Click here to switch to the map view.

The map label for this gene is ruvA

Identifier: 83719212

GI number: 83719212

Start: 1394184

End: 1394765

Strand: Reverse

Name: ruvA

Synonym: BTH_I1248

Alternate gene names: 83719212

Gene position: 1394765-1394184 (Counterclockwise)

Preceding gene: 161723182

Following gene: 83718669

Centisome position: 36.62

GC content: 67.18

Gene sequence:

>582_bases
ATGATCGGTCGCATCGCCGGCACCCTCCTCGAAAAGAATCCTCCGCGCATCCTCGTCGACTGCAACGGCGTCGGCTACGA
AGTCGACGTGCCGATGAGCACGTTCTACAACCTGCCTCACACGGGCGAGAAGGTCGTGCTGCTGACCCAGTTGATCGTCC
GCGAGGACGCACACCTGCTGTACGGCTTTCTCACGCCGCAGGAGCGCTCGACGTTCCGCGAGCTGCTCAAGATCACGGGC
GTGGGTGCGCGGATGGCGCTCGCCGTGCTGTCCGGCATGAGCGTCGCCGAACTGTCGCAAGCGGTCACCCTGCAGGACGC
CGCGCGCCTCACCCGCGTGCCGGGCATCGGCAAGAAGACGGCCGAGCGCCTGCTCCTCGAACTGAAGGGCAAGCTCGGCG
CCGATCTCGGCCCGCTCGCCGGCGCGGCCTCGCCTTCCGACCACGCGGCCGACATCCTCAACGCGCTCCTCGCGCTCGGC
TACTCGGAAAAGGAAGCGCTGGCCGCGATCAAGAACGTGCCGGCCGGCACCGGCGTGTCCGAAGGCATCAAGCTGTCGCT
CAAAGCGCTGTCGAAGGCGTAA

Upstream 100 bases:

>100_bases
GTCGGGTGACGCGCGTTCGTGCGGCGAGCGGCGGCGCGCACCGCCGCCCGCGCGCCGCGGTGCGCTACACTCGCGCTTTC
CGTTCCGTCCCGCACTCGCC

Downstream 100 bases:

>100_bases
CGGCGCGCCCTCGAATACAGCTTCGCATGCCGGGCGCCGCCCGGCGACTCGGCCGTTCGGCCAGGTTGGCCGGGGCACGC
CGCGCGGTACAATGGCCGCA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MIGRIAGTLLEKNPPRILVDCNGVGYEVDVPMSTFYNLPHTGEKVVLLTQLIVREDAHLLYGFLTPQERSTFRELLKITG
VGARMALAVLSGMSVAELSQAVTLQDAARLTRVPGIGKKTAERLLLELKGKLGADLGPLAGAASPSDHAADILNALLALG
YSEKEALAAIKNVPAGTGVSEGIKLSLKALSKA

Sequences:

>Translated_193_residues
MIGRIAGTLLEKNPPRILVDCNGVGYEVDVPMSTFYNLPHTGEKVVLLTQLIVREDAHLLYGFLTPQERSTFRELLKITG
VGARMALAVLSGMSVAELSQAVTLQDAARLTRVPGIGKKTAERLLLELKGKLGADLGPLAGAASPSDHAADILNALLALG
YSEKEALAAIKNVPAGTGVSEGIKLSLKALSKA
>Mature_193_residues
MIGRIAGTLLEKNPPRILVDCNGVGYEVDVPMSTFYNLPHTGEKVVLLTQLIVREDAHLLYGFLTPQERSTFRELLKITG
VGARMALAVLSGMSVAELSQAVTLQDAARLTRVPGIGKKTAERLLLELKGKLGADLGPLAGAASPSDHAADILNALLALG
YSEKEALAAIKNVPAGTGVSEGIKLSLKALSKA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=202, Percent_Identity=44.0594059405941, Blast_Score=166, Evalue=7e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_BURTA (Q2SZ54)

Other databases:

- EMBL:   CP000086
- RefSeq:   YP_441795.1
- HSSP:   P40832
- ProteinModelPortal:   Q2SZ54
- SMR:   Q2SZ54
- STRING:   Q2SZ54
- GeneID:   3849745
- GenomeReviews:   CP000086_GR
- KEGG:   bte:BTH_I1248
- TIGR:   BTH_I1248
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- ProtClustDB:   PRK00116
- BioCyc:   BTHA271848:BTH_I1248-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 20295; Mature: 20295

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRIAGTLLEKNPPRILVDCNGVGYEVDVPMSTFYNLPHTGEKVVLLTQLIVREDAHLL
CCCHHHHHHHCCCCCEEEEECCCCCEEEECCHHHHCCCCCCCCHHHHHHHHHHHCCCHHE
YGFLTPQERSTFRELLKITGVGARMALAVLSGMSVAELSQAVTLQDAARLTRVPGIGKKT
EEECCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLLLELKGKLGADLGPLAGAASPSDHAADILNALLALGYSEKEALAAIKNVPAGTGVS
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
EGIKLSLKALSKA
CCHHHHHHHHCCC
>Mature Secondary Structure
MIGRIAGTLLEKNPPRILVDCNGVGYEVDVPMSTFYNLPHTGEKVVLLTQLIVREDAHLL
CCCHHHHHHHCCCCCEEEEECCCCCEEEECCHHHHCCCCCCCCHHHHHHHHHHHCCCHHE
YGFLTPQERSTFRELLKITGVGARMALAVLSGMSVAELSQAVTLQDAARLTRVPGIGKKT
EEECCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLLLELKGKLGADLGPLAGAASPSDHAADILNALLALGYSEKEALAAIKNVPAGTGVS
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
EGIKLSLKALSKA
CCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA