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The map label for this gene is 78778610

Identifier: 78778610

GI number: 78778610

Start: 216248

End: 217153

Strand: Direct

Name: 78778610

Synonym: PMT9312_0224

Alternate gene names: NA

Gene position: 216248-217153 (Clockwise)

Preceding gene: 78778607

Following gene: 78778611

Centisome position: 12.65

GC content: 31.02

Gene sequence:

>906_bases
ATGACTGTTCAAAGAATACTTATCGTTGCAGGCACTCATGGGAATGAAATTAATCCTATTTGGGCTGTTAAGCAATTTAA
TAGAAATGAGAATAGTTTAAAACATGGGATTGAGTATGAGTACATCATAGGTAATCCTATTGCCTATGAAAAAGGCTGTA
GATATATAGATGCAGATTTAAATAGATCTTTTAAAAAAAGTAAGAATTATGATCAAAACGAGAATAGTTTTTATGAAATT
AGTAGAGCTAATTTTTTAGTAGATCAATTTGGAATTAATGGTTCTAAACCCTGTCAAATTGCTATCGATTTGCATACTAC
TACTGCAAATATGGGAACAAGTATTGTTATGTATGGGAGGAGATTTAAAGATTTTTGTTTAGCTGCATTACTCCAGAATA
AATTTGGATTGCCTATTTATTTACACGAAAAAGATAAATCCCAAACAGGGTTTCTTGTAGAAGCTTGGCCATGTGGCTTA
GTTATTGAAATAGGAGCTGTCGCACAAAATTTTTATGATCCAAAAATCATAAATAGATTTTTAATAATAATTAGCTCTTT
AAGGGACGAGATAGATAAATTGAAAAAAAACCTTATAGAACTACCAAAGGATTTGGTCGTTCACGTTCATCAAGGGAGTG
TAGATTATCCAAGAGATGAAAAAGGAGATATTGATGGCTTAATTCATCCAAAGAGAATAAACAGAGATTGGAAAATGATT
AAAAAAGGAGATCCATTATTTCTTAATAGCCAAGGGATTATTTATAAATATGATGGAGACCAGTTTATTTGGCCTGTTTT
TATTGGCGAAGTTGCTTACAAAGAAAAACAAATTGCGATGAGCTATACAAATAAAGAAGTGATTTGTTCCAAAAATGAAT
GGGTTCAAGAGTTTCACAGACTTTAA

Upstream 100 bases:

>100_bases
GCGAAACCATTCATCAATTGCATCCAAAACCAAAACCAAAATTTCTTGGAGGCCTTGATTAGGTATTTATTTTGCATAAG
ATTTTATTTTTAAAGAAAAA

Downstream 100 bases:

>100_bases
ATTTAAAAACCAAAACAATAAACTGCTGATAGCTAATAAGGATTTTTTATTTAATAGATAAGTTTATTTAATATTTAATG
CTCATGCTTTTTTTTGCTAA

Product: aspartoacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTVQRILIVAGTHGNEINPIWAVKQFNRNENSLKHGIEYEYIIGNPIAYEKGCRYIDADLNRSFKKSKNYDQNENSFYEI
SRANFLVDQFGINGSKPCQIAIDLHTTTANMGTSIVMYGRRFKDFCLAALLQNKFGLPIYLHEKDKSQTGFLVEAWPCGL
VIEIGAVAQNFYDPKIINRFLIIISSLRDEIDKLKKNLIELPKDLVVHVHQGSVDYPRDEKGDIDGLIHPKRINRDWKMI
KKGDPLFLNSQGIIYKYDGDQFIWPVFIGEVAYKEKQIAMSYTNKEVICSKNEWVQEFHRL

Sequences:

>Translated_301_residues
MTVQRILIVAGTHGNEINPIWAVKQFNRNENSLKHGIEYEYIIGNPIAYEKGCRYIDADLNRSFKKSKNYDQNENSFYEI
SRANFLVDQFGINGSKPCQIAIDLHTTTANMGTSIVMYGRRFKDFCLAALLQNKFGLPIYLHEKDKSQTGFLVEAWPCGL
VIEIGAVAQNFYDPKIINRFLIIISSLRDEIDKLKKNLIELPKDLVVHVHQGSVDYPRDEKGDIDGLIHPKRINRDWKMI
KKGDPLFLNSQGIIYKYDGDQFIWPVFIGEVAYKEKQIAMSYTNKEVICSKNEWVQEFHRL
>Mature_300_residues
TVQRILIVAGTHGNEINPIWAVKQFNRNENSLKHGIEYEYIIGNPIAYEKGCRYIDADLNRSFKKSKNYDQNENSFYEIS
RANFLVDQFGINGSKPCQIAIDLHTTTANMGTSIVMYGRRFKDFCLAALLQNKFGLPIYLHEKDKSQTGFLVEAWPCGLV
IEIGAVAQNFYDPKIINRFLIIISSLRDEIDKLKKNLIELPKDLVVHVHQGSVDYPRDEKGDIDGLIHPKRINRDWKMIK
KGDPLFLNSQGIIYKYDGDQFIWPVFIGEVAYKEKQIAMSYTNKEVICSKNEWVQEFHRL

Specific function: Unknown

COG id: COG2988

COG function: function code E; Succinylglutamate desuccinylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AspA/AstE family. Aspartoacylase subfamily

Homologues:

Organism=Homo sapiens, GI4557335, Length=300, Percent_Identity=33.3333333333333, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI189339202, Length=300, Percent_Identity=33.3333333333333, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI18087825, Length=291, Percent_Identity=28.8659793814433, Blast_Score=132, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASPA_PROM9 (Q31CV9)

Other databases:

- EMBL:   CP000111
- RefSeq:   YP_396722.1
- HSSP:   Q9R1T5
- ProteinModelPortal:   Q31CV9
- SMR:   Q31CV9
- STRING:   Q31CV9
- GeneID:   3765009
- GenomeReviews:   CP000111_GR
- KEGG:   pmi:PMT9312_0224
- eggNOG:   COG2988
- HOGENOM:   HBG635125
- OMA:   DFLIQMF
- ProtClustDB:   PRK02259
- BioCyc:   PMAR74546:PMT9312_0224-MONOMER
- HAMAP:   MF_00704
- InterPro:   IPR016708
- InterPro:   IPR007036
- PIRSF:   PIRSF018001

Pfam domain/function: PF04952 AstE_AspA

EC number: =3.5.1.15

Molecular weight: Translated: 34801; Mature: 34670

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: BINDING 54-54 BINDING 163-163 BINDING 273-273

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQRILIVAGTHGNEINPIWAVKQFNRNENSLKHGIEYEYIIGNPIAYEKGCRYIDADL
CCCEEEEEEEECCCCCCCEEEEEEECCCCCHHHHCCCEEEEEECCCEEHHHCCEEEEHHH
NRSFKKSKNYDQNENSFYEISRANFLVDQFGINGSKPCQIAIDLHTTTANMGTSIVMYGR
CHHHHHCCCCCCCCCCEEEEHHHEEEEECCCCCCCCCEEEEEEEEEEECCCCCEEEEECC
RFKDFCLAALLQNKFGLPIYLHEKDKSQTGFLVEAWPCGLVIEIGAVAQNFYDPKIINRF
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCEEEEECHHHHHCCCHHHHHHH
LIIISSLRDEIDKLKKNLIELPKDLVVHVHQGSVDYPRDEKGDIDGLIHPKRINRDWKMI
HHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCHHHH
KKGDPLFLNSQGIIYKYDGDQFIWPVFIGEVAYKEKQIAMSYTNKEVICSKNEWVQEFHR
CCCCCEEECCCCEEEEECCCEEEEHHHHHHHHHCCCEEEEEECCCEEEECCHHHHHHHHC
L
C
>Mature Secondary Structure 
TVQRILIVAGTHGNEINPIWAVKQFNRNENSLKHGIEYEYIIGNPIAYEKGCRYIDADL
CCEEEEEEEECCCCCCCEEEEEEECCCCCHHHHCCCEEEEEECCCEEHHHCCEEEEHHH
NRSFKKSKNYDQNENSFYEISRANFLVDQFGINGSKPCQIAIDLHTTTANMGTSIVMYGR
CHHHHHCCCCCCCCCCEEEEHHHEEEEECCCCCCCCCEEEEEEEEEEECCCCCEEEEECC
RFKDFCLAALLQNKFGLPIYLHEKDKSQTGFLVEAWPCGLVIEIGAVAQNFYDPKIINRF
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCEEEEECHHHHHCCCHHHHHHH
LIIISSLRDEIDKLKKNLIELPKDLVVHVHQGSVDYPRDEKGDIDGLIHPKRINRDWKMI
HHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCHHHH
KKGDPLFLNSQGIIYKYDGDQFIWPVFIGEVAYKEKQIAMSYTNKEVICSKNEWVQEFHR
CCCCCEEECCCCEEEEECCCEEEEHHHHHHHHHCCCEEEEEECCCEEEECCHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA