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The map label for this gene is hemA

Identifier: 78779160

GI number: 78779160

Start: 723585

End: 724895

Strand: Direct

Name: hemA

Synonym: PMT9312_0776

Alternate gene names: 78779160

Gene position: 723585-724895 (Clockwise)

Preceding gene: 78779159

Following gene: 78779161

Centisome position: 42.33

GC content: 32.57

Gene sequence:

>1311_bases
ATGCATATTGTTGTCGTCGGACTAAGTCATCGCACGGCACCTGTCGAAGTGCGTGAGAAGTTAAGTATTCCTGACCAATC
CATAACAAAATCATTGAAAGCATTAAAGGCTTTCTCTGAGGTATTAGAGGTGTCAATTTTAAGTACTTGTAATAGGCTAG
AAATATATGCCCTGGTAAAGGATAAAAATACTGGAATTTCATCTATTAAAGAATTTATATCAGATTATTCCGGAATTATT
TTTGAAGATTTAAATCCACATCTTTTTTGCTTTAGACAAGAAGATGCGGTTTTGCATTTGATGAAAGTTTCGGCAGGACT
TGATAGCCTCGTATTAGGAGAAGGACAAATCCTTTCGCAGGTAAAAAAAATGATGAGATTAGGTCAAGAGAATCAATCTA
CTGGGCCTATTCTTAATAGATTATTAACTCAATCAGTTAGTACAGGTAAAAAAGTTAGATCCGAAACAAATTTAGGAACT
GGAGCTGTATCAATAAGTTCAGCTGCGGTAGAACTTGCTCAATTAAAAATTGGACAAGAAAAGGGGTTTGATACTCTTGT
AAGTTTGGAATCAGAAAAGGTTCTTGTAGTTGGAGCTGGTCGGATGAGTAGACTTTTAATAACTCATTTAAAAGCAAAAG
GATGTCATAAACTGATTCTTGTCAATAGAAATATTGATAGAGCATTAAATCTTGCTATAGATTTCCCCGATATAGAGATT
GTTTGTAAAGGGTTAAACGAATTAGATGAAAATATATCAATATCTTCTCTTGTTTTCACAAGTACAGCTTCCGAAGAGCC
AATAATTGATCTCGCTAAAATTGAAAAATTAAATTTGAATAATAAACTTAAATTTATTGATATTGGTGTGCCGAGAAATA
TTTCTAATGATGTTAAAAATCATCAATTTGTAAAATCATTTGATGTAGATGATTTACAAGAGGTCGTTTCAAGAAATCAA
GAATTTAGACAGAAAATTGCAAAGGAAGCAGAATCTTTAGTAGAAGAAGAAAGAATTATTTTTCTAGAATGGTGGGCAAG
TCTAGAAGCGGTTCCAGTAATTAATAAACTTAGATCAGATTTGGAGTTAATTAGAAAAGAGGAATTGCAAAAAGCACTTA
GTAGGATGGGACCAGATTTTTCTGCCCGAGAAAGAAAAGTTGTAGAAGCTCTTACTAAAGGAATTATCAATAAAATACTT
CATACACCTGTTACCAAATTGAGAAGTCCTCAATCAAGAGAAGAAAGACAAGCTTCTTTGAAAATTGTTGAAAAGTTGTT
TTCTTTGGTAGATGAAGATAAAAATAGCTAA

Upstream 100 bases:

>100_bases
AGTAATTAGCACATTAGATAGTACTGCAAGATTCACAAATACTGTCCATATAAAAGATGGTGCAAAGAGTATCAGCCTTT
AAAAATTCACTTTTGATTTT

Downstream 100 bases:

>100_bases
ATTTTACTTATTTATATTAAGTTTTTCTAGTAATTTATCGAAATACCTTTGTAAACTGACCATTACTATTTCAAATTTAG
CCCATAATCAGTTACTTTAA

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MHIVVVGLSHRTAPVEVREKLSIPDQSITKSLKALKAFSEVLEVSILSTCNRLEIYALVKDKNTGISSIKEFISDYSGII
FEDLNPHLFCFRQEDAVLHLMKVSAGLDSLVLGEGQILSQVKKMMRLGQENQSTGPILNRLLTQSVSTGKKVRSETNLGT
GAVSISSAAVELAQLKIGQEKGFDTLVSLESEKVLVVGAGRMSRLLITHLKAKGCHKLILVNRNIDRALNLAIDFPDIEI
VCKGLNELDENISISSLVFTSTASEEPIIDLAKIEKLNLNNKLKFIDIGVPRNISNDVKNHQFVKSFDVDDLQEVVSRNQ
EFRQKIAKEAESLVEEERIIFLEWWASLEAVPVINKLRSDLELIRKEELQKALSRMGPDFSARERKVVEALTKGIINKIL
HTPVTKLRSPQSREERQASLKIVEKLFSLVDEDKNS

Sequences:

>Translated_436_residues
MHIVVVGLSHRTAPVEVREKLSIPDQSITKSLKALKAFSEVLEVSILSTCNRLEIYALVKDKNTGISSIKEFISDYSGII
FEDLNPHLFCFRQEDAVLHLMKVSAGLDSLVLGEGQILSQVKKMMRLGQENQSTGPILNRLLTQSVSTGKKVRSETNLGT
GAVSISSAAVELAQLKIGQEKGFDTLVSLESEKVLVVGAGRMSRLLITHLKAKGCHKLILVNRNIDRALNLAIDFPDIEI
VCKGLNELDENISISSLVFTSTASEEPIIDLAKIEKLNLNNKLKFIDIGVPRNISNDVKNHQFVKSFDVDDLQEVVSRNQ
EFRQKIAKEAESLVEEERIIFLEWWASLEAVPVINKLRSDLELIRKEELQKALSRMGPDFSARERKVVEALTKGIINKIL
HTPVTKLRSPQSREERQASLKIVEKLFSLVDEDKNS
>Mature_436_residues
MHIVVVGLSHRTAPVEVREKLSIPDQSITKSLKALKAFSEVLEVSILSTCNRLEIYALVKDKNTGISSIKEFISDYSGII
FEDLNPHLFCFRQEDAVLHLMKVSAGLDSLVLGEGQILSQVKKMMRLGQENQSTGPILNRLLTQSVSTGKKVRSETNLGT
GAVSISSAAVELAQLKIGQEKGFDTLVSLESEKVLVVGAGRMSRLLITHLKAKGCHKLILVNRNIDRALNLAIDFPDIEI
VCKGLNELDENISISSLVFTSTASEEPIIDLAKIEKLNLNNKLKFIDIGVPRNISNDVKNHQFVKSFDVDDLQEVVSRNQ
EFRQKIAKEAESLVEEERIIFLEWWASLEAVPVINKLRSDLELIRKEELQKALSRMGPDFSARERKVVEALTKGIINKIL
HTPVTKLRSPQSREERQASLKIVEKLFSLVDEDKNS

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=413, Percent_Identity=34.8668280871671, Blast_Score=214, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 48724; Mature: 48724

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIVVVGLSHRTAPVEVREKLSIPDQSITKSLKALKAFSEVLEVSILSTCNRLEIYALVK
CEEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
DKNTGISSIKEFISDYSGIIFEDLNPHLFCFRQEDAVLHLMKVSAGLDSLVLGEGQILSQ
CCCCCHHHHHHHHHHCCCEEEECCCCCEEEEECCCHHHHHHHHHCCCCCEEECCCHHHHH
VKKMMRLGQENQSTGPILNRLLTQSVSTGKKVRSETNLGTGAVSISSAAVELAQLKIGQE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCC
KGFDTLVSLESEKVLVVGAGRMSRLLITHLKAKGCHKLILVNRNIDRALNLAIDFPDIEI
CCCHHHEECCCCCEEEEECCHHHHHHHHHHHCCCCEEEEEEECCCCHHEEEEEECCCHHH
VCKGLNELDENISISSLVFTSTASEEPIIDLAKIEKLNLNNKLKFIDIGVPRNISNDVKN
HHHHHHHHHCCCCCHHEEEECCCCCCCCHHHHHHHEECCCCCEEEEEECCCCCCHHHHHH
HQFVKSFDVDDLQEVVSRNQEFRQKIAKEAESLVEEERIIFLEWWASLEAVPVINKLRSD
HHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEEHHCCCHHHHHHHHHHH
LELIRKEELQKALSRMGPDFSARERKVVEALTKGIINKILHTPVTKLRSPQSREERQASL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHH
KIVEKLFSLVDEDKNS
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MHIVVVGLSHRTAPVEVREKLSIPDQSITKSLKALKAFSEVLEVSILSTCNRLEIYALVK
CEEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
DKNTGISSIKEFISDYSGIIFEDLNPHLFCFRQEDAVLHLMKVSAGLDSLVLGEGQILSQ
CCCCCHHHHHHHHHHCCCEEEECCCCCEEEEECCCHHHHHHHHHCCCCCEEECCCHHHHH
VKKMMRLGQENQSTGPILNRLLTQSVSTGKKVRSETNLGTGAVSISSAAVELAQLKIGQE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCC
KGFDTLVSLESEKVLVVGAGRMSRLLITHLKAKGCHKLILVNRNIDRALNLAIDFPDIEI
CCCHHHEECCCCCEEEEECCHHHHHHHHHHHCCCCEEEEEEECCCCHHEEEEEECCCHHH
VCKGLNELDENISISSLVFTSTASEEPIIDLAKIEKLNLNNKLKFIDIGVPRNISNDVKN
HHHHHHHHHCCCCCHHEEEECCCCCCCCHHHHHHHEECCCCCEEEEEECCCCCCHHHHHH
HQFVKSFDVDDLQEVVSRNQEFRQKIAKEAESLVEEERIIFLEWWASLEAVPVINKLRSD
HHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEEHHCCCHHHHHHHHHHH
LELIRKEELQKALSRMGPDFSARERKVVEALTKGIINKILHTPVTKLRSPQSREERQASL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHH
KIVEKLFSLVDEDKNS
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA