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The map label for this gene is gcvT

Identifier: 82751141

GI number: 82751141

Start: 1530879

End: 1531970

Strand: Reverse

Name: gcvT

Synonym: SAB1409c

Alternate gene names: 82751141

Gene position: 1531970-1530879 (Counterclockwise)

Preceding gene: 82751142

Following gene: 82751140

Centisome position: 55.86

GC content: 31.59

Gene sequence:

>1092_bases
ATGTCAAGTGATTTAAAACAAACACCTTTATATCAAAATTATGTTGATAGAGGTGCAAAAATTGTGGAATTCGGAGGATG
GGCGATGCCTGTTCAATTTTCAAGTATTAAAGAGGAGCATAATGCTGCTCGATACGAAATTGGCCTGTTTGATGTTAGTC
ATATGGGTGAAATTGAAGTAACAGGTAAAGATGCTAGTCAGTTTGTGCAATATTTATTATCAAATGATACTGATAATTTA
ACTACTTCAAAAGCATTATATACTGCTTTATGTAATGAAGAAGGCGGTGTTATTGATGATTTAGTAATATATAAATTAGC
TGACGACAATTATTTATTAGTCGTTAATGCTGCTAATACTGAAAAAGATTTTAATTGGATTTTAAAACACAAAGAGAAAT
TTGATGTTGAAGTACAAAATGTATCAAACCAATATGGTCAATTAGCAATACAAGGACCAAAAGCTAGAGATTTAATTAAT
CAATTAGTTGATGAAGATGTAACTGAAATGAAAATGTTTGAATTTAAACAGGGTGTCAAATTATTTGCAGCAAACGTCAT
TTTATCTCAGTCAGGTTACACAGGTGAAGATGGGTTTGAAATTTATTGTAATATCGATGATACTGAAAAAATTTGGGATG
GTTTATTAGAGTATAATGTTATGCCATGTGGGTTAGGCGCTCGTGATACATTAAGATTAGAGGCTGGATTGCCATTACAT
GGACAAGATTTAACTGAATCAATTACACCATATGAAGGTGGTATCGCTTTTGCAAGTAAACCATTAATTGATGCTGATTT
TATTGGTAAATCTGTATTAAAAGATCAAAAAGAAAATGGTGCACCAAGAAGAACAGTGGGATTAGAATTACTTGAAAAAG
GAATTGCAAGAACTGGTTATGAAGTTATGGATTTAGATGGAAATATTATTGGAGAAGTAACTTCAGGAACACAGTCTCCA
TCATCAGGAAAATCAATTGCACTTGCAATGATAAAAAGAGATGAGTTTGAAATGGGTAGAGAGTTGCTTGTTCAAGTTCG
TAAGCGTCAATTAAAAGCGAAAATTGTTAAGAAAAATCAAATTGATAAATAA

Upstream 100 bases:

>100_bases
TCAGGTAAAAGGATAATACTGTAACGCGTTCCTGAATTGGTGATTTATAAACAGGGTAGCGATTGCTATCCTGTTTTTAT
AATTTTAAGGGGGTATTTCA

Downstream 100 bases:

>100_bases
TTAAAAAGGGGTGTGCATTGTGAGTCATCGTTATATACCTTTAACTGAAAAAGACAAGCAAGAAATGTTACAAACAATTG
GTGCAAAATCTATAGGAGAA

Product: glycine cleavage system aminomethyltransferase T

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSSDLKQTPLYQNYVDRGAKIVEFGGWAMPVQFSSIKEEHNAARYEIGLFDVSHMGEIEVTGKDASQFVQYLLSNDTDNL
TTSKALYTALCNEEGGVIDDLVIYKLADDNYLLVVNAANTEKDFNWILKHKEKFDVEVQNVSNQYGQLAIQGPKARDLIN
QLVDEDVTEMKMFEFKQGVKLFAANVILSQSGYTGEDGFEIYCNIDDTEKIWDGLLEYNVMPCGLGARDTLRLEAGLPLH
GQDLTESITPYEGGIAFASKPLIDADFIGKSVLKDQKENGAPRRTVGLELLEKGIARTGYEVMDLDGNIIGEVTSGTQSP
SSGKSIALAMIKRDEFEMGRELLVQVRKRQLKAKIVKKNQIDK

Sequences:

>Translated_363_residues
MSSDLKQTPLYQNYVDRGAKIVEFGGWAMPVQFSSIKEEHNAARYEIGLFDVSHMGEIEVTGKDASQFVQYLLSNDTDNL
TTSKALYTALCNEEGGVIDDLVIYKLADDNYLLVVNAANTEKDFNWILKHKEKFDVEVQNVSNQYGQLAIQGPKARDLIN
QLVDEDVTEMKMFEFKQGVKLFAANVILSQSGYTGEDGFEIYCNIDDTEKIWDGLLEYNVMPCGLGARDTLRLEAGLPLH
GQDLTESITPYEGGIAFASKPLIDADFIGKSVLKDQKENGAPRRTVGLELLEKGIARTGYEVMDLDGNIIGEVTSGTQSP
SSGKSIALAMIKRDEFEMGRELLVQVRKRQLKAKIVKKNQIDK
>Mature_362_residues
SSDLKQTPLYQNYVDRGAKIVEFGGWAMPVQFSSIKEEHNAARYEIGLFDVSHMGEIEVTGKDASQFVQYLLSNDTDNLT
TSKALYTALCNEEGGVIDDLVIYKLADDNYLLVVNAANTEKDFNWILKHKEKFDVEVQNVSNQYGQLAIQGPKARDLINQ
LVDEDVTEMKMFEFKQGVKLFAANVILSQSGYTGEDGFEIYCNIDDTEKIWDGLLEYNVMPCGLGARDTLRLEAGLPLHG
QDLTESITPYEGGIAFASKPLIDADFIGKSVLKDQKENGAPRRTVGLELLEKGIARTGYEVMDLDGNIIGEVTSGTQSPS
SGKSIALAMIKRDEFEMGRELLVQVRKRQLKAKIVKKNQIDK

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=365, Percent_Identity=33.1506849315069, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI257796258, Length=354, Percent_Identity=32.7683615819209, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI257796254, Length=358, Percent_Identity=30.4469273743017, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI257796256, Length=312, Percent_Identity=31.0897435897436, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI24797151, Length=334, Percent_Identity=26.9461077844311, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI197927446, Length=368, Percent_Identity=23.9130434782609, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI21361378, Length=368, Percent_Identity=23.9130434782609, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI194306651, Length=375, Percent_Identity=24, Blast_Score=102, Evalue=8e-22,
Organism=Escherichia coli, GI1789272, Length=362, Percent_Identity=43.0939226519337, Blast_Score=271, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17560118, Length=367, Percent_Identity=36.2397820163488, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI32563613, Length=381, Percent_Identity=25.1968503937008, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI71994052, Length=346, Percent_Identity=25.1445086705202, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71994045, Length=346, Percent_Identity=25.1445086705202, Blast_Score=101, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6320222, Length=385, Percent_Identity=35.0649350649351, Blast_Score=181, Evalue=1e-46,
Organism=Drosophila melanogaster, GI20129441, Length=367, Percent_Identity=33.7874659400545, Blast_Score=198, Evalue=4e-51,
Organism=Drosophila melanogaster, GI28571104, Length=357, Percent_Identity=27.7310924369748, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20130091, Length=331, Percent_Identity=22.9607250755287, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 40430; Mature: 40299

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDLKQTPLYQNYVDRGAKIVEFGGWAMPVQFSSIKEEHNAARYEIGLFDVSHMGEIEV
CCCCCCCCCCHHHHHHCCCEEEEECCEEEEEEHHHHHHHCCCCEEEEEEEEECCCCEEEE
TGKDASQFVQYLLSNDTDNLTTSKALYTALCNEEGGVIDDLVIYKLADDNYLLVVNAANT
ECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEEECCCEEEEEECCCC
EKDFNWILKHKEKFDVEVQNVSNQYGQLAIQGPKARDLINQLVDEDVTEMKMFEFKQGVK
CCHHHHHHHCCHHCCEEHHHHCCCCCEEEECCCHHHHHHHHHHHCHHHHHHHHHHHHHHH
LFAANVILSQSGYTGEDGFEIYCNIDDTEKIWDGLLEYNVMPCGLGARDTLRLEAGLPLH
HHHHHHEEECCCCCCCCCCEEEECCCCHHHHHHHHHHCCCEECCCCCCCEEEEECCCCCC
GQDLTESITPYEGGIAFASKPLIDADFIGKSVLKDQKENGAPRRTVGLELLEKGIARTGY
CCCHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
EVMDLDGNIIGEVTSGTQSPSSGKSIALAMIKRDEFEMGRELLVQVRKRQLKAKIVKKNQ
EEEECCCCEEEEECCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC
IDK
CCC
>Mature Secondary Structure 
SSDLKQTPLYQNYVDRGAKIVEFGGWAMPVQFSSIKEEHNAARYEIGLFDVSHMGEIEV
CCCCCCCCCHHHHHHCCCEEEEECCEEEEEEHHHHHHHCCCCEEEEEEEEECCCCEEEE
TGKDASQFVQYLLSNDTDNLTTSKALYTALCNEEGGVIDDLVIYKLADDNYLLVVNAANT
ECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEEECCCEEEEEECCCC
EKDFNWILKHKEKFDVEVQNVSNQYGQLAIQGPKARDLINQLVDEDVTEMKMFEFKQGVK
CCHHHHHHHCCHHCCEEHHHHCCCCCEEEECCCHHHHHHHHHHHCHHHHHHHHHHHHHHH
LFAANVILSQSGYTGEDGFEIYCNIDDTEKIWDGLLEYNVMPCGLGARDTLRLEAGLPLH
HHHHHHEEECCCCCCCCCCEEEECCCCHHHHHHHHHHCCCEECCCCCCCEEEEECCCCCC
GQDLTESITPYEGGIAFASKPLIDADFIGKSVLKDQKENGAPRRTVGLELLEKGIARTGY
CCCHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
EVMDLDGNIIGEVTSGTQSPSSGKSIALAMIKRDEFEMGRELLVQVRKRQLKAKIVKKNQ
EEEECCCCEEEEECCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC
IDK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA