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The map label for this gene is ytnA [H]

Identifier: 83590371

GI number: 83590371

Start: 1573421

End: 1574818

Strand: Reverse

Name: ytnA [H]

Synonym: Moth_1528

Alternate gene names: 83590371

Gene position: 1574818-1573421 (Counterclockwise)

Preceding gene: 83590372

Following gene: 83590370

Centisome position: 59.91

GC content: 58.66

Gene sequence:

>1398_bases
TTGACAGGCGGTAAAGGCGAAGAACGCCGGAAAAACCTGAGTGCCTTTAGCTTGATCTTCCTTGGCCTCGGTTCAACTAT
AGGCAGCAGCTTTTTCCTGGCTTCCGGGATGGCCATCCGGGCCGCCGGGCCGGCAGTCATCCTGGGGTATATTTTTAGCG
GCTTCGTATTTTACCTGGTACTGGTATCCCTGGGTCACCTGGCCCTGAAATACAGACAGAGGGAATCCGTACGCGGTTAT
GTGGAAGAAGCCCTCGGGCCCACGGGAGCCTTTATAACCGGCTGGAATCTATGGCTAACCAGCCTGGTGGGCATGGTGAG
CGAGGCCGTGGCTATGGCCATTTACACCCGTTTCTGGTTTCCCTGGCTGCCAATCTGGATCCTGGTCATGGCTTATGGTT
TTCTGGTGGCGGGGATCAACTATTTTGGCGTTGACATCGTAGATAAATTTGAAGGCGGGCTGACGGTTATCAAGGCGGGG
AGCGTCCTGGCCTTCACCGGCGTGATGCTGTATATAGTCCTTGCTAGAAGGATCGCGGTGGCGGCGACCGGTTTACTGCC
ATTCTTTCCCAACGGCTTAAGGGGTTTAAGCCAGGCCATTGTCGTCACTACCTTTGCCTATGGCGCCGGGGCCCTGGCCG
CGGCCGTGGGCGATACTCGAAACCCGCGCCGGGCCGTACCTCTGGCGACTGCCGGAATGGCCCTGGCCCAGGCCCTTTTT
TTCCTGCTGCCGGTTACCGCCCTGGTGGCTGTTACGCCCTGGTTTCTGATCAGCAGCCAGTCCAGCCCCTTTGTAACCGG
TCTGGAACACGCCGGTATCCGCCTTGGCGGCTCAGTGCTAAACGCCATTGTCCTGGTCGCCTCCTCTTCGGTTTTGTTGG
GGTCAATGTTTACGGCCGTAACTATGCTGGCTTCCCTGGCCCGGGACAGGGAAGCCCCGGCGTTCTTGATTGCCGGCGAA
GGAGAAAAGCCGGTAAAGGCCCTCGTAGTGACGGCGGGGGTGATGCTCCTGGTATCCTTGCTGGCTATCTTCTTACCCCG
CCATATCTACCAGTATGCCGTAACGGCTACCGGTTACTTCAGCTTTGTTAACTGGGGGGCCATCCTGGCAGCCCGCCTGT
ACCTCTCCCTGCCGATCAAAAATGAAGGCCGCCTGGATACGAAAGGGTTAGTCGTTGCAGGGGCAGGGCTGGCCGGCCTG
ACAGCCATATCCCTTTTAGGATTGACCATGCCGGAGCAGAGGTTCTCCCTGCTGGTAATGGTCGCCAGCACCCTGATTCT
GCTGGGTATAGGTATTTTGGTGAAGAGGGAGAAGCTGGCCCCGGAGGCAGGTAACAGGGAGGAAGCAGCCGGCTGGCTGG
AGCGACTCCTGGGTGGCCCCGGGCGCAACCCGGTTTAG

Upstream 100 bases:

>100_bases
GAAAAAACTAGACCTGGGGCCTGAGCCTTCAGGTCCTGTTTTTAACTTCCCCGCTTTCTGAGAACGGTATTTATAAAATA
CTACTACTGGGGGAATTTAT

Downstream 100 bases:

>100_bases
GAATTGAACTTCCATGTATTAAATCTTGCTTTATGATACTATCGTCCATAAAACGGAGAGGGTACGGCGATGGTATGGAG
AGGGTTTGGGGTACCACTTT

Product: amino acid permease-associated region

Products: Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MTGGKGEERRKNLSAFSLIFLGLGSTIGSSFFLASGMAIRAAGPAVILGYIFSGFVFYLVLVSLGHLALKYRQRESVRGY
VEEALGPTGAFITGWNLWLTSLVGMVSEAVAMAIYTRFWFPWLPIWILVMAYGFLVAGINYFGVDIVDKFEGGLTVIKAG
SVLAFTGVMLYIVLARRIAVAATGLLPFFPNGLRGLSQAIVVTTFAYGAGALAAAVGDTRNPRRAVPLATAGMALAQALF
FLLPVTALVAVTPWFLISSQSSPFVTGLEHAGIRLGGSVLNAIVLVASSSVLLGSMFTAVTMLASLARDREAPAFLIAGE
GEKPVKALVVTAGVMLLVSLLAIFLPRHIYQYAVTATGYFSFVNWGAILAARLYLSLPIKNEGRLDTKGLVVAGAGLAGL
TAISLLGLTMPEQRFSLLVMVASTLILLGIGILVKREKLAPEAGNREEAAGWLERLLGGPGRNPV

Sequences:

>Translated_465_residues
MTGGKGEERRKNLSAFSLIFLGLGSTIGSSFFLASGMAIRAAGPAVILGYIFSGFVFYLVLVSLGHLALKYRQRESVRGY
VEEALGPTGAFITGWNLWLTSLVGMVSEAVAMAIYTRFWFPWLPIWILVMAYGFLVAGINYFGVDIVDKFEGGLTVIKAG
SVLAFTGVMLYIVLARRIAVAATGLLPFFPNGLRGLSQAIVVTTFAYGAGALAAAVGDTRNPRRAVPLATAGMALAQALF
FLLPVTALVAVTPWFLISSQSSPFVTGLEHAGIRLGGSVLNAIVLVASSSVLLGSMFTAVTMLASLARDREAPAFLIAGE
GEKPVKALVVTAGVMLLVSLLAIFLPRHIYQYAVTATGYFSFVNWGAILAARLYLSLPIKNEGRLDTKGLVVAGAGLAGL
TAISLLGLTMPEQRFSLLVMVASTLILLGIGILVKREKLAPEAGNREEAAGWLERLLGGPGRNPV
>Mature_464_residues
TGGKGEERRKNLSAFSLIFLGLGSTIGSSFFLASGMAIRAAGPAVILGYIFSGFVFYLVLVSLGHLALKYRQRESVRGYV
EEALGPTGAFITGWNLWLTSLVGMVSEAVAMAIYTRFWFPWLPIWILVMAYGFLVAGINYFGVDIVDKFEGGLTVIKAGS
VLAFTGVMLYIVLARRIAVAATGLLPFFPNGLRGLSQAIVVTTFAYGAGALAAAVGDTRNPRRAVPLATAGMALAQALFF
LLPVTALVAVTPWFLISSQSSPFVTGLEHAGIRLGGSVLNAIVLVASSSVLLGSMFTAVTMLASLARDREAPAFLIAGEG
EKPVKALVVTAGVMLLVSLLAIFLPRHIYQYAVTATGYFSFVNWGAILAARLYLSLPIKNEGRLDTKGLVVAGAGLAGLT
AISLLGLTMPEQRFSLLVMVASTLILLGIGILVKREKLAPEAGNREEAAGWLERLLGGPGRNPV

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of Phenylalanine. [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786789, Length=424, Percent_Identity=28.5377358490566, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786602, Length=455, Percent_Identity=27.2527472527473, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1786302, Length=444, Percent_Identity=25.4504504504505, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1790653, Length=342, Percent_Identity=26.9005847953216, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1789017, Length=399, Percent_Identity=24.5614035087719, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI87081708, Length=396, Percent_Identity=25.5050505050505, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI87081915, Length=389, Percent_Identity=25.706940874036, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI48994972, Length=378, Percent_Identity=25.6613756613757, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788480, Length=378, Percent_Identity=27.2486772486773, Blast_Score=112, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17532491, Length=363, Percent_Identity=23.4159779614325, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320717, Length=411, Percent_Identity=23.3576642335766, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6319824, Length=411, Percent_Identity=22.6277372262774, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320251, Length=410, Percent_Identity=20.4878048780488, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320772, Length=406, Percent_Identity=22.6600985221675, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324990, Length=432, Percent_Identity=23.6111111111111, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6319542, Length=410, Percent_Identity=21.9512195121951, Blast_Score=73, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324061, Length=364, Percent_Identity=22.8021978021978, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322892, Length=400, Percent_Identity=22.25, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324553, Length=405, Percent_Identity=22.962962962963, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324059, Length=299, Percent_Identity=23.0769230769231, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321053, Length=411, Percent_Identity=24.8175182481752, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49153; Mature: 49022

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGGKGEERRKNLSAFSLIFLGLGSTIGSSFFLASGMAIRAAGPAVILGYIFSGFVFYLV
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEECCCHHHHHHHHHHHHHHHHH
LVSLGHLALKYRQRESVRGYVEEALGPTGAFITGWNLWLTSLVGMVSEAVAMAIYTRFWF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PWLPIWILVMAYGFLVAGINYFGVDIVDKFEGGLTVIKAGSVLAFTGVMLYIVLARRIAV
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
AATGLLPFFPNGLRGLSQAIVVTTFAYGAGALAAAVGDTRNPRRAVPLATAGMALAQALF
HHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
FLLPVTALVAVTPWFLISSQSSPFVTGLEHAGIRLGGSVLNAIVLVASSSVLLGSMFTAV
HHHHHHHHHHHHHHHEEECCCCCCEECHHHCCCEECHHHHHHHHHHHCCHHHHHHHHHHH
TMLASLARDREAPAFLIAGEGEKPVKALVVTAGVMLLVSLLAIFLPRHIYQYAVTATGYF
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFVNWGAILAARLYLSLPIKNEGRLDTKGLVVAGAGLAGLTAISLLGLTMPEQRFSLLVM
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHH
VASTLILLGIGILVKREKLAPEAGNREEAAGWLERLLGGPGRNPV
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TGGKGEERRKNLSAFSLIFLGLGSTIGSSFFLASGMAIRAAGPAVILGYIFSGFVFYLV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEECCCHHHHHHHHHHHHHHHHH
LVSLGHLALKYRQRESVRGYVEEALGPTGAFITGWNLWLTSLVGMVSEAVAMAIYTRFWF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PWLPIWILVMAYGFLVAGINYFGVDIVDKFEGGLTVIKAGSVLAFTGVMLYIVLARRIAV
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
AATGLLPFFPNGLRGLSQAIVVTTFAYGAGALAAAVGDTRNPRRAVPLATAGMALAQALF
HHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
FLLPVTALVAVTPWFLISSQSSPFVTGLEHAGIRLGGSVLNAIVLVASSSVLLGSMFTAV
HHHHHHHHHHHHHHHEEECCCCCCEECHHHCCCEECHHHHHHHHHHHCCHHHHHHHHHHH
TMLASLARDREAPAFLIAGEGEKPVKALVVTAGVMLLVSLLAIFLPRHIYQYAVTATGYF
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFVNWGAILAARLYLSLPIKNEGRLDTKGLVVAGAGLAGLTAISLLGLTMPEQRFSLLVM
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHH
VASTLILLGIGILVKREKLAPEAGNREEAAGWLERLLGGPGRNPV
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] + L-phenylalanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]