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The map label for this gene is uppP

Identifier: 78779227

GI number: 78779227

Start: 779221

End: 780027

Strand: Direct

Name: uppP

Synonym: PMT9312_0843

Alternate gene names: 78779227

Gene position: 779221-780027 (Clockwise)

Preceding gene: 78779226

Following gene: 78779230

Centisome position: 45.59

GC content: 28.87

Gene sequence:

>807_bases
ATGTTTTCGGAATATTTAAAATTTTTTTTATATGGCTTAATACAAGGTTTAACAGAATTTTTCCCAGTAAGTAGTACTGC
TCATTTAAAAGTTATATCTGTGTTTTTTGGGATTGATGATCCAGGCCCTTCTTTGTCTGCGATTATTCAATTGGGAAGTG
TCTTGGCTCTAGTTTGTTACTTTAGGAATGATTTTTTTAAATTAAAAATTCAATCATCAAAAAAAATTTTTGATTATTTA
ATACATGAAAGGTTATTGAGGTCAATCTTTATTGGTACTATCCCAATTATTTTGCTTGGTGGGACAATAAAATTATTTGT
TCCTTATTTTTTTGATGAGATTTTTCGCTCAAATTTATCAATAGCATTAGTTTCTTTCCTAATGGCTATTTTAATGTACA
TAGCTGATAGATCAAAAAAAGGCTCTATAAATTTAAAAAATCATAAGTATTCAGATAGTTTTTTGATAGGTCTTTCTCAA
GCCCTTGCTATTTTTCCAGGTGTTTCAAGATCAGGTGTTACTATTTCTACAGCTCTATTGTCAGGTTGGGGAAGGAGTGA
TTCTGCAAAATTTTCCTTTCTTTTAGGCATGCCGGCTATCTCTTTTGCAGCTATTGTTGAATTCATTTCTTCTTTTAATG
CATTTTCTTCATTTAGTTTTTTTCCTCTAATTGTTGGTCTTACAACGACATTTTTGTCTTCATTATTAGCTATCCATTTC
TTATTAAAGTATTTCTCTTCAAATGGTTTGAAATTATTTATTATCTATCGCATTGTATTTGGTTTTGTAATACTTTTGAA
TTTATAG

Upstream 100 bases:

>100_bases
CTCAAATCTACAATTCCATTTGCTCTCAAATTCTAAATAAATTTATATTTTAGTTTTTACTTGTTTAATCTAAATTGCTT
GTAATTAATTATTTGTTTAT

Downstream 100 bases:

>100_bases
TTCGTTGTAAAAAAAAATCCAATTATGTTAATGTTTAAAATAAATTTTGACTAATGAATATTCTTATATCATTCCAACTG
GGTGAAGTTGAAGTTTCAAA

Product: undecaprenyl-diphosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MFSEYLKFFLYGLIQGLTEFFPVSSTAHLKVISVFFGIDDPGPSLSAIIQLGSVLALVCYFRNDFFKLKIQSSKKIFDYL
IHERLLRSIFIGTIPIILLGGTIKLFVPYFFDEIFRSNLSIALVSFLMAILMYIADRSKKGSINLKNHKYSDSFLIGLSQ
ALAIFPGVSRSGVTISTALLSGWGRSDSAKFSFLLGMPAISFAAIVEFISSFNAFSSFSFFPLIVGLTTTFLSSLLAIHF
LLKYFSSNGLKLFIIYRIVFGFVILLNL

Sequences:

>Translated_268_residues
MFSEYLKFFLYGLIQGLTEFFPVSSTAHLKVISVFFGIDDPGPSLSAIIQLGSVLALVCYFRNDFFKLKIQSSKKIFDYL
IHERLLRSIFIGTIPIILLGGTIKLFVPYFFDEIFRSNLSIALVSFLMAILMYIADRSKKGSINLKNHKYSDSFLIGLSQ
ALAIFPGVSRSGVTISTALLSGWGRSDSAKFSFLLGMPAISFAAIVEFISSFNAFSSFSFFPLIVGLTTTFLSSLLAIHF
LLKYFSSNGLKLFIIYRIVFGFVILLNL
>Mature_268_residues
MFSEYLKFFLYGLIQGLTEFFPVSSTAHLKVISVFFGIDDPGPSLSAIIQLGSVLALVCYFRNDFFKLKIQSSKKIFDYL
IHERLLRSIFIGTIPIILLGGTIKLFVPYFFDEIFRSNLSIALVSFLMAILMYIADRSKKGSINLKNHKYSDSFLIGLSQ
ALAIFPGVSRSGVTISTALLSGWGRSDSAKFSFLLGMPAISFAAIVEFISSFNAFSSFSFFPLIVGLTTTFLSSLLAIHF
LLKYFSSNGLKLFIIYRIVFGFVILLNL

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=259, Percent_Identity=32.4324324324324, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_PROM9 (Q31B42)

Other databases:

- EMBL:   CP000111
- RefSeq:   YP_397339.1
- STRING:   Q31B42
- GeneID:   3765643
- GenomeReviews:   CP000111_GR
- KEGG:   pmi:PMT9312_0843
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   RSAMTIV
- ProtClustDB:   CLSK922039
- BioCyc:   PMAR74546:PMT9312_0843-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29926; Mature: 29926

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11284194)-; HASH(0x123495ec)-; HASH(0xff3f0b4)-; HASH(0x102a40f0)-; HASH(0x123471c4)-; HASH(0xfdd7b70)-; HASH(0xff3ee14)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSEYLKFFLYGLIQGLTEFFPVSSTAHLKVISVFFGIDDPGPSLSAIIQLGSVLALVCY
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHH
FRNDFFKLKIQSSKKIFDYLIHERLLRSIFIGTIPIILLGGTIKLFVPYFFDEIFRSNLS
HHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHH
IALVSFLMAILMYIADRSKKGSINLKNHKYSDSFLIGLSQALAIFPGVSRSGVTISTALL
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHH
SGWGRSDSAKFSFLLGMPAISFAAIVEFISSFNAFSSFSFFPLIVGLTTTFLSSLLAIHF
HCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LLKYFSSNGLKLFIIYRIVFGFVILLNL
HHHHHHCCCCEEHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MFSEYLKFFLYGLIQGLTEFFPVSSTAHLKVISVFFGIDDPGPSLSAIIQLGSVLALVCY
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHH
FRNDFFKLKIQSSKKIFDYLIHERLLRSIFIGTIPIILLGGTIKLFVPYFFDEIFRSNLS
HHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHH
IALVSFLMAILMYIADRSKKGSINLKNHKYSDSFLIGLSQALAIFPGVSRSGVTISTALL
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHH
SGWGRSDSAKFSFLLGMPAISFAAIVEFISSFNAFSSFSFFPLIVGLTTTFLSSLLAIHF
HCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LLKYFSSNGLKLFIIYRIVFGFVILLNL
HHHHHHCCCCEEHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA