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The map label for this gene is ilvE [H]

Identifier: 82750262

GI number: 82750262

Start: 567791

End: 568867

Strand: Direct

Name: ilvE [H]

Synonym: SAB0505

Alternate gene names: 82750262

Gene position: 567791-568867 (Clockwise)

Preceding gene: 82750261

Following gene: 82750263

Centisome position: 20.7

GC content: 35.0

Gene sequence:

>1077_bases
ATGTCACAAGCAGTTAAAGTTGAACGACGAGAAACATTAAAACAAAAACCAAATACATCTCAACTAGGTTTTGGTAAATA
TTTTACTGATTATATGTTGAGTTATGATTATGATGCAGATAAAGGATGGCATGATTTGAAGATAGTACCTTATGGTCCTA
TTGAAATTTCACCTGCTGCACAAGGTGTTCATTATGGTCAATCGGTATTCGAAGGATTAAAAGCATATAAAAGAGATGGG
AAAGTTGCACTTTTCCGTCCTGAAGAAAATTTTAAGCGTCTTAATAACTCGTTAGCACGATTAGAAATGCCTCAAGTAGA
CGAAGCAGAATTGTTAGAGGGGCTAAAACAATTAGTTGATATAGAGAGAGATTGGATTCCTGAAGGGGAAGGTCAATCAT
TATATATTCGTCCATTTGTTTTTGCAACAGAAGGGGCACTTGGTGTTGGTGCATCACATCAGTATAAATTATTAATTATT
TTATCTCCTTCAGGTGCATATTATGGTGGTGAAACCTTAAAACCAACTAAAATCTATGTAGAAGATGAATATGTGCGTGC
TGTTCGTGGCGGTGTAGGCTTTGCGAAAGTTGCAGGTAACTATGCAGCAAGTTTATTAGCACAAACTAATGCAAATAAAT
TAGGTTATGACCAAGTATTATGGCTTGATGGTGTTGAACAGAAATATATCGAAGAAGTTGGTAGCATGAACATTTTCTTC
GTTGAAAATGGCAAAGTAATTACACCAGAGTTGAATGGCAGTATTTTACCTGGTATTACACGTAAATCTATCATCGAATT
AGCTAAAAACTTAGGATATGAAGTCGAAGAGCGTCGCGTTTCAATCGATGAATTATTCGAATCATATGATAAAGGTGAGT
TAACAGAAGTATTTGGTAGTGGTACTGCAGCAGTTATTTCACCTGTGGGTACATTGAGATACGAAGATCGTGAAATCGTT
ATTAATAATAATGAGACTGGTGAAATTACTCAAAAATTATACGACGTCTATACTGGTATTCAAAATGGTACTTTAGAAGA
TAAAAATGGTTGGAGAGTCGTTGTACCAAAATATTAA

Upstream 100 bases:

>100_bases
TTAATTTTGAATTTTTAGAAAATTATTGAACAGCATAATATGGATTGTTATAATTTAAGTTAAACAAATTCTTATACAAT
ATTATTAGGAGGCAATCACC

Downstream 100 bases:

>100_bases
TAAAAATTGAATATGATCATGAAAACAATATGTAAAAGTTAATCATGACTAAAATCCTTTTCAATGAAGCGAAGCATGGT
AATAAATTAAGTTTACAATG

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSQAVKVERRETLKQKPNTSQLGFGKYFTDYMLSYDYDADKGWHDLKIVPYGPIEISPAAQGVHYGQSVFEGLKAYKRDG
KVALFRPEENFKRLNNSLARLEMPQVDEAELLEGLKQLVDIERDWIPEGEGQSLYIRPFVFATEGALGVGASHQYKLLII
LSPSGAYYGGETLKPTKIYVEDEYVRAVRGGVGFAKVAGNYAASLLAQTNANKLGYDQVLWLDGVEQKYIEEVGSMNIFF
VENGKVITPELNGSILPGITRKSIIELAKNLGYEVEERRVSIDELFESYDKGELTEVFGSGTAAVISPVGTLRYEDREIV
INNNETGEITQKLYDVYTGIQNGTLEDKNGWRVVVPKY

Sequences:

>Translated_358_residues
MSQAVKVERRETLKQKPNTSQLGFGKYFTDYMLSYDYDADKGWHDLKIVPYGPIEISPAAQGVHYGQSVFEGLKAYKRDG
KVALFRPEENFKRLNNSLARLEMPQVDEAELLEGLKQLVDIERDWIPEGEGQSLYIRPFVFATEGALGVGASHQYKLLII
LSPSGAYYGGETLKPTKIYVEDEYVRAVRGGVGFAKVAGNYAASLLAQTNANKLGYDQVLWLDGVEQKYIEEVGSMNIFF
VENGKVITPELNGSILPGITRKSIIELAKNLGYEVEERRVSIDELFESYDKGELTEVFGSGTAAVISPVGTLRYEDREIV
INNNETGEITQKLYDVYTGIQNGTLEDKNGWRVVVPKY
>Mature_357_residues
SQAVKVERRETLKQKPNTSQLGFGKYFTDYMLSYDYDADKGWHDLKIVPYGPIEISPAAQGVHYGQSVFEGLKAYKRDGK
VALFRPEENFKRLNNSLARLEMPQVDEAELLEGLKQLVDIERDWIPEGEGQSLYIRPFVFATEGALGVGASHQYKLLIIL
SPSGAYYGGETLKPTKIYVEDEYVRAVRGGVGFAKVAGNYAASLLAQTNANKLGYDQVLWLDGVEQKYIEEVGSMNIFFV
ENGKVITPELNGSILPGITRKSIIELAKNLGYEVEERRVSIDELFESYDKGELTEVFGSGTAAVISPVGTLRYEDREIVI
NNNETGEITQKLYDVYTGIQNGTLEDKNGWRVVVPKY

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI50658084, Length=331, Percent_Identity=39.8791540785499, Blast_Score=260, Evalue=1e-69,
Organism=Homo sapiens, GI296010904, Length=351, Percent_Identity=39.031339031339, Blast_Score=257, Evalue=1e-68,
Organism=Homo sapiens, GI38176287, Length=351, Percent_Identity=39.031339031339, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI296010906, Length=351, Percent_Identity=39.031339031339, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI258614015, Length=266, Percent_Identity=41.3533834586466, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI296010902, Length=350, Percent_Identity=35.1428571428571, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI296010900, Length=350, Percent_Identity=35.1428571428571, Blast_Score=213, Evalue=2e-55,
Organism=Escherichia coli, GI48994963, Length=316, Percent_Identity=33.2278481012658, Blast_Score=155, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17568601, Length=356, Percent_Identity=39.0449438202247, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17565728, Length=358, Percent_Identity=36.8715083798883, Blast_Score=217, Evalue=7e-57,
Organism=Saccharomyces cerevisiae, GI6322608, Length=356, Percent_Identity=39.8876404494382, Blast_Score=240, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6322002, Length=356, Percent_Identity=38.2022471910112, Blast_Score=233, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24641779, Length=362, Percent_Identity=37.5690607734807, Blast_Score=234, Evalue=8e-62,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005786 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 40086; Mature: 39955

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQAVKVERRETLKQKPNTSQLGFGKYFTDYMLSYDYDADKGWHDLKIVPYGPIEISPAA
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHEEECCCCCCCCCEEEEEECCCEEECCCC
QGVHYGQSVFEGLKAYKRDGKVALFRPEENFKRLNNSLARLEMPQVDEAELLEGLKQLVD
CCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
IERDWIPEGEGQSLYIRPFVFATEGALGVGASHQYKLLIILSPSGAYYGGETLKPTKIYV
HHHHCCCCCCCCEEEEEEEEEEECCCEECCCCCCEEEEEEECCCCCCCCCCCCCCCEEEE
EDEYVRAVRGGVGFAKVAGNYAASLLAQTNANKLGYDQVLWLDGVEQKYIEEVGSMNIFF
EHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCEEEEE
VENGKVITPELNGSILPGITRKSIIELAKNLGYEVEERRVSIDELFESYDKGELTEVFGS
EECCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCHHHHHHHCCCCCHHHHHCC
GTAAVISPVGTLRYEDREIVINNNETGEITQKLYDVYTGIQNGTLEDKNGWRVVVPKY
CCEEEECCCHHEEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCC
>Mature Secondary Structure 
SQAVKVERRETLKQKPNTSQLGFGKYFTDYMLSYDYDADKGWHDLKIVPYGPIEISPAA
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHEEECCCCCCCCCEEEEEECCCEEECCCC
QGVHYGQSVFEGLKAYKRDGKVALFRPEENFKRLNNSLARLEMPQVDEAELLEGLKQLVD
CCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
IERDWIPEGEGQSLYIRPFVFATEGALGVGASHQYKLLIILSPSGAYYGGETLKPTKIYV
HHHHCCCCCCCCEEEEEEEEEEECCCEECCCCCCEEEEEEECCCCCCCCCCCCCCCEEEE
EDEYVRAVRGGVGFAKVAGNYAASLLAQTNANKLGYDQVLWLDGVEQKYIEEVGSMNIFF
EHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCEEEEE
VENGKVITPELNGSILPGITRKSIIELAKNLGYEVEERRVSIDELFESYDKGELTEVFGS
EECCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCHHHHHHHCCCCCHHHHHCC
GTAAVISPVGTLRYEDREIVINNNETGEITQKLYDVYTGIQNGTLEDKNGWRVVVPKY
CCEEEECCCHHEEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA