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The map label for this gene is pucD [H]

Identifier: 83719457

GI number: 83719457

Start: 1587396

End: 1589759

Strand: Direct

Name: pucD [H]

Synonym: BTH_I1409

Alternate gene names: 83719457

Gene position: 1587396-1589759 (Clockwise)

Preceding gene: 83721662

Following gene: 83720611

Centisome position: 41.67

GC content: 69.88

Gene sequence:

>2364_bases
ATGAATCAGCAAGCCGAACCTTTCCTGAGCGTCGCAGCGAACGCCGAGCGCGACGCGTTCAAGCAAGTCCACGTGTCGCG
TCCGCATGAATCCGCGCATCTGCACGTGAGCGGACGCGCGACCTACACCGACGACATCCCGCTCGTCGCCGGCACGCTGC
ACGCGGCGCTCGGCCTGTCCGCGAAGCCGCACGCGAGGATCGCGTCGATGCGGCTCGACGCGGTGCGCGCGGCGGCGGGC
GTCGTCGCGGTGCTGACCGCGGCCGACATTCCGGGCGCGAACGATTGCGGGCCGATCGTCCATGACGATCCGGTGCTCGC
CGACGGCGTCGTTCAGTACGTCGGGCAGCCGATGTTCGTCGTCGTCGCGGCGTCGCACGACGCCGCGCGCCGCGCCGCGC
GCCTCGCGCAGATCGAATACGAAGCGTTGCCGGCGATCCTGACCGCGCAGGCGGCGCGCGCGGCCGATTCGTACGTGCTG
CCGCCGATGACGCTCGCGCGCGGCGACGCGGCCGAACGGATCGCGCGCGCCGTGCATCGCGACGCGGGCGAGCTGACGCT
CGGCGGGCAGGAGCAGTTCTATCTCGAAGGGCAGATCGCCTACGCGGTGCCGAAAGAAGACGGCGCGATGCACGTGTACA
GCTCGACGCAGCATCCGAGCGAGATGCAGCACCTCGTCGCGCACGTGCTGGGGCTCGCGTCGCACGACGTGCTCGTCGAA
TGCCGGCGCATGGGCGGCGGCTTCGGCGGCAAGGAATCGCAATCGGGCCTGTTCGCGTGCTGCGCCGCGCTCGCCGCCTG
GAAGCTGCAGTGCCCGGTGAAGCTGCGCCCCGATCGCGACGACGACATGATGATCACCGGCAAGCGGCACGATTTCCATT
ATCGCTACGACGTCGGCTACGACGACGCGGGCGTGATCGAGGGCGTCTCGGTCGACATGACGTCGCGCTGCGGCTTTTCC
GCCGATCTGTCGGGGCCCGTGATGACGCGCGCCGTGTGCCACTTCGACAACGCGTACTGGCTGCCCGACGTGTCGATCGT
CGGCCGATGCGGGAAGACGAACACGCAGTCGAACACCGCGTTTCGCGGCTTCGGCGGCCCGCAGGGCGCGTTCGCGATCG
AGTACATCATCGACAGCGTCGCGCGCGCGCTCGGCCGCGATCCGCTCGACGTGCGCCGCGCGAACCTGTACGGCAAGACC
GAGCGCAACGTGACGCCCTACGGGCAGACGATCGAGGACAACGTGCTGCCCGAGCTGATCGCCGAGCTCGAGGCGACGAG
CGCGTATCGCGCGCGCCGCGCGGCGACGCGCGCGTTCAACGCGGCGAGCCCGGTGCTGAAGAAGGGCATCGCGCTCACGC
CGGTGAAGTTCGGCATCGCGTTCAACGTCACGCATTTCAACCAGGCGGGCGCGCTCGTCCACATCTACACCGACGGCTCG
ATCCTCGTGAACCACGGCGGCACCGAGATGGGCCAGGGGCTCAACACGAAGGTCGCGCAGGTCGTCGCGCACGAACTCGG
CGTGGACTTCGCGCGGATTCGCGTGACGGCGACCGACACGAGCAAGGTCGCGAACACGTCGGCGACGGCGGCGTCGACGG
GCTCGGACCTGAACGGCAAGGCCGCGCAGGACGCCGCGCGCCAGTTGCGCGAGCGGCTTGCCGCGTTCGCGGCCGAGCAT
TTCGGCGGCGGCAACGCGCGAGCGGCGGACGTGCGCTTCGCGCGCGACGAGGTGCGCGTCGGCGAGACGGCCGTGCCGTT
CGAGGCGCTCGCCGCGCAGGCGTATCGCGCGCGCGTGCAGCTGTGGTCGGACGGCTTCTATGCGACGCCGAAGCTGCACT
GGGATCAGGCGACGCTGCGCGGGCGGCCGTTCTTCTACTACGCGTACGGCGCGGCGGTGTCGGAAGTCGTCGTCGATACG
CTGACGGGCGAGATGCGCGTGTTGCGCGCGGATGCGCTGCATGACGTCGGCGCGTCGCTGAATCCGGCGCTCGACATCGG
GCAGGTCGAGGGCGCGTTCATCCAGGGGATGGGGTGGCTCACGACCGAGGAATTGTGGTGGAACGATGGCGGCAAGCTGA
TGACGCACGCACCGTCGACCTACAAGATTCCGACCGTCAACGATTGTCCGCCGGATTTCCGCGTGAAGCTGTTCGACAAC
CGCAACGCGGAGGACAGCATTCACCGGTCGAAGGCCGTCGGCGAGCCGCCGCTGTTGCTGCCGTTCTCGGTGTTCTTCGC
GATCCGCGACGCGGTTGCGGCGGTGGGCGATTACGCGATCAATCCGCCGCTCGCCGCGCCCGCGACGGGCGAGTCGATCC
TGCGCGCGGTGCAGGCGGTGCGCGCCGCGCGGGCGGGCGCGTGA

Upstream 100 bases:

>100_bases
CCCGCTCGATCCGCTGCCCGCGTCGGCCGTGAACGTGCGCGAAGTCGCCGCCGAGCCGGCCGCTTCCTGACCGATCGACG
CCCAGCGGAGCCATCGCATC

Downstream 100 bases:

>100_bases
TGCGGGGCGGGGGCGCGGCGGAGGGCGTGGGCGGCGCGCGTCGGCGCATGCGGCAAGCACGGTCAGCAGGGAAAGCGCGA
CAGCCGCAAGGCTTAGGAGA

Product: xanthine dehydrogenase, C-terminal subunit

Products: NA

Alternate protein names: XDHase subunit D [H]

Number of amino acids: Translated: 787; Mature: 787

Protein sequence:

>787_residues
MNQQAEPFLSVAANAERDAFKQVHVSRPHESAHLHVSGRATYTDDIPLVAGTLHAALGLSAKPHARIASMRLDAVRAAAG
VVAVLTAADIPGANDCGPIVHDDPVLADGVVQYVGQPMFVVVAASHDAARRAARLAQIEYEALPAILTAQAARAADSYVL
PPMTLARGDAAERIARAVHRDAGELTLGGQEQFYLEGQIAYAVPKEDGAMHVYSSTQHPSEMQHLVAHVLGLASHDVLVE
CRRMGGGFGGKESQSGLFACCAALAAWKLQCPVKLRPDRDDDMMITGKRHDFHYRYDVGYDDAGVIEGVSVDMTSRCGFS
ADLSGPVMTRAVCHFDNAYWLPDVSIVGRCGKTNTQSNTAFRGFGGPQGAFAIEYIIDSVARALGRDPLDVRRANLYGKT
ERNVTPYGQTIEDNVLPELIAELEATSAYRARRAATRAFNAASPVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGS
ILVNHGGTEMGQGLNTKVAQVVAHELGVDFARIRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAAFAAEH
FGGGNARAADVRFARDEVRVGETAVPFEALAAQAYRARVQLWSDGFYATPKLHWDQATLRGRPFFYYAYGAAVSEVVVDT
LTGEMRVLRADALHDVGASLNPALDIGQVEGAFIQGMGWLTTEELWWNDGGKLMTHAPSTYKIPTVNDCPPDFRVKLFDN
RNAEDSIHRSKAVGEPPLLLPFSVFFAIRDAVAAVGDYAINPPLAAPATGESILRAVQAVRAARAGA

Sequences:

>Translated_787_residues
MNQQAEPFLSVAANAERDAFKQVHVSRPHESAHLHVSGRATYTDDIPLVAGTLHAALGLSAKPHARIASMRLDAVRAAAG
VVAVLTAADIPGANDCGPIVHDDPVLADGVVQYVGQPMFVVVAASHDAARRAARLAQIEYEALPAILTAQAARAADSYVL
PPMTLARGDAAERIARAVHRDAGELTLGGQEQFYLEGQIAYAVPKEDGAMHVYSSTQHPSEMQHLVAHVLGLASHDVLVE
CRRMGGGFGGKESQSGLFACCAALAAWKLQCPVKLRPDRDDDMMITGKRHDFHYRYDVGYDDAGVIEGVSVDMTSRCGFS
ADLSGPVMTRAVCHFDNAYWLPDVSIVGRCGKTNTQSNTAFRGFGGPQGAFAIEYIIDSVARALGRDPLDVRRANLYGKT
ERNVTPYGQTIEDNVLPELIAELEATSAYRARRAATRAFNAASPVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGS
ILVNHGGTEMGQGLNTKVAQVVAHELGVDFARIRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAAFAAEH
FGGGNARAADVRFARDEVRVGETAVPFEALAAQAYRARVQLWSDGFYATPKLHWDQATLRGRPFFYYAYGAAVSEVVVDT
LTGEMRVLRADALHDVGASLNPALDIGQVEGAFIQGMGWLTTEELWWNDGGKLMTHAPSTYKIPTVNDCPPDFRVKLFDN
RNAEDSIHRSKAVGEPPLLLPFSVFFAIRDAVAAVGDYAINPPLAAPATGESILRAVQAVRAARAGA
>Mature_787_residues
MNQQAEPFLSVAANAERDAFKQVHVSRPHESAHLHVSGRATYTDDIPLVAGTLHAALGLSAKPHARIASMRLDAVRAAAG
VVAVLTAADIPGANDCGPIVHDDPVLADGVVQYVGQPMFVVVAASHDAARRAARLAQIEYEALPAILTAQAARAADSYVL
PPMTLARGDAAERIARAVHRDAGELTLGGQEQFYLEGQIAYAVPKEDGAMHVYSSTQHPSEMQHLVAHVLGLASHDVLVE
CRRMGGGFGGKESQSGLFACCAALAAWKLQCPVKLRPDRDDDMMITGKRHDFHYRYDVGYDDAGVIEGVSVDMTSRCGFS
ADLSGPVMTRAVCHFDNAYWLPDVSIVGRCGKTNTQSNTAFRGFGGPQGAFAIEYIIDSVARALGRDPLDVRRANLYGKT
ERNVTPYGQTIEDNVLPELIAELEATSAYRARRAATRAFNAASPVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGS
ILVNHGGTEMGQGLNTKVAQVVAHELGVDFARIRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAAFAAEH
FGGGNARAADVRFARDEVRVGETAVPFEALAAQAYRARVQLWSDGFYATPKLHWDQATLRGRPFFYYAYGAAVSEVVVDT
LTGEMRVLRADALHDVGASLNPALDIGQVEGAFIQGMGWLTTEELWWNDGGKLMTHAPSTYKIPTVNDCPPDFRVKLFDN
RNAEDSIHRSKAVGEPPLLLPFSVFFAIRDAVAAVGDYAINPPLAAPATGESILRAVQAVRAARAGA

Specific function: Oxidizes hypoxanthine and xanthine to uric acid [H]

COG id: COG4631

COG function: function code F; Xanthine dehydrogenase, molybdopterin-binding subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=728, Percent_Identity=43.1318681318681, Blast_Score=581, Evalue=1e-166,
Organism=Homo sapiens, GI71773480, Length=757, Percent_Identity=37.78071334214, Blast_Score=464, Evalue=1e-130,
Organism=Escherichia coli, GI1789230, Length=760, Percent_Identity=29.2105263157895, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI1789246, Length=776, Percent_Identity=26.0309278350515, Blast_Score=185, Evalue=1e-47,
Organism=Escherichia coli, GI1786478, Length=734, Percent_Identity=25.4768392370572, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=770, Percent_Identity=39.4805194805195, Blast_Score=499, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI32566215, Length=708, Percent_Identity=31.638418079096, Blast_Score=325, Evalue=6e-89,
Organism=Caenorhabditis elegans, GI17539860, Length=720, Percent_Identity=31.5277777777778, Blast_Score=315, Evalue=5e-86,
Organism=Drosophila melanogaster, GI17737937, Length=768, Percent_Identity=42.578125, Blast_Score=564, Evalue=1e-161,
Organism=Drosophila melanogaster, GI24647193, Length=763, Percent_Identity=32.6343381389253, Blast_Score=336, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24647199, Length=763, Percent_Identity=31.9790301441678, Blast_Score=328, Evalue=8e-90,
Organism=Drosophila melanogaster, GI24647201, Length=762, Percent_Identity=32.6771653543307, Blast_Score=318, Evalue=7e-87,
Organism=Drosophila melanogaster, GI24647195, Length=801, Percent_Identity=29.3383270911361, Blast_Score=281, Evalue=1e-75,
Organism=Drosophila melanogaster, GI24647197, Length=774, Percent_Identity=29.7157622739018, Blast_Score=281, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR017609 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 84242; Mature: 84242

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQAEPFLSVAANAERDAFKQVHVSRPHESAHLHVSGRATYTDDIPLVAGTLHAALGLS
CCCCCCCHHHHHCCCCHHHHHHHHCCCCCCCEEEEEECCEEECCCCCHHHHHHHHHHCCC
AKPHARIASMRLDAVRAAAGVVAVLTAADIPGANDCGPIVHDDPVLADGVVQYVGQPMFV
CCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEE
VVAASHDAARRAARLAQIEYEALPAILTAQAARAADSYVLPPMTLARGDAAERIARAVHR
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHC
DAGELTLGGQEQFYLEGQIAYAVPKEDGAMHVYSSTQHPSEMQHLVAHVLGLASHDVLVE
CCCCEEECCCCEEEEECEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHH
CRRMGGGFGGKESQSGLFACCAALAAWKLQCPVKLRPDRDDDMMITGKRHDFHYRYDVGY
HHHHCCCCCCCCCCCHHHHHHHHHHHHEECCCEEECCCCCCCEEEEECCCCEEEEEECCC
DDAGVIEGVSVDMTSRCGFSADLSGPVMTRAVCHFDNAYWLPDVSIVGRCGKTNTQSNTA
CCCCCCCCCEECHHHCCCCCCCCCCCHHHHHHHHCCCCEECCCHHHHCCCCCCCCCCCCE
FRGFGGPQGAFAIEYIIDSVARALGRDPLDVRRANLYGKTERNVTPYGQTIEDNVLPELI
EECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
AELEATSAYRARRAATRAFNAASPVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGS
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEECEEEEEEEEEEEEECCCCCEEEEEECCE
ILVNHGGTEMGQGLNTKVAQVVAHELGVDFARIRVTATDTSKVANTSATAASTGSDLNGK
EEEECCCHHHCCCCCHHHHHHHHHHHCCCEEEEEEEECCCHHHCCCCCCCCCCCCCCCCH
AAQDAARQLRERLAAFAAEHFGGGNARAADVRFARDEVRVGETAVPFEALAAQAYRARVQ
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHE
LWSDGFYATPKLHWDQATLRGRPFFYYAYGAAVSEVVVDTLTGEMRVLRADALHDVGASL
EECCCEEECCEEECCCHHHCCCCEEEEEHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCC
NPALDIGQVEGAFIQGMGWLTTEELWWNDGGKLMTHAPSTYKIPTVNDCPPDFRVKLFDN
CCCCCCCCCCCHHHCCCCCCEEHHEEECCCCEEEEECCCCEECCCCCCCCCCCEEEEECC
RNAEDSIHRSKAVGEPPLLLPFSVFFAIRDAVAAVGDYAINPPLAAPATGESILRAVQAV
CCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
RAARAGA
HHHHCCC
>Mature Secondary Structure
MNQQAEPFLSVAANAERDAFKQVHVSRPHESAHLHVSGRATYTDDIPLVAGTLHAALGLS
CCCCCCCHHHHHCCCCHHHHHHHHCCCCCCCEEEEEECCEEECCCCCHHHHHHHHHHCCC
AKPHARIASMRLDAVRAAAGVVAVLTAADIPGANDCGPIVHDDPVLADGVVQYVGQPMFV
CCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEE
VVAASHDAARRAARLAQIEYEALPAILTAQAARAADSYVLPPMTLARGDAAERIARAVHR
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHC
DAGELTLGGQEQFYLEGQIAYAVPKEDGAMHVYSSTQHPSEMQHLVAHVLGLASHDVLVE
CCCCEEECCCCEEEEECEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHH
CRRMGGGFGGKESQSGLFACCAALAAWKLQCPVKLRPDRDDDMMITGKRHDFHYRYDVGY
HHHHCCCCCCCCCCCHHHHHHHHHHHHEECCCEEECCCCCCCEEEEECCCCEEEEEECCC
DDAGVIEGVSVDMTSRCGFSADLSGPVMTRAVCHFDNAYWLPDVSIVGRCGKTNTQSNTA
CCCCCCCCCEECHHHCCCCCCCCCCCHHHHHHHHCCCCEECCCHHHHCCCCCCCCCCCCE
FRGFGGPQGAFAIEYIIDSVARALGRDPLDVRRANLYGKTERNVTPYGQTIEDNVLPELI
EECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
AELEATSAYRARRAATRAFNAASPVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGS
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEECEEEEEEEEEEEEECCCCCEEEEEECCE
ILVNHGGTEMGQGLNTKVAQVVAHELGVDFARIRVTATDTSKVANTSATAASTGSDLNGK
EEEECCCHHHCCCCCHHHHHHHHHHHCCCEEEEEEEECCCHHHCCCCCCCCCCCCCCCCH
AAQDAARQLRERLAAFAAEHFGGGNARAADVRFARDEVRVGETAVPFEALAAQAYRARVQ
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHE
LWSDGFYATPKLHWDQATLRGRPFFYYAYGAAVSEVVVDTLTGEMRVLRADALHDVGASL
EECCCEEECCEEECCCHHHCCCCEEEEEHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCC
NPALDIGQVEGAFIQGMGWLTTEELWWNDGGKLMTHAPSTYKIPTVNDCPPDFRVKLFDN
CCCCCCCCCCCHHHCCCCCCEEHHEEECCCCEEEEECCCCEECCCCCCCCCCCEEEEECC
RNAEDSIHRSKAVGEPPLLLPFSVFFAIRDAVAAVGDYAINPPLAAPATGESILRAVQAV
CCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
RAARAGA
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]