Click here to switch to the map view.

The map label for this gene is yegE [C]

Identifier: 82703159

GI number: 82703159

Start: 2333764

End: 2335062

Strand: Direct

Name: yegE [C]

Synonym: Nmul_A2039

Alternate gene names: 82703159

Gene position: 2333764-2335062 (Clockwise)

Preceding gene: 82703157

Following gene: 82703160

Centisome position: 73.29

GC content: 52.27

Gene sequence:

>1299_bases
ATGATAGCGCCCTCACGCAATTTATTACTCTGCAATAAAGGAAAGACCGAATTGAACCATTCGTTCTCCATGCTGCAAGC
CATCGTAGAATCGACGCCCTATGGGCTTCTGGTGACCAACAAGCACGGGCACTTGCTTTGCTATAACCAGCCCTATATGG
ATATGTGGCGCATTCCCCCTGAGGTCATGGTCAATGCGAGACACCAGATAATTTTCGGGCATTACTCCAGTCAATTAAGA
GATCCACAACAATTCCTTCACTCAACCGAGGTAATTTATGGCACGTGGTTGCCCGAAAGTTTCGACATCCTCGAATTCCT
CGATGGGCGGGCATTCGAACGCCATACAAAAGCCACGACCTTGGAAGGGCCAAACATGGTGCGTGTTTGGAGCTTCAAGG
ACATCACTGAACGCAGGCAGGCGGAGGCCTATAAAGCGCAGTTGGCCGCAATGGTCGAGTCCTCGGACGATGCAATCATT
GTCAAGGACCTGAACGCCATTATCACAAGCTGGAATGCCGGGGCGGAACGGATTTTCGGGTACCAGGCAAGCGAAATAAC
AGGCTCTTCCATACTGGCCTTAATTCCCCCGGAGCGTCATGAAGAAGAGAAGGGGATCATGAGCCTCGTCAAGAGCGGGA
ACCGCGTGGACCATTTTGAAACCATGTGGTGGGGAAAGGGCAAGAAACCGATTGATGTCTCGGTCACGACATCGGCAGTG
AAGGATAGTGACGGCAATATTGTGGGCATATCACAGATTGCGCGGGATATCACCAAGCGCAAGGAATCACAGAAACGCAT
CGAGTATCTTGCCCATTACGATCCGCTAACCGGGCTGCCCAATCGCGCGTTGCTCGCAGACAGAATGAAAACTGCCATCG
AGAATGCCAAGCGTTATTCCTTCCAGTTGGCAGTCCTGTTTGTGGACCTTGACCACTTCAAGCTAATCAATGATTCGCTT
GGTCATGAAATCGGTGACAAGCTGCTCAAGATCGTAGCCGAGCGCATGCGATCCAGGCTGCGTCAAACCGATACCGTCAG
CCGGCTGGGAGGTGACGAATTTATTATCCTGCTGAGCCGGATTAATGCAGCATCCGATGCCGCTTGCGTCGCCGAGAAAA
TTATTGCAGCACTATCCCAGCCCTACCACCTTGAACAGCATGAGTTGGGGCTGGGCGCGAGCATCGGGATCAGCATTTAT
CCGGACAGCGGCAAGGATACCAGCAGCTTGTTGCGCAGTGCCGATGAAGCGATGTACTCTGCCAAAGGACAGGGTAGGAA
CCGCTATCATGGTCCGTAG

Upstream 100 bases:

>100_bases
TACCGAACAGCATGAGCCACCGCTTGGTATTACCCTAATCTCCAATGTGTAATGCAATGCCGTGGTTACTGAACAGAATA
GTTGCAGGCAACTTTTCCCG

Downstream 100 bases:

>100_bases
CGCCAGTGATTGAACAAGGACCTGGCCGACTGAATAGACGATTCGACGAAATTGGTAAAACAGTCGCGCCTCAGGTCCTG
ACACCTCAAAGAATGTTTTC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MIAPSRNLLLCNKGKTELNHSFSMLQAIVESTPYGLLVTNKHGHLLCYNQPYMDMWRIPPEVMVNARHQIIFGHYSSQLR
DPQQFLHSTEVIYGTWLPESFDILEFLDGRAFERHTKATTLEGPNMVRVWSFKDITERRQAEAYKAQLAAMVESSDDAII
VKDLNAIITSWNAGAERIFGYQASEITGSSILALIPPERHEEEKGIMSLVKSGNRVDHFETMWWGKGKKPIDVSVTTSAV
KDSDGNIVGISQIARDITKRKESQKRIEYLAHYDPLTGLPNRALLADRMKTAIENAKRYSFQLAVLFVDLDHFKLINDSL
GHEIGDKLLKIVAERMRSRLRQTDTVSRLGGDEFIILLSRINAASDAACVAEKIIAALSQPYHLEQHELGLGASIGISIY
PDSGKDTSSLLRSADEAMYSAKGQGRNRYHGP

Sequences:

>Translated_432_residues
MIAPSRNLLLCNKGKTELNHSFSMLQAIVESTPYGLLVTNKHGHLLCYNQPYMDMWRIPPEVMVNARHQIIFGHYSSQLR
DPQQFLHSTEVIYGTWLPESFDILEFLDGRAFERHTKATTLEGPNMVRVWSFKDITERRQAEAYKAQLAAMVESSDDAII
VKDLNAIITSWNAGAERIFGYQASEITGSSILALIPPERHEEEKGIMSLVKSGNRVDHFETMWWGKGKKPIDVSVTTSAV
KDSDGNIVGISQIARDITKRKESQKRIEYLAHYDPLTGLPNRALLADRMKTAIENAKRYSFQLAVLFVDLDHFKLINDSL
GHEIGDKLLKIVAERMRSRLRQTDTVSRLGGDEFIILLSRINAASDAACVAEKIIAALSQPYHLEQHELGLGASIGISIY
PDSGKDTSSLLRSADEAMYSAKGQGRNRYHGP
>Mature_432_residues
MIAPSRNLLLCNKGKTELNHSFSMLQAIVESTPYGLLVTNKHGHLLCYNQPYMDMWRIPPEVMVNARHQIIFGHYSSQLR
DPQQFLHSTEVIYGTWLPESFDILEFLDGRAFERHTKATTLEGPNMVRVWSFKDITERRQAEAYKAQLAAMVESSDDAII
VKDLNAIITSWNAGAERIFGYQASEITGSSILALIPPERHEEEKGIMSLVKSGNRVDHFETMWWGKGKKPIDVSVTTSAV
KDSDGNIVGISQIARDITKRKESQKRIEYLAHYDPLTGLPNRALLADRMKTAIENAKRYSFQLAVLFVDLDHFKLINDSL
GHEIGDKLLKIVAERMRSRLRQTDTVSRLGGDEFIILLSRINAASDAACVAEKIIAALSQPYHLEQHELGLGASIGISIY
PDSGKDTSSLLRSADEAMYSAKGQGRNRYHGP

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=400, Percent_Identity=27, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1787541, Length=284, Percent_Identity=30.2816901408451, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87081977, Length=167, Percent_Identity=35.3293413173653, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786584, Length=171, Percent_Identity=30.9941520467836, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI145693134, Length=157, Percent_Identity=37.5796178343949, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI87082007, Length=179, Percent_Identity=34.6368715083799, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787802, Length=169, Percent_Identity=33.1360946745562, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787816, Length=160, Percent_Identity=38.125, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=31.5151515151515, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081881, Length=182, Percent_Identity=31.8681318681319, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081921, Length=202, Percent_Identity=28.2178217821782, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788956, Length=157, Percent_Identity=34.3949044585987, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081974, Length=156, Percent_Identity=30.1282051282051, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788085, Length=165, Percent_Identity=27.8787878787879, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 48499; Mature: 48499

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAPSRNLLLCNKGKTELNHSFSMLQAIVESTPYGLLVTNKHGHLLCYNQPYMDMWRIPP
CCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCHHHHCCCH
EVMVNARHQIIFGHYSSQLRDPQQFLHSTEVIYGTWLPESFDILEFLDGRAFERHTKATT
HHHHCCCEEEEEECCHHHCCCHHHHHHHCCEEEEECCCCCHHHHHHHCCCHHHHHCCCEE
LEGPNMVRVWSFKDITERRQAEAYKAQLAAMVESSDDAIIVKDLNAIITSWNAGAERIFG
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCHHHHCC
YQASEITGSSILALIPPERHEEEKGIMSLVKSGNRVDHFETMWWGKGKKPIDVSVTTSAV
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEEEEHHE
KDSDGNIVGISQIARDITKRKESQKRIEYLAHYDPLTGLPNRALLADRMKTAIENAKRYS
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHE
FQLAVLFVDLDHFKLINDSLGHEIGDKLLKIVAERMRSRLRQTDTVSRLGGDEFIILLSR
EEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
INAASDAACVAEKIIAALSQPYHLEQHELGLGASIGISIYPDSGKDTSSLLRSADEAMYS
CCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
AKGQGRNRYHGP
CCCCCCCCCCCC
>Mature Secondary Structure
MIAPSRNLLLCNKGKTELNHSFSMLQAIVESTPYGLLVTNKHGHLLCYNQPYMDMWRIPP
CCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCHHHHCCCH
EVMVNARHQIIFGHYSSQLRDPQQFLHSTEVIYGTWLPESFDILEFLDGRAFERHTKATT
HHHHCCCEEEEEECCHHHCCCHHHHHHHCCEEEEECCCCCHHHHHHHCCCHHHHHCCCEE
LEGPNMVRVWSFKDITERRQAEAYKAQLAAMVESSDDAIIVKDLNAIITSWNAGAERIFG
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCHHHHCC
YQASEITGSSILALIPPERHEEEKGIMSLVKSGNRVDHFETMWWGKGKKPIDVSVTTSAV
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEEEEHHE
KDSDGNIVGISQIARDITKRKESQKRIEYLAHYDPLTGLPNRALLADRMKTAIENAKRYS
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHE
FQLAVLFVDLDHFKLINDSLGHEIGDKLLKIVAERMRSRLRQTDTVSRLGGDEFIILLSR
EEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
INAASDAACVAEKIIAALSQPYHLEQHELGLGASIGISIYPDSGKDTSSLLRSADEAMYS
CCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
AKGQGRNRYHGP
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]