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The map label for this gene is fur [H]

Identifier: 78779022

GI number: 78779022

Start: 600466

End: 600918

Strand: Direct

Name: fur [H]

Synonym: PMT9312_0637

Alternate gene names: 78779022

Gene position: 600466-600918 (Clockwise)

Preceding gene: 78779019

Following gene: 78779025

Centisome position: 35.13

GC content: 34.88

Gene sequence:

>453_bases
TTGTCATTATCCTCGCAATACAATGTCATTACATCTCCTCTCGGCGATGGTTTACATAAAGAGGGGAAGAGGTTAACTCC
TCAGAGGCTAAAGGTTCTTAATTTATTTGAAAATATTGGCTCTGGAAAGCATCTTAGTGCTGAAGAGGTTCATGAAAAGT
TAGTTAAAACAAGCTCCAAAGTTTCACTAGCAACAATTTATAGAACTTTAAGACTTTTAGTACAAATGGGTTTGCTTCAT
GAATTAGAACTCAGTGAGGGTGGACACAGATATGAATTGCTTAGTAATGACACACCGGATCATCATCATTTGATTTGTAT
TAGGTGTGGAAGAACAGAAGAATTCGAAAATGACGAAGTTTTAGAAGCAGGCAAAGATGCAGCAAAAGTTAATGGTTTTA
AACTAATTGAATCATCTTTAAATGTAAGAGCTATTTGTCCTAATTGTATTTAG

Upstream 100 bases:

>100_bases
TTTAACATAATATTTTGAAGAACTTTAGTAAACATTTTAAATCAAAAAGTTGTTTTACTCTCATCTAGAGTTATTATTGA
GAATAGCCATGAGTTAATAA

Downstream 100 bases:

>100_bases
TGGGTTTTAACTTAAAGTCCCTCCACAACTTGACCCTGCACCTGCAGTGCAAGCAAAACAATGTTCTTTTACAGCTACCC
GGTAGTCAAAAGTAAATGAT

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MSLSSQYNVITSPLGDGLHKEGKRLTPQRLKVLNLFENIGSGKHLSAEEVHEKLVKTSSKVSLATIYRTLRLLVQMGLLH
ELELSEGGHRYELLSNDTPDHHHLICIRCGRTEEFENDEVLEAGKDAAKVNGFKLIESSLNVRAICPNCI

Sequences:

>Translated_150_residues
MSLSSQYNVITSPLGDGLHKEGKRLTPQRLKVLNLFENIGSGKHLSAEEVHEKLVKTSSKVSLATIYRTLRLLVQMGLLH
ELELSEGGHRYELLSNDTPDHHHLICIRCGRTEEFENDEVLEAGKDAAKVNGFKLIESSLNVRAICPNCI
>Mature_149_residues
SLSSQYNVITSPLGDGLHKEGKRLTPQRLKVLNLFENIGSGKHLSAEEVHEKLVKTSSKVSLATIYRTLRLLVQMGLLHE
LELSEGGHRYELLSNDTPDHHHLICIRCGRTEEFENDEVLEAGKDAAKVNGFKLIESSLNVRAICPNCI

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates genes involved in iron scavenging or photosynthetic electron transport [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=133, Percent_Identity=30.8270676691729, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16744; Mature: 16613

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSSQYNVITSPLGDGLHKEGKRLTPQRLKVLNLFENIGSGKHLSAEEVHEKLVKTSSK
CCCCCCCCEEECCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
VSLATIYRTLRLLVQMGLLHELELSEGGHRYELLSNDTPDHHHLICIRCGRTEEFENDEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCHH
LEAGKDAAKVNGFKLIESSLNVRAICPNCI
HHCCCCHHHCCCHHHHHCCCCEEEECCCCC
>Mature Secondary Structure 
SLSSQYNVITSPLGDGLHKEGKRLTPQRLKVLNLFENIGSGKHLSAEEVHEKLVKTSSK
CCCCCCCEEECCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
VSLATIYRTLRLLVQMGLLHELELSEGGHRYELLSNDTPDHHHLICIRCGRTEEFENDEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCHH
LEAGKDAAKVNGFKLIESSLNVRAICPNCI
HHCCCCHHHCCCHHHHHCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704986 [H]