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The map label for this gene is 82702687

Identifier: 82702687

GI number: 82702687

Start: 1788374

End: 1789318

Strand: Reverse

Name: 82702687

Synonym: Nmul_A1558

Alternate gene names: NA

Gene position: 1789318-1788374 (Counterclockwise)

Preceding gene: 82702694

Following gene: 82702686

Centisome position: 56.19

GC content: 55.13

Gene sequence:

>945_bases
ATGCGACCCGCTTCCCATACCGCTTTCATTTCCCATCCGGATTGCCTGTTGCACGAAATGGATTTTTATCATCCTGAGAG
TCCAGCGCGGCTGAAGGCGATCGAGGACGAGCTGTCTGCTTCAGGACTGATGGATAAACTTAGACGCTATCAGGCGCCAT
TAGCGACTGTCGGCCAACTGGAGCGTGTGCATACACGGGAGCATATTGCAAGGTTGCACGCTGCAGCATCCCGCGCGGCT
TCGGGAGGTTTCGTCTACCTTGATCCGGATACCGCCATGAACCGCCACAGCCTTGGAGCAGCTTATCGGGCCGCGGGGGC
TGTTGTCCTCGCTGCCGATCTCGTGATAGAAGGAGCGGCGGAAAATGCATTTTGCAGTATTCGTCCCCCGGGTCACCACG
CGGAACGCGGATACCCGATGGGTTTCTGCCTGTTCAACAATATTGCCGTAGCGGTTGCTCACGCGCTTGAAACACATGCT
CTGAAACGTGTCGCGGTGGTGGACTTCGACGTGCATCACGGCAACGGTACGGAAGATATCTTTCAGCACGATCCCCGCGT
CATGATGGTCTCGACATTTCAGCACCCGTTCTATCCATATAGCGGCATCGCAGGCCGTTCAGAGCGAATGGTCAACATCC
CGCTGCCAGCGGGGAGCAACGGCAAGGTATTTCGCAAAGCAGTGGATGAATTCTGGTTGCCGGCGCTGGAAAGGTTTAAA
CCGCAAATGTTGTTTGTTTCTGCTGGTTTCGATGCTCATGCCGATGATGAGCTTGCTTCTCTGAATCTGGTGGAAGACGA
TTACGCGTGGGTAACTGAAAAAATCAAAGAGGTTGCCCGCGCTTATGCCGGGAAACGTATCGTATCGGTGCTGGAAGGCG
GGTATGCGTTGGCTGCGCTGGCACGAAGCGTGGCAGCGCATATAGAAGTCCTTATGAAGCCCTGA

Upstream 100 bases:

>100_bases
GGATTCCTGAGCCATGAGATTAGCACGGAGTGGACAGGGGTTCAATTTGCAGAAAACACATCCGGAAAAGGCAACGAGAC
GACATCAAGAGAGGTAGCCC

Downstream 100 bases:

>100_bases
CAGCTCAAAACGCGCCTTTTCAACGCCCACTCTTCCCGGCACCCCTTCGACCCTTCCGGTTTACCTGAGAGTCCTTCCTC
GAGCATCTCTTGCGCCCCGC

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MRPASHTAFISHPDCLLHEMDFYHPESPARLKAIEDELSASGLMDKLRRYQAPLATVGQLERVHTREHIARLHAAASRAA
SGGFVYLDPDTAMNRHSLGAAYRAAGAVVLAADLVIEGAAENAFCSIRPPGHHAERGYPMGFCLFNNIAVAVAHALETHA
LKRVAVVDFDVHHGNGTEDIFQHDPRVMMVSTFQHPFYPYSGIAGRSERMVNIPLPAGSNGKVFRKAVDEFWLPALERFK
PQMLFVSAGFDAHADDELASLNLVEDDYAWVTEKIKEVARAYAGKRIVSVLEGGYALAALARSVAAHIEVLMKP

Sequences:

>Translated_314_residues
MRPASHTAFISHPDCLLHEMDFYHPESPARLKAIEDELSASGLMDKLRRYQAPLATVGQLERVHTREHIARLHAAASRAA
SGGFVYLDPDTAMNRHSLGAAYRAAGAVVLAADLVIEGAAENAFCSIRPPGHHAERGYPMGFCLFNNIAVAVAHALETHA
LKRVAVVDFDVHHGNGTEDIFQHDPRVMMVSTFQHPFYPYSGIAGRSERMVNIPLPAGSNGKVFRKAVDEFWLPALERFK
PQMLFVSAGFDAHADDELASLNLVEDDYAWVTEKIKEVARAYAGKRIVSVLEGGYALAALARSVAAHIEVLMKP
>Mature_314_residues
MRPASHTAFISHPDCLLHEMDFYHPESPARLKAIEDELSASGLMDKLRRYQAPLATVGQLERVHTREHIARLHAAASRAA
SGGFVYLDPDTAMNRHSLGAAYRAAGAVVLAADLVIEGAAENAFCSIRPPGHHAERGYPMGFCLFNNIAVAVAHALETHA
LKRVAVVDFDVHHGNGTEDIFQHDPRVMMVSTFQHPFYPYSGIAGRSERMVNIPLPAGSNGKVFRKAVDEFWLPALERFK
PQMLFVSAGFDAHADDELASLNLVEDDYAWVTEKIKEVARAYAGKRIVSVLEGGYALAALARSVAAHIEVLMKP

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI20070354, Length=330, Percent_Identity=33.9393939393939, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI13128864, Length=312, Percent_Identity=32.6923076923077, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI153085395, Length=324, Percent_Identity=32.0987654320988, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI17158039, Length=353, Percent_Identity=30.5949008498584, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI30795202, Length=353, Percent_Identity=30.5949008498584, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI30795204, Length=353, Percent_Identity=30.5949008498584, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI226529806, Length=330, Percent_Identity=32.4242424242424, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI148539870, Length=328, Percent_Identity=30.7926829268293, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI169234807, Length=328, Percent_Identity=30.7926829268293, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI62750347, Length=324, Percent_Identity=29.320987654321, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI62750349, Length=324, Percent_Identity=29.320987654321, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI13128860, Length=296, Percent_Identity=24.6621621621622, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI293336691, Length=274, Percent_Identity=25.9124087591241, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI8923769, Length=291, Percent_Identity=23.0240549828179, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI13128862, Length=302, Percent_Identity=22.5165562913907, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI217272877, Length=296, Percent_Identity=25, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI209862883, Length=220, Percent_Identity=26.3636363636364, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17540334, Length=308, Percent_Identity=36.038961038961, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17540332, Length=308, Percent_Identity=36.038961038961, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI193206283, Length=308, Percent_Identity=36.038961038961, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI193209491, Length=340, Percent_Identity=31.7647058823529, Blast_Score=141, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI25154020, Length=283, Percent_Identity=28.2685512367491, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI25154022, Length=283, Percent_Identity=27.9151943462898, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17537347, Length=294, Percent_Identity=29.9319727891156, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17534739, Length=306, Percent_Identity=23.8562091503268, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17508561, Length=300, Percent_Identity=26.6666666666667, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17561978, Length=194, Percent_Identity=31.4432989690722, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193207430, Length=284, Percent_Identity=25.7042253521127, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324307, Length=323, Percent_Identity=30.6501547987616, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6325141, Length=284, Percent_Identity=26.7605633802817, Blast_Score=96, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6323999, Length=311, Percent_Identity=26.0450160771704, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6321244, Length=261, Percent_Identity=26.0536398467433, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325325, Length=273, Percent_Identity=24.1758241758242, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24642142, Length=312, Percent_Identity=32.6923076923077, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24642144, Length=312, Percent_Identity=32.6923076923077, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI281360899, Length=312, Percent_Identity=32.6923076923077, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24642146, Length=312, Percent_Identity=32.6923076923077, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI281360801, Length=329, Percent_Identity=31.9148936170213, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24641720, Length=329, Percent_Identity=31.9148936170213, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI281360799, Length=329, Percent_Identity=31.9148936170213, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24657891, Length=312, Percent_Identity=26.6025641025641, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24644244, Length=307, Percent_Identity=25.7328990228013, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24649807, Length=283, Percent_Identity=26.1484098939929, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 34430; Mature: 34430

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPASHTAFISHPDCLLHEMDFYHPESPARLKAIEDELSASGLMDKLRRYQAPLATVGQL
CCCCCCCEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ERVHTREHIARLHAAASRAASGGFVYLDPDTAMNRHSLGAAYRAAGAVVLAADLVIEGAA
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHEEEHHHHHCCCC
ENAFCSIRPPGHHAERGYPMGFCLFNNIAVAVAHALETHALKRVAVVDFDVHHGNGTEDI
CCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCHHH
FQHDPRVMMVSTFQHPFYPYSGIAGRSERMVNIPLPAGSNGKVFRKAVDEFWLPALERFK
HHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
PQMLFVSAGFDAHADDELASLNLVEDDYAWVTEKIKEVARAYAGKRIVSVLEGGYALAAL
CEEEEEECCCCCCCCCCHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ARSVAAHIEVLMKP
HHHHHHHHHHHCCC
>Mature Secondary Structure
MRPASHTAFISHPDCLLHEMDFYHPESPARLKAIEDELSASGLMDKLRRYQAPLATVGQL
CCCCCCCEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ERVHTREHIARLHAAASRAASGGFVYLDPDTAMNRHSLGAAYRAAGAVVLAADLVIEGAA
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHEEEHHHHHCCCC
ENAFCSIRPPGHHAERGYPMGFCLFNNIAVAVAHALETHALKRVAVVDFDVHHGNGTEDI
CCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCHHH
FQHDPRVMMVSTFQHPFYPYSGIAGRSERMVNIPLPAGSNGKVFRKAVDEFWLPALERFK
HHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
PQMLFVSAGFDAHADDELASLNLVEDDYAWVTEKIKEVARAYAGKRIVSVLEGGYALAAL
CEEEEEECCCCCCCCCCHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ARSVAAHIEVLMKP
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]