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The map label for this gene is hisC1 [H]

Identifier: 78778574

GI number: 78778574

Start: 177680

End: 178789

Strand: Reverse

Name: hisC1 [H]

Synonym: PMT9312_0188

Alternate gene names: 78778574

Gene position: 178789-177680 (Counterclockwise)

Preceding gene: 78778575

Following gene: 78778567

Centisome position: 10.46

GC content: 27.39

Gene sequence:

>1110_bases
ATGAATGATTTTGATCCATTAAATAATCTTTTCCCAAAACCAAGAGAAGAAATAATAAATATGCAGTCTTACTCTGCACC
TTTAGAAAATAGAAGAAATTTACTCCGCTTAGACTTTAATGAAAATACTTTAGGTCCAAGTCCTAAGGTTTTAGAGGCAT
TACAAGCGATAAAATTAGATGAGATTTCAATTTATCCAGAATATAATTTTTTAAAAAAATTTTTATGTGATAAATATCTT
GATTCAAGAAAATTTGGTAATGATGAAATCGGAATTTTCAATGGAGCAGATGCAGCAATAAATGCAATTTTCAATTGCTT
TGGAGAAAAAGATCAAATATTTCTAACCACAAATCCAACTTTTGGTTACTATTCTCCTTGTGCAGAAATGCGAGGAATGA
AAAAAATAAGTTGTTCTTACATTGGAGAAAATTTCCTATTCCCCATCGAAGAATTTAGGGAAAAAATAATAAAGCATAAT
CCAAAGTTAATATTTATTTGCAATCCAAATAATCCAACAGGAACGGTTATAAGCTCTCAGGAAATAATTAACTTAGCTAA
TATCAATCACGATTCATTAATAATTGTTGATGAACTATATGAAAAATTTAATGGAGATAGTCTTCTTGAATCGATAGATT
TTGAAAAGAATAACAATATACTAATAATCCAATCTCTTTCAAAAACTGCAGGTTTAGCTGGTTTAAGAATAGGTTTTACT
TTTGGCAATAAAATTTTAATACAGTACATTAATAATGTTACAGGACCATATGATGTAAATAGCTTTGCTATAACAGCAGC
ATTAGCAGCACTTAAAGACAAATCATATATTGATAATTATGTTTTAGAAGTAAAAAAGGCGAGAGAATGGATTTTAAATA
AATTTAAATCAACAAAAATCAGAACTCACTTTAGTGGAGGTAATTATTTCTTAATTTGGCCAATAAAAGATCCTAAAATC
TTAATACAAAAGATGAGAGAAAAAGGTATTCTTATTAGAAGTATGGAAAACAAAAAAGATATTGGTGACTCAATAAGGGT
TAGTATTGGAACTAAAGAACAAATGATTTTTTTCTGGGAAAATTACAAGATCTTAGATTTAATAAATTAA

Upstream 100 bases:

>100_bases
AAAATATAAAAATTTCTAGACTTAATTTATGTGACCTAACTGCAAAAACACTAAAATTAAGCTTAGAGCTTTTAGGAATT
GAAACTTTAGAAAGAATGTA

Downstream 100 bases:

>100_bases
TTACTGAAAATATAAATTGTATTTTGATCGATTCTTTTAGGTTTTATTTGAAAATCTTTTCCAACATATTTTACTTGAAA
ATCTTTCATATTTTCGATAA

Product: histidinol phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 1 [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MNDFDPLNNLFPKPREEIINMQSYSAPLENRRNLLRLDFNENTLGPSPKVLEALQAIKLDEISIYPEYNFLKKFLCDKYL
DSRKFGNDEIGIFNGADAAINAIFNCFGEKDQIFLTTNPTFGYYSPCAEMRGMKKISCSYIGENFLFPIEEFREKIIKHN
PKLIFICNPNNPTGTVISSQEIINLANINHDSLIIVDELYEKFNGDSLLESIDFEKNNNILIIQSLSKTAGLAGLRIGFT
FGNKILIQYINNVTGPYDVNSFAITAALAALKDKSYIDNYVLEVKKAREWILNKFKSTKIRTHFSGGNYFLIWPIKDPKI
LIQKMREKGILIRSMENKKDIGDSIRVSIGTKEQMIFFWENYKILDLIN

Sequences:

