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The map label for this gene is ppa [H]

Identifier: 82703212

GI number: 82703212

Start: 2384635

End: 2385183

Strand: Direct

Name: ppa [H]

Synonym: Nmul_A2093

Alternate gene names: 82703212

Gene position: 2384635-2385183 (Clockwise)

Preceding gene: 82703207

Following gene: 82703213

Centisome position: 74.89

GC content: 51.37

Gene sequence:

>549_bases
ATGAATCTTGACAGAGTCAGCTCCGGCCGTGACGTGCCGAACGATTTCAATGTCATCATAGAAATACCCATGAACGCTGA
CCCCATCAAATACGAGGTGAATAAGGAAACGGGTGCAATGTTCGTTGATCGCTTCATGTCGACATGCATGCACTATCCCT
GTAACTACGGTTATATCCCGCACACCCTCTCGGAAGATGGAGATCCGGTGGATGTTCTGGTAATTTCACCGGTTCCACTC
ATCTCAGGAGTGGTGGTAAGGTGCCGGCCACTGGGTATGCTTCAAATGACCGATGAGGCGGGCGGAGATGCGAAGGTCCT
GGCGGTGCCAATCGACAAACTGTGCGCTCTCTATCGCGGGGTGAAATCTCACGCCGACTTGTCTGAACTGACACGCTCAC
AGATTGCCCATTTTTTTGAACACTACAAGGACCTGGAACCCGGCAAATGGGTGAAGATAACCGGATGGGCAGGGGTGACG
GAAGCCGAAGTGGAAATTACAAGCGGAGTGAATCGCTATAACGCGGCCGCGAAAAAACCAATGTTTTAA

Upstream 100 bases:

>100_bases
CAAGCTGAGCAGCATGCGCATGGATCGTTTAATCCGCAGTTAAACACCGAAGCCGACAGCTATAATAGCGATTTTTCAGT
GAACAGTAACAGGAACAAGA

Downstream 100 bases:

>100_bases
AAGCAATGTCAAGGTTTCAGAGCTTGGCAGAACACCGCCAAACAACGGGCAGCATGAAAAAATGAGTTGGCTCGAACGCA
TCGTATTGAAGGGCGAGGTT

Product: inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MNLDRVSSGRDVPNDFNVIIEIPMNADPIKYEVNKETGAMFVDRFMSTCMHYPCNYGYIPHTLSEDGDPVDVLVISPVPL
ISGVVVRCRPLGMLQMTDEAGGDAKVLAVPIDKLCALYRGVKSHADLSELTRSQIAHFFEHYKDLEPGKWVKITGWAGVT
EAEVEITSGVNRYNAAAKKPMF

Sequences:

>Translated_182_residues
MNLDRVSSGRDVPNDFNVIIEIPMNADPIKYEVNKETGAMFVDRFMSTCMHYPCNYGYIPHTLSEDGDPVDVLVISPVPL
ISGVVVRCRPLGMLQMTDEAGGDAKVLAVPIDKLCALYRGVKSHADLSELTRSQIAHFFEHYKDLEPGKWVKITGWAGVT
EAEVEITSGVNRYNAAAKKPMF
>Mature_182_residues
MNLDRVSSGRDVPNDFNVIIEIPMNADPIKYEVNKETGAMFVDRFMSTCMHYPCNYGYIPHTLSEDGDPVDVLVISPVPL
ISGVVVRCRPLGMLQMTDEAGGDAKVLAVPIDKLCALYRGVKSHADLSELTRSQIAHFFEHYKDLEPGKWVKITGWAGVT
EAEVEITSGVNRYNAAAKKPMF

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=172, Percent_Identity=63.3720930232558, Blast_Score=233, Evalue=8e-63,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 20177; Mature: 20177

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDRVSSGRDVPNDFNVIIEIPMNADPIKYEVNKETGAMFVDRFMSTCMHYPCNYGYIP
CCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCC
HTLSEDGDPVDVLVISPVPLISGVVVRCRPLGMLQMTDEAGGDAKVLAVPIDKLCALYRG
CCCCCCCCCEEEEEECCCHHHHCCEEEECCCCEEEEECCCCCCEEEEEECHHHHHHHHHH
VKSHADLSELTRSQIAHFFEHYKDLEPGKWVKITGWAGVTEAEVEITSGVNRYNAAAKKP
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHCCC
MF
CC
>Mature Secondary Structure
MNLDRVSSGRDVPNDFNVIIEIPMNADPIKYEVNKETGAMFVDRFMSTCMHYPCNYGYIP
CCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCC
HTLSEDGDPVDVLVISPVPLISGVVVRCRPLGMLQMTDEAGGDAKVLAVPIDKLCALYRG
CCCCCCCCCEEEEEECCCHHHHCCEEEECCCCEEEEECCCCCCEEEEEECHHHHHHHHHH
VKSHADLSELTRSQIAHFFEHYKDLEPGKWVKITGWAGVTEAEVEITSGVNRYNAAAKKP
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHCCC
MF
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9423859 [H]