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The map label for this gene is atoS [C]

Identifier: 82703136

GI number: 82703136

Start: 2313198

End: 2314814

Strand: Reverse

Name: atoS [C]

Synonym: Nmul_A2015

Alternate gene names: 82703136

Gene position: 2314814-2313198 (Counterclockwise)

Preceding gene: 82703142

Following gene: 82703135

Centisome position: 72.7

GC content: 52.2

Gene sequence:

>1617_bases
ATGACACTGTCCTCCCTTTCTATCGAGTCATATGCTGAATCAGAACGCTTTCAGCTATTCGTTGCCAGCGTAACTGACTA
CGCGCTTTACATGCTCAACCCTGAAGGCCGCGTCTGCAGTTGGAATGCTGGTGCGCAGAGGTTTAAAGGCTATACGGCTG
AAGAAATCATAGGTCAGCACTTCTCCCGGTTTTATACAGAGGAAGACAGGGCGGCCAATATTCCATTCAAGGCCTTGCAA
ACGGCAGCCAAAGAGGGAAGATTCGAAGATGAAGGCTGGCGCGTGCGCAAGGATGGCAATCGGTTCTGGGCCAGCATCGT
CATTGATCCAATTCGGGATCCCGAGGGCATGCTGATTGGTTTCGCTAAAATCACCCGTGATATTACCGCGCGCAAGAAGG
CAACCGAGGCTCTGCACGCCAGTGAGGAGCAATTCCGGTTACTGGTCGAGGGCGTGACGGACTACGCGCTCTACATGCTG
TCGGTAGATGGCACCATTACCAATTGGAATCCAGGGGCACGTCGGATTACTGGCTTCGATCAAACTGAAGCCGTTGGCAC
TCATTTCTCCCGCTTTTATATACAGGAAGACAAGGCCAAGGACTTGCCATTGGTGGCATTACAGACTGCGGAAGCGGATG
GTCGCTTTGAAGGCGAAGGCTGGCGGGTACGGAAAGACGGCTCCAGGTTTTGGGCAAATGTAGTGATAGACCCAATTAGA
AACGCTCTTGGCGAATTGATTGGTTTTGCAAAAATCACGCGCGATATCACGGGAAAGCGAGAGGCCGAGCAGGCGCTGGA
GCGTGCCAAAGAAGCCTTGTTCCAGTCCCAGAAGCTGGAAGCGATCGGCAAATTGACGGGCGGGATTGCTCACGACTTCA
ATAACCTGCTTAACGTCATTGTCAACGGGATTGAAATCATTGCAAAGCAAGCACAGACGCCAACTTCCACCCGGATGCTC
GAAAGCATGCAGCGCGCAGCCGCTCAGGGGACGATGTTAACGCAACAATTGTTGACGTTTGCTCGCAAGCAACCCTTAAA
GCAAGATAAGTACAATTTGAATCACGTCATACGTTCTTTTGAACCGGTACTTCGCAGAGCCAATAAAGGTTCTGTTGAGT
TTGATGTGAAACTTGATCCGCTTTTACCACCGGTAATCATCGATGCGCCGCACTTCGAGGCGGCATTATTAAACCTGGTT
ATCAATGCGCGTGACGCTACGCCCGATGGGGGCGCTATTACGTTGAGTACTGAACAGCTCGAACTGGATGAAAAGGAAAT
CAATGAGCTGCCAGCAGGACGCTATGTGAAAGTTACTGTGAAAGATACCGGTACAGGGATGCTGCCGGAAGTAGCGGCCC
AAGCCGTGGAGCCGTTCTTTACCACTAAGGAGGTTGGCAAAGGGTCAGGGCTGGGGCTGAGTCAGGTGTACGGGACGATC
AAGCAATTCGGCGGGGATATGGTAATTGAAACGGCGGTGGGCAAAGGCACTGCTATTTCCCTATTCGTGCCAGCGCTGGA
AGGGGATACGAATGAAGGTTCCGGGGGCCTGGCAAGCGGAAATGAGAAGGCATTGGTGGTGGATGATCAGGCGGATCTTC
TGGAGATCACCACGTAA

Upstream 100 bases:

>100_bases
AGAACTGAGGTTCCCAGGTACCCTCCATTTCGGAAACACGCATGATGAGTAAGCTTTCCTTAGGCAAATAATCATTAGCT
TGCTTTATATGAAGGTAAAA

Downstream 100 bases:

>100_bases
CCTTCTTCCCGATATCAAAGTAATCTTGGCTTCGGGTTGTACCTTTCCTGCATCAAGAGCTGAAAATCCTCCCATAGAAA
ACTTTAGATTTATAAGGAAG

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 538; Mature: 537

Protein sequence:

>538_residues
MTLSSLSIESYAESERFQLFVASVTDYALYMLNPEGRVCSWNAGAQRFKGYTAEEIIGQHFSRFYTEEDRAANIPFKALQ
TAAKEGRFEDEGWRVRKDGNRFWASIVIDPIRDPEGMLIGFAKITRDITARKKATEALHASEEQFRLLVEGVTDYALYML
SVDGTITNWNPGARRITGFDQTEAVGTHFSRFYIQEDKAKDLPLVALQTAEADGRFEGEGWRVRKDGSRFWANVVIDPIR
NALGELIGFAKITRDITGKREAEQALERAKEALFQSQKLEAIGKLTGGIAHDFNNLLNVIVNGIEIIAKQAQTPTSTRML
ESMQRAAAQGTMLTQQLLTFARKQPLKQDKYNLNHVIRSFEPVLRRANKGSVEFDVKLDPLLPPVIIDAPHFEAALLNLV
INARDATPDGGAITLSTEQLELDEKEINELPAGRYVKVTVKDTGTGMLPEVAAQAVEPFFTTKEVGKGSGLGLSQVYGTI
KQFGGDMVIETAVGKGTAISLFVPALEGDTNEGSGGLASGNEKALVVDDQADLLEITT

Sequences:

>Translated_538_residues
MTLSSLSIESYAESERFQLFVASVTDYALYMLNPEGRVCSWNAGAQRFKGYTAEEIIGQHFSRFYTEEDRAANIPFKALQ
TAAKEGRFEDEGWRVRKDGNRFWASIVIDPIRDPEGMLIGFAKITRDITARKKATEALHASEEQFRLLVEGVTDYALYML
SVDGTITNWNPGARRITGFDQTEAVGTHFSRFYIQEDKAKDLPLVALQTAEADGRFEGEGWRVRKDGSRFWANVVIDPIR
NALGELIGFAKITRDITGKREAEQALERAKEALFQSQKLEAIGKLTGGIAHDFNNLLNVIVNGIEIIAKQAQTPTSTRML
ESMQRAAAQGTMLTQQLLTFARKQPLKQDKYNLNHVIRSFEPVLRRANKGSVEFDVKLDPLLPPVIIDAPHFEAALLNLV
INARDATPDGGAITLSTEQLELDEKEINELPAGRYVKVTVKDTGTGMLPEVAAQAVEPFFTTKEVGKGSGLGLSQVYGTI
KQFGGDMVIETAVGKGTAISLFVPALEGDTNEGSGGLASGNEKALVVDDQADLLEITT
>Mature_537_residues
TLSSLSIESYAESERFQLFVASVTDYALYMLNPEGRVCSWNAGAQRFKGYTAEEIIGQHFSRFYTEEDRAANIPFKALQT
AAKEGRFEDEGWRVRKDGNRFWASIVIDPIRDPEGMLIGFAKITRDITARKKATEALHASEEQFRLLVEGVTDYALYMLS
VDGTITNWNPGARRITGFDQTEAVGTHFSRFYIQEDKAKDLPLVALQTAEADGRFEGEGWRVRKDGSRFWANVVIDPIRN
ALGELIGFAKITRDITGKREAEQALERAKEALFQSQKLEAIGKLTGGIAHDFNNLLNVIVNGIEIIAKQAQTPTSTRMLE
SMQRAAAQGTMLTQQLLTFARKQPLKQDKYNLNHVIRSFEPVLRRANKGSVEFDVKLDPLLPPVIIDAPHFEAALLNLVI
NARDATPDGGAITLSTEQLELDEKEINELPAGRYVKVTVKDTGTGMLPEVAAQAVEPFFTTKEVGKGSGLGLSQVYGTIK
QFGGDMVIETAVGKGTAISLFVPALEGDTNEGSGGLASGNEKALVVDDQADLLEITT

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=378, Percent_Identity=26.4550264550265, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=27.0042194092827, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=25.7261410788382, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59245; Mature: 59114

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSSLSIESYAESERFQLFVASVTDYALYMLNPEGRVCSWNAGAQRFKGYTAEEIIGQH
CCCCCCCHHHHHCCCCEEEEEEECCCEEEEEECCCCCEEECCCCHHHHCCCCHHHHHHHH
FSRFYTEEDRAANIPFKALQTAAKEGRFEDEGWRVRKDGNRFWASIVIDPIRDPEGMLIG
HHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCEEEEEEEEECCCCCCCCEEE
FAKITRDITARKKATEALHASEEQFRLLVEGVTDYALYMLSVDGTITNWNPGARRITGFD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEEEECCEEECCCCCCCEECCCC
QTEAVGTHFSRFYIQEDKAKDLPLVALQTAEADGRFEGEGWRVRKDGSRFWANVVIDPIR
CHHHHHHHHHHEEEECCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHH
NALGELIGFAKITRDITGKREAEQALERAKEALFQSQKLEAIGKLTGGIAHDFNNLLNVI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VNGIEIIAKQAQTPTSTRMLESMQRAAAQGTMLTQQLLTFARKQPLKQDKYNLNHVIRSF
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EPVLRRANKGSVEFDVKLDPLLPPVIIDAPHFEAALLNLVINARDATPDGGAITLSTEQL
HHHHHCCCCCCEEEEEEECCCCCCEEEECCCHHHHHHHHHEECCCCCCCCCEEEEEHHHH
ELDEKEINELPAGRYVKVTVKDTGTGMLPEVAAQAVEPFFTTKEVGKGSGLGLSQVYGTI
CCCHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHH
KQFGGDMVIETAVGKGTAISLFVPALEGDTNEGSGGLASGNEKALVVDDQADLLEITT
HHCCCCEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEEECC
>Mature Secondary Structure 
TLSSLSIESYAESERFQLFVASVTDYALYMLNPEGRVCSWNAGAQRFKGYTAEEIIGQH
CCCCCCHHHHHCCCCEEEEEEECCCEEEEEECCCCCEEECCCCHHHHCCCCHHHHHHHH
FSRFYTEEDRAANIPFKALQTAAKEGRFEDEGWRVRKDGNRFWASIVIDPIRDPEGMLIG
HHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCEEEEEEEEECCCCCCCCEEE
FAKITRDITARKKATEALHASEEQFRLLVEGVTDYALYMLSVDGTITNWNPGARRITGFD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEEEECCEEECCCCCCCEECCCC
QTEAVGTHFSRFYIQEDKAKDLPLVALQTAEADGRFEGEGWRVRKDGSRFWANVVIDPIR
CHHHHHHHHHHEEEECCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHH
NALGELIGFAKITRDITGKREAEQALERAKEALFQSQKLEAIGKLTGGIAHDFNNLLNVI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VNGIEIIAKQAQTPTSTRMLESMQRAAAQGTMLTQQLLTFARKQPLKQDKYNLNHVIRSF
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EPVLRRANKGSVEFDVKLDPLLPPVIIDAPHFEAALLNLVINARDATPDGGAITLSTEQL
HHHHHCCCCCCEEEEEEECCCCCCEEEECCCHHHHHHHHHEECCCCCCCCCEEEEEHHHH
ELDEKEINELPAGRYVKVTVKDTGTGMLPEVAAQAVEPFFTTKEVGKGSGLGLSQVYGTI
CCCHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHH
KQFGGDMVIETAVGKGTAISLFVPALEGDTNEGSGGLASGNEKALVVDDQADLLEITT
HHCCCCEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA