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The map label for this gene is purQ

Identifier: 78779172

GI number: 78779172

Start: 734385

End: 735050

Strand: Direct

Name: purQ

Synonym: PMT9312_0788

Alternate gene names: 78779172

Gene position: 734385-735050 (Clockwise)

Preceding gene: 78779171

Following gene: 78779189

Centisome position: 42.97

GC content: 35.14

Gene sequence:

>666_bases
ATGGATAATTTTACTGTAGGAGTTGTTGTCTTCCCTGGTTCTAATTGTGATCGTGATGTTTCATGGGCATTGGAAGGTTG
TTTAGACATAAGAACAAAATACTTGTGGCATGAGTCTTCAGATTTAAGTGATGTAGATGCAATAGTTTTACCTGGAGGAT
TTAGCTATGGTGATTATTTAAGATGTGGAGCAATTGCGAGATTCTCTCCATTAATAAATGCCTTGGATGAGTTTGTTAAA
AGCGGGAAAAGAGTTTTAGGAATTTGTAATGGGTTTCAAATTTTGACAGAATCAGGGTTTTTGCCTGGTGCTCTTGTTGC
AAATAAAAATCTTAATTTTATCTGTGATGACGTTGAACTGGATATCGTTTCTACAAAAGGAGGTTGGTTTAATAATGGAG
ATGAAAAACAAACTATTAAGTTGCCAATTGCTCATGGGGAAGGAAGATATCATTGTGATTCTGATACTTTAAAAAAACTT
GTAGATAATGAATTGATCGCTTTGAGATATAAAAACAACCCCAATGGATCCTCATTCGATATCGCAGGCATAACTAATGA
AAAGGGAAATGTTCTAGGTTTAATGCCTCATCCAGAGCGAGCATGTGACGAGACAATTGGTGGGACTGATGGTCTCTTTA
CATTAAAATCATTAATATTGAAATAA

Upstream 100 bases:

>100_bases
GGTGAAAACGAAGTAAGAGAAAAAATTGATTTATTGTGTGATAGGTTATTCGCAAATACTGTTATTGAAGATTATGAGTA
TTCACTAGAAAAATTATAAG

Downstream 100 bases:

>100_bases
AAAAAAGACCCCCAATTTTGGAGGCCTTTTTTTTTAATTTGAGAAGAAATTAAACAGTAGCTTTTACTTTTGGATCTAAA
TCACCTTTTGCGTAAAGATC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MDNFTVGVVVFPGSNCDRDVSWALEGCLDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYLRCGAIARFSPLINALDEFVK
SGKRVLGICNGFQILTESGFLPGALVANKNLNFICDDVELDIVSTKGGWFNNGDEKQTIKLPIAHGEGRYHCDSDTLKKL
VDNELIALRYKNNPNGSSFDIAGITNEKGNVLGLMPHPERACDETIGGTDGLFTLKSLILK

Sequences:

>Translated_221_residues
MDNFTVGVVVFPGSNCDRDVSWALEGCLDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYLRCGAIARFSPLINALDEFVK
SGKRVLGICNGFQILTESGFLPGALVANKNLNFICDDVELDIVSTKGGWFNNGDEKQTIKLPIAHGEGRYHCDSDTLKKL
VDNELIALRYKNNPNGSSFDIAGITNEKGNVLGLMPHPERACDETIGGTDGLFTLKSLILK
>Mature_221_residues
MDNFTVGVVVFPGSNCDRDVSWALEGCLDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYLRCGAIARFSPLINALDEFVK
SGKRVLGICNGFQILTESGFLPGALVANKNLNFICDDVELDIVSTKGGWFNNGDEKQTIKLPIAHGEGRYHCDSDTLKKL
VDNELIALRYKNNPNGSSFDIAGITNEKGNVLGLMPHPERACDETIGGTDGLFTLKSLILK

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=196, Percent_Identity=32.6530612244898, Blast_Score=78, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321498, Length=237, Percent_Identity=26.5822784810127, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582111, Length=232, Percent_Identity=29.7413793103448, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582109, Length=232, Percent_Identity=29.7413793103448, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17137292, Length=232, Percent_Identity=29.7413793103448, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_PROM9 (Q31B97)

Other databases:

- EMBL:   CP000111
- RefSeq:   YP_397284.1
- ProteinModelPortal:   Q31B97
- SMR:   Q31B97
- STRING:   Q31B97
- GeneID:   3765588
- GenomeReviews:   CP000111_GR
- KEGG:   pmi:PMT9312_0788
- eggNOG:   COG0047
- HOGENOM:   HBG302712
- OMA:   HPENHVE
- ProtClustDB:   PRK03619
- BioCyc:   PMAR74546:PMT9312_0788-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF07685 GATase_3

EC number: =6.3.5.3

Molecular weight: Translated: 24108; Mature: 24108

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS51273 GATASE_TYPE_1

Important sites: ACT_SITE 89-89 ACT_SITE 197-197 ACT_SITE 199-199

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNFTVGVVVFPGSNCDRDVSWALEGCLDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYL
CCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCEEEECCCCCCCCHH
RCGAIARFSPLINALDEFVKSGKRVLGICNGFQILTESGFLPGALVANKNLNFICDDVEL
HHCHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCCCCEEEECCCCCEEECCEEE
DIVSTKGGWFNNGDEKQTIKLPIAHGEGRYHCDSDTLKKLVDNELIALRYKNNPNGSSFD
EEEECCCCCCCCCCCCEEEEEEEECCCCCEEECHHHHHHHHCCCEEEEEECCCCCCCEEE
IAGITNEKGNVLGLMPHPERACDETIGGTDGLFTLKSLILK
EEEEECCCCCEEEECCCCHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MDNFTVGVVVFPGSNCDRDVSWALEGCLDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYL
CCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCEEEECCCCCCCCHH
RCGAIARFSPLINALDEFVKSGKRVLGICNGFQILTESGFLPGALVANKNLNFICDDVEL
HHCHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCCCCEEEECCCCCEEECCEEE
DIVSTKGGWFNNGDEKQTIKLPIAHGEGRYHCDSDTLKKLVDNELIALRYKNNPNGSSFD
EEEECCCCCCCCCCCCEEEEEEEECCCCCEEECHHHHHHHHCCCEEEEEECCCCCCCEEE
IAGITNEKGNVLGLMPHPERACDETIGGTDGLFTLKSLILK
EEEEECCCCCEEEECCCCHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA