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The map label for this gene is serC [H]

Identifier: 82703308

GI number: 82703308

Start: 2487985

End: 2489073

Strand: Direct

Name: serC [H]

Synonym: Nmul_A2190

Alternate gene names: 82703308

Gene position: 2487985-2489073 (Clockwise)

Preceding gene: 82703307

Following gene: 82703309

Centisome position: 78.13

GC content: 53.63

Gene sequence:

>1089_bases
ATGGAACCCATCTATAACTTCAGCGCAGGTCCGGCGGTATTACCAAAGGAAGTTTTGCAGCAGGCGCGTGACGAAATGCT
TGATTGGCACGGCAGCGGTATGTCGGTGATGGAAATGAGTCACCGCGGCAAGGAATTCATGTCCATTGCGGCCAGGCTCG
AGACGGATTTGCGGGAATTGGCGAGCATCCCGCCCAACTACAAGGTACTCTTTTTGTCCGGCGGCGCTTCCAGCCAGTTC
GCGATGGTGCCGATGAACCTGGTGCGCGGAAAGAAAAGCGCCAACTATATCAATACTGGCCAGTGGTCCACGAAAGCGCT
CAAGGAAGCGAAAAAATATTGCGCCGTTCATGTTGCAGCTTCCTCGGAAGATGCAAATTTTACGTATGCTCCCACCCAGG
ATAAATGGAACATCGATCCGGAGGGAGCTTATCTGCACTACACGCCCAATGAGACGATTGGCGGAGTGGAGTTCAACTGG
ATTCCGGACTTGTCGGGTACCGATATACCCCTGGTGGCGGACATTTCTTCCGCCTTTATGTCACGCCCCCTGGATGTAAG
CCGGTTTGGGCTGATTTATGCCGGCACTCAGAAAAACGTGGGTCCCGCAGGCCTCTGTATCGTCATCGTGCGCGAGGACC
TGATAGGAACAACCGTGCCGGGCACACCGACCATGTTCGATTACAAGATTCACGCCGACAACGACTCCATGTACAACACG
CCGCCGACTTATGCGATGTATATCACGGGGCTGGTGGTGGAATGGCTGAAACAGAAAGGCGGGCTTCAGGCAATGGAGAA
AATCAACATTGCCAAGGCGCGTCTGCTGTACGACTTTCTGGACACTACTGATTTTTATCATTGCCCCGTGGCGAAACCCG
ACCGGTCGCGCATGAATGTGCCGTTCACTTTAAAAGATCCGGGGCTCGATGAAGAGTTTCTGAAACAGGCCCGAACGCAC
GGCCTCATCCAGTTGAAAGGCCATCGTTCTGTCGGCGGCATGCGCGCTTCGATATACAATGCGATGCCGCTTGAAGGCGT
AAAGGTCTTGGTGGAATTCATGAAGGAATTTGCGAGCAATCATGCCTGA

Upstream 100 bases:

>100_bases
GTGGAAACTGACGAAGCGCCAGGATTAGGGGAAGGCTTAGCCACGGATTTGCCGTGAACAGCCAGAGTAAGAACTCATGA
GGAATTCATAAGGAACTCCG

Downstream 100 bases:

>100_bases
ACGTGCACATAAAATCTTCCGGATACTGACCCTCAACCAGATTTCGCCGCTGGGCCTCAAGCTTTTCAGTTCCAGCCATT
ATAAAGTGGGCAGCGACACA

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MEPIYNFSAGPAVLPKEVLQQARDEMLDWHGSGMSVMEMSHRGKEFMSIAARLETDLRELASIPPNYKVLFLSGGASSQF
AMVPMNLVRGKKSANYINTGQWSTKALKEAKKYCAVHVAASSEDANFTYAPTQDKWNIDPEGAYLHYTPNETIGGVEFNW
IPDLSGTDIPLVADISSAFMSRPLDVSRFGLIYAGTQKNVGPAGLCIVIVREDLIGTTVPGTPTMFDYKIHADNDSMYNT
PPTYAMYITGLVVEWLKQKGGLQAMEKINIAKARLLYDFLDTTDFYHCPVAKPDRSRMNVPFTLKDPGLDEEFLKQARTH
GLIQLKGHRSVGGMRASIYNAMPLEGVKVLVEFMKEFASNHA

Sequences:

>Translated_362_residues
MEPIYNFSAGPAVLPKEVLQQARDEMLDWHGSGMSVMEMSHRGKEFMSIAARLETDLRELASIPPNYKVLFLSGGASSQF
AMVPMNLVRGKKSANYINTGQWSTKALKEAKKYCAVHVAASSEDANFTYAPTQDKWNIDPEGAYLHYTPNETIGGVEFNW
IPDLSGTDIPLVADISSAFMSRPLDVSRFGLIYAGTQKNVGPAGLCIVIVREDLIGTTVPGTPTMFDYKIHADNDSMYNT
PPTYAMYITGLVVEWLKQKGGLQAMEKINIAKARLLYDFLDTTDFYHCPVAKPDRSRMNVPFTLKDPGLDEEFLKQARTH
GLIQLKGHRSVGGMRASIYNAMPLEGVKVLVEFMKEFASNHA
>Mature_362_residues
MEPIYNFSAGPAVLPKEVLQQARDEMLDWHGSGMSVMEMSHRGKEFMSIAARLETDLRELASIPPNYKVLFLSGGASSQF
AMVPMNLVRGKKSANYINTGQWSTKALKEAKKYCAVHVAASSEDANFTYAPTQDKWNIDPEGAYLHYTPNETIGGVEFNW
IPDLSGTDIPLVADISSAFMSRPLDVSRFGLIYAGTQKNVGPAGLCIVIVREDLIGTTVPGTPTMFDYKIHADNDSMYNT
PPTYAMYITGLVVEWLKQKGGLQAMEKINIAKARLLYDFLDTTDFYHCPVAKPDRSRMNVPFTLKDPGLDEEFLKQARTH
GLIQLKGHRSVGGMRASIYNAMPLEGVKVLVEFMKEFASNHA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=365, Percent_Identity=46.027397260274, Blast_Score=358, Evalue=3e-99,
Organism=Homo sapiens, GI10863955, Length=360, Percent_Identity=40.8333333333333, Blast_Score=301, Evalue=5e-82,
Organism=Escherichia coli, GI1787136, Length=363, Percent_Identity=55.0964187327824, Blast_Score=416, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17506897, Length=361, Percent_Identity=46.814404432133, Blast_Score=333, Evalue=6e-92,
Organism=Saccharomyces cerevisiae, GI6324758, Length=386, Percent_Identity=39.8963730569948, Blast_Score=270, Evalue=2e-73,
Organism=Drosophila melanogaster, GI21356589, Length=363, Percent_Identity=47.3829201101928, Blast_Score=367, Evalue=1e-101,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40178; Mature: 40178

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPIYNFSAGPAVLPKEVLQQARDEMLDWHGSGMSVMEMSHRGKEFMSIAARLETDLREL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHH
ASIPPNYKVLFLSGGASSQFAMVPMNLVRGKKSANYINTGQWSTKALKEAKKYCAVHVAA
HCCCCCCEEEEEECCCCCCEEEECHHHHCCCCCCCCEECCCCHHHHHHHHHHHEEEEEEE
SSEDANFTYAPTQDKWNIDPEGAYLHYTPNETIGGVEFNWIPDLSGTDIPLVADISSAFM
CCCCCCEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCEEEEHHHHHHH
SRPLDVSRFGLIYAGTQKNVGPAGLCIVIVREDLIGTTVPGTPTMFDYKIHADNDSMYNT
CCCCCHHHCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCC
PPTYAMYITGLVVEWLKQKGGLQAMEKINIAKARLLYDFLDTTDFYHCPVAKPDRSRMNV
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCC
PFTLKDPGLDEEFLKQARTHGLIQLKGHRSVGGMRASIYNAMPLEGVKVLVEFMKEFASN
CEEECCCCCCHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCC
HA
CC
>Mature Secondary Structure
MEPIYNFSAGPAVLPKEVLQQARDEMLDWHGSGMSVMEMSHRGKEFMSIAARLETDLREL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHH
ASIPPNYKVLFLSGGASSQFAMVPMNLVRGKKSANYINTGQWSTKALKEAKKYCAVHVAA
HCCCCCCEEEEEECCCCCCEEEECHHHHCCCCCCCCEECCCCHHHHHHHHHHHEEEEEEE
SSEDANFTYAPTQDKWNIDPEGAYLHYTPNETIGGVEFNWIPDLSGTDIPLVADISSAFM
CCCCCCEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCEEEEHHHHHHH
SRPLDVSRFGLIYAGTQKNVGPAGLCIVIVREDLIGTTVPGTPTMFDYKIHADNDSMYNT
CCCCCHHHCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCC
PPTYAMYITGLVVEWLKQKGGLQAMEKINIAKARLLYDFLDTTDFYHCPVAKPDRSRMNV
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCC
PFTLKDPGLDEEFLKQARTHGLIQLKGHRSVGGMRASIYNAMPLEGVKVLVEFMKEFASN
CEEECCCCCCHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCC
HA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA