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The map label for this gene is yciR [C]

Identifier: 82702732

GI number: 82702732

Start: 1840420

End: 1842486

Strand: Reverse

Name: yciR [C]

Synonym: Nmul_A1605

Alternate gene names: 82702732

Gene position: 1842486-1840420 (Counterclockwise)

Preceding gene: 82702736

Following gene: 82702731

Centisome position: 57.86

GC content: 53.51

Gene sequence:

>2067_bases
ATGAAAGAAACGCTGGAACTGAGCCAATCACTCTCCTTGCTGGAGACAGTCTTAAAGGCGACGGCTGACGGCCTCCTTGT
GGCGGACAAGCTGGGCAAGGTGCTTTGCTACAACCAGCTTTACGTGAATATGTGGCACATTCCAGGTGAACTCCTGGCTC
ATGCGAGACACCAGGCAATCCTCGACTATTGCGCCGGGCAATTAAGAGATCCCGAGCAATTCCTGCACTCGACCGAAGAA
ATTTATGGCACTTGGACACCGGAAAGCTTTGATATCTTCGAATTTTGTGATGGGCGGGTATTTGAGCGGTATACAAAAAC
CAAAACCCTTGAAGGGTCAAACATGGTTCGCGTTTGGAGCTTCAGGGATATTACTGAACGAAGACAGGGGGAGAGCTACA
AAGCGCAGTTAGCGGCAATCCTCGACTCCTCGAACGATGCGCTCATTATCAAGGATCTCAATGGCATCATTAGCGGGTGG
AACACCGGTGCGGAACGGATTTTTGGTTACCGTGCGAGCGAAATCATAGGTAGTCCGATCTCCCGACTAATTCCACCCGA
TCGCCTGGAGGAAGAGGACAGAATCATGAACCTCGTCAAGAGCGGAAAACAAACAAATCATCTGGAAACCGTGCGATGGG
GGAAGGGCAAGAAACCGATTGATGTCTCCGTCACGATATCCCCGGTGAAGGATAACGCAGGCCACATTGTCGGTGCATAC
AAGATAGCGCACGATATCACTCAGCGCAAGGAATCGCTAAAACGTATCGAGTATCTCGCCCATTACGATTTGCTGACCGG
GCTGCCCAACCGCGCGCTGTTCACCGACCGCATGAGGATCGCGATCGAGAACGCCAGCCGCTATGCCTTCCGGCTGGCAT
TACTATTCGTGGACCTCGATCGCTTCAAGCTGATCAACGATTCGCTTGGTCATGCAATCGGCGACAAGCTGCTCAGGGCA
GTTGCAGAGCGCATGCAGTCCACGGTTCGCCAGGCGGATACAGTCAGTCGGCTGGGGGGGGATGAGTTCGTTGTCCTGCT
GGGCCGGATTCATACAGCGACGGAGGCGGCGCGAGTTGCCGAGAAGCTTATTGCAGTCTTGTCTCAGCCCTATCAAATAG
AACAGCATGAACTCTTGCTGACCGCAAGCGTCGGGATCAGCATTTATCCGGATAGCGGTAAGGACGTCAACAGCTTGATG
CGCAATGCCGACGTTTCGATGTATTCGGCCAAGGGGCAGGGCAGGAACCGCTACCAGTTCTATTCTGAAGATTTGACTTC
CGGCGCAGACGAGCGGCTCAGGCTGGAATACGACCTGCGCAGCGCTCTTGCGCGTGACGAAATTTTCCCGGTCTACCAGC
CACAGCTGGAGCTTGCTACCGGACGCGTGGTAGGCGTGGAGGCGCTCATGCGCTGGAAGCACCCCGAGCGAGGGCTAGTC
TCCCCTGCAAGCTTTATTCCCGTAGCCGAGGACAGCGGTTTGATTCTGTCTCTGGGGGAGCACATCCTGAGGGAATCCTG
CCTGCAGGCACGCCAATGGCATGAGCAGCAGGGATTCGAGGGAACAATCGCGGTAAACGTTTCAGCAGTACAATTCCGTC
AGAATGATTTCACGGATGTTGTACTGCGCGCACTTGCAGACAGCGGTCTTTCGCCAGAATGCCTGGAACTCGAGTTGACC
GAAAGTGTGGTGATGCATGGAGTGGAATCGGCTACACAGAAAATGTGCTTCCTGGAGTCCCGGGGTATAAAACTGGCTAT
TGACGATTTCGGTACCGGCTATTCCAGTTTGTCCTATTTGCGGCAATTTGCCATTGACCGGCTAAAAATAGATCGAAGCT
TCGTTCGTGATCTCCCCCAGGACACTGATGCCAAAGCTATTATTCGCGCCATTGTGGGAATGGGGCGCAGCCTTGGTTTA
CGCGTGATAGTTGAAGGTGTGGAGACGGAAGGGCAAGCGGAGTATTTGCGAAGCGTTCAATGCGATGAAAGCCAAGGCTA
TCTGTATGCAAGGCCCATGAGGCCAGATGATTTTGAGGCTTGGGTAAAAACTAGGAATCCGGTTTAG

Upstream 100 bases:

>100_bases
TGGATCCAGTTAATCTGCAGAGCATTTCTGGAAGCACGCGGATTTATTCGTTCCAATCAAGAAAAGAAAGGAAAATCGGG
CATAAAAGAGGCGGAAAAGC

Downstream 100 bases:

>100_bases
ACGCTCGCGCTATTATTCGTTAACCCTTTTGTGGCGGAAACCGGTTTTTCAAGGAGGGTTGCCGGATCTACTGGATTTGC
TGAAGACGGCAAGCGTACCC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 688; Mature: 688

Protein sequence:

>688_residues
MKETLELSQSLSLLETVLKATADGLLVADKLGKVLCYNQLYVNMWHIPGELLAHARHQAILDYCAGQLRDPEQFLHSTEE
IYGTWTPESFDIFEFCDGRVFERYTKTKTLEGSNMVRVWSFRDITERRQGESYKAQLAAILDSSNDALIIKDLNGIISGW
NTGAERIFGYRASEIIGSPISRLIPPDRLEEEDRIMNLVKSGKQTNHLETVRWGKGKKPIDVSVTISPVKDNAGHIVGAY
KIAHDITQRKESLKRIEYLAHYDLLTGLPNRALFTDRMRIAIENASRYAFRLALLFVDLDRFKLINDSLGHAIGDKLLRA
VAERMQSTVRQADTVSRLGGDEFVVLLGRIHTATEAARVAEKLIAVLSQPYQIEQHELLLTASVGISIYPDSGKDVNSLM
RNADVSMYSAKGQGRNRYQFYSEDLTSGADERLRLEYDLRSALARDEIFPVYQPQLELATGRVVGVEALMRWKHPERGLV
SPASFIPVAEDSGLILSLGEHILRESCLQARQWHEQQGFEGTIAVNVSAVQFRQNDFTDVVLRALADSGLSPECLELELT
ESVVMHGVESATQKMCFLESRGIKLAIDDFGTGYSSLSYLRQFAIDRLKIDRSFVRDLPQDTDAKAIIRAIVGMGRSLGL
RVIVEGVETEGQAEYLRSVQCDESQGYLYARPMRPDDFEAWVKTRNPV

Sequences:

>Translated_688_residues
MKETLELSQSLSLLETVLKATADGLLVADKLGKVLCYNQLYVNMWHIPGELLAHARHQAILDYCAGQLRDPEQFLHSTEE
IYGTWTPESFDIFEFCDGRVFERYTKTKTLEGSNMVRVWSFRDITERRQGESYKAQLAAILDSSNDALIIKDLNGIISGW
NTGAERIFGYRASEIIGSPISRLIPPDRLEEEDRIMNLVKSGKQTNHLETVRWGKGKKPIDVSVTISPVKDNAGHIVGAY
KIAHDITQRKESLKRIEYLAHYDLLTGLPNRALFTDRMRIAIENASRYAFRLALLFVDLDRFKLINDSLGHAIGDKLLRA
VAERMQSTVRQADTVSRLGGDEFVVLLGRIHTATEAARVAEKLIAVLSQPYQIEQHELLLTASVGISIYPDSGKDVNSLM
RNADVSMYSAKGQGRNRYQFYSEDLTSGADERLRLEYDLRSALARDEIFPVYQPQLELATGRVVGVEALMRWKHPERGLV
SPASFIPVAEDSGLILSLGEHILRESCLQARQWHEQQGFEGTIAVNVSAVQFRQNDFTDVVLRALADSGLSPECLELELT
ESVVMHGVESATQKMCFLESRGIKLAIDDFGTGYSSLSYLRQFAIDRLKIDRSFVRDLPQDTDAKAIIRAIVGMGRSLGL
RVIVEGVETEGQAEYLRSVQCDESQGYLYARPMRPDDFEAWVKTRNPV
>Mature_688_residues
MKETLELSQSLSLLETVLKATADGLLVADKLGKVLCYNQLYVNMWHIPGELLAHARHQAILDYCAGQLRDPEQFLHSTEE
IYGTWTPESFDIFEFCDGRVFERYTKTKTLEGSNMVRVWSFRDITERRQGESYKAQLAAILDSSNDALIIKDLNGIISGW
NTGAERIFGYRASEIIGSPISRLIPPDRLEEEDRIMNLVKSGKQTNHLETVRWGKGKKPIDVSVTISPVKDNAGHIVGAY
KIAHDITQRKESLKRIEYLAHYDLLTGLPNRALFTDRMRIAIENASRYAFRLALLFVDLDRFKLINDSLGHAIGDKLLRA
VAERMQSTVRQADTVSRLGGDEFVVLLGRIHTATEAARVAEKLIAVLSQPYQIEQHELLLTASVGISIYPDSGKDVNSLM
RNADVSMYSAKGQGRNRYQFYSEDLTSGADERLRLEYDLRSALARDEIFPVYQPQLELATGRVVGVEALMRWKHPERGLV
SPASFIPVAEDSGLILSLGEHILRESCLQARQWHEQQGFEGTIAVNVSAVQFRQNDFTDVVLRALADSGLSPECLELELT
ESVVMHGVESATQKMCFLESRGIKLAIDDFGTGYSSLSYLRQFAIDRLKIDRSFVRDLPQDTDAKAIIRAIVGMGRSLGL
RVIVEGVETEGQAEYLRSVQCDESQGYLYARPMRPDDFEAWVKTRNPV

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=568, Percent_Identity=33.4507042253521, Blast_Score=294, Evalue=1e-80,
Organism=Escherichia coli, GI87081921, Length=441, Percent_Identity=33.1065759637188, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI226510982, Length=452, Percent_Identity=27.8761061946903, Blast_Score=188, Evalue=9e-49,
Organism=Escherichia coli, GI1788381, Length=586, Percent_Identity=25.938566552901, Blast_Score=169, Evalue=8e-43,
Organism=Escherichia coli, GI1787055, Length=476, Percent_Identity=26.0504201680672, Blast_Score=155, Evalue=8e-39,
Organism=Escherichia coli, GI87081845, Length=237, Percent_Identity=37.5527426160338, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1788502, Length=252, Percent_Identity=32.1428571428571, Blast_Score=150, Evalue=4e-37,
Organism=Escherichia coli, GI87081980, Length=259, Percent_Identity=33.976833976834, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1790496, Length=257, Percent_Identity=30.7392996108949, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1786507, Length=280, Percent_Identity=33.9285714285714, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI87081743, Length=248, Percent_Identity=34.6774193548387, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1788849, Length=435, Percent_Identity=26.2068965517241, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI87081881, Length=181, Percent_Identity=35.3591160220994, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI87082096, Length=206, Percent_Identity=30.5825242718447, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=36.5853658536585, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI145693134, Length=165, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=32.5842696629214, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1787802, Length=181, Percent_Identity=30.3867403314917, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI87082007, Length=165, Percent_Identity=34.5454545454545, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788956, Length=155, Percent_Identity=34.1935483870968, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1787262, Length=172, Percent_Identity=30.2325581395349, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI87081977, Length=167, Percent_Identity=31.1377245508982, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787410, Length=221, Percent_Identity=25.3393665158371, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788085, Length=165, Percent_Identity=27.8787878787879, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081974, Length=85, Percent_Identity=34.1176470588235, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 77415; Mature: 77415

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKETLELSQSLSLLETVLKATADGLLVADKLGKVLCYNQLYVNMWHIPGELLAHARHQAI
CCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHCHHHEEHHHEEEEECCCHHHHHHHHHHHH
LDYCAGQLRDPEQFLHSTEEIYGTWTPESFDIFEFCDGRVFERYTKTKTLEGSNMVRVWS
HHHHHHCCCCHHHHHHHHHHHEECCCCCCCCHHHHHCCHHHHHHHHHCEECCCCEEEEEE
FRDITERRQGESYKAQLAAILDSSNDALIIKDLNGIISGWNTGAERIFGYRASEIIGSPI
CHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCHHHCCCCCCHHHHHCCHHHHHHCCCH
SRLIPPDRLEEEDRIMNLVKSGKQTNHLETVRWGKGKKPIDVSVTISPVKDNAGHIVGAY
HHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCCEEEEEEEEECCCCCCCEEEHH
KIAHDITQRKESLKRIEYLAHYDLLTGLPNRALFTDRMRIAIENASRYAFRLALLFVDLD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHEEEEECCHHHHHHHHHHHHHHH
RFKLINDSLGHAIGDKLLRAVAERMQSTVRQADTVSRLGGDEFVVLLGRIHTATEAARVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHH
EKLIAVLSQPYQIEQHELLLTASVGISIYPDSGKDVNSLMRNADVSMYSAKGQGRNRYQF
HHHHHHHCCCCEECCCEEEEEEECCEEEECCCCCHHHHHHHCCCCEEEECCCCCCCCCEE
YSEDLTSGADERLRLEYDLRSALARDEIFPVYQPQLELATGRVVGVEALMRWKHPERGLV
HHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCC
SPASFIPVAEDSGLILSLGEHILRESCLQARQWHEQQGFEGTIAVNVSAVQFRQNDFTDV
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHH
VLRALADSGLSPECLELELTESVVMHGVESATQKMCFLESRGIKLAIDDFGTGYSSLSYL
HHHHHHCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
RQFAIDRLKIDRSFVRDLPQDTDAKAIIRAIVGMGRSLGLRVIVEGVETEGQAEYLRSVQ
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCC
CDESQGYLYARPMRPDDFEAWVKTRNPV
CCCCCCEEEECCCCCCCHHHHHHCCCCC
>Mature Secondary Structure
MKETLELSQSLSLLETVLKATADGLLVADKLGKVLCYNQLYVNMWHIPGELLAHARHQAI
CCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHCHHHEEHHHEEEEECCCHHHHHHHHHHHH
LDYCAGQLRDPEQFLHSTEEIYGTWTPESFDIFEFCDGRVFERYTKTKTLEGSNMVRVWS
HHHHHHCCCCHHHHHHHHHHHEECCCCCCCCHHHHHCCHHHHHHHHHCEECCCCEEEEEE
FRDITERRQGESYKAQLAAILDSSNDALIIKDLNGIISGWNTGAERIFGYRASEIIGSPI
CHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCHHHCCCCCCHHHHHCCHHHHHHCCCH
SRLIPPDRLEEEDRIMNLVKSGKQTNHLETVRWGKGKKPIDVSVTISPVKDNAGHIVGAY
HHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCCEEEEEEEEECCCCCCCEEEHH
KIAHDITQRKESLKRIEYLAHYDLLTGLPNRALFTDRMRIAIENASRYAFRLALLFVDLD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHEEEEECCHHHHHHHHHHHHHHH
RFKLINDSLGHAIGDKLLRAVAERMQSTVRQADTVSRLGGDEFVVLLGRIHTATEAARVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHH
EKLIAVLSQPYQIEQHELLLTASVGISIYPDSGKDVNSLMRNADVSMYSAKGQGRNRYQF
HHHHHHHCCCCEECCCEEEEEEECCEEEECCCCCHHHHHHHCCCCEEEECCCCCCCCCEE
YSEDLTSGADERLRLEYDLRSALARDEIFPVYQPQLELATGRVVGVEALMRWKHPERGLV
HHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCC
SPASFIPVAEDSGLILSLGEHILRESCLQARQWHEQQGFEGTIAVNVSAVQFRQNDFTDV
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHH
VLRALADSGLSPECLELELTESVVMHGVESATQKMCFLESRGIKLAIDDFGTGYSSLSYL
HHHHHHCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
RQFAIDRLKIDRSFVRDLPQDTDAKAIIRAIVGMGRSLGLRVIVEGVETEGQAEYLRSVQ
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCC
CDESQGYLYARPMRPDDFEAWVKTRNPV
CCCCCCEEEECCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]