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The map label for this gene is aroQ

Identifier: 83590383

GI number: 83590383

Start: 1583487

End: 1583957

Strand: Reverse

Name: aroQ

Synonym: Moth_1540

Alternate gene names: 83590383

Gene position: 1583957-1583487 (Counterclockwise)

Preceding gene: 83590384

Following gene: 83590382

Centisome position: 60.25

GC content: 63.06

Gene sequence:

>471_bases
ATGAAGATTCTAGTTATAAACGGGCCCAACCTGAACCTCTTAGGTAACCGGGAACCGGAGACCTATGGCCGGACCACCCT
GGCGACCATCGAGGCGGAACTGCGGCGGCAGGCCAGCCAGGCCGGGGTGGAAATCGAGTTCTTCCAGTCCAACCATGAGG
GAGCCCTCATCGACTGCTTACACGCCGCCCGGGGCCGGGTGGATGCCGCGGTCATTAACCCCGGGGCCCTGGGTCATTAC
AGTATCGCCCTGCGGGACGCCCTTGCGGCGGTAGATTACCCGGCAGTGGAGGTCCACCTGTCCAACATCTACCGCCGGGA
AGAGTTCCGCCACCACACGGTGACGGCAGCAGTAGTGGCCGGCCAGATCAGTGGCTTCGGTCCATTAAGCTATCGTCTAG
GGCTGGAAGCAGCCATCGAACTGGCCCGCCGGCGCCGGGAAGCCCCTCCTGACGGTGGGTCTAATGGCTAA

Upstream 100 bases:

>100_bases
ACCATCCGGATCGCCAGCATGACCATCAGCGGCTAAAGGAAAAAGTAATTTATAAAGCAGGACCTACCTAAACGAGCAAT
ATTATGGTAAAATAGCAGCC

Downstream 100 bases:

>100_bases
GCCAGCGCCCGTAGGGAAGAACCTGCCTCATCCTGGAGGTAATGACACCCACTTTTGGTAGAACCTTATTGCCGGAGGAG
GAGTTTATTGTCCAGCAGAT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKILVINGPNLNLLGNREPETYGRTTLATIEAELRRQASQAGVEIEFFQSNHEGALIDCLHAARGRVDAAVINPGALGHY
SIALRDALAAVDYPAVEVHLSNIYRREEFRHHTVTAAVVAGQISGFGPLSYRLGLEAAIELARRRREAPPDGGSNG

Sequences:

>Translated_156_residues
MKILVINGPNLNLLGNREPETYGRTTLATIEAELRRQASQAGVEIEFFQSNHEGALIDCLHAARGRVDAAVINPGALGHY
SIALRDALAAVDYPAVEVHLSNIYRREEFRHHTVTAAVVAGQISGFGPLSYRLGLEAAIELARRRREAPPDGGSNG
>Mature_156_residues
MKILVINGPNLNLLGNREPETYGRTTLATIEAELRRQASQAGVEIEFFQSNHEGALIDCLHAARGRVDAAVINPGALGHY
SIALRDALAAVDYPAVEVHLSNIYRREEFRHHTVTAAVVAGQISGFGPLSYRLGLEAAIELARRRREAPPDGGSNG

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_MOOTA (Q2RI90)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430392.1
- HSSP:   Q48255
- ProteinModelPortal:   Q2RI90
- SMR:   Q2RI90
- STRING:   Q2RI90
- GeneID:   3831926
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1540
- NMPDR:   fig|264732.9.peg.1545
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   HSYIAPI
- ProtClustDB:   PRK05395
- BioCyc:   MTHE264732:MOTH_1540-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16879; Mature: 16879

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 22-22 ACT_SITE 99-99 BINDING 73-73 BINDING 79-79 BINDING 86-86 BINDING 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVINGPNLNLLGNREPETYGRTTLATIEAELRRQASQAGVEIEFFQSNHEGALIDCL
CEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
HAARGRVDAAVINPGALGHYSIALRDALAAVDYPAVEVHLSNIYRREEFRHHTVTAAVVA
HHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
GQISGFGPLSYRLGLEAAIELARRRREAPPDGGSNG
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKILVINGPNLNLLGNREPETYGRTTLATIEAELRRQASQAGVEIEFFQSNHEGALIDCL
CEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
HAARGRVDAAVINPGALGHYSIALRDALAAVDYPAVEVHLSNIYRREEFRHHTVTAAVVA
HHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
GQISGFGPLSYRLGLEAAIELARRRREAPPDGGSNG
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA