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The map label for this gene is trpF [H]

Identifier: 78778922

GI number: 78778922

Start: 502728

End: 503384

Strand: Reverse

Name: trpF [H]

Synonym: PMT9312_0537

Alternate gene names: 78778922

Gene position: 503384-502728 (Counterclockwise)

Preceding gene: 78778924

Following gene: 78778915

Centisome position: 29.45

GC content: 33.03

Gene sequence:

>657_bases
ATGCCCAAGACTAACACTTTAGTTAAAATTTGCGGACTCACGTCTGAAGAACAAGCTCTTCAAGTCGCCAAATTAGGAGC
TCATGCTATCGGAATTATTGCGGTTGAAGAGTCACCAAGGTATGTATCAGCTGTAAAAAAGAAGAAAATTTTTAAAACAT
TAGAAAGTTTTTACCCAAAAATCGAGAGGGTATCTGTTGTCCAAAATTGTTCTATAGATTTAATTATTAAAAATTTCTTA
GGAAACCCTAGTGAAACTATAATTCAATTACATGGAGATGAGGATATTGATTACTGCAAAAGGTTAAGGGAAAAAATTCC
AAATATTGGAATATGGAAGGCCTTCAGAATAAAAACTAAAAAGGACTTGGATCAAATAAAACCTTTTGAAGATTTTGTAG
ATGCGATACTACTTGATTCATGGAATAAAGAAACTTATGGGGGTTCAGGGAAAAAAATAAAAACTATTTATCTAGAGAAT
CTCCAATTTAGTAAACCTTGGTGGCTAGCAGGCGGAATATCAACTGAATGGATTGATGAAATTTTAACTGACATCAAACC
AGATGGACTAGACATTTCAAGCAGTATTGAAATATCTCCAGGCTTGAAAGATCTAGAAAAAACAGGGGCCCTAATTAAGT
TTTTAAAAAAGAATTAG

Upstream 100 bases:

>100_bases
TCTGAAGGGAATTCCCCATATTTTAAAAATTTGCCAACTTCTCAAAAATAATCTCCGCTATATTTAGCAATAATATTAAT
TTTACATACTGGATAACGAT

Downstream 100 bases:

>100_bases
TAGTTATTAGTTGCAGATTGCTGTTTTACAAGTTCAAAAAATTCTTGTTTTAAACTTAAGTCATGCCTAAAGTCGCCTCT
TACTACAGAATTAATCATAC

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MPKTNTLVKICGLTSEEQALQVAKLGAHAIGIIAVEESPRYVSAVKKKKIFKTLESFYPKIERVSVVQNCSIDLIIKNFL
GNPSETIIQLHGDEDIDYCKRLREKIPNIGIWKAFRIKTKKDLDQIKPFEDFVDAILLDSWNKETYGGSGKKIKTIYLEN
LQFSKPWWLAGGISTEWIDEILTDIKPDGLDISSSIEISPGLKDLEKTGALIKFLKKN

Sequences:

>Translated_218_residues
MPKTNTLVKICGLTSEEQALQVAKLGAHAIGIIAVEESPRYVSAVKKKKIFKTLESFYPKIERVSVVQNCSIDLIIKNFL
GNPSETIIQLHGDEDIDYCKRLREKIPNIGIWKAFRIKTKKDLDQIKPFEDFVDAILLDSWNKETYGGSGKKIKTIYLEN
LQFSKPWWLAGGISTEWIDEILTDIKPDGLDISSSIEISPGLKDLEKTGALIKFLKKN
>Mature_217_residues
PKTNTLVKICGLTSEEQALQVAKLGAHAIGIIAVEESPRYVSAVKKKKIFKTLESFYPKIERVSVVQNCSIDLIIKNFLG
NPSETIIQLHGDEDIDYCKRLREKIPNIGIWKAFRIKTKKDLDQIKPFEDFVDAILLDSWNKETYGGSGKKIKTIYLENL
QFSKPWWLAGGISTEWIDEILTDIKPDGLDISSSIEISPGLKDLEKTGALIKFLKKN

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=212, Percent_Identity=30.188679245283, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 24625; Mature: 24494

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTNTLVKICGLTSEEQALQVAKLGAHAIGIIAVEESPRYVSAVKKKKIFKTLESFYPK
CCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCH
IERVSVVQNCSIDLIIKNFLGNPSETIIQLHGDEDIDYCKRLREKIPNIGIWKAFRIKTK
HHHHHHHHCCCHHHHHHHHCCCCCHHEEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCH
KDLDQIKPFEDFVDAILLDSWNKETYGGSGKKIKTIYLENLQFSKPWWLAGGISTEWIDE
HHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEECCCCHHHHHH
ILTDIKPDGLDISSSIEISPGLKDLEKTGALIKFLKKN
HHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PKTNTLVKICGLTSEEQALQVAKLGAHAIGIIAVEESPRYVSAVKKKKIFKTLESFYPK
CCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCH
IERVSVVQNCSIDLIIKNFLGNPSETIIQLHGDEDIDYCKRLREKIPNIGIWKAFRIKTK
HHHHHHHHCCCHHHHHHHHCCCCCHHEEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCH
KDLDQIKPFEDFVDAILLDSWNKETYGGSGKKIKTIYLENLQFSKPWWLAGGISTEWIDE
HHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEECCCCHHHHHH
ILTDIKPDGLDISSSIEISPGLKDLEKTGALIKFLKKN
HHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA