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The map label for this gene is csgA [H]

Identifier: 78779089

GI number: 78779089

Start: 658581

End: 659246

Strand: Direct

Name: csgA [H]

Synonym: PMT9312_0705

Alternate gene names: 78779089

Gene position: 658581-659246 (Clockwise)

Preceding gene: 78779082

Following gene: 78779094

Centisome position: 38.53

GC content: 32.13

Gene sequence:

>666_bases
ATGTCAACTTATCTAATCACAGGATCAAATAGGGGTATTGGATTAGAATTGTGTAGGCAAATTCATAAGAGAGGAGATAT
TGTAATTGCAACGTGTAGGAAAGCTTCAAAAGAACTTAGGGATTTAGGAGTGAGAATTGAAGAGAATATAGAAATTTCTT
CTGATGAGTCAATAACAAATTTGTGTAAAAAACTATCCGGAGTTAATTTAGATTGCTTAATTCATAATGCAGGAATTTAT
GAATTTAATTCTTTCGAAAACTTAGATAAAGAAAGTATTTTGCGTCAATTTGAAGTGAATGCATTAAGCCCAATATTTCT
TACTCAATCACTCAAACATCTTTTAAAAAGATCCTCTAAAGTTGCTTTTATTACAAGTAGAATGGGATCTATCGAAGATA
ATTCATCTGGAAGTTCTTATGGTTACAGGATGTCTAAAGTCGCCTTATCAATGGCAGCAAAATCAATTTCTATAGATTTA
TCAAAAGAAGATATTTTTGTAGCTATTTTACATCCAGGGCTCGTGAGTACAAGAATGACAGGCTTTACTAGAAATGGAAT
TAGTCCTGAAGAATCAGCAAATGGCCTTTTAAAACGAATTGATTCTTTAAATAAAAAAAACTCAGGTACGTTTTGGCATG
CCAACGGAGAAGTTTTGCCTTGGTAA

Upstream 100 bases:

>100_bases
ACCTTAAAAAAATCTTATCAGGATTTTATACCTTTTATCTTTTTCTAGTTTGTTTTTTTTGATATTTGGTTTAGATTAAT
TTTTTATTTTTAGTTTAAAG

Downstream 100 bases:

>100_bases
TATCTAAACTTTTATATTGAAGAGATTTATATCGTTAATTTGTTAAAAAACTTTTAAATTTTCAACCAATTTCGTTGCTT
GTTTAATTCTTTTAGTTATC

Product: short-chain dehydrogenase/reductase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSTYLITGSNRGIGLELCRQIHKRGDIVIATCRKASKELRDLGVRIEENIEISSDESITNLCKKLSGVNLDCLIHNAGIY
EFNSFENLDKESILRQFEVNALSPIFLTQSLKHLLKRSSKVAFITSRMGSIEDNSSGSSYGYRMSKVALSMAAKSISIDL
SKEDIFVAILHPGLVSTRMTGFTRNGISPEESANGLLKRIDSLNKKNSGTFWHANGEVLPW

Sequences:

>Translated_221_residues
MSTYLITGSNRGIGLELCRQIHKRGDIVIATCRKASKELRDLGVRIEENIEISSDESITNLCKKLSGVNLDCLIHNAGIY
EFNSFENLDKESILRQFEVNALSPIFLTQSLKHLLKRSSKVAFITSRMGSIEDNSSGSSYGYRMSKVALSMAAKSISIDL
SKEDIFVAILHPGLVSTRMTGFTRNGISPEESANGLLKRIDSLNKKNSGTFWHANGEVLPW
>Mature_220_residues
STYLITGSNRGIGLELCRQIHKRGDIVIATCRKASKELRDLGVRIEENIEISSDESITNLCKKLSGVNLDCLIHNAGIYE
FNSFENLDKESILRQFEVNALSPIFLTQSLKHLLKRSSKVAFITSRMGSIEDNSSGSSYGYRMSKVALSMAAKSISIDLS
KEDIFVAILHPGLVSTRMTGFTRNGISPEESANGLLKRIDSLNKKNSGTFWHANGEVLPW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Escherichia coli, GI1786701, Length=185, Percent_Identity=27.027027027027, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17558996, Length=248, Percent_Identity=30.6451612903226, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17559964, Length=248, Percent_Identity=35.8870967741936, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17559962, Length=247, Percent_Identity=35.6275303643725, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI72001658, Length=244, Percent_Identity=34.8360655737705, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17558994, Length=242, Percent_Identity=33.0578512396694, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI193207563, Length=242, Percent_Identity=30.5785123966942, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17542178, Length=239, Percent_Identity=32.2175732217573, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17558992, Length=244, Percent_Identity=32.7868852459016, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17558990, Length=247, Percent_Identity=28.7449392712551, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17541382, Length=251, Percent_Identity=30.6772908366534, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17532177, Length=238, Percent_Identity=31.9327731092437, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17558006, Length=212, Percent_Identity=31.1320754716981, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322779, Length=245, Percent_Identity=30.6122448979592, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24640547, Length=249, Percent_Identity=30.9236947791165, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24643142, Length=180, Percent_Identity=30.5555555555556, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24486; Mature: 24355

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTYLITGSNRGIGLELCRQIHKRGDIVIATCRKASKELRDLGVRIEENIEISSDESITN
CCEEEEECCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHCCCEEECCEEECCCHHHHH
LCKKLSGVNLDCLIHNAGIYEFNSFENLDKESILRQFEVNALSPIFLTQSLKHLLKRSSK
HHHHHCCCCEEEEEECCCCEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
VAFITSRMGSIEDNSSGSSYGYRMSKVALSMAAKSISIDLSKEDIFVAILHPGLVSTRMT
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCHHHHHHC
GFTRNGISPEESANGLLKRIDSLNKKNSGTFWHANGEVLPW
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
STYLITGSNRGIGLELCRQIHKRGDIVIATCRKASKELRDLGVRIEENIEISSDESITN
CEEEEECCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHCCCEEECCEEECCCHHHHH
LCKKLSGVNLDCLIHNAGIYEFNSFENLDKESILRQFEVNALSPIFLTQSLKHLLKRSSK
HHHHHCCCCEEEEEECCCCEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
VAFITSRMGSIEDNSSGSSYGYRMSKVALSMAAKSISIDLSKEDIFVAILHPGLVSTRMT
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCHHHHHHC
GFTRNGISPEESANGLLKRIDSLNKKNSGTFWHANGEVLPW
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]