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The map label for this gene is ftsY [H]

Identifier: 83592517

GI number: 83592517

Start: 1398034

End: 1399554

Strand: Reverse

Name: ftsY [H]

Synonym: Rru_A1181

Alternate gene names: 83592517

Gene position: 1399554-1398034 (Counterclockwise)

Preceding gene: 83592518

Following gene: 83592511

Centisome position: 32.15

GC content: 69.49

Gene sequence:

>1521_bases
GTGAGCGAGCACAGCGCCAATCAGCGGAAGAAGAAGGGCACCGCCGTGGCGGTCCCGACGTCCCTCGAAAGCCGGCCCCG
CCGTCGCATCGACCCGCTCGCCCATAAGAAGCGGGGCTTCTGGAGCACGCTTTTCTGGACCATCGTCGGCCCGGTGTCGT
TCGATGTGGCCGAAGCCGAACTGGCCGCCGCCGAGCAGGCCGAACTCGCCGCCCTCGCCCCGCCCGCCGCCGCGCCCCCC
ACCACGCCCAAGCGCCCGCTCAGCGCCCCGCCGCCGCTGGCCAAGCCCCGGCCCGAGGCGAGGCCGACGCCGCCCAAGCC
GGTCGTCGTGCCGAGCGCCAAGCCCGAGCCCAAGCCGGTCGCGGTTCCGCCGCCCGCCGCCAAGCCGCCCGTCGCCAAGC
CGTCCATTCCCAAGCCGGCTCCGCCGCCGCCGGTGCCACCCACCGCCCCGCCGCCGGCGACCGCGCCCGAGGCCCTCGTT
CCCGAGAGCCTGCCCGAGGTCATCGCCCCGCAGATCACGCCCGAGGCGGCGCCGCCGGTCGTTCCCGAAGCCATCCCCGA
GTTCTGGCCGGAGGTTCTTCCAGAACCAGTGGCCGAGCCGGTCAAGGTCAGCTTCTTCGCCCGGCTGCGCGGCGGTCTGT
CGCGGACCTCGGGCAAGCTGGTTGGCGGCATCATGGGGCTGGTCAGCGAGCGCAAGCTCGATGATCAGGCGCTCGAGGAT
CTGGAAGACCTGCTGATCACCGCCGATATCGGCGTCGAGACCGCGGGCAAGCTGACGCGCTCGCTGGCCAAGGAACGCTT
TGGCAAGAACGTGACCGGCGAAGAGATTCGCGGCCATTTCGCCGACGAGATCGCCACCATCCTCGGCCCTGTCGCCCGGC
CGCTCGAAATCGACGGGTCGCTCAAGCCCCATGTCGTCCTGGTGGTCGGCGTCAACGGCTCGGGCAAGACCACGACGATC
GGCAAGATCGCCAACCAGTTGGTGCACGAGAACAAAAGGGTGCTGCTGGCCGCCGGCGACACCTTCCGCGCCGCCGCCGT
CGAACAACTGCGCATCTGGGGGGATCGCACCGGCTGCGAGGTGATCGCCCGCGACACCGGCGCCGATTCCGCCGGCCTCG
CTTTCGACGCCCTGCAAAAGGCGCGGGCCGAGGGCTACGACGTGCTGCTGATCGATACCGCCGGCCGCTTGCACAACAAG
ACCGAGCTGATGGAGGAACTGAAAAAGGTCGTGCGCGTGCTGCGCAAGATCGATCCGGCGGTTCCCCATACCTGTCTCCA
GGTCCTCGACGCCACCGTCGGCCAAAACGCCCACCAGCAGGTCAAGGTCTTCCAGGAGATGACCGATGTCTCGGGACTGG
TGATGACCAAGCTCGACGGCACGGCCAAGGGCGGCGTGGTGGTGGCGCTTGCCGATAAATTCGGCCTGCCCGTCCATTAC
GTCGGCATCGGCGAAGGCATCGATGATCTGCGCCCCTTCAGCGCGCGGGACTTCGCCCGCGGGCTGATGGACCTCGATTA
G

Upstream 100 bases:

>100_bases
TTGTCCCCGTGAGCGTGGACCCGGCCCTGACGCCGGGCAGCATCGTGCCCGTCCGGCTGCGCGCCGGTGAGGGTGGCCAT
CTGATCGGAGAAGCCGTTTC

Downstream 100 bases:

>100_bases
AGCAAATCCCGAGCACTCTGTTCCAGAGTGCGACGACGATTTGCTTCAATATCAGTGGGTTAGAGCTGCGTTCCGGTACC
AGATGTCACGCACGCAGCTC

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MSEHSANQRKKKGTAVAVPTSLESRPRRRIDPLAHKKRGFWSTLFWTIVGPVSFDVAEAELAAAEQAELAALAPPAAAPP
TTPKRPLSAPPPLAKPRPEARPTPPKPVVVPSAKPEPKPVAVPPPAAKPPVAKPSIPKPAPPPPVPPTAPPPATAPEALV
PESLPEVIAPQITPEAAPPVVPEAIPEFWPEVLPEPVAEPVKVSFFARLRGGLSRTSGKLVGGIMGLVSERKLDDQALED
LEDLLITADIGVETAGKLTRSLAKERFGKNVTGEEIRGHFADEIATILGPVARPLEIDGSLKPHVVLVVGVNGSGKTTTI
GKIANQLVHENKRVLLAAGDTFRAAAVEQLRIWGDRTGCEVIARDTGADSAGLAFDALQKARAEGYDVLLIDTAGRLHNK
TELMEELKKVVRVLRKIDPAVPHTCLQVLDATVGQNAHQQVKVFQEMTDVSGLVMTKLDGTAKGGVVVALADKFGLPVHY
VGIGEGIDDLRPFSARDFARGLMDLD

Sequences:

>Translated_506_residues
MSEHSANQRKKKGTAVAVPTSLESRPRRRIDPLAHKKRGFWSTLFWTIVGPVSFDVAEAELAAAEQAELAALAPPAAAPP
TTPKRPLSAPPPLAKPRPEARPTPPKPVVVPSAKPEPKPVAVPPPAAKPPVAKPSIPKPAPPPPVPPTAPPPATAPEALV
PESLPEVIAPQITPEAAPPVVPEAIPEFWPEVLPEPVAEPVKVSFFARLRGGLSRTSGKLVGGIMGLVSERKLDDQALED
LEDLLITADIGVETAGKLTRSLAKERFGKNVTGEEIRGHFADEIATILGPVARPLEIDGSLKPHVVLVVGVNGSGKTTTI
GKIANQLVHENKRVLLAAGDTFRAAAVEQLRIWGDRTGCEVIARDTGADSAGLAFDALQKARAEGYDVLLIDTAGRLHNK
TELMEELKKVVRVLRKIDPAVPHTCLQVLDATVGQNAHQQVKVFQEMTDVSGLVMTKLDGTAKGGVVVALADKFGLPVHY
VGIGEGIDDLRPFSARDFARGLMDLD
>Mature_505_residues
SEHSANQRKKKGTAVAVPTSLESRPRRRIDPLAHKKRGFWSTLFWTIVGPVSFDVAEAELAAAEQAELAALAPPAAAPPT
TPKRPLSAPPPLAKPRPEARPTPPKPVVVPSAKPEPKPVAVPPPAAKPPVAKPSIPKPAPPPPVPPTAPPPATAPEALVP
ESLPEVIAPQITPEAAPPVVPEAIPEFWPEVLPEPVAEPVKVSFFARLRGGLSRTSGKLVGGIMGLVSERKLDDQALEDL
EDLLITADIGVETAGKLTRSLAKERFGKNVTGEEIRGHFADEIATILGPVARPLEIDGSLKPHVVLVVGVNGSGKTTTIG
KIANQLVHENKRVLLAAGDTFRAAAVEQLRIWGDRTGCEVIARDTGADSAGLAFDALQKARAEGYDVLLIDTAGRLHNKT
ELMEELKKVVRVLRKIDPAVPHTCLQVLDATVGQNAHQQVKVFQEMTDVSGLVMTKLDGTAKGGVVVALADKFGLPVHYV
GIGEGIDDLRPFSARDFARGLMDLD

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI295424842, Length=327, Percent_Identity=31.1926605504587, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI23308697, Length=327, Percent_Identity=31.1926605504587, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI226371618, Length=204, Percent_Identity=32.3529411764706, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4507215, Length=204, Percent_Identity=32.3529411764706, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI89061728, Length=140, Percent_Identity=31.4285714285714, Blast_Score=90, Evalue=5e-18,
Organism=Escherichia coli, GI1789874, Length=325, Percent_Identity=49.8461538461538, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1788963, Length=295, Percent_Identity=31.5254237288136, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI193206261, Length=323, Percent_Identity=33.1269349845201, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17539958, Length=285, Percent_Identity=28.0701754385965, Blast_Score=111, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6325345, Length=285, Percent_Identity=29.1228070175439, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320498, Length=345, Percent_Identity=29.5652173913043, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24641198, Length=330, Percent_Identity=31.8181818181818, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI17647949, Length=224, Percent_Identity=33.0357142857143, Blast_Score=122, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 53669; Mature: 53537

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHSANQRKKKGTAVAVPTSLESRPRRRIDPLAHKKRGFWSTLFWTIVGPVSFDVAEAE
CCCCCCHHHHHCCCEEEECCCCCCCCHHHCCHHHHHHCCHHHHHHHHHHCCCCCCHHHHH
LAAAEQAELAALAPPAAAPPTTPKRPLSAPPPLAKPRPEARPTPPKPVVVPSAKPEPKPV
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCC
AVPPPAAKPPVAKPSIPKPAPPPPVPPTAPPPATAPEALVPESLPEVIAPQITPEAAPPV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHCCCCCCCCCCCC
VPEAIPEFWPEVLPEPVAEPVKVSFFARLRGGLSRTSGKLVGGIMGLVSERKLDDQALED
CHHHHHHHHHHHCCCHHCCCHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCHHHHHH
LEDLLITADIGVETAGKLTRSLAKERFGKNVTGEEIRGHFADEIATILGPVARPLEIDGS
HHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEECCCC
LKPHVVLVVGVNGSGKTTTIGKIANQLVHENKRVLLAAGDTFRAAAVEQLRIWGDRTGCE
CCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCE
VIARDTGADSAGLAFDALQKARAEGYDVLLIDTAGRLHNKTELMEELKKVVRVLRKIDPA
EEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHHHCCC
VPHTCLQVLDATVGQNAHQQVKVFQEMTDVSGLVMTKLDGTAKGGVVVALADKFGLPVHY
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCCEEE
VGIGEGIDDLRPFSARDFARGLMDLD
EECCCCHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SEHSANQRKKKGTAVAVPTSLESRPRRRIDPLAHKKRGFWSTLFWTIVGPVSFDVAEAE
CCCCCHHHHHCCCEEEECCCCCCCCHHHCCHHHHHHCCHHHHHHHHHHCCCCCCHHHHH
LAAAEQAELAALAPPAAAPPTTPKRPLSAPPPLAKPRPEARPTPPKPVVVPSAKPEPKPV
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCC
AVPPPAAKPPVAKPSIPKPAPPPPVPPTAPPPATAPEALVPESLPEVIAPQITPEAAPPV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHCCCCCCCCCCCC
VPEAIPEFWPEVLPEPVAEPVKVSFFARLRGGLSRTSGKLVGGIMGLVSERKLDDQALED
CHHHHHHHHHHHCCCHHCCCHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCHHHHHH
LEDLLITADIGVETAGKLTRSLAKERFGKNVTGEEIRGHFADEIATILGPVARPLEIDGS
HHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEECCCC
LKPHVVLVVGVNGSGKTTTIGKIANQLVHENKRVLLAAGDTFRAAAVEQLRIWGDRTGCE
CCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCE
VIARDTGADSAGLAFDALQKARAEGYDVLLIDTAGRLHNKTELMEELKKVVRVLRKIDPA
EEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHHHCCC
VPHTCLQVLDATVGQNAHQQVKVFQEMTDVSGLVMTKLDGTAKGGVVVALADKFGLPVHY
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCCEEE
VGIGEGIDDLRPFSARDFARGLMDLD
EECCCCHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]