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The map label for this gene is melR [C]

Identifier: 82750369

GI number: 82750369

Start: 683507

End: 685657

Strand: Direct

Name: melR [C]

Synonym: SAB0616

Alternate gene names: 82750369

Gene position: 683507-685657 (Clockwise)

Preceding gene: 82750368

Following gene: 82750370

Centisome position: 24.92

GC content: 26.82

Gene sequence:

>2151_bases
ATGGCAAAATCATGCTTGCATATACTTACTAATAATGAATATGCGACAACGCGTTGCCAAGATGGCATAGTCTTATTTTG
GCCAATTGACGGGGAAATCGAACTACAAAAATTTCGTAAAAGTAAAATAATTGAAGATGATATATATATTATTAATCATC
TGGATGTATTTAGTATTAAGAATAATAAAAAAACGATCATGTTGTATTTGAGTAGCGATTGGTTTGCGGAATTAGGCTTT
ACTTTCTTTAATTACCACTATACAGCAAAGTTAATTAAATCATCCTATAATTTGAAATGTCTACTATTAAAATTGACTTA
TCGATACCTTGATAATCAACCTCTCAATGACGCTGATGTTAGAAAATTACAGGATATTATTAAAATTATTGCAAAAGAAG
CAAGTATGGATAAAAAGATTGCGCAAAATCAATATCGATATGCCTATTATGGTGATTTGCGTGACGAGCTCGAATATATT
TATCAAAATGTAAATCAACGATTGACATTAAAAAGTGTCGCTGATAAATTATTTGTCTCAAAGTCAAATTTGTCATCACA
ATTCCACTTACTTATGGGCATGGGTTTTAAAAAATATATTGATACTTTGAAAATTGGTAAATCGATTGAAATTCTACTTA
CTACTGATAGTACTATTAGCAACATAAGTGAACATTTAGGTTTTAGTAGTAGCTCAACTTACTCTAAAATGTTTAAAAGT
TATATGGATATAACACCGAATGAATATCGTAATTTATCAAAATATAATAAATGTTTAATGCTAAAGCCAGAATCACTAGT
AGGCAAAATGGTGCAAGAAGTAAAAGAAATCATATTGAATTATATTGAACATTATAAAAACCACCTAACTGATGTTATAC
ATATTGATGAAGACAAATTTGAAACACCTAAATTGTTTCAAACGGTTATTCAAATAAATACTTATACAGAAATGAAATTA
GTTTTCTTAGAAGGAATCTTTAAAACCTTATTGAATAAGAACAGTCAAGTTGTCTTTTTCATCATGCCATCGATTTTAAA
AAGTAAAAATACCATGTCCGAAGAAGAAAAATTCGCAATCATTAAAACAATAATTGAAAGTGATTTAAAGATAGCATTTA
ATATAAATGATATTGAAACAACTTATTATGTTGAAGAAGCTTTTATGAGTGTTTTTAGACAAATATCTCCAAACGAATTA
AGTAATCATAATAATTACGAAGTGCATTTTGTTTTTGATTTATCATTGATGGAAATTAGAACAATTTATCGAATGATATT
AAAATTACATAACATCATGTTGAATGTGAAATTAGGATTGAACATTACCTGTTTATTTGAAAAACCTTCAGTTTTTAAAT
CACTAGTATCACAAATAAAGCGACTTAAATTCGATTCGTTAATAATAGATAATGCAAATTTAAGTAGCCCTTATTTGATG
GGGGGAAGTGATGAGTTACTATTGAAAAATATTTTGCATTTTAAAAATTTAAAACAAGTAATTAATGAATTGGATATTGA
ACAAGAAAAGCTGATTTTTCTAAATGTTGAAAATCATAAACTGCTTAATAATAAAGAACAAGATTTAAGTAACAGTGCTC
CATTAATTTATAAGACATTAAGTGCGCTGTATCACAACTTTGCTGGGTTTGGATTGAACATTTTTGACAATCATAAAGCA
TTTAATGCGATGCATCTATATGACAAAAATGGATTTAAAACAACACTAGGTCTTATATTGGAAAAATTTATCGAATATGT
CTCGAAACCAAAATATGAAAACAGTTATTATTCTATTTTTGATATAGAGAATTATTATTGTCTTGTTATTTATGATTGGC
GAGTGATAGAGAGCGAGACAATTATGAGTAATTTTGAGGATAGTCAAGTTTATATAAATTTTAAAAACAATGTTTTAAAC
GATAAATATCTAATTGTAATAGAAACATTGGACGAAAATAGTGGCAACATTAATCATTTGATTTCTAAAGAATTAAGAGA
TAAATATGAATGGAACCCTAGTTTACTATCTAAAATTGACAACTACCTTAAACCAGCAATCGAGATTAAAGAGCATAATT
TTAGTGATAATTCCTTGAATATTAACGTTACTTTTAATGCGTTATACATAATTAAAATAGGAAAAAAATAA

Upstream 100 bases:

>100_bases
ATTTGGCATTCGTATTGTGTTAAATTTACGTTTAATTAAATAAGTTAAATATTATAGGGAATGATAAAAGTGGTACTTAA
ATATAGAAAGAGGTAAAGTT

Downstream 100 bases:

>100_bases
CACCTTGATATGTATTGCAAAATTTAATTTGCATTTGTTGGTAATTTTGACAACGTATTAAAAACAAATGAGAAAGACAA
TGGCAGAAAAATTTAAGATA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 716; Mature: 715

Protein sequence:

>716_residues
MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGF
TFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADVRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYI
YQNVNQRLTLKSVADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKS
YMDITPNEYRNLSKYNKCLMLKPESLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKFETPKLFQTVIQINTYTEMKL
VFLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFAIIKTIIESDLKIAFNINDIETTYYVEEAFMSVFRQISPNEL
SNHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLM
GGSDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKEQDLSNSAPLIYKTLSALYHNFAGFGLNIFDNHKA
FNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLN
DKYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK

Sequences:

>Translated_716_residues
MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGF
TFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADVRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYI
YQNVNQRLTLKSVADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKS
YMDITPNEYRNLSKYNKCLMLKPESLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKFETPKLFQTVIQINTYTEMKL
VFLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFAIIKTIIESDLKIAFNINDIETTYYVEEAFMSVFRQISPNEL
SNHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLM
GGSDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKEQDLSNSAPLIYKTLSALYHNFAGFGLNIFDNHKA
FNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLN
DKYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK
>Mature_715_residues
AKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGFT
FFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADVRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYIY
QNVNQRLTLKSVADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKSY
MDITPNEYRNLSKYNKCLMLKPESLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKFETPKLFQTVIQINTYTEMKLV
FLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFAIIKTIIESDLKIAFNINDIETTYYVEEAFMSVFRQISPNELS
NHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLMG
GSDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKEQDLSNSAPLIYKTLSALYHNFAGFGLNIFDNHKAF
NAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLND
KYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK

Specific function: Transcription Activator For The Expression Of The Melab Operon. Melr Binds At Two Sites Located Upstream Of The Melab Transcription Site. [C]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HTH araC/xylS-type DNA-binding domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 83937; Mature: 83806

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIK
CCCCEEEEEECCCEEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEEEEEEEEEE
NNKKTIMLYLSSDWFAELGFTFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADV
CCCEEEEEEECCCHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCCHHHH
RKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYIYQNVNQRLTLKSVADKLFVS
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCEEEHHHHHHHHHHC
KSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKS
CCCCCHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHH
YMDITPNEYRNLSKYNKCLMLKPESLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKF
HHCCCCHHHHCHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC
ETPKLFQTVIQINTYTEMKLVFLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFAI
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHCCCCCCCHHHHHHH
IKTIIESDLKIAFNINDIETTYYVEEAFMSVFRQISPNELSNHNNYEVHFVFDLSLMEIR
HHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECHHHHHH
TIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLM
HHHHHHHHHHHEEEEEEECCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEE
GGSDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKEQDLSNSAPLIYKTL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHCCCCCCCHHHHHH
SALYHNFAGFGLNIFDNHKAFNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIF
HHHHHHHCCCCCEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEE
DIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLNDKYLIVIETLDENSGNINHL
EECCEEEEEEEEEEEECCHHHHCCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCHHHH
ISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK
HHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEEEEEEEEEECCC
>Mature Secondary Structure 
AKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIK
CCCEEEEEECCCEEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEEEEEEEEEE
NNKKTIMLYLSSDWFAELGFTFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADV
CCCEEEEEEECCCHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCCHHHH
RKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYIYQNVNQRLTLKSVADKLFVS
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCEEEHHHHHHHHHHC
KSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKS
CCCCCHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHH
YMDITPNEYRNLSKYNKCLMLKPESLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKF
HHCCCCHHHHCHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC
ETPKLFQTVIQINTYTEMKLVFLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFAI
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHCCCCCCCHHHHHHH
IKTIIESDLKIAFNINDIETTYYVEEAFMSVFRQISPNELSNHNNYEVHFVFDLSLMEIR
HHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECHHHHHH
TIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLM
HHHHHHHHHHHEEEEEEECCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEE
GGSDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKEQDLSNSAPLIYKTL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHCCCCCCCHHHHHH
SALYHNFAGFGLNIFDNHKAFNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIF
HHHHHHHCCCCCEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEE
DIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLNDKYLIVIETLDENSGNINHL
EECCEEEEEEEEEEEECCHHHHCCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCHHHH
ISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK
HHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12044378 [H]