Click here to switch to the map view.

The map label for this gene is hxlB [H]

Identifier: 82750276

GI number: 82750276

Start: 587570

End: 588118

Strand: Direct

Name: hxlB [H]

Synonym: SAB0521

Alternate gene names: 82750276

Gene position: 587570-588118 (Clockwise)

Preceding gene: 82750275

Following gene: 82750277

Centisome position: 21.42

GC content: 36.79

Gene sequence:

>549_bases
ATGGCTAAATTTAGTGACTATCAATTAATTCTAGATGAATTAAAGATGACTTTGTCACATGTTGAAGCGGATGAGTTTTC
AACGTTTGCGTCCAAAATACTACATGCTGAACATATATTTGTAGCTGGCAAAGGACGTTCAGGATTCGTGGCGAATAGCT
TTGCAATGCGCTTAAATCAGCTCGGCAAACAGGCACATGTTGTTGGAGAATCAACGACACCTGCGATTAAGTCGAATGAT
GTATTTGTAATTATCTCTGGTTCAGGTTCCACGGAACATTTAAGATTATTAGCAGACAAAGCAAAATCAGTAGGTGCTGA
CATCGTATTAATTACTACAAATAAAGATTCTGCAATAGGCAATCTAGCTGGGACGAACATCGTTTTGCCTGCAGGTACAA
AATATGATGAACAAGGTTCGGCACAACCATTAGGAAGTTTGTTTGAACAAGCATCACAATTATTTTTAGATAGTGTTGTA
ATGGGATTGATGACTGAAATGAATGTTTCAGAACAAACGATGCAACAAAATCATGCTAATTTAGAATAA

Upstream 100 bases:

>100_bases
GAAAGTCCTGATCTTGTTATTGTTGGTGGCGGAATCGCAAATGCAGATGATCCAGTAGAAGCTGCAAAACAATGTCGCGC
TGCAATCGAAGGTAAGTAAT

Downstream 100 bases:

>100_bases
AAACAAAGATAGTCGATAATATGATGCCTAGGCAGAAATATTATCGATTATTTTTTATTTAAATAATAAATTATAGTATA
ATATCAATAATAAACGAATA

Product: 6-phospho-3-hexuloisomerase

Products: NA

Alternate protein names: 6-phospho-3-hexuloisomerase; PHI [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MAKFSDYQLILDELKMTLSHVEADEFSTFASKILHAEHIFVAGKGRSGFVANSFAMRLNQLGKQAHVVGESTTPAIKSND
VFVIISGSGSTEHLRLLADKAKSVGADIVLITTNKDSAIGNLAGTNIVLPAGTKYDEQGSAQPLGSLFEQASQLFLDSVV
MGLMTEMNVSEQTMQQNHANLE

Sequences:

>Translated_182_residues
MAKFSDYQLILDELKMTLSHVEADEFSTFASKILHAEHIFVAGKGRSGFVANSFAMRLNQLGKQAHVVGESTTPAIKSND
VFVIISGSGSTEHLRLLADKAKSVGADIVLITTNKDSAIGNLAGTNIVLPAGTKYDEQGSAQPLGSLFEQASQLFLDSVV
MGLMTEMNVSEQTMQQNHANLE
>Mature_181_residues
AKFSDYQLILDELKMTLSHVEADEFSTFASKILHAEHIFVAGKGRSGFVANSFAMRLNQLGKQAHVVGESTTPAIKSNDV
FVIISGSGSTEHLRLLADKAKSVGADIVLITTNKDSAIGNLAGTNIVLPAGTKYDEQGSAQPLGSLFEQASQLFLDSVVM
GLMTEMNVSEQTMQQNHANLE

Specific function: Catalyzes the isomerization between 3-hexulose 6- phosphate and fructose 6-phosphate. Together with hxlA, may act as a formaldehyde detoxification system [H]

COG id: COG0794

COG function: function code M; Predicted sugar phosphate isomerase involved in capsule formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017552
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.27 [H]

Molecular weight: Translated: 19544; Mature: 19413

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFSDYQLILDELKMTLSHVEADEFSTFASKILHAEHIFVAGKGRSGFVANSFAMRLNQ
CCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHH
LGKQAHVVGESTTPAIKSNDVFVIISGSGSTEHLRLLADKAKSVGADIVLITTNKDSAIG
HCCHHEEECCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
NLAGTNIVLPAGTKYDEQGSAQPLGSLFEQASQLFLDSVVMGLMTEMNVSEQTMQQNHAN
CCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
LE
CC
>Mature Secondary Structure 
AKFSDYQLILDELKMTLSHVEADEFSTFASKILHAEHIFVAGKGRSGFVANSFAMRLNQ
CCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHH
LGKQAHVVGESTTPAIKSNDVFVIISGSGSTEHLRLLADKAKSVGADIVLITTNKDSAIG
HCCHHEEECCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
NLAGTNIVLPAGTKYDEQGSAQPLGSLFEQASQLFLDSVVMGLMTEMNVSEQTMQQNHAN
CCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
LE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 7921238 [H]