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The map label for this gene is dapE [H]

Identifier: 83718475

GI number: 83718475

Start: 2279924

End: 2281075

Strand: Reverse

Name: dapE [H]

Synonym: BTH_I2014

Alternate gene names: 83718475

Gene position: 2281075-2279924 (Counterclockwise)

Preceding gene: 83719389

Following gene: 83721211

Centisome position: 59.88

GC content: 68.66

Gene sequence:

>1152_bases
GTGGTCCGAACCATGTCCGCCACCCTTGCCCTCACCGAACAGCTGATCGCGCGCGCGTCCGTCACGCCCGACGATCAGCA
CTGCCAGCAGTTGATGATCGAGCGCCTCGCCGCGCTCGGCTTCGAGTGCGAAACGATCGCGTCGCACGGCGTGACGAACT
TCTGGGCCGTCAAGCGCGGCACGGCCGGCCGCGAAGGCAAGCTGCTCGCGTTCGCGGGCCATACCGACGTCGTGCCGACC
GGCCCGCTCGAGCAATGGAGCTCGCCGCCGTTCGTGCCGACGCACCGCGACGGCAAGCTGTACGGCCGCGGCGCGGCCGA
CATGAAAGCATCGCTCGCGGGCTTCGTCGTCGCGGCGGAGGAATTCGTCGCCGCGCATCCGCAGCACCGCGGCTCGATCG
GTTTCCTGATCACGAGCGACGAGGAAGGCCCGGCCACCGACGGCACCGTGAAGGTCGTCGAAGCGCTCGCCGCGCGCGGC
GAGCGGCTCGATTACTGCATCGTCGGCGAGCCGACCTCGACGGCGACGCTCGGCGACGTCGTGAAGAACGGCCGGCGCGG
CTCGATGTCGGGCGAGCTCGTCGTCAAGGGCGTGCAAGGCCACATCGCGTATCCGCATCTCGCGAAGAATCCGATCCATC
TGCTCGCGCCGGCGCTCGCCGAGCTCGCGGCCGAGCAATGGGACGAAGGCAACGAGTACTTTCCGCCGACCACCTGGCAA
GTGTCGAACCTGCGCGCGGGCACCGGCGCGACGAACGTGATTCCGGGCCACGCCGATCTGCTGTTCAACTTCCGCTTCTC
GACGGCGAGCACGGTCGAGGGCCTGCAGGCGCGCGTGCACGCGATCCTCGACAAGCACGGGCTCGATTACGCGCTGAACT
GGTCGGTGAGCGGCCTGCCGTTCCTCACGCCGCGCGGCGAGCTGTCGAACGCGCTCGACGCGGCGATTCGCGCGGAAACC
GGCCTGTCGCCCGAGCTGTCGACGACGGGCGGCACGTCGGACGGCCGCTTCATCGCGCGCATCTGCCCGCAGGTGATCGA
GTTCGGCCCGCCGAACGCGAGCATCCACAAGATCGACGAGCACATCGAAGTGCGCTTCGTCGAACCGCTGAAGAACGTGT
ACCGCCGCGTGCTCGAACAACTGATCGCTTGA

Upstream 100 bases:

>100_bases
GGCTTCTCGGCCGACGAGTACGCGGGGCTCTTCGCCTAACGCCGCGCGCACCGCCGCCCCAACCTGCTGCCGGCCGTCGC
GCCGGCATTTTTTATCGAAA

Downstream 100 bases:

>100_bases
CGAAGGCCATCCGATGACGACATCCCCCTCCCCGTTCAAGACCGTCCGCGACCTCGTGCGCTACGCGGTGTCGCGCTTCT
CGCAGGCGAAACTCGCGTTC

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MVRTMSATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRGTAGREGKLLAFAGHTDVVPT
GPLEQWSSPPFVPTHRDGKLYGRGAADMKASLAGFVVAAEEFVAAHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARG
ERLDYCIVGEPTSTATLGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQ
VSNLRAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDKHGLDYALNWSVSGLPFLTPRGELSNALDAAIRAET
GLSPELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHIEVRFVEPLKNVYRRVLEQLIA

Sequences:

>Translated_383_residues
MVRTMSATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRGTAGREGKLLAFAGHTDVVPT
GPLEQWSSPPFVPTHRDGKLYGRGAADMKASLAGFVVAAEEFVAAHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARG
ERLDYCIVGEPTSTATLGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQ
VSNLRAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDKHGLDYALNWSVSGLPFLTPRGELSNALDAAIRAET
GLSPELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHIEVRFVEPLKNVYRRVLEQLIA
>Mature_383_residues
MVRTMSATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRGTAGREGKLLAFAGHTDVVPT
GPLEQWSSPPFVPTHRDGKLYGRGAADMKASLAGFVVAAEEFVAAHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARG
ERLDYCIVGEPTSTATLGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQ
VSNLRAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDKHGLDYALNWSVSGLPFLTPRGELSNALDAAIRAET
GLSPELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHIEVRFVEPLKNVYRRVLEQLIA

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=376, Percent_Identity=57.9787234042553, Blast_Score=445, Evalue=1e-126,
Organism=Escherichia coli, GI1790395, Length=395, Percent_Identity=25.3164556962025, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 41137; Mature: 41137

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRTMSATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRG
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEECC
TAGREGKLLAFAGHTDVVPTGPLEQWSSPPFVPTHRDGKLYGRGAADMKASLAGFVVAAE
CCCCCCCEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHH
EFVAAHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARGERLDYCIVGEPTSTATLGDV
HHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
VKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQ
HHCCCCCCCCCCEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
VSNLRAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDKHGLDYALNWSVSGLP
ECCEECCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
FLTPRGELSNALDAAIRAETGLSPELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDE
EECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCC
HIEVRFVEPLKNVYRRVLEQLIA
HHEEEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVRTMSATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRG
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEECC
TAGREGKLLAFAGHTDVVPTGPLEQWSSPPFVPTHRDGKLYGRGAADMKASLAGFVVAAE
CCCCCCCEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHH
EFVAAHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARGERLDYCIVGEPTSTATLGDV
HHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
VKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQ
HHCCCCCCCCCCEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
VSNLRAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDKHGLDYALNWSVSGLP
ECCEECCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
FLTPRGELSNALDAAIRAETGLSPELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDE
EECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCC
HIEVRFVEPLKNVYRRVLEQLIA
HHEEEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA