Click here to switch to the map view.

The map label for this gene is ubiG

Identifier: 82703304

GI number: 82703304

Start: 2482233

End: 2482952

Strand: Reverse

Name: ubiG

Synonym: Nmul_A2186

Alternate gene names: 82703304

Gene position: 2482952-2482233 (Counterclockwise)

Preceding gene: 82703305

Following gene: 82703303

Centisome position: 77.98

GC content: 56.25

Gene sequence:

>720_bases
ATGATGGATAAAGAAATCGAAAATGGCAGTGTCAACGTTGATCTGCTGGAACTGGAAAAATTCAACCAGCTCGCGCATCG
CTGGTGGGATCCCAACAGTGAATTCAAGCCGCTGCATGAGATCAATCCGCTGCGGCTGGGTTACATAGACCGCCACGCCC
GCCTGGCGGGTAAAGACGTCCTGGATGTCGGCTGTGGCGGAGGTATCCTGTCTGAAAGCATGGCTGAGAGCGGCGCGCAG
GTAACCGGCATCGATCTGGGCGACAAGGCGCTGAAGGTGGCAAAGCTGCACCTGCTGGAAAGCGGGAATAAAGTCAATTA
CCGCAAGAGCTCAGTGGAAGCGCTCGCGGCGGAGCAGCCCCATCATTACGATGTGGTCACCTGCATGGAAATGCTGGAGC
ACGTGCCGGATCCAGTCAGCACGGTGAGAGCTTGCGCGGAGCTCGCCAAGCCCGGTGGCTGGGTATTCTTCTCGACCATC
AATCGCAACCCCAAATCGTACCTGTTTGCCGTGATCGGGGCGGAATACGTGTTGAACCTGCTGCCGCGCGGGACGCACGA
CTATGCCAAATTCATCAAACCGTCTGAACTTGGACGCATGGCGCGCGAAGCAGGGTTGGATGTGCAGGAAGTAATCGGCA
TGAGCTACAATCCCATCACCAAAGTTTACTCCCTGGGACAGGATACCGATGTGAACTACATCATGGCATTCCGTGCCTGA

Upstream 100 bases:

>100_bases
GTGACTCGGAATTGACTACGCTGGACCGGGAAGAATTGGTGCACAGGGCTGAATTCTGGCGGGAACAAATGACAACGGGC
GTGATAGCAGTTCACGAAAA

Downstream 100 bases:

>100_bases
AACCCCTCGCGCTCCAAGGCCAGACTCCAAGCGATCATTTCAGTTGAGCCCGGTCATCGGTGACATCATCAATCTGGATT
GGCGCCCATCTTTATTCCTC

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MMDKEIENGSVNVDLLELEKFNQLAHRWWDPNSEFKPLHEINPLRLGYIDRHARLAGKDVLDVGCGGGILSESMAESGAQ
VTGIDLGDKALKVAKLHLLESGNKVNYRKSSVEALAAEQPHHYDVVTCMEMLEHVPDPVSTVRACAELAKPGGWVFFSTI
NRNPKSYLFAVIGAEYVLNLLPRGTHDYAKFIKPSELGRMAREAGLDVQEVIGMSYNPITKVYSLGQDTDVNYIMAFRA

Sequences:

>Translated_239_residues
MMDKEIENGSVNVDLLELEKFNQLAHRWWDPNSEFKPLHEINPLRLGYIDRHARLAGKDVLDVGCGGGILSESMAESGAQ
VTGIDLGDKALKVAKLHLLESGNKVNYRKSSVEALAAEQPHHYDVVTCMEMLEHVPDPVSTVRACAELAKPGGWVFFSTI
NRNPKSYLFAVIGAEYVLNLLPRGTHDYAKFIKPSELGRMAREAGLDVQEVIGMSYNPITKVYSLGQDTDVNYIMAFRA
>Mature_239_residues
MMDKEIENGSVNVDLLELEKFNQLAHRWWDPNSEFKPLHEINPLRLGYIDRHARLAGKDVLDVGCGGGILSESMAESGAQ
VTGIDLGDKALKVAKLHLLESGNKVNYRKSSVEALAAEQPHHYDVVTCMEMLEHVPDPVSTVRACAELAKPGGWVFFSTI
NRNPKSYLFAVIGAEYVLNLLPRGTHDYAKFIKPSELGRMAREAGLDVQEVIGMSYNPITKVYSLGQDTDVNYIMAFRA

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=239, Percent_Identity=35.5648535564854, Blast_Score=169, Evalue=2e-42,
Organism=Escherichia coli, GI1788564, Length=225, Percent_Identity=61.3333333333333, Blast_Score=283, Evalue=5e-78,
Organism=Caenorhabditis elegans, GI115533050, Length=241, Percent_Identity=35.6846473029046, Blast_Score=140, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6324476, Length=232, Percent_Identity=33.1896551724138, Blast_Score=116, Evalue=3e-27,
Organism=Drosophila melanogaster, GI281365311, Length=238, Percent_Identity=34.0336134453782, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24585589, Length=221, Percent_Identity=37.10407239819, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_NITMU (Q2Y6Z3)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_412870.1
- ProteinModelPortal:   Q2Y6Z3
- SMR:   Q2Y6Z3
- STRING:   Q2Y6Z3
- GeneID:   3785997
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A2186
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- PhylomeDB:   Q2Y6Z3
- ProtClustDB:   PRK05134
- BioCyc:   NMUL323848:NMUL_A2186-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 26547; Mature: 26547

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDKEIENGSVNVDLLELEKFNQLAHRWWDPNSEFKPLHEINPLRLGYIDRHARLAGKDV
CCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEECHHHHHHHHCCCCC
LDVGCGGGILSESMAESGAQVTGIDLGDKALKVAKLHLLESGNKVNYRKSSVEALAAEQP
EEECCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
HHYDVVTCMEMLEHVPDPVSTVRACAELAKPGGWVFFSTINRNPKSYLFAVIGAEYVLNL
CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
LPRGTHDYAKFIKPSELGRMAREAGLDVQEVIGMSYNPITKVYSLGQDTDVNYIMAFRA
CCCCCHHHHHHCCHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHCCCCCCCEEEEEECC
>Mature Secondary Structure
MMDKEIENGSVNVDLLELEKFNQLAHRWWDPNSEFKPLHEINPLRLGYIDRHARLAGKDV
CCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEECHHHHHHHHCCCCC
LDVGCGGGILSESMAESGAQVTGIDLGDKALKVAKLHLLESGNKVNYRKSSVEALAAEQP
EEECCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
HHYDVVTCMEMLEHVPDPVSTVRACAELAKPGGWVFFSTINRNPKSYLFAVIGAEYVLNL
CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
LPRGTHDYAKFIKPSELGRMAREAGLDVQEVIGMSYNPITKVYSLGQDTDVNYIMAFRA
CCCCCHHHHHHCCHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA