Click here to switch to the map view.

The map label for this gene is nhaA [H]

Identifier: 83718579

GI number: 83718579

Start: 1921486

End: 1922487

Strand: Direct

Name: nhaA [H]

Synonym: BTH_I1711

Alternate gene names: 83718579

Gene position: 1921486-1922487 (Clockwise)

Preceding gene: 83719236

Following gene: 83720989

Centisome position: 50.44

GC content: 67.76

Gene sequence:

>1002_bases
ATGTCCGATCAAATCAACCCGCCCGATTCGTCTTCGTCCCCCGCTGCGAACGCCGCCTCCCGAGAACCGAACTGGGAGCG
CGCCGTGCTCGAGCGCGTCGCGCTCGCGGCGATCAAGGAGCAGCGCGCCGCGCGACGCTGGAGGATCTTCTTCCGCTTCG
CGTTCCTCGCCGTGCTCGGCGCGCTCGCGTTCGCGTTCCTCAGCGTGTCCGGCGACGGCAGCAAGCTCGCGAGCGGCCGT
CACACGGCGGTCGTGACGATCGACGGCGAGATCGCCGCGAGCACCAACGCGAACGCCGAGGACATCAACACGGCGCTCGA
CAGCGCGTTCGAGGATTCGGGCACGGTCGGCGTCGTGCTGAAGATCAACAGCCCGGGCGGCAGCCCGGTGCAGGCGGGCA
TCGTCTACGACGAGATCCGCAGGCTGCGCAAGAAGTATCCGGCGAAGCCGCTTTACGTCGTCGTCTCCGACATGTGCGCG
TCGGGCGGCTATTACATCGCGGCGGCGGCGGACAAGATCTACGTCGACAAGGCGAGCATCGTCGGCTCGATCGGCGTGCT
GATGGACGGCTTCGGCTTCACCGGCCTGATGGACAAGCTGGGCGTCGAGCGGCGCCTGCACACGTCGGGCGAGAACAAGG
GCTTCTTCGATCCGTTCTCGCCGGAGACGCCGAAGATGGACGCGCACGCGCAGGAAATGCTCGACGAGATCCATGCGCAG
TTCATCAAGGCGGTGAAGGACGGCCGCGGCGCGCGGCTGCACGAATCGCCGGACATCTTTTCCGGACTCTTCTGGACGGG
CGCGAAGAGCATCGAGCTCGGCCTCGCCGACGATTACGGGACGACCGATTCTGTCGCGCGCGACGTGCTGAAGGCGCCGG
ATCTCGTCGACTACACGGTCAAGGAAAGCCTGACGGACCGCGTCGCGCGCCGCTTCGGCGCGGCGGTCGGCAAGGCCGCG
CTGAAGGCGGCCGTCGCCGGCGCCGAGCTGAAGCTGCGCTGA

Upstream 100 bases:

>100_bases
CGTCCAGGTCGACGAGCGGGACACGCCCGCCGGCCGGGCGGTGTTCTGGCTGCCCGACGGCGATCTGCGCCCGATCTCTT
CCGACCACTGATTTTCAAGC

Downstream 100 bases:

>100_bases
CGGCGCGCAGCGCTGCACCCGGTTCGCCGGGCTTCGCCTCAGTTCGCGAGCAGCAGGAAGATCGCGGGGCGCTTGTGCAG
ATCGGGCACAGGCGCCTTTT

Product: peptidase, U7 family protein

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSDQINPPDSSSSPAANAASREPNWERAVLERVALAAIKEQRAARRWRIFFRFAFLAVLGALAFAFLSVSGDGSKLASGR
HTAVVTIDGEIAASTNANAEDINTALDSAFEDSGTVGVVLKINSPGGSPVQAGIVYDEIRRLRKKYPAKPLYVVVSDMCA
SGGYYIAAAADKIYVDKASIVGSIGVLMDGFGFTGLMDKLGVERRLHTSGENKGFFDPFSPETPKMDAHAQEMLDEIHAQ
FIKAVKDGRGARLHESPDIFSGLFWTGAKSIELGLADDYGTTDSVARDVLKAPDLVDYTVKESLTDRVARRFGAAVGKAA
LKAAVAGAELKLR

Sequences:

>Translated_333_residues
MSDQINPPDSSSSPAANAASREPNWERAVLERVALAAIKEQRAARRWRIFFRFAFLAVLGALAFAFLSVSGDGSKLASGR
HTAVVTIDGEIAASTNANAEDINTALDSAFEDSGTVGVVLKINSPGGSPVQAGIVYDEIRRLRKKYPAKPLYVVVSDMCA
SGGYYIAAAADKIYVDKASIVGSIGVLMDGFGFTGLMDKLGVERRLHTSGENKGFFDPFSPETPKMDAHAQEMLDEIHAQ
FIKAVKDGRGARLHESPDIFSGLFWTGAKSIELGLADDYGTTDSVARDVLKAPDLVDYTVKESLTDRVARRFGAAVGKAA
LKAAVAGAELKLR
>Mature_332_residues
SDQINPPDSSSSPAANAASREPNWERAVLERVALAAIKEQRAARRWRIFFRFAFLAVLGALAFAFLSVSGDGSKLASGRH
TAVVTIDGEIAASTNANAEDINTALDSAFEDSGTVGVVLKINSPGGSPVQAGIVYDEIRRLRKKYPAKPLYVVVSDMCAS
GGYYIAAAADKIYVDKASIVGSIGVLMDGFGFTGLMDKLGVERRLHTSGENKGFFDPFSPETPKMDAHAQEMLDEIHAQF
IKAVKDGRGARLHESPDIFSGLFWTGAKSIELGLADDYGTTDSVARDVLKAPDLVDYTVKESLTDRVARRFGAAVGKAAL
KAAVAGAELKLR

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=221, Percent_Identity=33.4841628959276, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1788064, Length=241, Percent_Identity=27.3858921161826, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR002142 [H]

Pfam domain/function: PF06965 Na_H_antiport_1; PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 35576; Mature: 35444

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQINPPDSSSSPAANAASREPNWERAVLERVALAAIKEQRAARRWRIFFRFAFLAVLG
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAFAFLSVSGDGSKLASGRHTAVVTIDGEIAASTNANAEDINTALDSAFEDSGTVGVVL
HHHHHHHHCCCCCCHHCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCEEEEE
KINSPGGSPVQAGIVYDEIRRLRKKYPAKPLYVVVSDMCASGGYYIAAAADKIYVDKASI
EEECCCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCEEEEEHHHH
VGSIGVLMDGFGFTGLMDKLGVERRLHTSGENKGFFDPFSPETPKMDAHAQEMLDEIHAQ
HHHHHHHHCCCCHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FIKAVKDGRGARLHESPDIFSGLFWTGAKSIELGLADDYGTTDSVARDVLKAPDLVDYTV
HHHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHH
KESLTDRVARRFGAAVGKAALKAAVAGAELKLR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
>Mature Secondary Structure 
SDQINPPDSSSSPAANAASREPNWERAVLERVALAAIKEQRAARRWRIFFRFAFLAVLG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAFAFLSVSGDGSKLASGRHTAVVTIDGEIAASTNANAEDINTALDSAFEDSGTVGVVL
HHHHHHHHCCCCCCHHCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCEEEEE
KINSPGGSPVQAGIVYDEIRRLRKKYPAKPLYVVVSDMCASGGYYIAAAADKIYVDKASI
EEECCCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCEEEEEHHHH
VGSIGVLMDGFGFTGLMDKLGVERRLHTSGENKGFFDPFSPETPKMDAHAQEMLDEIHAQ
HHHHHHHHCCCCHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FIKAVKDGRGARLHESPDIFSGLFWTGAKSIELGLADDYGTTDSVARDVLKAPDLVDYTV
HHHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHH
KESLTDRVARRFGAAVGKAALKAAVAGAELKLR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA