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The map label for this gene is efp

Identifier: 83590381

GI number: 83590381

Start: 1581673

End: 1582230

Strand: Reverse

Name: efp

Synonym: Moth_1538

Alternate gene names: 83590381

Gene position: 1582230-1581673 (Counterclockwise)

Preceding gene: 83590382

Following gene: 83590380

Centisome position: 60.19

GC content: 54.84

Gene sequence:

>558_bases
TTGATTTCCACCAACGATTTCCGGACTGGTCTTACCATTGAAGTTGACGGCGACGTCTACACGGTGGTCGAGTTTATGCA
CGTTAAACCCGGCAAGGGGTCGGCCTTCGTCCGCACCAAATTGAAAAACCGGCGCACCGGAGCCGTCATCGAACGTACCT
TCCGCGCCGGGGAAAAGGTCAACCGGGCCCATGTCGAACGGCGGGAGATGCAGTACCTTTATAACGACGGCGATAACTAC
TACTTTATGGACACCGAGACCTTTGAGCAGTTATCCCTGCGGAAAGAGCAACTGGAAGACGCTATTAAGTACCTGAAGGA
TAACATGAACATCTTCGTCCTTACTTACAACGGGGAGACCATTGGCATCGAACTGCCAAACTCTGTGGAGCTGAAGGTCG
TGGAAACGGAGCCTGGCATCAAGGGCGATACGGCCACTGGCGGTACCAAGAACGCCGTCCTGGAAACCGGGGCCGTCATC
CAGGTACCCCTCTTTATCGAAACGGGAGATGTCGTGCGCATCGACACCCGTACCGGCGAGTATATCGAGCGGGCTTAG

Upstream 100 bases:

>100_bases
TTGAGCTGTGAGGGCCGGTAGCCTGCATGGCGGCGGTTCGACAATAGCGAAAAGGGAAAAGCGGGGGCAAGGAGATATTT
TTTTGTAGGAGGTATTGTGT

Downstream 100 bases:

>100_bases
TTTAAGGCCGGCCAGGGCTGGCAATAATAAAAGGGTGGAAGGAAAGGAGTGGCCAGGATGAAAGACCTGCGGAAACAGGT
AGCTTACCTCCAGGGGTTGA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MISTNDFRTGLTIEVDGDVYTVVEFMHVKPGKGSAFVRTKLKNRRTGAVIERTFRAGEKVNRAHVERREMQYLYNDGDNY
YFMDTETFEQLSLRKEQLEDAIKYLKDNMNIFVLTYNGETIGIELPNSVELKVVETEPGIKGDTATGGTKNAVLETGAVI
QVPLFIETGDVVRIDTRTGEYIERA

Sequences:

>Translated_185_residues
MISTNDFRTGLTIEVDGDVYTVVEFMHVKPGKGSAFVRTKLKNRRTGAVIERTFRAGEKVNRAHVERREMQYLYNDGDNY
YFMDTETFEQLSLRKEQLEDAIKYLKDNMNIFVLTYNGETIGIELPNSVELKVVETEPGIKGDTATGGTKNAVLETGAVI
QVPLFIETGDVVRIDTRTGEYIERA
>Mature_185_residues
MISTNDFRTGLTIEVDGDVYTVVEFMHVKPGKGSAFVRTKLKNRRTGAVIERTFRAGEKVNRAHVERREMQYLYNDGDNY
YFMDTETFEQLSLRKEQLEDAIKYLKDNMNIFVLTYNGETIGIELPNSVELKVVETEPGIKGDTATGGTKNAVLETGAVI
QVPLFIETGDVVRIDTRTGEYIERA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=181, Percent_Identity=48.0662983425414, Blast_Score=185, Evalue=2e-48,
Organism=Escherichia coli, GI87082061, Length=189, Percent_Identity=32.2751322751323, Blast_Score=112, Evalue=1e-26,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_MOOTA (Q2RI92)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430390.1
- ProteinModelPortal:   Q2RI92
- SMR:   Q2RI92
- STRING:   Q2RI92
- GeneID:   3831924
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1538
- NMPDR:   fig|264732.9.peg.1543
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q2RI92
- ProtClustDB:   PRK00529
- BioCyc:   MTHE264732:MOTH_1538-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20955; Mature: 20955

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTNDFRTGLTIEVDGDVYTVVEFMHVKPGKGSAFVRTKLKNRRTGAVIERTFRAGEKV
CCCCCCCCCCEEEEECCCEEEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHCCCHH
NRAHVERREMQYLYNDGDNYYFMDTETFEQLSLRKEQLEDAIKYLKDNMNIFVLTYNGET
HHHHHHHHHHHEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCE
IGIELPNSVELKVVETEPGIKGDTATGGTKNAVLETGAVIQVPLFIETGDVVRIDTRTGE
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCEEEEEEEEECCCEEEEECCCCC
YIERA
HHHCC
>Mature Secondary Structure
MISTNDFRTGLTIEVDGDVYTVVEFMHVKPGKGSAFVRTKLKNRRTGAVIERTFRAGEKV
CCCCCCCCCCEEEEECCCEEEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHCCCHH
NRAHVERREMQYLYNDGDNYYFMDTETFEQLSLRKEQLEDAIKYLKDNMNIFVLTYNGET
HHHHHHHHHHHEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCE
IGIELPNSVELKVVETEPGIKGDTATGGTKNAVLETGAVIQVPLFIETGDVVRIDTRTGE
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCEEEEEEEEECCCEEEEECCCCC
YIERA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA