Click here to switch to the map view.

The map label for this gene is tbpA [C]

Identifier: 82701865

GI number: 82701865

Start: 853102

End: 854115

Strand: Reverse

Name: tbpA [C]

Synonym: Nmul_A0732

Alternate gene names: 82701865

Gene position: 854115-853102 (Counterclockwise)

Preceding gene: 82701868

Following gene: 82701864

Centisome position: 26.82

GC content: 51.68

Gene sequence:

>1014_bases
ATGCCCAGTGCGCGCCTCAATCGTTATCTTACCGCAATGATATGCTGTGTCACGCTATTTACCGCAGATGCATCCGGGGC
GGAGGACGTCGTCGTCTATTCGGCCCGCATAGAGCAGCTCATCAAACCCATGTTCGATGCTTTCACCAAGGATAGCGGCG
TTGCTGTCAAATTCGTCACCGATAAGGAAGGCCCCTTGCTCGCGCGCCTTAAGGCAGAAGGCAAAAACACTCCGGCTGAC
GTACTGCTCACCACCGATGCCGGCAACTTGTGGGAGGCGGCGCGAGAGGGATTGCTCCGCCCGGTGGAGTCAGAAATACT
CGAAACGAATGTTCCCGCTCATCTCCGAGATCCTTTGAAGCGGTGGTTCGGCTTATCGATACGCGCCCGTACCATCGTTT
ACAACACCAACAAGGTAAAACCCTCCGATCTTTCAACCTATGAAGCGCTGGCAGATCCCAAGTGGAAGAACCGCCTGTGC
ATACGCACTTCCAAGAAAGTATACAACCAGTCTCTGGTGGCAATGATGATTGCCGAGCATGGAGAACCGAAAACCGAGCA
GATCGTAAAGGGCTGGATTACCAATCTTGCAACCGATCCTCTTTCGGATGATACCAAGGCTATGGAATACGTTGCTGCAG
GGAAATGTGACGTCACTATTGTCAATACTTATTATTACGGGCGCCTGATGAAAAAGGACCCGAAACTACCGCTTGCGATT
TTCTGGCCGAACCAGGACAACAGTGGCGTCCATGTAAATATTTCGGGTGCAGGCGTGACAAAATATGCGCATCACCCTCA
AGCCGCGATCAAGCTGATCGAATTTCTATCCTCGGAAAAAGCGCAGAATCTGTTTGCCGACGTAAACATGGAGTATCCGG
TGAACTCCAAGGTCAAAACCGATCCTGCCGTAGCCGCGTGGGGCAGTTTCAAACAGAATACGATAAATGTGAATAAAGCC
GGAGAACTGCAAGCGGAAGCGGTAAAACTGATGGATCGCGCCGGCTACAAGTAA

Upstream 100 bases:

>100_bases
TTGTTCTGGCTCATCCATGATATATTAACGTGCCGCTTTGCTGATAATTATTATCATTTATAATATTAGCCTTTCTGCCT
TTATATCCGGAGTAAATCAA

Downstream 100 bases:

>100_bases
GATATAACCGGGTGATGGTCGAGTGGAGGTAGAAGCGCTTAGCGGGCCCGGGACGGGAACGGAGACGACGGATAGTCAAG
GCACAAGAAAGTGGTTTTTC

Product: extracellular solute-binding protein

Products: ADP; phosphate; thiamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MPSARLNRYLTAMICCVTLFTADASGAEDVVVYSARIEQLIKPMFDAFTKDSGVAVKFVTDKEGPLLARLKAEGKNTPAD
VLLTTDAGNLWEAAREGLLRPVESEILETNVPAHLRDPLKRWFGLSIRARTIVYNTNKVKPSDLSTYEALADPKWKNRLC
IRTSKKVYNQSLVAMMIAEHGEPKTEQIVKGWITNLATDPLSDDTKAMEYVAAGKCDVTIVNTYYYGRLMKKDPKLPLAI
FWPNQDNSGVHVNISGAGVTKYAHHPQAAIKLIEFLSSEKAQNLFADVNMEYPVNSKVKTDPAVAAWGSFKQNTINVNKA
GELQAEAVKLMDRAGYK

Sequences:

>Translated_337_residues
MPSARLNRYLTAMICCVTLFTADASGAEDVVVYSARIEQLIKPMFDAFTKDSGVAVKFVTDKEGPLLARLKAEGKNTPAD
VLLTTDAGNLWEAAREGLLRPVESEILETNVPAHLRDPLKRWFGLSIRARTIVYNTNKVKPSDLSTYEALADPKWKNRLC
IRTSKKVYNQSLVAMMIAEHGEPKTEQIVKGWITNLATDPLSDDTKAMEYVAAGKCDVTIVNTYYYGRLMKKDPKLPLAI
FWPNQDNSGVHVNISGAGVTKYAHHPQAAIKLIEFLSSEKAQNLFADVNMEYPVNSKVKTDPAVAAWGSFKQNTINVNKA
GELQAEAVKLMDRAGYK
>Mature_336_residues
PSARLNRYLTAMICCVTLFTADASGAEDVVVYSARIEQLIKPMFDAFTKDSGVAVKFVTDKEGPLLARLKAEGKNTPADV
LLTTDAGNLWEAAREGLLRPVESEILETNVPAHLRDPLKRWFGLSIRARTIVYNTNKVKPSDLSTYEALADPKWKNRLCI
RTSKKVYNQSLVAMMIAEHGEPKTEQIVKGWITNLATDPLSDDTKAMEYVAAGKCDVTIVNTYYYGRLMKKDPKLPLAIF
WPNQDNSGVHVNISGAGVTKYAHHPQAAIKLIEFLSSEKAQNLFADVNMEYPVNSKVKTDPAVAAWGSFKQNTINVNKAG
ELQAEAVKLMDRAGYK

Specific function: Part Of The Binding-Protein-Dependent Transport System Tbpa-Thipq For Thiamine And Tpp. [C]

COG id: COG1840

COG function: function code P; ABC-type Fe3+ transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 37342; Mature: 37211

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSARLNRYLTAMICCVTLFTADASGAEDVVVYSARIEQLIKPMFDAFTKDSGVAVKFVT
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEE
DKEGPLLARLKAEGKNTPADVLLTTDAGNLWEAAREGLLRPVESEILETNVPAHLRDPLK
CCCCCEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHH
RWFGLSIRARTIVYNTNKVKPSDLSTYEALADPKWKNRLCIRTSKKVYNQSLVAMMIAEH
HHHCCCEEEEEEEEECCCCCCCCCHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHC
GEPKTEQIVKGWITNLATDPLSDDTKAMEYVAAGKCDVTIVNTYYYGRLMKKDPKLPLAI
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEEHCCCCCCCCEEE
FWPNQDNSGVHVNISGAGVTKYAHHPQAAIKLIEFLSSEKAQNLFADVNMEYPVNSKVKT
EECCCCCCCEEEEEECCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DPAVAAWGSFKQNTINVNKAGELQAEAVKLMDRAGYK
CCCHHHCCCCCCCEEECCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PSARLNRYLTAMICCVTLFTADASGAEDVVVYSARIEQLIKPMFDAFTKDSGVAVKFVT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEE
DKEGPLLARLKAEGKNTPADVLLTTDAGNLWEAAREGLLRPVESEILETNVPAHLRDPLK
CCCCCEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHH
RWFGLSIRARTIVYNTNKVKPSDLSTYEALADPKWKNRLCIRTSKKVYNQSLVAMMIAEH
HHHCCCEEEEEEEEECCCCCCCCCHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHC
GEPKTEQIVKGWITNLATDPLSDDTKAMEYVAAGKCDVTIVNTYYYGRLMKKDPKLPLAI
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEEHCCCCCCCCEEE
FWPNQDNSGVHVNISGAGVTKYAHHPQAAIKLIEFLSSEKAQNLFADVNMEYPVNSKVKT
EECCCCCCCEEEEEECCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DPAVAAWGSFKQNTINVNKAGELQAEAVKLMDRAGYK
CCCHHHCCCCCCCEEECCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; thiamine [Periplasm]; H2O [C]

Specific reaction: ATP + thiamine [Periplasm] + H2O = ADP + phosphate + thiamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]