYVKRYDIALNFGHNLIAIDGERKRATFSRTLPEGGAETVTREFDM
IHVVPPQKAPDFVRASPLADAAGWIDVDPATLRHKRHADVFALGDVTNTTNAKTAAAARKQAPVVAHNVLAALGKTHGDA
TYDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLIDGKRPSRLAWLLKERLLPPLYWQAMLKGREWLAKPEIVG

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI10864011, Length=406, Percent_Identity=36.6995073891626, Blast_Score=305, Evalue=6e-83,
Organism=Caenorhabditis elegans, GI17539680, Length=421, Percent_Identity=30.6413301662708, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI115534373, Length=343, Percent_Identity=35.5685131195335, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24657386, Length=386, Percent_Identity=37.3056994818653, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24657391, Length=386, Percent_Identity=37.3056994818653, Blast_Score=258, Evalue=6e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 60151; Mature: 60151

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRKLTDTLSVSPQLAAADLPAIAQAGFRAIVCNRPDGEGPDQPTVAEIDAAAKPFGIA
CCHHHHHHHHCCCCCHHHCCCCHHHHCCCEEEEEECCCCCCCCCCCHHHHHCCCCCCEEE
VHYLPVDSGKVTDSQGEQFGALLGTLASPVLAYCRTGMRSATLWGLSQAGLRPLNDIVAT
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHCCCHHHHHHHC
GRAAGYDLAALGRRIMQRSQSAATQTVEASHDIVIVGAGAAGIAIASSLLARDRSLDIAV
CCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCHHHHHHHHHHHHCCCCCEEEE
IDPADTHYYQPGWTMVGAGVFQPKTTARQMAAVLPRGVHWIKAAVAAFEPDTHTVVLDGC
ECCCCCCEECCCCEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEECCH
RLVRYRQLVVCPGLKLDWHGIEGLPETLGKNGVTSNYRYDLAPYTWQLVRTFAGRRALFT
HHHHHHHEEECCCCEEECCCCCCCHHHHCCCCCCCCCEECCCHHHHHHHHHHHCCCEEEC
QPPMPIKCAGAPQKAMYLSADHWRRTHRLEKIDVEFFNAGAALFGVADYVPALMEYVKRY
CCCCCEEECCCCCCEEEEEHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
DIALNFGHNLIAIDGERKRATFSRTLPEGGAETVTREFDMIHVVPPQKAPDFVRASPLAD
CEEEECCCEEEEECCCCCHHHHHHCCCCCCHHHHHCCCCEEEEECCCCCCCCHHCCCCCC
AAGWIDVDPATLRHKRHADVFALGDVTNTTNAKTAAAARKQAPVVAHNVLAALGKTHGDA
CCCEEECCHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCC
TYDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLIDGKRPSRLAWLLKERLLPPLYWQ
CCCCCCCCCEEEECCCEEEEEHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCHHHHH
AMLKGREWLAKPEIVG
HHHHCHHHCCCCCCCC
>Mature Secondary Structure
MEIRKLTDTLSVSPQLAAADLPAIAQAGFRAIVCNRPDGEGPDQPTVAEIDAAAKPFGIA
CCHHHHHHHHCCCCCHHHCCCCHHHHCCCEEEEEECCCCCCCCCCCHHHHHCCCCCCEEE
VHYLPVDSGKVTDSQGEQFGALLGTLASPVLAYCRTGMRSATLWGLSQAGLRPLNDIVAT
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHCCCHHHHHHHC
GRAAGYDLAALGRRIMQRSQSAATQTVEASHDIVIVGAGAAGIAIASSLLARDRSLDIAV
CCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCHHHHHHHHHHHHCCCCCEEEE
IDPADTHYYQPGWTMVGAGVFQPKTTARQMAAVLPRGVHWIKAAVAAFEPDTHTVVLDGC
ECCCCCCEECCCCEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEECCH
RLVRYRQLVVCPGLKLDWHGIEGLPETLGKNGVTSNYRYDLAPYTWQLVRTFAGRRALFT
HHHHHHHEEECCCCEEECCCCCCCHHHHCCCCCCCCCEECCCHHHHHHHHHHHCCCEEEC
QPPMPIKCAGAPQKAMYLSADHWRRTHRLEKIDVEFFNAGAALFGVADYVPALMEYVKRY
CCCCCEEECCCCCCEEEEEHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
DIALNFGHNLIAIDGERKRATFSRTLPEGGAETVTREFDMIHVVPPQKAPDFVRASPLAD
CEEEECCCEEEEECCCCCHHHHHHCCCCCCHHHHHCCCCEEEEECCCCCCCCHHCCCCCC
AAGWIDVDPATLRHKRHADVFALGDVTNTTNAKTAAAARKQAPVVAHNVLAALGKTHGDA
CCCEEECCHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCC
TYDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLIDGKRPSRLAWLLKERLLPPLYWQ
CCCCCCCCCEEEECCCEEEEEHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCHHHHH
AMLKGREWLAKPEIVG
HHHHCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]