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The map label for this gene is ffh [H]

Identifier: 78779766

GI number: 78779766

Start: 1294618

End: 1296087

Strand: Reverse

Name: ffh [H]

Synonym: PMT9312_1382

Alternate gene names: 78779766

Gene position: 1296087-1294618 (Counterclockwise)

Preceding gene: 78779767

Following gene: 78779765

Centisome position: 75.83

GC content: 35.92

Gene sequence:

>1470_bases
ATGTTTGATGAACTCTCATCACGCTTTGAAGACGCAGTAAAAGGTTTAAGAGGCGAGGCAAAAATTAGTGAAAACAATAT
AAATGATGCCTTGAAGGAAGTTAAACGAGCATTATTAGATGCCGATGTTAGTTTATCTGTAGTAAAAGAGTTTATATCAG
ATGTAAAAGATAAAGCTATTGGAGAAGAAGTGGTTAGGGGTGTAAACCCAGGTCAAAAATTTATAGAAGTTGTTAATAAA
GAATTGATTAATATTATGGGGAATGAAAATTCTCCATTAAATGAAAATCAAAGTAGTCCTACTGTAATTTTAATGGCTGG
ACTTCAGGGAGCTGGTAAAACAACTGCGACAGGAAAATTGGGCCTTTATCTGAAGGAAAAAGATAAAAAAGTTCTTTTGG
TGGCTGCAGATATTTATCGACCAGCAGCTGTAGAGCAACTTAAAACATTGGGCAGTCAATATGATTTAGAAGTTTTTTCG
GCGAAAGAAAAAAATAGCAAACCAGAGGAAATAACAAAGGATGCATTGAATTATGCGAATGAAAATAATTTTAACTCGAT
CATTATTGACACTGCAGGAAGATTGCAAATAGATGATTCAATGATGAGTGAAATGGTTCGGATAAAAGAAGTTTCTAATC
CTGATGAGGTTTTGCTTGTTGTTGATTCTATGATTGGGCAAGAAGCTGCTGACTTGACAAAGTCATTTCATGAAAAAGTA
GGTATTTCAGGAGCGATATTAACAAAGTTGGATGGAGACTCAAGAGGAGGCGCAGCTTTATCAATAAGAAAAATAAGTGG
TAAACCAATTAAATTTATTGGTGTAGGCGAAAAAATAGAGGCACTGCAACCATTCCATCCAGAAAGAATGGCCAGCAGAA
TTTTAGGAATGGGCGATGTATTGACATTAGTAGAAAAAGCCCAAAAAGAAGTTGAGCTTGCTGATGCTGAAGTAATGCAA
AAGAAACTCCAAGAAGCAACTTTTGATTTTAATGATTTTGTTAAGCAAATGAGATTAATTAAAAGGATGGGTTCACTTGG
TGGATTGATAAAGTTAATACCTGGAATGAATAAAATAGACGATGGGATGATAAAAGATGGTGAATATCAACTTAAGAAAA
TAGAATCTATGATCTCCTCTATGACTCTTGAGGAGAAACAAAAACCTGAGGTTCTTGCTGCTCAACCTTCAAGAAGACAA
AGGATCGCTCAGGGTAGTGGATATGAAGCAAAAGATGTAGATAAAGTATTGGCTGATTTTCAAAGAATGAGAGGTTTCAT
GAAACAAATGTCGAATGGAGGAATGCCAGGAATGGGAGGAATGCCAGGAATGGGAGGAATGCCAGGAATGGGAGGAATGC
CAGGAATGGGAGGAATGCCAGGAATGGGAGGAATGTCAGGAATGAGTAGTAACAAACCGATGAAAAAACAAAAAAATAAT
AAAAAGAAAAAAGGGTTTGCTGATTTATAG

Upstream 100 bases:

>100_bases
TGGGTTTTTCTAATAAATCATGGAAGTTGGTTGATTTTGTAAGCGGCCTGTAAATATAAACTTCTAGATCATCTATAATA
ATTAAAATTACTTTTTAATA

Downstream 100 bases:

>100_bases
TTTCTAAATTCTTACCTTTAAATGATATTATTATTAAAAACGTATTAATTTAAGATGATTAAGTTGCGCCTTAAGCGCTT
TGGAAAGAAAAAAGAAGCAA

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MFDELSSRFEDAVKGLRGEAKISENNINDALKEVKRALLDADVSLSVVKEFISDVKDKAIGEEVVRGVNPGQKFIEVVNK
ELINIMGNENSPLNENQSSPTVILMAGLQGAGKTTATGKLGLYLKEKDKKVLLVAADIYRPAAVEQLKTLGSQYDLEVFS
AKEKNSKPEEITKDALNYANENNFNSIIIDTAGRLQIDDSMMSEMVRIKEVSNPDEVLLVVDSMIGQEAADLTKSFHEKV
GISGAILTKLDGDSRGGAALSIRKISGKPIKFIGVGEKIEALQPFHPERMASRILGMGDVLTLVEKAQKEVELADAEVMQ
KKLQEATFDFNDFVKQMRLIKRMGSLGGLIKLIPGMNKIDDGMIKDGEYQLKKIESMISSMTLEEKQKPEVLAAQPSRRQ
RIAQGSGYEAKDVDKVLADFQRMRGFMKQMSNGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGMSGMSSNKPMKKQKNN
KKKKGFADL

Sequences:

>Translated_489_residues
MFDELSSRFEDAVKGLRGEAKISENNINDALKEVKRALLDADVSLSVVKEFISDVKDKAIGEEVVRGVNPGQKFIEVVNK
ELINIMGNENSPLNENQSSPTVILMAGLQGAGKTTATGKLGLYLKEKDKKVLLVAADIYRPAAVEQLKTLGSQYDLEVFS
AKEKNSKPEEITKDALNYANENNFNSIIIDTAGRLQIDDSMMSEMVRIKEVSNPDEVLLVVDSMIGQEAADLTKSFHEKV
GISGAILTKLDGDSRGGAALSIRKISGKPIKFIGVGEKIEALQPFHPERMASRILGMGDVLTLVEKAQKEVELADAEVMQ
KKLQEATFDFNDFVKQMRLIKRMGSLGGLIKLIPGMNKIDDGMIKDGEYQLKKIESMISSMTLEEKQKPEVLAAQPSRRQ
RIAQGSGYEAKDVDKVLADFQRMRGFMKQMSNGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGMSGMSSNKPMKKQKNN
KKKKGFADL
>Mature_489_residues
MFDELSSRFEDAVKGLRGEAKISENNINDALKEVKRALLDADVSLSVVKEFISDVKDKAIGEEVVRGVNPGQKFIEVVNK
ELINIMGNENSPLNENQSSPTVILMAGLQGAGKTTATGKLGLYLKEKDKKVLLVAADIYRPAAVEQLKTLGSQYDLEVFS
AKEKNSKPEEITKDALNYANENNFNSIIIDTAGRLQIDDSMMSEMVRIKEVSNPDEVLLVVDSMIGQEAADLTKSFHEKV
GISGAILTKLDGDSRGGAALSIRKISGKPIKFIGVGEKIEALQPFHPERMASRILGMGDVLTLVEKAQKEVELADAEVMQ
KKLQEATFDFNDFVKQMRLIKRMGSLGGLIKLIPGMNKIDDGMIKDGEYQLKKIESMISSMTLEEKQKPEVLAAQPSRRQ
RIAQGSGYEAKDVDKVLADFQRMRGFMKQMSNGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGMSGMSSNKPMKKQKNN
KKKKGFADL

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=442, Percent_Identity=33.710407239819, Blast_Score=245, Evalue=6e-65,
Organism=Homo sapiens, GI226371618, Length=384, Percent_Identity=33.59375, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI89061728, Length=148, Percent_Identity=40.5405405405405, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI295424842, Length=315, Percent_Identity=24.7619047619048, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI23308697, Length=315, Percent_Identity=24.7619047619048, Blast_Score=110, Evalue=3e-24,
Organism=Escherichia coli, GI1788963, Length=427, Percent_Identity=48.4777517564403, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI1789874, Length=251, Percent_Identity=36.6533864541833, Blast_Score=159, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17539958, Length=432, Percent_Identity=29.1666666666667, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI193206261, Length=300, Percent_Identity=29, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6325345, Length=469, Percent_Identity=31.9829424307036, Blast_Score=246, Evalue=6e-66,
Organism=Saccharomyces cerevisiae, GI6320498, Length=323, Percent_Identity=25.3869969040248, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI17647949, Length=442, Percent_Identity=30.9954751131222, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24641198, Length=303, Percent_Identity=25.7425742574257, Blast_Score=115, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 53253; Mature: 53253

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDELSSRFEDAVKGLRGEAKISENNINDALKEVKRALLDADVSLSVVKEFISDVKDKAI
CCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GEEVVRGVNPGQKFIEVVNKELINIMGNENSPLNENQSSPTVILMAGLQGAGKTTATGKL
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCE
GLYLKEKDKKVLLVAADIYRPAAVEQLKTLGSQYDLEVFSAKEKNSKPEEITKDALNYAN
EEEEECCCCEEEEEEHHHHCHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHCC
ENNFNSIIIDTAGRLQIDDSMMSEMVRIKEVSNPDEVLLVVDSMIGQEAADLTKSFHEKV
CCCCCEEEEECCCCEEECHHHHHHHHHHHHCCCCCCEEEHHHHHHCHHHHHHHHHHHHHH
GISGAILTKLDGDSRGGAALSIRKISGKPIKFIGVGEKIEALQPFHPERMASRILGMGDV
CCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCHHHHHCCCCHHHHHHHHHCCHHH
LTLVEKAQKEVELADAEVMQKKLQEATFDFNDFVKQMRLIKRMGSLGGLIKLIPGMNKID
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
DGMIKDGEYQLKKIESMISSMTLEEKQKPEVLAAQPSRRQRIAQGSGYEAKDVDKVLADF
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHCCCCCCHHHHHHHHHHH
QRMRGFMKQMSNGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGMSGMSSNKPMKKQKNN
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCC
KKKKGFADL
CCCCCCCCC
>Mature Secondary Structure
MFDELSSRFEDAVKGLRGEAKISENNINDALKEVKRALLDADVSLSVVKEFISDVKDKAI
CCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GEEVVRGVNPGQKFIEVVNKELINIMGNENSPLNENQSSPTVILMAGLQGAGKTTATGKL
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCE
GLYLKEKDKKVLLVAADIYRPAAVEQLKTLGSQYDLEVFSAKEKNSKPEEITKDALNYAN
EEEEECCCCEEEEEEHHHHCHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHCC
ENNFNSIIIDTAGRLQIDDSMMSEMVRIKEVSNPDEVLLVVDSMIGQEAADLTKSFHEKV
CCCCCEEEEECCCCEEECHHHHHHHHHHHHCCCCCCEEEHHHHHHCHHHHHHHHHHHHHH
GISGAILTKLDGDSRGGAALSIRKISGKPIKFIGVGEKIEALQPFHPERMASRILGMGDV
CCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCHHHHHCCCCHHHHHHHHHCCHHH
LTLVEKAQKEVELADAEVMQKKLQEATFDFNDFVKQMRLIKRMGSLGGLIKLIPGMNKID
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
DGMIKDGEYQLKKIESMISSMTLEEKQKPEVLAAQPSRRQRIAQGSGYEAKDVDKVLADF
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHCCCCCCHHHHHHHHHHH
QRMRGFMKQMSNGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGMSGMSSNKPMKKQKNN
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCC
KKKKGFADL
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]