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The map label for this gene is tkt [H]

Identifier: 83719441

GI number: 83719441

Start: 1340636

End: 1342708

Strand: Direct

Name: tkt [H]

Synonym: BTH_I1195

Alternate gene names: 83719441

Gene position: 1340636-1342708 (Clockwise)

Preceding gene: 83719313

Following gene: 83720633

Centisome position: 35.19

GC content: 68.07

Gene sequence:

>2073_bases
ATGCCGCCCGTGCCCCGTTTTCTCGACTCGTTCTCCGGACTCGACATGACGACTTCGTCTCCCGCCTCCACCACCTTGAT
GGCCAACGCGATCCGCGCGCTCGCGATGGACGCCGTCCAGCAAGCGAACTCCGGTCACCCCGGCATGCCGATGGGCATGG
CCGAGATCGGCGTCGCGCTGTGGTCGCGCCACCTGAAGCACAACCCGACGAACCCGCATTGGGCCGACCGCGACCGCTTC
GTGCTGTCGAACGGCCACGGCTCGATGCTGCTGTACTCGCTGCTGCACCTGACAGGCTACGATCTGCCGATCGAAGAGCT
GAAGAATTTCCGGCAACTGCATTCGAAGACGCCGGGCCACCCGGAATACGGGATCACGCCGGGCGTCGAGACGACGACGG
GCCCGCTCGGCCAGGGCCTCGCGAACGCGGTCGGCATGGCGCTCGGCGAGGCGCTGCTCGCCGCCGAGTTCAACCGCGAC
GACGCGAAGATCGTCGATCACCACACGTACGTGTTCCTCGGCGACGGCTGCCTGATGGAAGGCATCTCGCACGAGGCCTG
CTCGCTCGCGGGCACGCTGAAGCTCAACAAGCTGATCGCGCTCTATGACGACAACGGGATCTCGATCGACGGCGACGTCG
TCAACTGGTTCCACGACGACACGCCGAAGCGCTTCGAGGCGTACGGCTGGAACGTGATTCCGAACGTGAACGGCCATGAC
GTCGACGCGATCGACGCGGCGATCGCGAAGGCGAAGCGCTCGGACAAGCCGAGCCTCATCTGCTGCAAGACGCGCATCGG
CAACGGCGCGGCGACGAAGGCGGGCGGCCACGACGTGCACGGCGCGCCGCTCGGCGCGGACGAAATCGCGAAGACCCGCG
AGGCGCTCGGCTGGACGTGGGCGCCGTTCGTGATTCCGCAGGAAGTCTATGCGGCATGGGACGCGAAGGAGGCGGGCAAG
CGCAGCGAAGACGACTGGAACGCGGCGTTCGCGCAATACCGCGCGAAGTACCCGGCCGAAGCGGCCGAATTCGAGCGCCG
GATGGCGGGCACGCTGCCGGCCGATTGGGCCGCGAAGGCCGCGGCGATCGTCGCCGGCGCGAACGAGCGCGGCGAGACGG
TCGCGACGCGCAAGGCGTCGCAGCAGACGATCGAGGGGCTCGCCGCCGTGCTGCCCGAGCTGCTCGGCGGCTCGGCGGAC
CTGACGGGCTCGAACCTCACGAACTGGAAGGCGTCGAAGGCGGTTCGCGCGAATGCGGACGGCCCGGGCGTCCAGTGGGG
CAACCATATCAACTACGGCGTGCGCGAATTCGGCATGAGCGCCGCGATCAACGGCCTCGTGCTGCACGGCGGCTACAAGC
CGTTCGGCGGCACGTTCCTCACGTTCTCCGACTACAGCCGCAATGCGCTGCGCGTCGCCGCGCTGATGAAGGTGCCGTCG
ATCTTCGTGTTCACGCACGATTCGATCGGCCTCGGCGAGGACGGCCCGACGCACCAGTCGGTCGAGCATGTCGCGAGCCT
GCGCCTGATTCCCAACCTCGACGTCTGGCGTCCGGCGGACACGGTGGAGACGGCCGTCGCGTGGACCTACGCGGTCGCGC
ACCAGCACCCGTCGTGCCTGATCTTCAGCCGCCAGAACCTCGCGTTCAACGCGCGCACCGATGCGCAGCTCGCGAACGTC
GAGAAGGGCGGCTACGTGCTGCGCGACTGGGACGAAGAAATCGTCGCGCGCAAGATCATCCTGATCGCGACGGGCTCCGA
AGTCGAGCTCGCGATGAAGGCGGTCGAGCCCCTCGCGCAGCAGGGGATCGCCGCGCGCGTCGTGTCGATGCCGTCGAGCG
ACGTGTTCGACCGCCAGGACGCCGAGTACCGCGAGCGGGTGCTGCCGCACGGCGTGCGCCGCGTCGCGATCGAAGCGGGC
GTCACCGATTTCTGGCGCAAGTACGTGGGCCTCGAAGGCGGCGTGGTCGGCATCGACACGTTCGGCGAGTCGGCCCCGGC
CGGCGTGCTGTTCAAGCATTTCGGCTTCACTGTCGAGCACGTGATCGAAACGGCGAAGGCGGTGCTCGCGTAA

Upstream 100 bases:

>100_bases
TTAAAATGACCCGCTTTGCAGCCTCGTCCGTCTGCTCGTCCGCATCGCGTCCCGCCGGCGCCGCACCGCGCGCCGGGAAC
GGTTTGCCCGCGAGCTTCGG

Downstream 100 bases:

>100_bases
CCCAATCGACGCCCGGGCGGCCGTGCCCTGCGCCGGCCGGGCGCGCGTGAAGCTGCACGAAGTATTTTTTCAGCCATCAG
GAGATACATCATGACGATTC

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MPPVPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRF
VLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALLAAEFNRD
DAKIVDHHTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
VDAIDAAIAKAKRSDKPSLICCKTRIGNGAATKAGGHDVHGAPLGADEIAKTREALGWTWAPFVIPQEVYAAWDAKEAGK
RSEDDWNAAFAQYRAKYPAEAAEFERRMAGTLPADWAAKAAAIVAGANERGETVATRKASQQTIEGLAAVLPELLGGSAD
LTGSNLTNWKASKAVRANADGPGVQWGNHINYGVREFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPS
IFVFTHDSIGLGEDGPTHQSVEHVASLRLIPNLDVWRPADTVETAVAWTYAVAHQHPSCLIFSRQNLAFNARTDAQLANV
EKGGYVLRDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSSDVFDRQDAEYRERVLPHGVRRVAIEAG
VTDFWRKYVGLEGGVVGIDTFGESAPAGVLFKHFGFTVEHVIETAKAVLA

Sequences:

>Translated_690_residues
MPPVPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRF
VLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALLAAEFNRD
DAKIVDHHTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
VDAIDAAIAKAKRSDKPSLICCKTRIGNGAATKAGGHDVHGAPLGADEIAKTREALGWTWAPFVIPQEVYAAWDAKEAGK
RSEDDWNAAFAQYRAKYPAEAAEFERRMAGTLPADWAAKAAAIVAGANERGETVATRKASQQTIEGLAAVLPELLGGSAD
LTGSNLTNWKASKAVRANADGPGVQWGNHINYGVREFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPS
IFVFTHDSIGLGEDGPTHQSVEHVASLRLIPNLDVWRPADTVETAVAWTYAVAHQHPSCLIFSRQNLAFNARTDAQLANV
EKGGYVLRDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSSDVFDRQDAEYRERVLPHGVRRVAIEAG
VTDFWRKYVGLEGGVVGIDTFGESAPAGVLFKHFGFTVEHVIETAKAVLA
>Mature_689_residues
PPVPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRFV
LSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALLAAEFNRDD
AKIVDHHTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHDV
DAIDAAIAKAKRSDKPSLICCKTRIGNGAATKAGGHDVHGAPLGADEIAKTREALGWTWAPFVIPQEVYAAWDAKEAGKR
SEDDWNAAFAQYRAKYPAEAAEFERRMAGTLPADWAAKAAAIVAGANERGETVATRKASQQTIEGLAAVLPELLGGSADL
TGSNLTNWKASKAVRANADGPGVQWGNHINYGVREFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPSI
FVFTHDSIGLGEDGPTHQSVEHVASLRLIPNLDVWRPADTVETAVAWTYAVAHQHPSCLIFSRQNLAFNARTDAQLANVE
KGGYVLRDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSSDVFDRQDAEYRERVLPHGVRRVAIEAGV
TDFWRKYVGLEGGVVGIDTFGESAPAGVLFKHFGFTVEHVIETAKAVLA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=605, Percent_Identity=27.7685950413223, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI4507521, Length=605, Percent_Identity=27.7685950413223, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI133778974, Length=274, Percent_Identity=33.2116788321168, Blast_Score=112, Evalue=9e-25,
Organism=Escherichia coli, GI48994911, Length=671, Percent_Identity=64.0834575260805, Blast_Score=877, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=666, Percent_Identity=60.6606606606607, Blast_Score=819, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=677, Percent_Identity=25.9970457902511, Blast_Score=152, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6325331, Length=672, Percent_Identity=50.1488095238095, Blast_Score=616, Evalue=1e-177,
Organism=Saccharomyces cerevisiae, GI6319593, Length=674, Percent_Identity=45.1038575667656, Blast_Score=550, Evalue=1e-157,
Organism=Drosophila melanogaster, GI24666278, Length=263, Percent_Identity=33.4600760456274, Blast_Score=124, Evalue=3e-28,
Organism=Drosophila melanogaster, GI45551847, Length=294, Percent_Identity=32.9931972789116, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI45550715, Length=294, Percent_Identity=32.9931972789116, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24645119, Length=245, Percent_Identity=33.8775510204082, Blast_Score=102, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 74352; Mature: 74220

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPVPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVAL
CCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
WSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGH
HHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
PEYGITPGVETTTGPLGQGLANAVGMALGEALLAAEFNRDDAKIVDHHTYVFLGDGCLME
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECEEEEEECCCHHHH
GISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
CCCHHHHHHHHHEEEEEEEEEECCCCCEECCCEEECCCCCCCCHHHHCCCEECCCCCCCC
VDAIDAAIAKAKRSDKPSLICCKTRIGNGAATKAGGHDVHGAPLGADEIAKTREALGWTW
CHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
APFVIPQEVYAAWDAKEAGKRSEDDWNAAFAQYRAKYPAEAAEFERRMAGTLPADWAAKA
CCCCCCHHHHHHCCCHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHH
AAIVAGANERGETVATRKASQQTIEGLAAVLPELLGGSADLTGSNLTNWKASKAVRANAD
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCC
GPGVQWGNHINYGVREFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPS
CCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCE
IFVFTHDSIGLGEDGPTHQSVEHVASLRLIPNLDVWRPADTVETAVAWTYAVAHQHPSCL
EEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
IFSRQNLAFNARTDAQLANVEKGGYVLRDWDEEIVARKIILIATGSEVELAMKAVEPLAQ
EEECCCCEEECCCCCHHHCCCCCCEEEECCHHHHHHCEEEEEEECCHHHHHHHHHHHHHH
QGIAARVVSMPSSDVFDRQDAEYRERVLPHGVRRVAIEAGVTDFWRKYVGLEGGVVGIDT
CCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEEC
FGESAPAGVLFKHFGFTVEHVIETAKAVLA
CCCCCCCHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PPVPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVAL
CCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
WSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGH
HHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
PEYGITPGVETTTGPLGQGLANAVGMALGEALLAAEFNRDDAKIVDHHTYVFLGDGCLME
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECEEEEEECCCHHHH
GISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
CCCHHHHHHHHHEEEEEEEEEECCCCCEECCCEEECCCCCCCCHHHHCCCEECCCCCCCC
VDAIDAAIAKAKRSDKPSLICCKTRIGNGAATKAGGHDVHGAPLGADEIAKTREALGWTW
CHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
APFVIPQEVYAAWDAKEAGKRSEDDWNAAFAQYRAKYPAEAAEFERRMAGTLPADWAAKA
CCCCCCHHHHHHCCCHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHH
AAIVAGANERGETVATRKASQQTIEGLAAVLPELLGGSADLTGSNLTNWKASKAVRANAD
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCC
GPGVQWGNHINYGVREFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPS
CCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCE
IFVFTHDSIGLGEDGPTHQSVEHVASLRLIPNLDVWRPADTVETAVAWTYAVAHQHPSCL
EEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
IFSRQNLAFNARTDAQLANVEKGGYVLRDWDEEIVARKIILIATGSEVELAMKAVEPLAQ
EEECCCCEEECCCCCHHHCCCCCCEEEECCHHHHHHCEEEEEEECCHHHHHHHHHHHHHH
QGIAARVVSMPSSDVFDRQDAEYRERVLPHGVRRVAIEAGVTDFWRKYVGLEGGVVGIDT
CCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEEC
FGESAPAGVLFKHFGFTVEHVIETAKAVLA
CCCCCCCHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]