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The map label for this gene is ung

Identifier: 82750286

GI number: 82750286

Start: 596366

End: 597022

Strand: Direct

Name: ung

Synonym: SAB0531

Alternate gene names: 82750286

Gene position: 596366-597022 (Clockwise)

Preceding gene: 82750283

Following gene: 82750287

Centisome position: 21.75

GC content: 35.01

Gene sequence:

>657_bases
ATGGAATGGTCGCAAATTTTTCATGACATAACAACGAAACATGACTTTAAAGCTATGCATGATTTTTTAGAAAAAGAATA
TTCGACTGCAATCGTATACCCTGATAGGGAAAATATTTATCAAGCGTTTGATTTAACACCGTTTGAAAATATCAAAGTTG
TTATATTAGGACAAGACCCGTATCATGGTCCAAACCAAGCACATGGATTAGCATTTTCAGTGCAACCTAACGCAAAATTC
CCTCCATCTTTACGTAATATGTATAAAGAATTAGCAGATGATATTGGATGTGTTAGACAAACACCACATTTACAAGATTG
GGCAAGAGAAGGCGTCTTGTTATTGAATACAGTTTTAACCGTAAGACAGGGTGAAGCAAATTCTCATCGTGATATTGGTT
GGGAAACATTTACTGATGAAATTATTAAAGCAGTGTCTGATTATAAAGAACATGTTGTCTTTATTTTGTGGGGGAAACCT
GCACAGCAAAAAATAAAGCTTATCGATACATCTAAACATTGTATTATAAAATCAGTGCATCCTAGTCCACTGTCTGCATA
TAGAGGATTCTTTGGATCAAAACCGTATTCCAAAGCGAATACCTATTTAGAGTCAGTAGGAAAATCACCAATTAATTGGT
GTGAAAGTGAGGCGTAG

Upstream 100 bases:

>100_bases
TGATTGTTGAAATGAATCATTCATACTATTGTAACTTTTGAAAATGTCATTCACTTTAGATAAGTGTGATATGTTAAAAT
ATGTCCTGAGGTGAGATTGA

Downstream 100 bases:

>100_bases
ATGGTGAATAGAGAAACTTTAATAGCACGAATTGAGCAAGAATTAGTACAAGCAGAGCAGGCGCAGCATGACCATGACTT
TGAAAAACATATGTATGCCA

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MEWSQIFHDITTKHDFKAMHDFLEKEYSTAIVYPDRENIYQAFDLTPFENIKVVILGQDPYHGPNQAHGLAFSVQPNAKF
PPSLRNMYKELADDIGCVRQTPHLQDWAREGVLLLNTVLTVRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKP
AQQKIKLIDTSKHCIIKSVHPSPLSAYRGFFGSKPYSKANTYLESVGKSPINWCESEA

Sequences:

>Translated_218_residues
MEWSQIFHDITTKHDFKAMHDFLEKEYSTAIVYPDRENIYQAFDLTPFENIKVVILGQDPYHGPNQAHGLAFSVQPNAKF
PPSLRNMYKELADDIGCVRQTPHLQDWAREGVLLLNTVLTVRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKP
AQQKIKLIDTSKHCIIKSVHPSPLSAYRGFFGSKPYSKANTYLESVGKSPINWCESEA
>Mature_218_residues
MEWSQIFHDITTKHDFKAMHDFLEKEYSTAIVYPDRENIYQAFDLTPFENIKVVILGQDPYHGPNQAHGLAFSVQPNAKF
PPSLRNMYKELADDIGCVRQTPHLQDWAREGVLLLNTVLTVRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKP
AQQKIKLIDTSKHCIIKSVHPSPLSAYRGFFGSKPYSKANTYLESVGKSPINWCESEA

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=202, Percent_Identity=48.5148514851485, Blast_Score=198, Evalue=3e-51,
Organism=Homo sapiens, GI6224979, Length=202, Percent_Identity=48.5148514851485, Blast_Score=198, Evalue=3e-51,
Organism=Escherichia coli, GI1788934, Length=189, Percent_Identity=54.4973544973545, Blast_Score=222, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17556304, Length=217, Percent_Identity=49.7695852534562, Blast_Score=209, Evalue=8e-55,
Organism=Saccharomyces cerevisiae, GI6323620, Length=220, Percent_Identity=45, Blast_Score=170, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 24967; Mature: 24967

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWSQIFHDITTKHDFKAMHDFLEKEYSTAIVYPDRENIYQAFDLTPFENIKVVILGQDP
CCHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEECCHHHHHHHHCCCCCCCEEEEEECCCC
YHGPNQAHGLAFSVQPNAKFPPSLRNMYKELADDIGCVRQTPHLQDWAREGVLLLNTVLT
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHH
VRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKPAQQKIKLIDTSKHCIIKSVH
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHEEEEECCCCEEEEECC
PSPLSAYRGFFGSKPYSKANTYLESVGKSPINWCESEA
CCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure
MEWSQIFHDITTKHDFKAMHDFLEKEYSTAIVYPDRENIYQAFDLTPFENIKVVILGQDP
CCHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEECCHHHHHHHHCCCCCCCEEEEEECCCC
YHGPNQAHGLAFSVQPNAKFPPSLRNMYKELADDIGCVRQTPHLQDWAREGVLLLNTVLT
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHH
VRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKPAQQKIKLIDTSKHCIIKSVH
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHEEEEECCCCEEEEECC
PSPLSAYRGFFGSKPYSKANTYLESVGKSPINWCESEA
CCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA