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The map label for this gene is fabF [H]

Identifier: 83719581

GI number: 83719581

Start: 1929655

End: 1930920

Strand: Direct

Name: fabF [H]

Synonym: BTH_I1721

Alternate gene names: 83719581

Gene position: 1929655-1930920 (Clockwise)

Preceding gene: 83719572

Following gene: 83719662

Centisome position: 50.66

GC content: 64.61

Gene sequence:

>1266_bases
TTGTCATTCAATGGAAAAGAGGTTACCGTGAGCCGCCGTCGTGTTGTTGTTACAGGCCTTGGGCTGATTTCGCCTGTTGG
CAATAATGTTGCCGACGGCTGGGCCAATCTCGTGGCCGGCAAGTCCGGCATCGTCAATATCACGAAGTTCGACGCGACGA
ACTTCTCGACCCGCTTCGCAGGCGAGGTGAAGGGCTTCAACGTCGAGGATTACATCCCGGCGAAGGAAGCGCGCCACATG
GATACGTTCATCCATTACGGGATCGCGGCCGGCATGCAGGCGATGCAGGACAGCGGCTTCCAGGTCACCGACGAAAACGC
GGAGCGCGTCGGCGTCGTGGTCGGCTCGGGCATCGGCGGGCTGCCGATGATCGAGGTCACGCAGACCGAGCTGCTTAACC
GCGGCCCGCGCCGGATCTCGCCGTTCTTCGTGCCGGCGTCGATCATCAATATGGTGTCCGGCCATCTGTCGATCAAGTTC
GGCATCAAGGGCCCGAATCTGGCGATCGTCACCGCTTGCACGACCGGCCTGCACTGCATCGGCGAAGCTGCGCGCCTCAT
CGAATACGGCGACGCGGACGTGATGATCGCGGGCGGCGCGGAGGCGACGGTGTCGCCGCTCGGCATCGGCGGCTTCGCGG
CGGCGCGCGCGCTGTCGCAGCGCAACGACGATCCGGCGACCGCGAGCCGCCCGTGGGACAAGGACCGCGACGGCTTCGTG
CTCGGCGAAGGCGCGGGCGTGATGGTGCTCGAGGAGTACGAGCACGCGAAGGCGCGGGGCGCGAAGATCTACGCGGAAAT
CGGGGGCTACGGGATGAGCGGCGACGCGTATCACATGACGGCTCCGCTCGAGGATGGCGACGGTGCGCGACGCTGCATGC
TGGCCGCGCTGCGCAACGCCGGCATCAACGTCGATCAGGTCAACTACCTGAACGCGCACGGCACGTCGACGCCGCTTGGC
GACGTCGCGGAAACGGTCGCGATCAAGCGGGCGTTCGGCGATCACGCGAAGCAAATCGTCGTCAACTCGACGAAGTCGAT
GACGGGCCACCTGCTCGGCGGGTCGGGCGGGCTCGAATCGGTGTTCACGGTCCTCGCCGTCCACAACCAGGTGTCGCCGC
CGACGATCAACATCTTCAACCAGGATCCCGCGTGCGATCTGGATTATTGCGCGAACGAAGCGCGCGAGATGAAGATCGAT
GTCGCGTTGAAGAACTCCTTCGGCTTCGGCGGGACTAACGGCACGCTGGTCTTCAAGCGCGTCTGA

Upstream 100 bases:

>100_bases
CGCTGCGCCGGATGCGCGATCGCGTCGGCGTTCTCGCCGGCCGAGCTAACAGCCACAGGGCTCGCAGGGGTGGTTCCTGT
GGCCGCTGTGGCTTTTGTTT

Downstream 100 bases:

>100_bases
TGCGGGGTCGCTTGACGGAGCCGTTCCACGCCATGTCGGCAGGCGCGCAGCACGTCGTGCTGCGCGCGTCGGCGCGGCTG
CGCGCCGCGTGCGCGCTGTT

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MSFNGKEVTVSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIVNITKFDATNFSTRFAGEVKGFNVEDYIPAKEARHM
DTFIHYGIAAGMQAMQDSGFQVTDENAERVGVVVGSGIGGLPMIEVTQTELLNRGPRRISPFFVPASIINMVSGHLSIKF
GIKGPNLAIVTACTTGLHCIGEAARLIEYGDADVMIAGGAEATVSPLGIGGFAAARALSQRNDDPATASRPWDKDRDGFV
LGEGAGVMVLEEYEHAKARGAKIYAEIGGYGMSGDAYHMTAPLEDGDGARRCMLAALRNAGINVDQVNYLNAHGTSTPLG
DVAETVAIKRAFGDHAKQIVVNSTKSMTGHLLGGSGGLESVFTVLAVHNQVSPPTINIFNQDPACDLDYCANEAREMKID
VALKNSFGFGGTNGTLVFKRV

Sequences:

