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The map label for this gene is degT [H]

Identifier: 82703322

GI number: 82703322

Start: 2503645

End: 2504769

Strand: Direct

Name: degT [H]

Synonym: Nmul_A2204

Alternate gene names: 82703322

Gene position: 2503645-2504769 (Clockwise)

Preceding gene: 82703321

Following gene: 82703323

Centisome position: 78.63

GC content: 58.04

Gene sequence:

>1125_bases
GTGATCGTCCCGCAACTCGATCTCGCGCAGGAGTATCAGCAGCTGCGTGCGGAAATCGACGCTGCTGTGCAGCGGGTGTT
TTTGAAAGGCGCATTTATCGACAGCGCAGAAAACGCGGTACTGGAACACGAGCTTGCGGAATACATCGGCGCTGCTGAAG
TCATCTGCGTCAATTCTGGCACCGACGCGCTGCTGCTCTCCCTCAAGGCATTGGGAATAGGAGCGGGCGATGACGTAATC
GTGCCCGCCTTCACCTTCTTTGCAACGGCAGAGGCGGTAAGCCTCGCGGGAGCGCGCCCCTGTTTTGCCGACTGTGCACC
CGGCCAATACAATATTGATGCGAGCAGCGTGGGGCAGGCGTTGACGCCGCGGACAAGAGCCGTCATCGCCGTCCATCTTT
TCGGGCAGCCGGTCGATTTAAAGCCGTTACAGGAATTCTGCGCAAGCCACAACTTGTGGTTGATCGAGGATGCGGCCCAA
GCAATCGGCGCGCGCTATCACGACCAGGGTATCGGATCCTTCGGTATCACCGGCGCCTTCAGCTTCTACCCCACAAAAAA
CCTAGGCACTTATGGCGACGGTGGAGCGATTGCCTGTAGCGATCCCGAGCTTGCGTCGCGATTGCGACGCCTTCGAAATC
ACGGACGGCAGGACCGCTACCAGCACACGGAAATCGGCTTCAACAGCCGTCTCGACGAACTCCAGGCAGCAATATTGAAG
GTCAAGCTTGCCTATCTGGATGACTGGAATGCGCAACGCCGCCAGCTCGCCACGCTCTACCAGCAAGCTCTGCAAAATAC
GGAATGCAACTGGCCGACAGTCCCTGAAGGCATTGTTCCCGTCCACCATCAGTTCGTAATTACCCATCCGCAGCGCGACG
CGCTGCAACTGTTTCTGGCAGAACACAATATTTCAACTGCCGTTTTCTATCCCATTCCCTGCCATCTGCAGCCGGCCTTC
TCGGAATCGCACGCCGGTGTCTCGCTGCCGCTGGCCGAACGTCTTGCCGATCAAGTGCTGGCCCTGCCTATCTACCCCGC
CCTGCCTCCCGAAGCGGTAAGGCATATCGGGGAACTGATACAGGATTTTGAACACGTCGAACACGGGAAGGGGAAATCAC
CCTGA

Upstream 100 bases:

>100_bases
CCTGCCGCAACCGTTCACTACCCCGGGTTACGCCGGCGGAAGGCAATGCTGCCCTGGAGCTGGCGCACTGCATCCGGCAG
CAGATACTCAGGCCCTGCCC

Downstream 100 bases:

>100_bases
CCTCCATTATTGATAGGGAACAAACCTTATGGCCACACTTCAGGAAAATGTCAGCATGGCGGTATTTTGTGACTTCGAAA
ATGTCGCTCTTGGCGTGCGT

Product: DegT/DnrJ/EryC1/StrS aminotransferase

Products: TDP-D-fucosamine; 2-oxoglutarate [C]

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MIVPQLDLAQEYQQLRAEIDAAVQRVFLKGAFIDSAENAVLEHELAEYIGAAEVICVNSGTDALLLSLKALGIGAGDDVI
VPAFTFFATAEAVSLAGARPCFADCAPGQYNIDASSVGQALTPRTRAVIAVHLFGQPVDLKPLQEFCASHNLWLIEDAAQ
AIGARYHDQGIGSFGITGAFSFYPTKNLGTYGDGGAIACSDPELASRLRRLRNHGRQDRYQHTEIGFNSRLDELQAAILK
VKLAYLDDWNAQRRQLATLYQQALQNTECNWPTVPEGIVPVHHQFVITHPQRDALQLFLAEHNISTAVFYPIPCHLQPAF
SESHAGVSLPLAERLADQVLALPIYPALPPEAVRHIGELIQDFEHVEHGKGKSP

Sequences:

>Translated_374_residues
MIVPQLDLAQEYQQLRAEIDAAVQRVFLKGAFIDSAENAVLEHELAEYIGAAEVICVNSGTDALLLSLKALGIGAGDDVI
VPAFTFFATAEAVSLAGARPCFADCAPGQYNIDASSVGQALTPRTRAVIAVHLFGQPVDLKPLQEFCASHNLWLIEDAAQ
AIGARYHDQGIGSFGITGAFSFYPTKNLGTYGDGGAIACSDPELASRLRRLRNHGRQDRYQHTEIGFNSRLDELQAAILK
VKLAYLDDWNAQRRQLATLYQQALQNTECNWPTVPEGIVPVHHQFVITHPQRDALQLFLAEHNISTAVFYPIPCHLQPAF
SESHAGVSLPLAERLADQVLALPIYPALPPEAVRHIGELIQDFEHVEHGKGKSP
>Mature_374_residues
MIVPQLDLAQEYQQLRAEIDAAVQRVFLKGAFIDSAENAVLEHELAEYIGAAEVICVNSGTDALLLSLKALGIGAGDDVI
VPAFTFFATAEAVSLAGARPCFADCAPGQYNIDASSVGQALTPRTRAVIAVHLFGQPVDLKPLQEFCASHNLWLIEDAAQ
AIGARYHDQGIGSFGITGAFSFYPTKNLGTYGDGGAIACSDPELASRLRRLRNHGRQDRYQHTEIGFNSRLDELQAAILK
VKLAYLDDWNAQRRQLATLYQQALQNTECNWPTVPEGIVPVHHQFVITHPQRDALQLFLAEHNISTAVFYPIPCHLQPAF
SESHAGVSLPLAERLADQVLALPIYPALPPEAVRHIGELIQDFEHVEHGKGKSP

Specific function: This membrane protein may function as a sensor protein and may transfer the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of the genes [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI2367285, Length=331, Percent_Identity=33.8368580060423, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI145693159, Length=364, Percent_Identity=32.1428571428571, Blast_Score=155, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 40814; Mature: 40814

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVPQLDLAQEYQQLRAEIDAAVQRVFLKGAFIDSAENAVLEHELAEYIGAAEVICVNSG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECC
TDALLLSLKALGIGAGDDVIVPAFTFFATAEAVSLAGARPCFADCAPGQYNIDASSVGQA
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCC
LTPRTRAVIAVHLFGQPVDLKPLQEFCASHNLWLIEDAAQAIGARYHDQGIGSFGITGAF
CCCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEHHHHHHHCCHHHHCCCCCCCCCCEE
SFYPTKNLGTYGDGGAIACSDPELASRLRRLRNHGRQDRYQHTEIGFNSRLDELQAAILK
EECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHH
VKLAYLDDWNAQRRQLATLYQQALQNTECNWPTVPEGIVPVHHQFVITHPQRDALQLFLA
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHH
EHNISTAVFYPIPCHLQPAFSESHAGVSLPLAERLADQVLALPIYPALPPEAVRHIGELI
HCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
QDFEHVEHGKGKSP
HHHHHHHCCCCCCC
>Mature Secondary Structure
MIVPQLDLAQEYQQLRAEIDAAVQRVFLKGAFIDSAENAVLEHELAEYIGAAEVICVNSG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECC
TDALLLSLKALGIGAGDDVIVPAFTFFATAEAVSLAGARPCFADCAPGQYNIDASSVGQA
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCC
LTPRTRAVIAVHLFGQPVDLKPLQEFCASHNLWLIEDAAQAIGARYHDQGIGSFGITGAF
CCCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEHHHHHHHCCHHHHCCCCCCCCCCEE
SFYPTKNLGTYGDGGAIACSDPELASRLRRLRNHGRQDRYQHTEIGFNSRLDELQAAILK
EECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHH
VKLAYLDDWNAQRRQLATLYQQALQNTECNWPTVPEGIVPVHHQFVITHPQRDALQLFLA
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHH
EHNISTAVFYPIPCHLQPAFSESHAGVSLPLAERLADQVLALPIYPALPPEAVRHIGELI
HCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
QDFEHVEHGKGKSP
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDP-4-dehydro-6-deoxy-D-glucose; L-glutamate [C]

Specific reaction: dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate = TDP-D-fucosamine + 2-oxoglutarate [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2104607 [H]