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The map label for this gene is nusG

Identifier: 78778593

GI number: 78778593

Start: 198023

End: 198634

Strand: Reverse

Name: nusG

Synonym: PMT9312_0207

Alternate gene names: 78778593

Gene position: 198634-198023 (Counterclockwise)

Preceding gene: 78778594

Following gene: 78778592

Centisome position: 11.62

GC content: 34.8

Gene sequence:

>612_bases
ATGAGTAATGAATTGACTACAAACCTTGCTTCTTCAAAAGCAAATACTAGCATCGCAAGATGGTATGCAGTTCAAGTAGC
ATCAAGCTGTGAAAAAAAAGTAAAAGCAACTCTTGAGCAAAGATCAGTAACTTTAGGAGTTAATAATCGAATTATTGAAA
TTGAAATCCCCCAAACTCCAGGAATTAAATTAAAAAAAGATGGAAGTAGACAAACCACCGAAGAAAAAGTTTTCCCAGGT
TATGTCTTAGTAAGAATGATTTTGGATGAAGATACAATGATGGCTGTAAAAAGTACTCCTAATGTAATTAACTTTGTTGG
TGCTGAAGACGGTAGAGGTAGTGGAAGATCTAGAGGTCATATCAAACCTCGACCATTATCCAGACAAGAAGTTAATAGAA
TCTTTAAGCGCGCATCAGAGAAAAAAGCTGTCATCAAGTTAGATATTGAAGAAAAAGATAGAATCTTAGTAACTAGTGGC
CCATTCAAGGATTTCCAGGGGGAAGTTATAGAAGTTTCCGGGGAAAGAAATAAATTAAAAGCATTACTTTCAATATTTGG
GCGCGAGACTCCTGTAGAATTAGAATTCTCCCAAATCAATAAACAAAATTAA

Upstream 100 bases:

>100_bases
CAGCAGATTCTATGGATGGGCAGCCTCACAAATTTTTGGTTGAATTATCCCTAAATATCCATTTTTATAAAGATCTTAAT
TAAGCTTCCAGTAAAAAAAA

Downstream 100 bases:

>100_bases
ATTCAAATAGTTCTTGTTTATCTAGTAAAATGATGATTTTCTACCTCAGCTTAAATTCTCTAATCTAATGGCAAAAAAAA
TTGTTGCAGTTATCAAGCTT

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MSNELTTNLASSKANTSIARWYAVQVASSCEKKVKATLEQRSVTLGVNNRIIEIEIPQTPGIKLKKDGSRQTTEEKVFPG
YVLVRMILDEDTMMAVKSTPNVINFVGAEDGRGSGRSRGHIKPRPLSRQEVNRIFKRASEKKAVIKLDIEEKDRILVTSG
PFKDFQGEVIEVSGERNKLKALLSIFGRETPVELEFSQINKQN

Sequences:

>Translated_203_residues
MSNELTTNLASSKANTSIARWYAVQVASSCEKKVKATLEQRSVTLGVNNRIIEIEIPQTPGIKLKKDGSRQTTEEKVFPG
YVLVRMILDEDTMMAVKSTPNVINFVGAEDGRGSGRSRGHIKPRPLSRQEVNRIFKRASEKKAVIKLDIEEKDRILVTSG
PFKDFQGEVIEVSGERNKLKALLSIFGRETPVELEFSQINKQN
>Mature_202_residues
SNELTTNLASSKANTSIARWYAVQVASSCEKKVKATLEQRSVTLGVNNRIIEIEIPQTPGIKLKKDGSRQTTEEKVFPGY
VLVRMILDEDTMMAVKSTPNVINFVGAEDGRGSGRSRGHIKPRPLSRQEVNRIFKRASEKKAVIKLDIEEKDRILVTSGP
FKDFQGEVIEVSGERNKLKALLSIFGRETPVELEFSQINKQN

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase [H]

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain [H]

Homologues:

Organism=Escherichia coli, GI1790414, Length=184, Percent_Identity=36.4130434782609, Blast_Score=116, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF00467 KOW; PF02357 NusG [H]

EC number: NA

Molecular weight: Translated: 22717; Mature: 22586

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNELTTNLASSKANTSIARWYAVQVASSCEKKVKATLEQRSVTLGVNNRIIEIEIPQTP
CCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEEECCCCC
GIKLKKDGSRQTTEEKVFPGYVLVRMILDEDTMMAVKSTPNVINFVGAEDGRGSGRSRGH
CEEEECCCCCCCCHHHCCCHHHEEHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCCCC
IKPRPLSRQEVNRIFKRASEKKAVIKLDIEEKDRILVTSGPFKDFQGEVIEVSGERNKLK
CCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCCCCCEEEECCCHHHHH
ALLSIFGRETPVELEFSQINKQN
HHHHHHCCCCCCEEEHHHCCCCC
>Mature Secondary Structure 
SNELTTNLASSKANTSIARWYAVQVASSCEKKVKATLEQRSVTLGVNNRIIEIEIPQTP
CCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEEECCCCC
GIKLKKDGSRQTTEEKVFPGYVLVRMILDEDTMMAVKSTPNVINFVGAEDGRGSGRSRGH
CEEEECCCCCCCCHHHCCCHHHEEHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCCCC
IKPRPLSRQEVNRIFKRASEKKAVIKLDIEEKDRILVTSGPFKDFQGEVIEVSGERNKLK
CCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCCCCCEEEECCCHHHHH
ALLSIFGRETPVELEFSQINKQN
HHHHHHCCCCCCEEEHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685084; 8905231; 7505271 [H]