>Translated_369_residues
MNDFDPLNNLFPKPREEIINMQSYSAPLENRRNLLRLDFNENTLGPSPKVLEALQAIKLDEISIYPEYNFLKKFLCDKYL
DSRKFGNDEIGIFNGADAAINAIFNCFGEKDQIFLTTNPTFGYYSPCAEMRGMKKISCSYIGENFLFPIEEFREKIIKHN
PKLIFICNPNNPTGTVISSQEIINLANINHDSLIIVDELYEKFNGDSLLESIDFEKNNNILIIQSLSKTAGLAGLRIGFT
FGNKILIQYINNVTGPYDVNSFAITAALAALKDKSYIDNYVLEVKKAREWILNKFKSTKIRTHFSGGNYFLIWPIKDPKI
LIQKMREKGILIRSMENKKDIGDSIRVSIGTKEQMIFFWENYKILDLIN
>Mature_369_residues
MNDFDPLNNLFPKPREEIINMQSYSAPLENRRNLLRLDFNENTLGPSPKVLEALQAIKLDEISIYPEYNFLKKFLCDKYL
DSRKFGNDEIGIFNGADAAINAIFNCFGEKDQIFLTTNPTFGYYSPCAEMRGMKKISCSYIGENFLFPIEEFREKIIKHN
PKLIFICNPNNPTGTVISSQEIINLANINHDSLIIVDELYEKFNGDSLLESIDFEKNNNILIIQSLSKTAGLAGLRIGFT
FGNKILIQYINNVTGPYDVNSFAITAALAALKDKSYIDNYVLEVKKAREWILNKFKSTKIRTHFSGGNYFLIWPIKDPKI
LIQKMREKGILIRSMENKKDIGDSIRVSIGTKEQMIFFWENYKILDLIN

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=311, Percent_Identity=25.08038585209, Blast_Score=107, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322075, Length=382, Percent_Identity=26.7015706806283, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 42386; Mature: 42386

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDFDPLNNLFPKPREEIINMQSYSAPLENRRNLLRLDFNENTLGPSPKVLEALQAIKLD
CCCCCCHHHCCCCCHHHHHCHHHCCCCHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCC
EISIYPEYNFLKKFLCDKYLDSRKFGNDEIGIFNGADAAINAIFNCFGEKDQIFLTTNPT
EEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHCCCCCEEEEEECCC
FGYYSPCAEMRGMKKISCSYIGENFLFPIEEFREKIIKHNPKLIFICNPNNPTGTVISSQ
CCCCCCHHHHCCCCEEHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEHH
EIINLANINHDSLIIVDELYEKFNGDSLLESIDFEKNNNILIIQSLSKTAGLAGLRIGFT
HHEEEECCCCCCEEEHHHHHHHCCCCHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEEE
FGNKILIQYINNVTGPYDVNSFAITAALAALKDKSYIDNYVLEVKKAREWILNKFKSTKI
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCEE
RTHFSGGNYFLIWPIKDPKILIQKMREKGILIRSMENKKDIGDSIRVSIGTKEQMIFFWE
EEEECCCCEEEEEECCCHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEECCCCEEEEEEC
NYKILDLIN
CEEEEEECC
>Mature Secondary Structure
MNDFDPLNNLFPKPREEIINMQSYSAPLENRRNLLRLDFNENTLGPSPKVLEALQAIKLD
CCCCCCHHHCCCCCHHHHHCHHHCCCCHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCC
EISIYPEYNFLKKFLCDKYLDSRKFGNDEIGIFNGADAAINAIFNCFGEKDQIFLTTNPT
EEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHCCCCCEEEEEECCC
FGYYSPCAEMRGMKKISCSYIGENFLFPIEEFREKIIKHNPKLIFICNPNNPTGTVISSQ
CCCCCCHHHHCCCCEEHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEHH
EIINLANINHDSLIIVDELYEKFNGDSLLESIDFEKNNNILIIQSLSKTAGLAGLRIGFT
HHEEEECCCCCCEEEHHHHHHHCCCCHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEEE
FGNKILIQYINNVTGPYDVNSFAITAALAALKDKSYIDNYVLEVKKAREWILNKFKSTKI
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCEE
RTHFSGGNYFLIWPIKDPKILIQKMREKGILIRSMENKKDIGDSIRVSIGTKEQMIFFWE
EEEECCCCEEEEEECCCHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEECCCCEEEEEEC
NYKILDLIN
CEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA