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The map label for this gene is hmeD [H]

Identifier: 83590446

GI number: 83590446

Start: 1641469

End: 1643094

Strand: Reverse

Name: hmeD [H]

Synonym: Moth_1606

Alternate gene names: 83590446

Gene position: 1643094-1641469 (Counterclockwise)

Preceding gene: 83590447

Following gene: 83590445

Centisome position: 62.5

GC content: 56.52

Gene sequence:

>1626_bases
ATGGCAGCTATTCCTAAACCTGAGGAATTAGTAAAGATAAATTACCGGCCTCCCCGGACGGGGTGGATGGATACTCCGGT
GCAATTCCGGCGGGGCAACTACCTATACGCCGCTAAACCCAAGAGCCTGGAAGTCGTCGGCCTGCCCAATCCCAGGGAAT
GGTCGCCGGAAGACGAGGATTGGAAACTACCGGAAAACTGGCAGGAGATTATCCTGGAAGGTCTGCGGGAACGCCTGGGA
CGCTTCCGCTCGCTGCAGGTTTTCATGGATATCTGCGTCCGCTGTGGCGCCTGTGCCGATAAATGCCATTTCTTCATCGG
CACCGGCGATCCCAAGAATATGCCTGTCCTGCGGGCCGAGCTCCTGCGCTCGGTATACCGTCGCGACTTTACTACCGCCG
GTAAGCTCCTGGGAAGACTCGTCGGCGCCAGGGATTTAACGGTCGATGTCCTGAAGGAATGGTTCTACTACTTTTTTCAG
TGCACCGAGTGCCGCCGCTGCTCCCTCTTCTGCCCCTACGGCATTGATACGGCGGAAATCACCATGATCGGCCGGGAACT
CCTCAACCTGGTCGGGTGCAATATCGACTGGATTGCTTCTCCGGTGGCCAACTGCTACCGCACCGGGAACCACGTCGGCA
TCGAACCCCACGCCTTCAAGGATATGGTGGAGTTCTGTGTCGACGAAATCGAAAACATAACCGGCATCAGGGTGGAACCT
ACCTTCAACCGCAAGGGGGCGGAGGTGCTCTTTATCGCCCCTTCCGGCGACGTTTTCGCTGACCCCGGGACCTACACCCT
CATGGGCTATCTTATGCTCTTCCACGAGATCGGCCTGGATTACACCTGGAGTACCTACGCCTCCGAGGGCGGCAACTTTG
GTATGTTCACCTCCCACGAAATGATGAAGAGGCTCAACGCCAAGATGTACGCCGAGGCCAAACGCCTGGGGGTGAAGTGG
ATCCTTGGGGGCGAGTGCGGCCACATGTGGCGGGTCATTAACCAGTATATGGATACCATGAACGGCCCGGCCGATTTCCT
GGAAGTGCCCGTTTCCCCCATCACCGGCACGAGGTTTGAGAACGCCAAATCAACCAAGATGGTCCATATCACCGAATTTA
CGGCGGACTTGATCAAGCACAATAAGCTAAAACTGGACCCCAGCCGCAACGATAACCTGCGGGTTACCTTCCATGACTCC
TGCAACCCGGCGCGATCCATGGGGCTTTTTGAGGAACCGCGTTACATCATCAAGCATGTCTGCAATAATTTCTTCGAGAT
GCCCGAGAACACCATCAGGGAAAAGACTTTTTGCTGTGGCAGCGGTGCCGGCCTTAACGCTGATGAATATATGGAGATGC
GGATGCGGGGCGGCCTGCCCCGGGCCAATGCAGTAAAGTATGTTCACGAAAAATACGGCGTTAATATGCTGGCCTGCATC
TGTGCCGTGGACCGGGCCGTCTTCCCGGCCTTGATGGAGTACTGGGTACCCGGGGTTGGAGTCACCGGCGTCCATGAGCT
GGTGGGCAATGCCCTGGTAATGAAGGGTGAAAAAGAGAGAACGACTAACCTGCGGGGTGAACCCTTGCCCGGCAAAGAAG
GGGCGGTAGATGGCGATGTATCGTGA

Upstream 100 bases:

>100_bases
TGGCCTGCCGGGAGAAGCTTTATGAGATCCGGGTTCAAGAAGTAAAAAACCGGATCGCCAGATTACTGCAAAAAGCCAAT
CTCCTTGAGAAGGTGTGAAA

Downstream 100 bases:

>100_bases
TGCCCGTTATATCATAACCGGCCTGGTGATCTTTGTGGGTTTGATGACCTTCCCCTTTTGGTCCAATGCCGGCCGGGCCG
CCCCGGCGCCGGCACCAAAC

Product: 4Fe-4S ferredoxin, iron-sulfur binding

Products: NA

Alternate protein names: Hme subunit D [H]

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MAAIPKPEELVKINYRPPRTGWMDTPVQFRRGNYLYAAKPKSLEVVGLPNPREWSPEDEDWKLPENWQEIILEGLRERLG
RFRSLQVFMDICVRCGACADKCHFFIGTGDPKNMPVLRAELLRSVYRRDFTTAGKLLGRLVGARDLTVDVLKEWFYYFFQ
CTECRRCSLFCPYGIDTAEITMIGRELLNLVGCNIDWIASPVANCYRTGNHVGIEPHAFKDMVEFCVDEIENITGIRVEP
TFNRKGAEVLFIAPSGDVFADPGTYTLMGYLMLFHEIGLDYTWSTYASEGGNFGMFTSHEMMKRLNAKMYAEAKRLGVKW
ILGGECGHMWRVINQYMDTMNGPADFLEVPVSPITGTRFENAKSTKMVHITEFTADLIKHNKLKLDPSRNDNLRVTFHDS
CNPARSMGLFEEPRYIIKHVCNNFFEMPENTIREKTFCCGSGAGLNADEYMEMRMRGGLPRANAVKYVHEKYGVNMLACI
CAVDRAVFPALMEYWVPGVGVTGVHELVGNALVMKGEKERTTNLRGEPLPGKEGAVDGDVS

Sequences:

>Translated_541_residues
MAAIPKPEELVKINYRPPRTGWMDTPVQFRRGNYLYAAKPKSLEVVGLPNPREWSPEDEDWKLPENWQEIILEGLRERLG
RFRSLQVFMDICVRCGACADKCHFFIGTGDPKNMPVLRAELLRSVYRRDFTTAGKLLGRLVGARDLTVDVLKEWFYYFFQ
CTECRRCSLFCPYGIDTAEITMIGRELLNLVGCNIDWIASPVANCYRTGNHVGIEPHAFKDMVEFCVDEIENITGIRVEP
TFNRKGAEVLFIAPSGDVFADPGTYTLMGYLMLFHEIGLDYTWSTYASEGGNFGMFTSHEMMKRLNAKMYAEAKRLGVKW
ILGGECGHMWRVINQYMDTMNGPADFLEVPVSPITGTRFENAKSTKMVHITEFTADLIKHNKLKLDPSRNDNLRVTFHDS
CNPARSMGLFEEPRYIIKHVCNNFFEMPENTIREKTFCCGSGAGLNADEYMEMRMRGGLPRANAVKYVHEKYGVNMLACI
CAVDRAVFPALMEYWVPGVGVTGVHELVGNALVMKGEKERTTNLRGEPLPGKEGAVDGDVS
>Mature_540_residues
AAIPKPEELVKINYRPPRTGWMDTPVQFRRGNYLYAAKPKSLEVVGLPNPREWSPEDEDWKLPENWQEIILEGLRERLGR
FRSLQVFMDICVRCGACADKCHFFIGTGDPKNMPVLRAELLRSVYRRDFTTAGKLLGRLVGARDLTVDVLKEWFYYFFQC
TECRRCSLFCPYGIDTAEITMIGRELLNLVGCNIDWIASPVANCYRTGNHVGIEPHAFKDMVEFCVDEIENITGIRVEPT
FNRKGAEVLFIAPSGDVFADPGTYTLMGYLMLFHEIGLDYTWSTYASEGGNFGMFTSHEMMKRLNAKMYAEAKRLGVKWI
LGGECGHMWRVINQYMDTMNGPADFLEVPVSPITGTRFENAKSTKMVHITEFTADLIKHNKLKLDPSRNDNLRVTFHDSC
NPARSMGLFEEPRYIIKHVCNNFFEMPENTIREKTFCCGSGAGLNADEYMEMRMRGGLPRANAVKYVHEKYGVNMLACIC
AVDRAVFPALMEYWVPGVGVTGVHELVGNALVMKGEKERTTNLRGEPLPGKEGAVDGDVS

Specific function: Has menaquinol-oxidizing activity. HmeC and hmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR009051 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 61323; Mature: 61192

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAIPKPEELVKINYRPPRTGWMDTPVQFRRGNYLYAAKPKSLEVVGLPNPREWSPEDED
CCCCCCCHHEEEEECCCCCCCCCCCCHHCCCCCEEEEECCCCEEEEECCCCCCCCCCCCC
WKLPENWQEIILEGLRERLGRFRSLQVFMDICVRCGACADKCHFFIGTGDPKNMPVLRAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHH
LLRSVYRRDFTTAGKLLGRLVGARDLTVDVLKEWFYYFFQCTECRRCSLFCPYGIDTAEI
HHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHH
TMIGRELLNLVGCNIDWIASPVANCYRTGNHVGIEPHAFKDMVEFCVDEIENITGIRVEP
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECC
TFNRKGAEVLFIAPSGDVFADPGTYTLMGYLMLFHEIGLDYTWSTYASEGGNFGMFTSHE
CCCCCCCEEEEEECCCCCEECCCHHHHHHHHHHHHHHCCCCEEHHHHCCCCCCCCCCHHH
MMKRLNAKMYAEAKRLGVKWILGGECGHMWRVINQYMDTMNGPADFLEVPVSPITGTRFE
HHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCC
NAKSTKMVHITEFTADLIKHNKLKLDPSRNDNLRVTFHDSCNPARSMGLFEEPRYIIKHV
CCCCCEEEEEHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCHHHHCCCCCCCHHHHHHH
CNNFFEMPENTIREKTFCCGSGAGLNADEYMEMRMRGGLPRANAVKYVHEKYGVNMLACI
HHHHHHCCHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHH
CAVDRAVFPALMEYWVPGVGVTGVHELVGNALVMKGEKERTTNLRGEPLPGKEGAVDGDV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCEEEECCCHHHHCCCCCCCCCCCCCCCCCCC
S
C
>Mature Secondary Structure 
AAIPKPEELVKINYRPPRTGWMDTPVQFRRGNYLYAAKPKSLEVVGLPNPREWSPEDED
CCCCCCHHEEEEECCCCCCCCCCCCHHCCCCCEEEEECCCCEEEEECCCCCCCCCCCCC
WKLPENWQEIILEGLRERLGRFRSLQVFMDICVRCGACADKCHFFIGTGDPKNMPVLRAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHH
LLRSVYRRDFTTAGKLLGRLVGARDLTVDVLKEWFYYFFQCTECRRCSLFCPYGIDTAEI
HHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHH
TMIGRELLNLVGCNIDWIASPVANCYRTGNHVGIEPHAFKDMVEFCVDEIENITGIRVEP
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECC
TFNRKGAEVLFIAPSGDVFADPGTYTLMGYLMLFHEIGLDYTWSTYASEGGNFGMFTSHE
CCCCCCCEEEEEECCCCCEECCCHHHHHHHHHHHHHHCCCCEEHHHHCCCCCCCCCCHHH
MMKRLNAKMYAEAKRLGVKWILGGECGHMWRVINQYMDTMNGPADFLEVPVSPITGTRFE
HHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCC
NAKSTKMVHITEFTADLIKHNKLKLDPSRNDNLRVTFHDSCNPARSMGLFEEPRYIIKHV
CCCCCEEEEEHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCHHHHCCCCCCCHHHHHHH
CNNFFEMPENTIREKTFCCGSGAGLNADEYMEMRMRGGLPRANAVKYVHEKYGVNMLACI
HHHHHHCCHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHH
CAVDRAVFPALMEYWVPGVGVTGVHELVGNALVMKGEKERTTNLRGEPLPGKEGAVDGDV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCEEEECCCHHHHCCCCCCCCCCCCCCCCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475; 11952791 [H]