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The map label for this gene is nrdD [C]

Identifier: 83718844

GI number: 83718844

Start: 2027066

End: 2028856

Strand: Reverse

Name: nrdD [C]

Synonym: BTH_I1809

Alternate gene names: 83718844

Gene position: 2028856-2027066 (Counterclockwise)

Preceding gene: 83719773

Following gene: 83720018

Centisome position: 53.26

GC content: 64.66

Gene sequence:

>1791_bases
TTGTGCCACCACCGAGAGAGGCCCACGTTGTCCGAGACCCTGCACCCCAGCGCCGCGTCGAATCCGGCGTCGCGCGACAA
GCCGCTGATCGACGTCGAATCGTCGATCAACGAATACCTGGACCGGCAGGACTGGCGCGTCAACGCGAACGCGAACCAGG
GCTATTCGCTCGGCGGCCTGATCCTGAACGTGTCCGGCAAGGTGATCGCGAACTACTGGCTGAGCCACGTCTACCCGAGC
GCGATCGGCGAAGCGCACCGCAACGCGGATCTGCACATCCACGATCTCGACGTGCTGTCCGGCTATTGCGCGGGCTGGTC
GCTGCGCACGCTGCTCACCGAAGGGCTGAACGGCGTGCCGGGCAAGGTCGAGTCGGGGCCGCCGAAGCACATGTCGAGCG
CGGTCGGCCAGATCGTGAACTTCCTCGGCACGCTGCAGAACGAATGGGCGGGCGCGCAGGCGTTCAGCTCGTTCGATACG
TACATGGCGCCGTTCGTGCGCCGCGACGCGCTCACCTACGCCGAAGTCCGGCAGTCCGTTCAGGAACTGATCTACAACCT
GAACGTGCCGTCGCGCTGGGGCACGCAGACGCCGTTCACGAACCTGACGTTCGACTGGATCTGCCCCGAGGATCTGCGCG
AGCAGGTGCCCGTGATCGCCGGCGAAGAGATGCCGTTCACGTACGGCGACCTGCAGCCCGAAATGGACATGATCAACCAG
GCGTACATCGAGGTGATGCAGGCGGGCGACGCGGCGGGCCGCGTGTTCACGTTCCCGATTCCGACCTACAACATCACGAC
CGATTTCGACTGGCACAGCCCGAACGCCGAGCGCCTGTTCGAGATGACCGCGCGCTACGGCCTGCCGTACTTCCAGAACT
TCATCAATTCGGAGCTGAAGCCGAACATGATCCGCTCGATGTGCTGCCGCCTTCAGCTCGACCTGCGCGAGCTGATGAAG
CGCGGCAACGGCCTGTTCGGCTCGGCCGAGCAGACGGGATCGATCGGCGTGGTCACCGTGAATTGCGCGCGGCTCGGCTA
TCTGCACGCGGGCGACGAGCGCGCGCTCTTCGCGCGGCTCGACACGCTGCTCGACTACGGAAAGGAAAGCCTCGAGATCA
AGCGCGAGGTGATCCAGCACCACATGAACAACGGGCTCTTCCCGTACACCAAGCGCTATCTCGGCACGCTGCGCAACCAT
TTCTCGACGCTCGGCGTGAACGGCATCAACGAGATGATCCGCAATTTCACGCGCGACGCGCACGATCTGACGACCGACTG
GGGCCACGCGTTCGCGCTGCGCCTGCTCGACCACGTGCGCGCGCGCATCGTCGAGTATCAGGAGGAAACGGGCCACATGT
ACAACCTCGAGGCGACGCCCGCCGAAGGCACGACGTACCGCTTCGCGAAGGAAGACCGCCGCCGCTATCCGGACATCCTG
CAGGCGGGCACGCCGCAGATGCCGTACTACACGAACTCGTCGCAGTTGCCGGTGGGCTTCACCGACGATCCGTTCGAGGC
GCTCGAACGCCAGGACGACCTGCAGCGCAAATACACGGGCGGCACGGTGCTGCATCTGTACATGACCGAGCCGCTGTCGT
CCGCCGACGCGTGCCGCACGCTCGTGAAGCGCGCGCTTACCCGCTTCTCGCTGCCGTATCTGACCGTCACGCCGACCTTC
TCGATCTGCCCGAAGCACGGCTATCTCGCCGGCAGCCACAAGTTTTGCCCGAAGTGCGACGAAGCGCTGCTGCGTCGCAA
ATTGTCTCAATCCCAACCGATGGAAGCCTGA

Upstream 100 bases:

>100_bases
TCGCATCGCCTTAATCGCCGTCAAGTACGCGCCGAACTTCGGCGAATCGACGTTGACCATCACAACATCTGGTATTTAGC
ATTCAGCCCATCACCAGATT

Downstream 100 bases:

>100_bases
ACATCATGACGACACAAGCCAACTCACAAGCCGCCCTCGCCTCGATCGCGCTGTCCGACGACGAACGTCAGCCATGCGAA
ATCTGGACCCGCGTGATGGG

Product: anaerobic ribonucleoside triphosphate reductase

Products: dUTP; H2O; Oxidized thioredoxin [C]

Alternate protein names: NA

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MCHHRERPTLSETLHPSAASNPASRDKPLIDVESSINEYLDRQDWRVNANANQGYSLGGLILNVSGKVIANYWLSHVYPS
AIGEAHRNADLHIHDLDVLSGYCAGWSLRTLLTEGLNGVPGKVESGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFSSFDT
YMAPFVRRDALTYAEVRQSVQELIYNLNVPSRWGTQTPFTNLTFDWICPEDLREQVPVIAGEEMPFTYGDLQPEMDMINQ
AYIEVMQAGDAAGRVFTFPIPTYNITTDFDWHSPNAERLFEMTARYGLPYFQNFINSELKPNMIRSMCCRLQLDLRELMK
RGNGLFGSAEQTGSIGVVTVNCARLGYLHAGDERALFARLDTLLDYGKESLEIKREVIQHHMNNGLFPYTKRYLGTLRNH
FSTLGVNGINEMIRNFTRDAHDLTTDWGHAFALRLLDHVRARIVEYQEETGHMYNLEATPAEGTTYRFAKEDRRRYPDIL
QAGTPQMPYYTNSSQLPVGFTDDPFEALERQDDLQRKYTGGTVLHLYMTEPLSSADACRTLVKRALTRFSLPYLTVTPTF
SICPKHGYLAGSHKFCPKCDEALLRRKLSQSQPMEA

Sequences:

>Translated_596_residues
MCHHRERPTLSETLHPSAASNPASRDKPLIDVESSINEYLDRQDWRVNANANQGYSLGGLILNVSGKVIANYWLSHVYPS
AIGEAHRNADLHIHDLDVLSGYCAGWSLRTLLTEGLNGVPGKVESGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFSSFDT
YMAPFVRRDALTYAEVRQSVQELIYNLNVPSRWGTQTPFTNLTFDWICPEDLREQVPVIAGEEMPFTYGDLQPEMDMINQ
AYIEVMQAGDAAGRVFTFPIPTYNITTDFDWHSPNAERLFEMTARYGLPYFQNFINSELKPNMIRSMCCRLQLDLRELMK
RGNGLFGSAEQTGSIGVVTVNCARLGYLHAGDERALFARLDTLLDYGKESLEIKREVIQHHMNNGLFPYTKRYLGTLRNH
FSTLGVNGINEMIRNFTRDAHDLTTDWGHAFALRLLDHVRARIVEYQEETGHMYNLEATPAEGTTYRFAKEDRRRYPDIL
QAGTPQMPYYTNSSQLPVGFTDDPFEALERQDDLQRKYTGGTVLHLYMTEPLSSADACRTLVKRALTRFSLPYLTVTPTF
SICPKHGYLAGSHKFCPKCDEALLRRKLSQSQPMEA
>Mature_596_residues
MCHHRERPTLSETLHPSAASNPASRDKPLIDVESSINEYLDRQDWRVNANANQGYSLGGLILNVSGKVIANYWLSHVYPS
AIGEAHRNADLHIHDLDVLSGYCAGWSLRTLLTEGLNGVPGKVESGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFSSFDT
YMAPFVRRDALTYAEVRQSVQELIYNLNVPSRWGTQTPFTNLTFDWICPEDLREQVPVIAGEEMPFTYGDLQPEMDMINQ
AYIEVMQAGDAAGRVFTFPIPTYNITTDFDWHSPNAERLFEMTARYGLPYFQNFINSELKPNMIRSMCCRLQLDLRELMK
RGNGLFGSAEQTGSIGVVTVNCARLGYLHAGDERALFARLDTLLDYGKESLEIKREVIQHHMNNGLFPYTKRYLGTLRNH
FSTLGVNGINEMIRNFTRDAHDLTTDWGHAFALRLLDHVRARIVEYQEETGHMYNLEATPAEGTTYRFAKEDRRRYPDIL
QAGTPQMPYYTNSSQLPVGFTDDPFEALERQDDLQRKYTGGTVLHLYMTEPLSSADACRTLVKRALTRFSLPYLTVTPTF
SICPKHGYLAGSHKFCPKCDEALLRRKLSQSQPMEA

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DOD-type homing endonuclease domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003586
- InterPro:   IPR003587
- InterPro:   IPR007869
- InterPro:   IPR006142
- InterPro:   IPR004042
- InterPro:   IPR006141
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF05204 Hom_end [H]

EC number: 1.17.4.2 [C]

Molecular weight: Translated: 67482; Mature: 67482

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCHHRERPTLSETLHPSAASNPASRDKPLIDVESSINEYLDRQDWRVNANANQGYSLGGL
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEECCCCCCCEECCE
ILNVSGKVIANYWLSHVYPSAIGEAHRNADLHIHDLDVLSGYCAGWSLRTLLTEGLNGVP
EEECCCHHHHHHHHHHHCHHHHHHHHCCCCCEEEEHHHHHHHHCCHHHHHHHHHCCCCCC
GKVESGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRRDALTYAEVRQSV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QELIYNLNVPSRWGTQTPFTNLTFDWICPEDLREQVPVIAGEEMPFTYGDLQPEMDMINQ
HHHHHHCCCCCCCCCCCCCCCCEEECCCCHHHHHCCCEEECCCCCCCCCCCCCHHHHHHH
AYIEVMQAGDAAGRVFTFPIPTYNITTDFDWHSPNAERLFEMTARYGLPYFQNFINSELK
HHHHHHHCCCCCCCEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCC
PNMIRSMCCRLQLDLRELMKRGNGLFGSAEQTGSIGVVTVNCARLGYLHAGDERALFARL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHCCEEECCCCHHHHHHH
DTLLDYGKESLEIKREVIQHHMNNGLFPYTKRYLGTLRNHFSTLGVNGINEMIRNFTRDA
HHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHH
HDLTTDWGHAFALRLLDHVRARIVEYQEETGHMYNLEATPAEGTTYRFAKEDRRRYPDIL
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHCHHHH
QAGTPQMPYYTNSSQLPVGFTDDPFEALERQDDLQRKYTGGTVLHLYMTEPLSSADACRT
HCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
LVKRALTRFSLPYLTVTPTFSICPKHGYLAGSHKFCPKCDEALLRRKLSQSQPMEA
HHHHHHHHHCCCEEEECCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MCHHRERPTLSETLHPSAASNPASRDKPLIDVESSINEYLDRQDWRVNANANQGYSLGGL
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEECCCCCCCEECCE
ILNVSGKVIANYWLSHVYPSAIGEAHRNADLHIHDLDVLSGYCAGWSLRTLLTEGLNGVP
EEECCCHHHHHHHHHHHCHHHHHHHHCCCCCEEEEHHHHHHHHCCHHHHHHHHHCCCCCC
GKVESGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRRDALTYAEVRQSV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QELIYNLNVPSRWGTQTPFTNLTFDWICPEDLREQVPVIAGEEMPFTYGDLQPEMDMINQ
HHHHHHCCCCCCCCCCCCCCCCEEECCCCHHHHHCCCEEECCCCCCCCCCCCCHHHHHHH
AYIEVMQAGDAAGRVFTFPIPTYNITTDFDWHSPNAERLFEMTARYGLPYFQNFINSELK
HHHHHHHCCCCCCCEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCC
PNMIRSMCCRLQLDLRELMKRGNGLFGSAEQTGSIGVVTVNCARLGYLHAGDERALFARL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHCCEEECCCCHHHHHHH
DTLLDYGKESLEIKREVIQHHMNNGLFPYTKRYLGTLRNHFSTLGVNGINEMIRNFTRDA
HHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHH
HDLTTDWGHAFALRLLDHVRARIVEYQEETGHMYNLEATPAEGTTYRFAKEDRRRYPDIL
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHCHHHH
QAGTPQMPYYTNSSQLPVGFTDDPFEALERQDDLQRKYTGGTVLHLYMTEPLSSADACRT
HCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
LVKRALTRFSLPYLTVTPTFSICPKHGYLAGSHKFCPKCDEALLRRKLSQSQPMEA
HHHHHHHHHCCCEEEECCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Ca2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Reduced thioredoxin; UTP [C]

Specific reaction: Reduced thioredoxin + UTP --> dUTP + H2O + Oxidized thioredoxin [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]