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The map label for this gene is gyaR [H]

Identifier: 161723179

GI number: 161723179

Start: 1908673

End: 1909662

Strand: Direct

Name: gyaR [H]

Synonym: BTH_I1700

Alternate gene names: 161723179

Gene position: 1908673-1909662 (Clockwise)

Preceding gene: 83719247

Following gene: 83721617

Centisome position: 50.11

GC content: 69.39

Gene sequence:

>990_bases
ATGCAGAAAATCCTGGTCGCACGCTCGATCTTTCCGGACGTGATCGAGCGGCTCAAGCAGTATTTCGACGTCGACTGGAA
CGACGGCGACGCGCTCGCCCCCGACGCGCTGAAGGCGCGCCTCGCGGACAAGGACGGCGCGCTGACGGCGGGCGACATGA
TCGACGCGTCGGTGCTCGCGGCGGCGCCGCGGCTGCGCGTCGTGTCGAACATGGCGGTCGGCTACAACAACTTCGACATC
GGCGCGTTCGACGCCGCGCACGTGCTCGGCACCAACACGCCCGACGTGCTGACCGAGACGACCGCCGATTTCGGCTGGGC
GCTGATGATGGCGGCCGCGCGGCGGATCGCCGAATCCGAGCACTGGCTGCGCGCGGGGCGGTGGCGCAAGTGGTCGTACG
ACAGCTTTCTCGGCGCGGACATTCACGGCGCGACGCTCGGCGTGATCGGCATGGGCCGCATCGGTCAGGCGCTCGCGCGC
CGCGCGCGCGGCTTCGGCATGCGCGTGATCTATCACAACCGCTCGCGCGTCGCGCCCGAGATCGAGGCCGAGCTGAACGC
CGAATATGCGTCGAAGGCGGCGCTGCTCGCGCAAGCGGATCACGTCGTGCTCGTGCTGCCTTACTCGGCGGAAAGTCATC
ACACGATCGGCGCGGCCGAGCTTGCGATGATGAAGCCGAGCGCGACGCTCACGAACATCGCGCGCGGCGGGATCGTCGAC
GACGCGGCGCTCGCCGACGCATTGCGCAACAAACGGATCGCCGCAGCGGGCCTCGACGTGTTCGAAGGCGAGCCGAGCGT
GCATCCGGCGCTGCTCGAGGTGCCCAACGTCGTGCTGACGCCGCACATCGCGAGCGCGAGCGAAGGCACGCGTCGCGCGA
TGGCGAATCTCGCGGCGGACAACCTGATCGCGGCGCTCGGCGCGGGCCCGGATGCGGGCCGTCCGCCTAACCCGATCAAT
CCCGGCGTGCTGGGGAAGGCTCGCATATGA

Upstream 100 bases:

>100_bases
GGGTGTTCTTCAGCGGTTAGGCGGATGAATGACGGCCGCGCGGGCGGCGGGCGGCGCGATTGCGCGCGCTCGCCGCCCGC
GCGGCGTGACGGAGACGGCA

Downstream 100 bases:

>100_bases
CCGAAACCTTGTTGCTGGCCGCCGTCGTCGCGCTCGCGGTGGCGCTTGTCGTCGCGCTCGTCGTGCTGCTGCGCGGCGGC
TCGCGCGGCGATGGCCTCGA

Product: glyoxylate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MQKILVARSIFPDVIERLKQYFDVDWNDGDALAPDALKARLADKDGALTAGDMIDASVLAAAPRLRVVSNMAVGYNNFDI
GAFDAAHVLGTNTPDVLTETTADFGWALMMAAARRIAESEHWLRAGRWRKWSYDSFLGADIHGATLGVIGMGRIGQALAR
RARGFGMRVIYHNRSRVAPEIEAELNAEYASKAALLAQADHVVLVLPYSAESHHTIGAAELAMMKPSATLTNIARGGIVD
DAALADALRNKRIAAAGLDVFEGEPSVHPALLEVPNVVLTPHIASASEGTRRAMANLAADNLIAALGAGPDAGRPPNPIN
PGVLGKARI

Sequences:

>Translated_329_residues
MQKILVARSIFPDVIERLKQYFDVDWNDGDALAPDALKARLADKDGALTAGDMIDASVLAAAPRLRVVSNMAVGYNNFDI
GAFDAAHVLGTNTPDVLTETTADFGWALMMAAARRIAESEHWLRAGRWRKWSYDSFLGADIHGATLGVIGMGRIGQALAR
RARGFGMRVIYHNRSRVAPEIEAELNAEYASKAALLAQADHVVLVLPYSAESHHTIGAAELAMMKPSATLTNIARGGIVD
DAALADALRNKRIAAAGLDVFEGEPSVHPALLEVPNVVLTPHIASASEGTRRAMANLAADNLIAALGAGPDAGRPPNPIN
PGVLGKARI
>Mature_329_residues
MQKILVARSIFPDVIERLKQYFDVDWNDGDALAPDALKARLADKDGALTAGDMIDASVLAAAPRLRVVSNMAVGYNNFDI
GAFDAAHVLGTNTPDVLTETTADFGWALMMAAARRIAESEHWLRAGRWRKWSYDSFLGADIHGATLGVIGMGRIGQALAR
RARGFGMRVIYHNRSRVAPEIEAELNAEYASKAALLAQADHVVLVLPYSAESHHTIGAAELAMMKPSATLTNIARGGIVD
DAALADALRNKRIAAAGLDVFEGEPSVHPALLEVPNVVLTPHIASASEGTRRAMANLAADNLIAALGAGPDAGRPPNPIN
PGVLGKARI

Specific function: Unknown

COG id: COG1052

COG function: function code CHR; Lactate dehydrogenase and related dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912396, Length=317, Percent_Identity=34.384858044164, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI23308577, Length=302, Percent_Identity=29.1390728476821, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI145580578, Length=265, Percent_Identity=36.2264150943396, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI4557499, Length=265, Percent_Identity=36.2264150943396, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI61743967, Length=258, Percent_Identity=35.2713178294574, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI4557497, Length=258, Percent_Identity=35.2713178294574, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI145580575, Length=250, Percent_Identity=36.4, Blast_Score=119, Evalue=5e-27,
Organism=Escherichia coli, GI87082289, Length=325, Percent_Identity=41.8461538461538, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI1789279, Length=309, Percent_Identity=28.8025889967638, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1787645, Length=258, Percent_Identity=29.0697674418605, Blast_Score=105, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17532191, Length=305, Percent_Identity=30.1639344262295, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25147481, Length=252, Percent_Identity=25, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324055, Length=246, Percent_Identity=34.1463414634146, Blast_Score=153, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6320925, Length=273, Percent_Identity=26.3736263736264, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6322116, Length=325, Percent_Identity=24.6153846153846, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6325144, Length=144, Percent_Identity=31.9444444444444, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6321253, Length=166, Percent_Identity=29.5180722891566, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28574286, Length=315, Percent_Identity=35.8730158730159, Blast_Score=175, Evalue=3e-44,
Organism=Drosophila melanogaster, GI45551003, Length=313, Percent_Identity=35.7827476038339, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24585514, Length=313, Percent_Identity=35.7827476038339, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28574282, Length=313, Percent_Identity=35.7827476038339, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28574284, Length=313, Percent_Identity=35.7827476038339, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI45552429, Length=313, Percent_Identity=35.7827476038339, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI28571528, Length=313, Percent_Identity=35.4632587859425, Blast_Score=164, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24585516, Length=260, Percent_Identity=33.8461538461538, Blast_Score=147, Evalue=9e-36,
Organism=Drosophila melanogaster, GI19921140, Length=315, Percent_Identity=29.8412698412698, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24646446, Length=267, Percent_Identity=34.0823970037453, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646448, Length=267, Percent_Identity=34.0823970037453, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646452, Length=267, Percent_Identity=34.0823970037453, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646450, Length=267, Percent_Identity=34.0823970037453, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI62472511, Length=261, Percent_Identity=34.0996168582375, Blast_Score=121, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006139
- InterPro:   IPR006140
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00389 2-Hacid_dh; PF02826 2-Hacid_dh_C [H]

EC number: =1.1.1.26 [H]

Molecular weight: Translated: 34933; Mature: 34933

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00065 D_2_HYDROXYACID_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKILVARSIFPDVIERLKQYFDVDWNDGDALAPDALKARLADKDGALTAGDMIDASVLA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCEEECHHHHHHHHH
AAPRLRVVSNMAVGYNNFDIGAFDAAHVLGTNTPDVLTETTADFGWALMMAAARRIAESE
HCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HWLRAGRWRKWSYDSFLGADIHGATLGVIGMGRIGQALARRARGFGMRVIYHNRSRVAPE
HHHHHCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCH
IEAELNAEYASKAALLAQADHVVLVLPYSAESHHTIGAAELAMMKPSATLTNIARGGIVD
HHHHCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHEECCCHHHHHHHCCCCCC
DAALADALRNKRIAAAGLDVFEGEPSVHPALLEVPNVVLTPHIASASEGTRRAMANLAAD
HHHHHHHHHCCCEEECCCHHCCCCCCCCHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHH
NLIAALGAGPDAGRPPNPINPGVLGKARI
HHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQKILVARSIFPDVIERLKQYFDVDWNDGDALAPDALKARLADKDGALTAGDMIDASVLA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCEEECHHHHHHHHH
AAPRLRVVSNMAVGYNNFDIGAFDAAHVLGTNTPDVLTETTADFGWALMMAAARRIAESE
HCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HWLRAGRWRKWSYDSFLGADIHGATLGVIGMGRIGQALARRARGFGMRVIYHNRSRVAPE
HHHHHCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCH
IEAELNAEYASKAALLAQADHVVLVLPYSAESHHTIGAAELAMMKPSATLTNIARGGIVD
HHHHCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHEECCCHHHHHHHCCCCCC
DAALADALRNKRIAAAGLDVFEGEPSVHPALLEVPNVVLTPHIASASEGTRRAMANLAAD
HHHHHHHHHCCCEEECCCHHCCCCCCCCHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHH
NLIAALGAGPDAGRPPNPINPGVLGKARI
HHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA