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The map label for this gene is yycF [H]

Identifier: 78778522

GI number: 78778522

Start: 132653

End: 133399

Strand: Direct

Name: yycF [H]

Synonym: PMT9312_0136

Alternate gene names: 78778522

Gene position: 132653-133399 (Clockwise)

Preceding gene: 78778520

Following gene: 78778523

Centisome position: 7.76

GC content: 37.48

Gene sequence:

>747_bases
ATGGCTGGATCTAGTCAAACTAAAGAAACAATCCTTGTCGCAGATGATGAGGCAAGTATTAGAAGAATTCTGGAGACGCG
TCTCTCCATGATTGGCTACAAAGTTGTAACTGCAAGTGATGGTAAAGAAGCACTAAAGTTATTTAAAGATTATGAGCCTG
ATCTAGTAGTACTAGACGTCATGATGCCAAAGTTAGACGGTTATGGAGTGTGTCAAGAATTAAGGAAAGATTCTGATGTT
CCAATTGTTATGTTAACTGCATTAGGAGATGTTGCAGATAGGATAACAGGTTTAGAATTAGGAGCTGATGACTATGTAGT
TAAACCATTTAGTCCCAAGGAATTAGAAGCTAGAATTAGGTGTGTTCTTAGAAGAATTGACAAGGATCAAATTCCTGGGA
TGCCTAATTCAGGTTTGATTTTGGTTACTGATATAAAAATTGATACCAATAGAAGACAAGTTTTTAAAAGCGATGAGAGA
ATTAGATTAACTGGGATGGAATTTAGTCTCCTAGAGCTTTTGGTAAGTAGGTCAGGAGAACCATTTAGTAGAGGAGAGAT
TTTAAAAGAGGTTTGGGGATATACACCTGAGAGGCATGTAGATACAAGAGTAGTCGATGTTCATATATCGAGATTAAGGT
CAAAACTGGAGGCCGATCCGGCCAATCCTGAATTGATACTAACAGCAAGAGGCACAGGATATCTTTTTCAAAGGATTGTC
GATATTGCTCCTTTTGATGGTAAATAA

Upstream 100 bases:

>100_bases
TTAAAAAAGTACATGGAACTAGAATGTTTGGGATATTGCCCCTCTACAAGTTAGATTAGGTTAATAACAAATTCTCATAC
TGATTAGCTAATAGAAACAA

Downstream 100 bases:

>100_bases
ATGGGAAAAGAAACTTTACCTAAAAATAATAAGTCCAGAGCTATCAGAAGATTGGTTATTTGGTATAAAAGAAACTCGGC
TGTAACTTCTATAGTTGATA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MAGSSQTKETILVADDEASIRRILETRLSMIGYKVVTASDGKEALKLFKDYEPDLVVLDVMMPKLDGYGVCQELRKDSDV
PIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRCVLRRIDKDQIPGMPNSGLILVTDIKIDTNRRQVFKSDER
IRLTGMEFSLLELLVSRSGEPFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEADPANPELILTARGTGYLFQRIV
DIAPFDGK

Sequences:

>Translated_248_residues
MAGSSQTKETILVADDEASIRRILETRLSMIGYKVVTASDGKEALKLFKDYEPDLVVLDVMMPKLDGYGVCQELRKDSDV
PIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRCVLRRIDKDQIPGMPNSGLILVTDIKIDTNRRQVFKSDER
IRLTGMEFSLLELLVSRSGEPFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEADPANPELILTARGTGYLFQRIV
DIAPFDGK
>Mature_247_residues
AGSSQTKETILVADDEASIRRILETRLSMIGYKVVTASDGKEALKLFKDYEPDLVVLDVMMPKLDGYGVCQELRKDSDVP
IVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRCVLRRIDKDQIPGMPNSGLILVTDIKIDTNRRQVFKSDERI
RLTGMEFSLLELLVSRSGEPFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEADPANPELILTARGTGYLFQRIVD
IAPFDGK

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=41.8803418803419, Blast_Score=174, Evalue=4e-45,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=39.7379912663755, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=35.2422907488987, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=37.9310344827586, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=39.8230088495575, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=37.0044052863436, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=37.5, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=33.6170212765957, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=40.8695652173913, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=33.1896551724138, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=33.0396475770925, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=31.7180616740088, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=32.8888888888889, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=34.1880341880342, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=39.622641509434, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=29.2682926829268, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=34.2105263157895, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=32.5, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI145693157, Length=121, Percent_Identity=32.2314049586777, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788713, Length=105, Percent_Identity=37.1428571428571, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=123, Percent_Identity=35.7723577235772, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27836; Mature: 27704

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSSQTKETILVADDEASIRRILETRLSMIGYKVVTASDGKEALKLFKDYEPDLVVLDV
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCCEEEEEE
MMPKLDGYGVCQELRKDSDVPIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIR
HHCCCCCCHHHHHHHCCCCCCEEEEEHHHHHHHHHHCCEECCCCEEECCCCCHHHHHHHH
CVLRRIDKDQIPGMPNSGLILVTDIKIDTNRRQVFKSDERIRLTGMEFSLLELLVSRSGE
HHHHHHCHHHCCCCCCCCEEEEEEEEECCCHHHHHCCCCEEEEECCCHHHHHHHHHCCCC
PFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEADPANPELILTARGTGYLFQRIV
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHH
DIAPFDGK
HCCCCCCC
>Mature Secondary Structure 
AGSSQTKETILVADDEASIRRILETRLSMIGYKVVTASDGKEALKLFKDYEPDLVVLDV
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCCEEEEEE
MMPKLDGYGVCQELRKDSDVPIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIR
HHCCCCCCHHHHHHHCCCCCCEEEEEHHHHHHHHHHCCEECCCCEEECCCCCHHHHHHHH
CVLRRIDKDQIPGMPNSGLILVTDIKIDTNRRQVFKSDERIRLTGMEFSLLELLVSRSGE
HHHHHHCHHHCCCCCCCCEEEEEEEEECCCHHHHHCCCCEEEEECCCHHHHHHHHHCCCC
PFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEADPANPELILTARGTGYLFQRIV
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHH
DIAPFDGK
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]