>Translated_421_residues
MSFNGKEVTVSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIVNITKFDATNFSTRFAGEVKGFNVEDYIPAKEARHM
DTFIHYGIAAGMQAMQDSGFQVTDENAERVGVVVGSGIGGLPMIEVTQTELLNRGPRRISPFFVPASIINMVSGHLSIKF
GIKGPNLAIVTACTTGLHCIGEAARLIEYGDADVMIAGGAEATVSPLGIGGFAAARALSQRNDDPATASRPWDKDRDGFV
LGEGAGVMVLEEYEHAKARGAKIYAEIGGYGMSGDAYHMTAPLEDGDGARRCMLAALRNAGINVDQVNYLNAHGTSTPLG
DVAETVAIKRAFGDHAKQIVVNSTKSMTGHLLGGSGGLESVFTVLAVHNQVSPPTINIFNQDPACDLDYCANEAREMKID
VALKNSFGFGGTNGTLVFKRV
>Mature_420_residues
SFNGKEVTVSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIVNITKFDATNFSTRFAGEVKGFNVEDYIPAKEARHMD
TFIHYGIAAGMQAMQDSGFQVTDENAERVGVVVGSGIGGLPMIEVTQTELLNRGPRRISPFFVPASIINMVSGHLSIKFG
IKGPNLAIVTACTTGLHCIGEAARLIEYGDADVMIAGGAEATVSPLGIGGFAAARALSQRNDDPATASRPWDKDRDGFVL
GEGAGVMVLEEYEHAKARGAKIYAEIGGYGMSGDAYHMTAPLEDGDGARRCMLAALRNAGINVDQVNYLNAHGTSTPLGD
VAETVAIKRAFGDHAKQIVVNSTKSMTGHLLGGSGGLESVFTVLAVHNQVSPPTINIFNQDPACDLDYCANEAREMKIDV
ALKNSFGFGGTNGTLVFKRV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=423, Percent_Identity=47.2813238770686, Blast_Score=385, Evalue=1e-107,
Organism=Homo sapiens, GI223972627, Length=147, Percent_Identity=53.0612244897959, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI41872631, Length=427, Percent_Identity=24.3559718969555, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1787337, Length=413, Percent_Identity=62.227602905569, Blast_Score=514, Evalue=1e-147,
Organism=Escherichia coli, GI1788663, Length=414, Percent_Identity=39.8550724637681, Blast_Score=265, Evalue=4e-72,
Organism=Caenorhabditis elegans, GI71983541, Length=413, Percent_Identity=36.5617433414044, Blast_Score=251, Evalue=7e-67,
Organism=Caenorhabditis elegans, GI71983535, Length=255, Percent_Identity=40.7843137254902, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI212642053, Length=424, Percent_Identity=25, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=412, Percent_Identity=23.7864077669903, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320904, Length=447, Percent_Identity=35.5704697986577, Blast_Score=275, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24644341, Length=418, Percent_Identity=46.1722488038278, Blast_Score=359, Evalue=2e-99,
Organism=Drosophila melanogaster, GI221330659, Length=382, Percent_Identity=25.6544502617801, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI19920632, Length=382, Percent_Identity=25.6544502617801, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24581345, Length=427, Percent_Identity=23.1850117096019, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44383; Mature: 44252

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNGKEVTVSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIVNITKFDATNFSTRFA
CCCCCCEEEEECCEEEEEECCHHCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCEEC
GEVKGFNVEDYIPAKEARHMDTFIHYGIAAGMQAMQDSGFQVTDENAERVGVVVGSGIGG
CCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEECCCCC
LPMIEVTQTELLNRGPRRISPFFVPASIINMVSGHLSIKFGIKGPNLAIVTACTTGLHCI
CCEEEEHHHHHHCCCCCCCCCEEEHHHHHHHHCCCEEEEEECCCCCEEEEEEEHHHHHHH
GEAARLIEYGDADVMIAGGAEATVSPLGIGGFAAARALSQRNDDPATASRPWDKDRDGFV
HHHHHHHEECCCCEEEECCCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
LGEGAGVMVLEEYEHAKARGAKIYAEIGGYGMSGDAYHMTAPLEDGDGARRCMLAALRNA
EECCCCEEEEECCHHHHHCCCEEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHC
GINVDQVNYLNAHGTSTPLGDVAETVAIKRAFGDHAKQIVVNSTKSMTGHLLGGSGGLES
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEECCCCCHHH
VFTVLAVHNQVSPPTINIFNQDPACDLDYCANEAREMKIDVALKNSFGFGGTNGTLVFKR
HHHHHHHHCCCCCCEEEEECCCCCCCHHHHCCCCCEEEEEEEEECCCCCCCCCCEEEEEE
V
C
>Mature Secondary Structure 
SFNGKEVTVSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIVNITKFDATNFSTRFA
CCCCCEEEEECCEEEEEECCHHCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCEEC
GEVKGFNVEDYIPAKEARHMDTFIHYGIAAGMQAMQDSGFQVTDENAERVGVVVGSGIGG
CCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEECCCCC
LPMIEVTQTELLNRGPRRISPFFVPASIINMVSGHLSIKFGIKGPNLAIVTACTTGLHCI
CCEEEEHHHHHHCCCCCCCCCEEEHHHHHHHHCCCEEEEEECCCCCEEEEEEEHHHHHHH
GEAARLIEYGDADVMIAGGAEATVSPLGIGGFAAARALSQRNDDPATASRPWDKDRDGFV
HHHHHHHEECCCCEEEECCCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
LGEGAGVMVLEEYEHAKARGAKIYAEIGGYGMSGDAYHMTAPLEDGDGARRCMLAALRNA
EECCCCEEEEECCHHHHHCCCEEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHC
GINVDQVNYLNAHGTSTPLGDVAETVAIKRAFGDHAKQIVVNSTKSMTGHLLGGSGGLES
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEECCCCCHHH
VFTVLAVHNQVSPPTINIFNQDPACDLDYCANEAREMKIDVALKNSFGFGGTNGTLVFKR
HHHHHHHHCCCCCCEEEEECCCCCCCHHHHCCCCCEEEEEEEEECCCCCCCCCCEEEEEE
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]